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Decision regret in men living with and beyond non-metastatic prostate cancer in the UK: a population-based patient-reported outcome study.

Wilding S, Downing A, Selby P, Cross W, Wright P, Watson EK, Wagland R, Kind P, Donnelly DW, Hounsome L, Mottram R, Allen M, Kearney T, Butcher H, Gavin A, Glaser A.

Psychooncology. 2020 Feb 17. doi: 10.1002/pon.5362. [Epub ahead of print]


Dynamic Buffering of Extracellular Chemokine by a Dedicated Scavenger Pathway Enables Robust Adaptation during Directed Tissue Migration.

Wong M, Newton LR, Hartmann J, Hennrich ML, Wachsmuth M, Ronchi P, Guzmán-Herrera A, Schwab Y, Gavin AC, Gilmour D.

Dev Cell. 2020 Feb 7. pii: S1534-5807(20)30014-9. doi: 10.1016/j.devcel.2020.01.013. [Epub ahead of print]


Exploring variations in ovarian cancer survival by age and stage (ICBP SurvMark-2): A population-based study.

Cabasag CJ, Butler J, Arnold M, Rutherford M, Bardot A, Ferlay J, Morgan E, Møller B, Gavin A, Norell CH, Harrison S, Saint-Jacques N, Eden M, Rous B, Nordin A, Hanna L, Kwon J, Cohen PA, Altman AD, Shack L, Kozie S, Engholm G, De P, Sykes P, Porter G, Ferguson S, Walsh P, Trevithick R, O'Connell D, Bray F, Soerjomataram I.

Gynecol Oncol. 2020 Jan 28. pii: S0090-8258(19)31877-3. doi: 10.1016/j.ygyno.2019.12.047. [Epub ahead of print]


Pain, fatigue and depression symptom cluster in survivors of prostate cancer.

Baden M, Lu L, Drummond FJ, Gavin A, Sharp L.

Support Care Cancer. 2020 Jan 24. doi: 10.1007/s00520-019-05268-0. [Epub ahead of print]


Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes.

Liu Y, Bunney TD, Khosa S, Macé K, Beckenbauer K, Askwith T, Maslen S, Stubbs C, de Oliveira TM, Sader K, Skehel M, Gavin AC, Phillips C, Katan M.

EBioMedicine. 2020 Jan;51:102607. doi: 10.1016/j.ebiom.2019.102607. Epub 2020 Jan 6.


Time intervals and routes to diagnosis for lung cancer in 10 jurisdictions: cross-sectional study findings from the International Cancer Benchmarking Partnership (ICBP).

Menon U, Vedsted P, Zalounina Falborg A, Jensen H, Harrison S, Reguilon I, Barisic A, Bergin RJ, Brewster DH, Butler J, Brustugun OT, Bucher O, Cairnduff V, Gavin A, Grunfeld E, Harland E, Kalsi J, Knudsen AK, Lambe M, Law RJ, Lin Y, Malmberg M, Turner D, Neal RD, White V, Weller D.

BMJ Open. 2019 Nov 27;9(11):e025895. doi: 10.1136/bmjopen-2018-025895.


Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors.

Foster SR, Hauser AS, Vedel L, Strachan RT, Huang XP, Gavin AC, Shah SD, Nayak AP, Haugaard-Kedström LM, Penn RB, Roth BL, Bräuner-Osborne H, Gloriam DE.

Cell. 2019 Oct 31;179(4):895-908.e21. doi: 10.1016/j.cell.2019.10.010.


Adjustment strategies amongst black African and black Caribbean men following treatment for prostate cancer: Findings from the Life After Prostate Cancer Diagnosis (LAPCD) study.

Wagland R, Nayoan J, Matheson L, Rivas C, Brett J, Collaco N, Alexis O, Gavin A, Glaser AW, Watson E.

Eur J Cancer Care (Engl). 2020 Jan;29(1):e13183. doi: 10.1111/ecc.13183. Epub 2019 Oct 23.


Quality of life among symptomatic compared to PSA-detected prostate cancer survivors - results from a UK wide patient-reported outcomes study.

Donnelly DW, Vis LC, Kearney T, Sharp L, Bennett D, Wilding S, Downing A, Wright P, Watson E, Wagland R, Cross WR, Mason MD, Siesling S, van Manen JG, Glaser AW, Gavin A.

BMC Cancer. 2019 Oct 15;19(1):947. doi: 10.1186/s12885-019-6164-5.


Identification of metabolites from tandem mass spectra with a machine learning approach utilizing structural features.

Li Y, Kuhn M, Gavin AC, Bork P.

Bioinformatics. 2019 Oct 12. pii: btz736. doi: 10.1093/bioinformatics/btz736. [Epub ahead of print]


Maternal Education in Early Life and Risk of Metabolic Syndrome in Young Adult American Females and Males: Disentangling Life Course Processes Through Causal Models.

Huang JY, Gariépy G, Gavin AR, Rowhani-Rahbar A, Siscovick DS, Enquobahrie DA.

Epidemiology. 2019 Nov;30 Suppl 2:S28-S36. doi: 10.1097/EDE.0000000000001068.


Progress in cancer survival, mortality, and incidence in seven high-income countries 1995-2014 (ICBP SURVMARK-2): a population-based study.

Arnold M, Rutherford MJ, Bardot A, Ferlay J, Andersson TM, Myklebust TÅ, Tervonen H, Thursfield V, Ransom D, Shack L, Woods RR, Turner D, Leonfellner S, Ryan S, Saint-Jacques N, De P, McClure C, Ramanakumar AV, Stuart-Panko H, Engholm G, Walsh PM, Jackson C, Vernon S, Morgan E, Gavin A, Morrison DS, Huws DW, Porter G, Butler J, Bryant H, Currow DC, Hiom S, Parkin DM, Sasieni P, Lambert PC, Møller B, Soerjomataram I, Bray F.

Lancet Oncol. 2019 Nov;20(11):1493-1505. doi: 10.1016/S1470-2045(19)30456-5. Epub 2019 Sep 11.


Prognosis following surgical resection versus local excision of stage pT1 colorectal cancer: A population-based cohort study.

McBride R, Hicks BM, Coleman HG, Loughrey MB, Gavin AT, Dunne PD, Campbell WJ.

Surgeon. 2019 Aug 8. pii: S1479-666X(19)30084-8. doi: 10.1016/j.surge.2019.06.004. [Epub ahead of print]


Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells.

Sinha RK, Flynn R, Zaiken M, Paz K, Gavin AL, Nemazee D, Fernández JA, Xu X, Griffin JH, Blazar BR.

Blood. 2019 Aug 29;134(9):776-781. doi: 10.1182/blood.2019001259. Epub 2019 Jun 26.


Predictors of an early death in patients diagnosed with colon cancer: a retrospective case-control study in the UK.

Donnelly C, Hart N, McCrorie AD, Donnelly M, Anderson L, Ranaghan L, Gavin A.

BMJ Open. 2019 Jun 19;9(6):e026057. doi: 10.1136/bmjopen-2018-026057.


Prevalence of antenatal suicidal ideation among racially and ethnically diverse WIC enrolled women receiving care in a Midwestern public health clinic.

Tabb KM, Gavin AR, Faisal-Cury A, Nidey N, Chan YF, Malinga T, Meline B, Huang H.

J Affect Disord. 2019 Sep 1;256:278-281. doi: 10.1016/j.jad.2019.06.012. Epub 2019 Jun 4.


Payment Innovations to Drive Improvements in Pediatric Care-The Integrated Care for Kids Model.

Alley DE, Ashford NC, Gavin AM.

JAMA Pediatr. 2019 Jun 3. doi: 10.1001/jamapediatrics.2019.1703. [Epub ahead of print] No abstract available.


The psychological impact of being on a monitoring pathway for localised prostate cancer: A UK-wide mixed methods study.

Matheson L, Wilding S, Wagland R, Nayoan J, Rivas C, Downing A, Wright P, Brett J, Kearney T, Cross W, Glaser A, Gavin A, Watson E.

Psychooncology. 2019 Jul;28(7):1567-1575. doi: 10.1002/pon.5133. Epub 2019 Jun 10.


Cancer-related symptoms, mental well-being, and psychological distress in men diagnosed with prostate cancer treated with androgen deprivation therapy.

Wilding S, Downing A, Wright P, Selby P, Watson E, Wagland R, Donnelly DW, Hounsome L, Butcher H, Mason M, Henry A, Gavin A, Glaser AW.

Qual Life Res. 2019 Oct;28(10):2741-2751. doi: 10.1007/s11136-019-02212-x. Epub 2019 May 21.


Key factors associated with social distress after prostate cancer: Results from the United Kingdom Life after Prostate Cancer diagnosis study.

Wright P, Wilding S, Watson E, Downing A, Selby P, Hounsome L, Wagland R, Brewster DH, Huws D, Butcher H, Mottram R, Kearney T, Allen M, Gavin A, Glaser A.

Cancer Epidemiol. 2019 Jun;60:201-207. doi: 10.1016/j.canep.2019.04.006. Epub 2019 May 6.


Regional Variations in Quality of Survival Among Men with Prostate Cancer Across the United Kingdom.

Donnelly DW, Gavin A, Downing A, Hounsome L, Kearney T, McNair E, Allan D, Huws DW, Wright P, Selby PJ, Kind P, Watson E, Wagland R, Wilding S, Butcher H, Mottram R, Allen M, McSorley O, Sharp L, Mason MD, Cross WR, Catto JWF, Glaser AW.

Eur Urol. 2019 Aug;76(2):228-237. doi: 10.1016/j.eururo.2019.04.018. Epub 2019 May 4.


Outcomes of patients with heart failure after primary prevention ICD unit generator replacement.

Looi KL, Gavin A, Cooper L, Dawson L, Slipper D, Lever N.

Heart Asia. 2019 Feb 28;11(1):e011162. doi: 10.1136/heartasia-2018-011162. eCollection 2019.


Systematic Evaluation of Patient-Reported Outcome Protocol Content and Reporting in Cancer Trials.

Kyte D, Retzer A, Ahmed K, Keeley T, Armes J, Brown JM, Calman L, Gavin A, Glaser AW, Greenfield DM, Lanceley A, Taylor RM, Velikova G, Brundage M, Efficace F, Mercieca-Bebber R, King MT, Turner G, Calvert M.

J Natl Cancer Inst. 2019 Nov 1;111(11):1170-1178. doi: 10.1093/jnci/djz038.


External validation of a model to determine risk of progression of Barrett's oesophagus to neoplasia.

Kunzmann AT, Thrift AP, Johnston BT, McManus DT, Gavin AT, Turkington RC, Coleman HG.

Aliment Pharmacol Ther. 2019 May;49(10):1274-1281. doi: 10.1111/apt.15235. Epub 2019 Apr 4.


Utilization of cardiac resynchronization therapy in patients with heart failure in the Northern Region of New Zealand.

Looi KL, Gavin A, Sidhu K, Cooper L, Dawson L, Slipper D, Lever N.

J Arrhythm. 2018 Nov 2;35(1):52-60. doi: 10.1002/joa3.12134. eCollection 2019 Feb.


Quality of life in men living with advanced and localised prostate cancer in the UK: a population-based study.

Downing A, Wright P, Hounsome L, Selby P, Wilding S, Watson E, Wagland R, Kind P, Donnelly DW, Butcher H, Catto JWF, Cross W, Mason M, Sharp L, Weller D, Velikova G, McCaughan E, Mottram R, Allen M, Kearney T, McSorley O, Huws DW, Brewster DH, McNair E, Gavin A, Glaser AW.

Lancet Oncol. 2019 Mar;20(3):436-447. doi: 10.1016/S1470-2045(18)30780-0. Epub 2019 Jan 31.


MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas.

Maertens O, Kuzmickas R, Manchester HE, Emerson CE, Gavin AG, Guild CJ, Wong TC, De Raedt T, Bowman-Colin C, Hatchi E, Garraway LA, Flaherty KT, Pathania S, Elledge SJ, Cichowski K.

Cancer Discov. 2019 Apr;9(4):526-545. doi: 10.1158/2159-8290.CD-18-0879. Epub 2019 Feb 1.


Impact of variation in cancer registration practice on observed international cancer survival differences between International Cancer Benchmarking Partnership (ICBP) jurisdictions.

Eden M, Harrison S, Griffin M, Lambe M, Pettersson D, Gavin A, Brewster DH, Lin Y, Johannesen TB, Milne RL, Farrugia H, Nishri D, King MJ, Huws DW, Warlow J, Turner D, Earle CC, Peake M, Rashbass J.

Cancer Epidemiol. 2019 Feb;58:184-192. doi: 10.1016/j.canep.2018.10.019. Epub 2019 Jan 9.


Problems sleeping with prostate cancer: exploring possible risk factors for sleep disturbance in a population-based sample of survivors.

Maguire R, Drummond FJ, Hanly P, Gavin A, Sharp L.

Support Care Cancer. 2019 Sep;27(9):3365-3373. doi: 10.1007/s00520-018-4633-z. Epub 2019 Jan 9.


Reproducibility and reliability of retinal and optic disc measurements obtained with swept-source optical coherence tomography in a healthy population.

Satue M, Gavin A, Orduna E, Vilades E, Rodrigo MJ, Obis J, Polo V, Larrosa JM, Pablo LE, Garcia-Martin E.

Jpn J Ophthalmol. 2019 Mar;63(2):165-171. doi: 10.1007/s10384-018-00647-2. Epub 2019 Jan 2.


'Very difficult for an ordinary guy': Factors influencing the quality of treatment decision-making amongst men diagnosed with localised and locally advanced prostate cancer: Findings from a UK-wide mixed methods study.

Wagland R, Nayoan J, Matheson L, Rivas C, Brett J, Downing A, Wilding S, Butcher H, Gavin A, Glaser AW, Watson E.

Patient Educ Couns. 2019 Apr;102(4):797-803. doi: 10.1016/j.pec.2018.12.004. Epub 2018 Dec 3.


Diagnostic routes and time intervals for patients with colorectal cancer in 10 international jurisdictions; findings from a cross-sectional study from the International Cancer Benchmarking Partnership (ICBP).

Weller D, Menon U, Zalounina Falborg A, Jensen H, Barisic A, Knudsen AK, Bergin RJ, Brewster DH, Cairnduff V, Gavin AT, Grunfeld E, Harland E, Lambe M, Law RJ, Lin Y, Malmberg M, Turner D, Neal RD, White V, Harrison S, Reguilon I; ICBP Module 4 Working Group, Vedsted P.

BMJ Open. 2018 Nov 27;8(11):e023870. doi: 10.1136/bmjopen-2018-023870.


Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway.

Boulter E, Estrach S, Tissot FS, Hennrich ML, Tosello L, Cailleteau L, de la Ballina LR, Pisano S, Gavin AC, Féral CC.

Nat Commun. 2018 Nov 19;9(1):4862. doi: 10.1038/s41467-018-07268-w.


The challenges on the family unit faced by younger couples affected by prostate cancer: A qualitative study.

Collaço N, Wagland R, Alexis O, Gavin A, Glaser A, Watson EK.

Psychooncology. 2019 Feb;28(2):329-335. doi: 10.1002/pon.4944. Epub 2018 Dec 3.


Ability of swept source OCT to detect retinal changes in patients with bipolar disorder.

Polo V, Satue M, Gavin A, Vilades E, Orduna E, Cipres M, Garcia-Campayo J, Navarro-Gil M, Larrosa JM, Pablo LE, Garcia-Martin E.

Eye (Lond). 2019 Apr;33(4):549-556. doi: 10.1038/s41433-018-0261-6. Epub 2018 Oct 31.


Early Changes in Visual Quality and Corneal Structure after DMEK: Does DMEK Approach Optical Quality of a Healthy Cornea?

Satue M, Idoipe M, Gavin A, Romero-Sanz M, Liarakos VS, Mateo A, Garcia-Martin E, Blasco-Martinez A, Sanchez-Perez A.

J Ophthalmol. 2018 Sep 23;2018:2012560. doi: 10.1155/2018/2012560. eCollection 2018.


Enzymatic complexes across scales.

Kastritis PL, Gavin AC.

Essays Biochem. 2018 Oct 26;62(4):501-514. doi: 10.1042/EBC20180008. Print 2018 Oct 26. Review.


PLD3 and spinocerebellar ataxia.

Gonzalez AC, Stroobants S, Reisdorf P, Gavin AL, Nemazee D, Schwudke D, D'Hooge R, Saftig P, Damme M.

Brain. 2018 Nov 1;141(11):e78. doi: 10.1093/brain/awy258. No abstract available.


Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline.

Hennrich ML, Romanov N, Horn P, Jaeger S, Eckstein V, Steeples V, Ye F, Ding X, Poisa-Beiro L, Lai MC, Lang B, Boultwood J, Luft T, Zaugg JB, Pellagatti A, Bork P, Aloy P, Gavin AC, Ho AD.

Nat Commun. 2018 Oct 1;9(1):4004. doi: 10.1038/s41467-018-06353-4.


Treatment for erectile dysfunction among older men in Northern Ireland.

Donnelly DW, Kearney T, McCaughan E, Downing A, Weller D, Glaser AW, Gavin A.

Int J Clin Pract. 2019 Jan;73(1):e13259. doi: 10.1111/ijcp.13259. Epub 2018 Sep 17.


Effects of Acetylation and Phosphorylation on Subunit Interactions in Three Large Eukaryotic Complexes.

Šoštarić N, O'Reilly FJ, Giansanti P, Heck AJR, Gavin AC, van Noort V.

Mol Cell Proteomics. 2018 Dec;17(12):2387-2401. doi: 10.1074/mcp.RA118.000892. Epub 2018 Sep 4.


Racial Differences in Mechanisms Linking Childhood Socioeconomic Status With Growth in Adult Body Mass Index: The Role of Adolescent Risk and Educational Attainment.

Gavin AR, Jones TM, Kosterman R, Lee JO, Cambron C, Epstein M, Hill KG, Hawkins JD.

J Adolesc Health. 2018 Oct;63(4):474-481. doi: 10.1016/j.jadohealth.2018.05.015. Epub 2018 Aug 24.


PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.

Gavin AL, Huang D, Huber C, Mårtensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, Schulz SR, Zarpellon A, Cravatt B, Pang ES, Teijaro J, de la Torre JC, O'Keeffe M, Hochrein H, Damme M, Teyton L, Lawson BR, Nemazee D.

Nat Immunol. 2018 Sep;19(9):942-953. doi: 10.1038/s41590-018-0179-y. Epub 2018 Aug 13.


Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018.

Ferlay J, Colombet M, Soerjomataram I, Dyba T, Randi G, Bettio M, Gavin A, Visser O, Bray F.

Eur J Cancer. 2018 Nov;103:356-387. doi: 10.1016/j.ejca.2018.07.005. Epub 2018 Aug 9. Review.


Factors influencing job loss and early retirement in working men with prostate cancer-findings from the population-based Life After Prostate Cancer Diagnosis (LAPCD) study.

Bennett D, Kearney T, Donnelly DW, Downing A, Wright P, Wilding S, Wagland R, Watson E, Glaser A, Gavin A.

J Cancer Surviv. 2018 Oct;12(5):669-678. doi: 10.1007/s11764-018-0704-x. Epub 2018 Jul 30.


Metabolomics Discovers Early-Response Metabolic Biomarkers that Can Predict Chronic Reproductive Fitness in Individual Daphnia magna.

Taylor NS, Gavin A, Viant MR.

Metabolites. 2018 Jul 23;8(3). pii: E42. doi: 10.3390/metabo8030042.



Garcia-Martin E, Gavin A, Garcia-Campayo J, Vilades E, Orduna E, Polo V, Larrosa JM, Pablo LE, Satue M.

Retina. 2019 Oct;39(10):2012-2021. doi: 10.1097/IAE.0000000000002252.


Defects in orthorhombic LaMnO3 - ionic versus electronic compensation.

Gavin AL, Watson GW.

Phys Chem Chem Phys. 2018 Jul 18;20(28):19257-19267. doi: 10.1039/c8cp02763c.


Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations.

Pellagatti A, Armstrong RN, Steeples V, Sharma E, Repapi E, Singh S, Sanchi A, Radujkovic A, Horn P, Dolatshad H, Roy S, Broxholme J, Lockstone H, Taylor S, Giagounidis A, Vyas P, Schuh A, Hamblin A, Papaemmanuil E, Killick S, Malcovati L, Hennrich ML, Gavin AC, Ho AD, Luft T, Hellström-Lindberg E, Cazzola M, Smith CWJ, Smith S, Boultwood J.

Blood. 2018 Sep 20;132(12):1225-1240. doi: 10.1182/blood-2018-04-843771. Epub 2018 Jun 21.

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