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Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors.

Gay NJ.

BMC Biol. 2019 Feb 20;17(1):15. doi: 10.1186/s12915-019-0637-5.


Factor Structure and Psychometric Properties of the Peritraumatic and Posttraumatic Emotions Questionnaires Among Active Duty Military Personnel With Posttraumatic Stress Disorder.

Zang Y, Gay NG, Kaczkurkin AN, McLean CP, Wachen JS, Yarvis JS, Litz BT, Yadin E, Mintz J, Roache JD, Young-McCaughan S, Peterson AL, Foa EB, Resick PA; STRONG STAR Consortium.

J Trauma Stress. 2018 Dec;31(6):826-836. doi: 10.1002/jts.22350. Epub 2018 Dec 12.


Colorectal Lymphoma: A Review.

Gay ND, Chen A, Okada CY.

Clin Colon Rectal Surg. 2018 Sep;31(5):309-316. doi: 10.1055/s-0038-1642048. Epub 2018 Sep 4. Review.


Examination of posttraumatic stress disorder symptom networks using clinician-rated and patient-rated data.

Moshier SJ, Bovin MJ, Gay NG, Wisco BE, Mitchell KS, Lee DJ, Sloan DM, Weathers FW, Schnurr PP, Keane TM, Marx BP.

J Abnorm Psychol. 2018 Aug;127(6):541-547. doi: 10.1037/abn0000368.


Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design.

de Groot AM, Thanki K, Gangloff M, Falkenberg E, Zeng X, van Bijnen DCJ, van Eden W, Franzyk H, Nielsen HM, Broere F, Gay NJ, Foged C, Sijts AJAM.

Mol Ther Nucleic Acids. 2018 Jun 1;11:159-169. doi: 10.1016/j.omtn.2018.02.003. Epub 2018 Feb 13.


Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation.

Ezzoukhry Z, Henriet E, Cordelières FP, Dupuy JW, Maître M, Gay N, Di-Tommaso S, Mercier L, Goetz JG, Peter M, Bard F, Moreau V, Raymond AA, Saltel F.

Nat Commun. 2018 May 23;9(1):2031. doi: 10.1038/s41467-018-04461-9.


Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons.

Ritchie L, Tate R, Chamberlain LH, Robertson G, Zagnoni M, Sposito T, Wray S, Wright JA, Bryant CE, Gay NJ, Bushell TJ.

Neuropharmacology. 2018 Jun;135:1-10. doi: 10.1016/j.neuropharm.2018.02.025. Epub 2018 Mar 2.


Risk Factors of Extended-Spectrum β-Lactamase Producing Enterobacteriaceae Occurrence in Farms in Reunion, Madagascar and Mayotte Islands, 2016-2017.

Gay N, Leclaire A, Laval M, Miltgen G, Jégo M, Stéphane R, Jaubert J, Belmonte O, Cardinale E.

Vet Sci. 2018 Feb 23;5(1). pii: E22. doi: 10.3390/vetsci5010022.


Neuroprotective Effects of Phenolic and Carboxylic Acids on Oxidative Stress-Induced Toxicity in Human Neuroblastoma SH-SY5Y Cells.

Gay NH, Phopin K, Suwanjang W, Songtawee N, Ruankham W, Wongchitrat P, Prachayasittikul S, Prachayasittikul V.

Neurochem Res. 2018 Mar;43(3):619-636. doi: 10.1007/s11064-017-2463-x. Epub 2018 Feb 7.


Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub.

Latty SL, Sakai J, Hopkins L, Verstak B, Paramo T, Berglund NA, Cammarota E, Cicuta P, Gay NJ, Bond PJ, Klenerman D, Bryant CE.

Elife. 2018 Jan 24;7. pii: e31377. doi: 10.7554/eLife.31377.


ReprDB and panDB: minimalist databases with maximal microbial representation.

Zhou W, Gay N, Oh J.

Microbiome. 2018 Jan 18;6(1):15. doi: 10.1186/s40168-018-0399-2.


Targeting and Recognition of Toll-Like Receptors by Plant and Pathogen Lectins.

Ricci-Azevedo R, Roque-Barreira MC, Gay NJ.

Front Immunol. 2017 Dec 18;8:1820. doi: 10.3389/fimmu.2017.01820. eCollection 2017.


Obinutuzumab monotherapy in previously untreated chronic lymphocytic leukemia.

Gay ND, Kozin E, Okada C, Danilov AV, Spurgeon S.

Leuk Lymphoma. 2018 Sep;59(9):2258-2260. doi: 10.1080/10428194.2017.1410890. Epub 2017 Dec 18. No abstract available.


Outcomes of DA-EPOCH-R induction plus autologous transplant consolidation for double hit lymphoma.

Chen AI, Leonard JT, Okada CY, Gay ND, Chansky K, Fan G, Dunlap JB, Raess PW, Braziel RM, Stentz A, Maziarz RT.

Leuk Lymphoma. 2018 Aug;59(8):1884-1889. doi: 10.1080/10428194.2017.1406085. Epub 2017 Dec 3.


Ferrofluid-Based Droplet Interface Bilayer Networks.

Makhoul-Mansour M, Zhao W, Gay N, O'Connor C, Najem JS, Mao L, Freeman EC.

Langmuir. 2017 Nov 14;33(45):13000-13007. doi: 10.1021/acs.langmuir.7b03055. Epub 2017 Nov 3.


Management of severe factor XI deficiency in cardiac surgery: A case report and review of the literature.

Gay ND, Azar S, Salomon O, Taylor JA.

Haemophilia. 2017 Nov;23(6):e512-e514. doi: 10.1111/hae.13311. Epub 2017 Aug 31. No abstract available.


Kek-6: A truncated-Trk-like receptor for Drosophila neurotrophin 2 regulates structural synaptic plasticity.

Ulian-Benitez S, Bishop S, Foldi I, Wentzell J, Okenwa C, Forero MG, Zhu B, Moreira M, Phizacklea M, McIlroy G, Li G, Gay NJ, Hidalgo A.

PLoS Genet. 2017 Aug 28;13(8):e1006968. doi: 10.1371/journal.pgen.1006968. eCollection 2017 Aug.


Review of Antibiotic Resistance in the Indian Ocean Commission: A Human and Animal Health Issue.

Gay N, Belmonte O, Collard JM, Halifa M, Issack MI, Mindjae S, Palmyre P, Ibrahim AA, Rasamoelina H, Flachet L, Filleul L, Cardinale E.

Front Public Health. 2017 Jul 6;5:162. doi: 10.3389/fpubh.2017.00162. eCollection 2017. Review.


Cognitive Emotion Regulation Strategies Associated With the DSM-5 Posttraumatic Stress Disorder Criteria.

Kaczkurkin AN, Zang Y, Gay NG, Peterson AL, Yarvis JS, Borah EV, Dondanville KA, Hembree EA, Litz BT, Mintz J, Young-McCaughan S, Foa EB; STRONG STAR Consortium.

J Trauma Stress. 2017 Aug;30(4):343-350. doi: 10.1002/jts.22202. Epub 2017 Jun 30.


Unexpected pharmacokinetics of recombinant porcine factor VIII in a patient with acquired factor VIII deficiency and spontaneous epidural haematoma.

Shatzel JJ, Azar S, Scherber R, Gay N, Deloughery TG, VanSandt A, Kruse-Jarres R, Recht M, Taylor JA.

Haemophilia. 2017 Sep;23(5):e453-e456. doi: 10.1111/hae.13247. Epub 2017 Jun 29. No abstract available.


Internet-Based Exercise Therapy Using Algorithms for Conservative Treatment of Anterior Knee Pain: A Pragmatic Randomized Controlled Trial.

Kim TWB, Gay N, Khemka A, Garino J.

JMIR Rehabil Assist Technol. 2016 Dec 14;3(2):e12. doi: 10.2196/rehab.5148.


Psychiatric Symptoms and Barriers to Care in HIV-Infected Individuals Who Are Lost to Care.

McLean CP, Gay NG, Metzger DA, Foa EB; Penn Mental Health AIDS Research Center.

J Int Assoc Provid AIDS Care. 2017 Sep/Oct;16(5):423-429. doi: 10.1177/2325957417711254. Epub 2017 Jun 5.


Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis.

Fels Elliott DR, Perner J, Li X, Symmons MF, Verstak B, Eldridge M, Bower L, O'Donovan M, Gay NJ; OCCAMS Consortium, Fitzgerald RC.

PLoS Genet. 2017 May 22;13(5):e1006808. doi: 10.1371/journal.pgen.1006808. eCollection 2017 May.


Durable Response to Afatinib in Lung Adenocarcinoma Harboring NRG1 Gene Fusions.

Gay ND, Wang Y, Beadling C, Warrick A, Neff T, Corless CL, Tolba K.

J Thorac Oncol. 2017 Aug;12(8):e107-e110. doi: 10.1016/j.jtho.2017.04.025. Epub 2017 May 10. No abstract available.


Targeting the programmed cell death 1 pathway in Hodgkin lymphoma: the place of nivolumab.

Gay ND, Okada CY, Chen AI, Scott EC.

Ther Adv Hematol. 2017 May;8(5):175-180. doi: 10.1177/2040620717695723. Epub 2017 Mar 28. Review.


Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila.

Foldi I, Anthoney N, Harrison N, Gangloff M, Verstak B, Nallasivan MP, AlAhmed S, Zhu B, Phizacklea M, Losada-Perez M, Moreira M, Gay NJ, Hidalgo A.

J Cell Biol. 2017 May 1;216(5):1421-1438. doi: 10.1083/jcb.201607098. Epub 2017 Apr 3.


Toll-like receptor 2 promiscuity is responsible for the immunostimulatory activity of nucleic acid nanocarriers.

Pizzuto M, Gangloff M, Scherman D, Gay NJ, Escriou V, Ruysschaert JM, Lonez C.

J Control Release. 2017 Feb 10;247:182-193. doi: 10.1016/j.jconrel.2016.12.029. Epub 2016 Dec 28.


Draft Genome Sequence of Cloacibacterium normanense NRS-1 Isolated from Municipal Wastewater.

Gay NR, Fleming E, Oh J.

Genome Announc. 2016 Dec 15;4(6). pii: e01397-16. doi: 10.1128/genomeA.01397-16.


Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome.

Halabi S, Sekine E, Verstak B, Gay NJ, Moncrieffe MC.

J Biol Chem. 2017 Jan 13;292(2):652-660. doi: 10.1074/jbc.M116.761528. Epub 2016 Dec 1.


The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold.

Dossang AC, Motshwene PG, Yang Y, Symmons MF, Bryant CE, Borman S, George J, Weber AN, Gay NJ.

Sci Rep. 2016 Nov 23;6:37267. doi: 10.1038/srep37267.


Predictors of suicidal ideation among active duty military personnel with posttraumatic stress disorder.

McLean CP, Zang Y, Zandberg L, Bryan CJ, Gay N, Yarvis JS, Foa EB; STRONG STAR Consortium.

J Affect Disord. 2017 Jan 15;208:392-398. doi: 10.1016/j.jad.2016.08.061. Epub 2016 Nov 23.


Zika emergence in the French Territories of America and description of first confirmed cases of Zika virus infection on Martinique, November 2015 to February 2016.

Daudens-Vaysse E, Ledrans M, Gay N, Ardillon V, Cassadou S, Najioullah F, Leparc-Goffart I, Rousset D, Herrmann C, Cesaire R, Maquart M, Flusin O, Matheus S, Huc-Anaïs P, Jaubert J, Criquet-Hayot A, Hoen B, Djossou F, Locatelli-Jouans C, Blateau A, McKenzie AM, Melin M, Saint-Martin P, Dorléans F, Suivant C, Carvalho L, Petit-Sinturel M, Andrieu A, Noël H, Septfons A, Gallay A, Paty MC, Filleul L, Cabié A; Zika Surveillance Working Group.

Euro Surveill. 2016 Jul 14;21(28). doi: 10.2807/1560-7917.ES.2016.21.28.30285.


Reconstructing a spatially heterogeneous epidemic: Characterising the geographic spread of 2009 A/H1N1pdm infection in England.

Birrell PJ, Zhang XS, Pebody RG, Gay NJ, De Angelis D.

Sci Rep. 2016 Jul 11;6:29004. doi: 10.1038/srep29004.


Bioinformatic Analysis of Toll-Like Receptor Sequences and Structures.

Monie TP, Gay NJ, Gangloff M.

Methods Mol Biol. 2016;1390:29-39. doi: 10.1007/978-1-4939-3335-8_2.


Seroprevalence of Asian Lineage Chikungunya Virus Infection on Saint Martin Island, 7 Months After the 2013 Emergence.

Gay N, Rousset D, Huc P, Matheus S, Ledrans M, Rosine J, Cassadou S, Noël H.

Am J Trop Med Hyg. 2016 Feb;94(2):393-396. doi: 10.4269/ajtmh.15-0308. Epub 2015 Dec 7.


The supramammillary nucleus and the claustrum activate the cortex during REM sleep.

Renouard L, Billwiller F, Ogawa K, Clément O, Camargo N, Abdelkarim M, Gay N, Scoté-Blachon C, Touré R, Libourel PA, Ravassard P, Salvert D, Peyron C, Claustrat B, Léger L, Salin P, Malleret G, Fort P, Luppi PH.

Sci Adv. 2015 Apr 3;1(3):e1400177. doi: 10.1126/sciadv.1400177. eCollection 2015 Apr.


Sleep architecture and homeostasis in mice with partial ablation of melanin-concentrating hormone neurons.

Varin C, Arthaud S, Salvert D, Gay N, Libourel PA, Luppi PH, Léger L, Fort P.

Behav Brain Res. 2016 Feb 1;298(Pt B):100-10. doi: 10.1016/j.bbr.2015.10.051. Epub 2015 Oct 31.


Yeast expressed ArtinM shares structure, carbohydrate recognition, and biological effects with native ArtinM.

Cecílio NT, Carvalho FC, Liu Y, Moncrieffe M, Buranello PA, Zorzetto-Fernandes AL, Luche DD, Hanna ES, Soares SG, Feizi T, Gay NJ, Goldman MH, Roque-Barreira MC.

Int J Biol Macromol. 2016 Jan;82:22-30. doi: 10.1016/j.ijbiomac.2015.09.062. Epub 2015 Oct 1.


Chronic Intermittent Hypoxia Induces Chronic Low-Grade Neuroinflammation in the Dorsal Hippocampus of Mice.

Sapin E, Peyron C, Roche F, Gay N, Carcenac C, Savasta M, Levy P, Dematteis M.

Sleep. 2015 Oct 1;38(10):1537-46. doi: 10.5665/sleep.5042.


Critical residues involved in Toll-like receptor 4 activation by cationic lipid nanocarriers are not located at the lipopolysaccharide-binding interface.

Lonez C, Irvine KL, Pizzuto M, Schmidt BI, Gay NJ, Ruysschaert JM, Gangloff M, Bryant CE.

Cell Mol Life Sci. 2015 Oct;72(20):3971-82. doi: 10.1007/s00018-015-1915-1. Epub 2015 May 9.


Advances in Toll-like receptor biology: Modes of activation by diverse stimuli.

Bryant CE, Gay NJ, Heymans S, Sacre S, Schaefer L, Midwood KS.

Crit Rev Biochem Mol Biol. 2015;50(5):359-79. doi: 10.3109/10409238.2015.1033511. Epub 2015 Apr 10. Review.


Increased fracture rates in people with haemophilia: a 10-year single institution retrospective analysis.

Gay ND, Lee SC, Liel MS, Sochacki P, Recht M, Taylor JA.

Br J Haematol. 2015 Aug;170(4):584-6. doi: 10.1111/bjh.13312. Epub 2015 Feb 6. No abstract available.


Paradoxical (REM) sleep deprivation in mice using the small-platforms-over-water method: polysomnographic analyses and melanin-concentrating hormone and hypocretin/orexin neuronal activation before, during and after deprivation.

Arthaud S, Varin C, Gay N, Libourel PA, Chauveau F, Fort P, Luppi PH, Peyron C.

J Sleep Res. 2015 Jun;24(3):309-19. doi: 10.1111/jsr.12269. Epub 2014 Dec 18.


Therapeutic administration of recombinant Paracoccin confers protection against paracoccidioides brasiliensis infection: involvement of TLRs.

Alegre-Maller AC, Mendonça FC, da Silva TA, Oliveira AF, Freitas MS, Hanna ES, Almeida IC, Gay NJ, Roque-Barreira MC.

PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3317. doi: 10.1371/journal.pntd.0003317. eCollection 2014 Dec.


Refeeding syndrome: unrecognized in geriatric medicine.

Coutaz M, Gay N.

J Am Med Dir Assoc. 2014;15(11):848-9. doi: 10.1016/j.jamda.2014.08.019. No abstract available.


The TLR4 D299G and T399I SNPs are constitutively active to up-regulate expression of Trif-dependent genes.

Hold GL, Berry S, Saunders KA, Drew J, Mayer C, Brookes H, Gay NJ, El-Omar EM, Bryant CE.

PLoS One. 2014 Nov 3;9(11):e111460. doi: 10.1371/journal.pone.0111460. eCollection 2014.


Molecular and cellular regulation of toll-like receptor-4 activity induced by lipopolysaccharide ligands.

Liaunardy-Jopeace A, Gay NJ.

Front Immunol. 2014 Oct 6;5:473. doi: 10.3389/fimmu.2014.00473. eCollection 2014. Review.


Parasite and viral species richness of Southeast Asian bats: Fragmentation of area distribution matters.

Gay N, Olival KJ, Bumrungsri S, Siriaroonrat B, Bourgarel M, Morand S.

Int J Parasitol Parasites Wildl. 2014 Jul 8;3(2):161-70. doi: 10.1016/j.ijppaw.2014.06.003. eCollection 2014 Aug.


Epidemiology of varicella zoster virus infection in Canada and the United Kingdom - CORRIGENDUM.

Brisson M, Edmunds WJ, Law B, Gay NJ, Walld R, Brownell M, Roos LL, DE Serres G.

Epidemiol Infect. 2015 Apr;143(6):1332. doi: 10.1017/S0950268814002088. Epub 2014 Aug 13. No abstract available.


Toll-like receptor signalling through macromolecular protein complexes.

Bryant CE, Symmons M, Gay NJ.

Mol Immunol. 2015 Feb;63(2):162-5. doi: 10.1016/j.molimm.2014.06.033. Epub 2014 Jul 28. Review.


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