Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 43

1.

4,5-Diaryl 3(2H)Furanones: Anti-Inflammatory Activity and Influence on Cancer Growth.

Semenok D, Medvedev J, Giassafaki LP, Lavdas I, Vizirianakis IS, Eleftheriou P, Gavalas A, Petrou A, Geronikaki A.

Molecules. 2019 May 6;24(9). pii: E1751. doi: 10.3390/molecules24091751.

2.

Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression.

Giannios I, Serafimidis I, Anastasiou V, Pezzolla D, Lesche M, Andree C, Bickle M, Gavalas A.

Stem Cells. 2019 May;37(5):640-651. doi: 10.1002/stem.2979. Epub 2019 Feb 13.

PMID:
30681750
3.

Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.

Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A.

PLoS Biol. 2017 Mar 1;15(3):e2000949. doi: 10.1371/journal.pbio.2000949. eCollection 2017 Mar.

4.

Outbreak of Extended-Spectrum Beta-Lactamase Producing Enterobacter cloacae with High MICs of Quaternary Ammonium Compounds in a Hematology Ward Associated with Contaminated Sinks.

Chapuis A, Amoureux L, Bador J, Gavalas A, Siebor E, Chrétien ML, Caillot D, Janin M, de Curraize C, Neuwirth C.

Front Microbiol. 2016 Jul 12;7:1070. doi: 10.3389/fmicb.2016.01070. eCollection 2016.

5.

Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.

Theodosis-Nobelos P, Kourti M, Gavalas A, Rekka EA.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):910-913. doi: 10.1016/j.bmcl.2015.12.063. Epub 2015 Dec 19.

PMID:
26750253
6.

Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice.

Anastasiou V, Ninou E, Alexopoulou D, Stertmann J, Müller A, Dahl A, Solimena M, Speier S, Serafimidis I, Gavalas A.

Diabetologia. 2016 Jan;59(1):139-150. doi: 10.1007/s00125-015-3784-4. Epub 2015 Oct 31.

7.

Potent, orally available, selective COX-2 inhibitors based on 2-imidazoline core.

Sarnpitak P, Mujumdar P, Morisseau C, Hwang SH, Hammock B, Iurchenko V, Zozulya S, Gavalas A, Geronikaki A, Ivanenkov Y, Krasavin M.

Eur J Med Chem. 2014 Sep 12;84:160-72. doi: 10.1016/j.ejmech.2014.07.023. Epub 2014 Jul 8.

PMID:
25016374
8.

Segregation of family A G protein-coupled receptor protomers in the plasma membrane.

Gavalas A, Lan TH, Liu Q, Corrêa IR Jr, Javitch JA, Lambert NA.

Mol Pharmacol. 2013 Sep;84(3):346-52. doi: 10.1124/mol.113.086868. Epub 2013 Jun 18.

9.

Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents.

Apostolidis I, Liaras K, Geronikaki A, Hadjipavlou-Litina D, Gavalas A, Soković M, Glamočlija J, Ćirić A.

Bioorg Med Chem. 2013 Jan 15;21(2):532-9. doi: 10.1016/j.bmc.2012.10.046. Epub 2012 Nov 17.

PMID:
23219856
10.

ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools.

Ioannou M, Serafimidis I, Arnes L, Sussel L, Singh S, Vasiliou V, Gavalas A.

Dev Biol. 2013 Feb 1;374(1):153-63. doi: 10.1016/j.ydbio.2012.10.030. Epub 2012 Nov 6.

11.

G protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesis.

Serafimidis I, Heximer S, Beis D, Gavalas A.

Mol Cell Biol. 2011 Nov;31(22):4442-53. doi: 10.1128/MCB.05702-11. Epub 2011 Sep 12.

12.

Directed neural differentiation of mouse embryonic stem cells is a sensitive system for the identification of novel Hox gene effectors.

Bami M, Episkopou V, Gavalas A, Gouti M.

PLoS One. 2011;6(5):e20197. doi: 10.1371/journal.pone.0020197. Epub 2011 May 26.

13.

Anterior Hox genes interact with components of the neural crest specification network to induce neural crest fates.

Gouti M, Briscoe J, Gavalas A.

Stem Cells. 2011 May;29(5):858-70. doi: 10.1002/stem.630.

14.

Development of a chromosomally integrated metabolite-inducible Leu3p-alpha-IPM "off-on" gene switch.

Poulou M, Bell D, Bozonelos K, Alexiou M, Gavalas A, Lovell-Badge R, Remboutsika E.

PLoS One. 2010 Aug 31;5(8):e12488. doi: 10.1371/journal.pone.0012488.

15.

Identification of phylogenetically conserved enhancer elements implicated in pancreas development in the WISP1 and CTGF orthologs.

Kapasa M, Serafimidis I, Gavalas A, Kossida S.

Genomics. 2008 Nov;92(5):301-8. doi: 10.1016/j.ygeno.2008.06.003. Epub 2008 Aug 28.

16.

Hoxb1 controls cell fate specification and proliferative capacity of neural stem and progenitor cells.

Gouti M, Gavalas A.

Stem Cells. 2008 Aug;26(8):1985-97. doi: 10.1634/stemcells.2008-0182. Epub 2008 May 22.

17.

Inhibition of renin-angiotensin system and advanced glycation end products formation: a promising therapeutic approach targeting on cardiovascular diseases.

Geronikaki A, Gavalas A, Dislian V, Giannoglou G.

Cardiovasc Hematol Agents Med Chem. 2007 Oct;5(4):249-64. Review.

PMID:
17979687
18.

Novel effectors of directed and Ngn3-mediated differentiation of mouse embryonic stem cells into endocrine pancreas progenitors.

Serafimidis I, Rakatzi I, Episkopou V, Gouti M, Gavalas A.

Stem Cells. 2008 Jan;26(1):3-16. Epub 2007 Oct 11.

19.

Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis.

Jacob J, Ferri AL, Milton C, Prin F, Pla P, Lin W, Gavalas A, Ang SL, Briscoe J.

Nat Neurosci. 2007 Nov;10(11):1433-9. Epub 2007 Oct 7.

PMID:
17922007
20.

Antioxidants and inflammatory disease: synthetic and natural antioxidants with anti-inflammatory activity.

Geronikaki AA, Gavalas AM.

Comb Chem High Throughput Screen. 2006 Jul;9(6):425-42. Review.

PMID:
16842224
21.

New analogues of butylated hydroxytoluene as anti-inflammatory and antioxidant agents.

Ziakas GN, Rekka EA, Gavalas AM, Eleftheriou PT, Kourounakis PN.

Bioorg Med Chem. 2006 Aug 15;14(16):5616-24. Epub 2006 May 11.

PMID:
16690318
22.

Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties.

Doulgkeris CM, Galanakis D, Kourounakis AP, Tsiakitzis KC, Gavalas AM, Eleftheriou PT, Victoratos P, Rekka EA, Kourounakis PN.

Bioorg Med Chem Lett. 2006 Feb 15;16(4):825-9. Epub 2005 Nov 23.

PMID:
16309906
23.

Nitric oxide releasing derivatives of tolfenamic acid with anti-inflammatory activity and safe gastrointestinal profile.

Ziakas GN, Rekka EA, Gavalas AM, Eleftheriou PT, Tsiakitzis KC, Kourounakis PN.

Bioorg Med Chem. 2005 Dec 1;13(23):6485-92. Epub 2005 Sep 26.

PMID:
16185877
24.

Loss of function but no gain of function caused by amino acid substitutions in the hexapeptide of Hoxa1 in vivo.

Remacle S, Abbas L, De Backer O, Pacico N, Gavalas A, Gofflot F, Picard JJ, Rezsöhazy R.

Mol Cell Biol. 2004 Oct;24(19):8567-75.

25.

Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.

Galanakis D, Kourounakis AP, Tsiakitzis KC, Doulgkeris C, Rekka EA, Gavalas A, Kravaritou C, Charitos C, Kourounakis PN.

Bioorg Med Chem Lett. 2004 Jul 16;14(14):3639-43.

PMID:
15203134
26.

Behavioral and antioxidant activity of a tosylbenz[g]indolamine derivative. A proposed better profile for a potential antipsychotic agent.

Zika CA, Nicolaou I, Gavalas A, Rekatas GV, Tani E, Demopoulos VJ.

Ann Gen Hosp Psychiatry. 2004 Jan 7;3(1):1.

27.

Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes.

Gavalas A, Ruhrberg C, Livet J, Henderson CE, Krumlauf R.

Development. 2003 Dec;130(23):5663-79. Epub 2003 Oct 1.

28.

Alkannin and shikonin: effect on free radical processes and on inflammation - a preliminary pharmacochemical investigation.

Kourounakis AP, Assimopoulou AN, Papageorgiou VP, Gavalas A, Kourounakis PN.

Arch Pharm (Weinheim). 2002 Jun;335(6):262-6.

PMID:
12210768
29.

ArRAnging the hindbrain.

Gavalas A.

Trends Neurosci. 2002 Feb;25(2):61-4. Review.

PMID:
11814548
30.

Synergy between Hoxa1 and Hoxb1: the relationship between arch patterning and the generation of cranial neural crest.

Gavalas A, Trainor P, Ariza-McNaughton L, Krumlauf R.

Development. 2001 Aug;128(15):3017-27.

31.

The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function.

Di Rocco G, Gavalas A, Popperl H, Krumlauf R, Mavilio F, Zappavigna V.

J Biol Chem. 2001 Jun 8;276(23):20506-15. Epub 2001 Mar 1.

32.

Retinoid signalling and hindbrain patterning.

Gavalas A, Krumlauf R.

Curr Opin Genet Dev. 2000 Aug;10(4):380-6. Review.

PMID:
10889064
33.
34.

Segmentation and specification in the branchial region of the head: the role of the Hox selector genes.

Rijli FM, Gavalas A, Chambon P.

Int J Dev Biol. 1998;42(3):393-401. Review.

35.

Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch.

Gavalas A, Studer M, Lumsden A, Rijli FM, Krumlauf R, Chambon P.

Development. 1998 Mar;125(6):1123-36.

36.

Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning.

Studer M, Gavalas A, Marshall H, Ariza-McNaughton L, Rijli FM, Chambon P, Krumlauf R.

Development. 1998 Mar;125(6):1025-36.

37.

Role of Hoxa-2 in axon pathfinding and rostral hindbrain patterning.

Gavalas A, Davenne M, Lumsden A, Chambon P, Rijli FM.

Development. 1997 Oct;124(19):3693-702.

38.
39.

Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed.

Brayton KA, Chen Z, Zhou G, Nagy PL, Gavalas A, Trent JM, Deaven LL, Dixon JE, Zalkin H.

J Biol Chem. 1994 Feb 18;269(7):5313-21.

40.

The anti-inflammatory effect of opioids.

Gavalas A, Victoratos P, Yiangou M, Hadjipetrou-Kourounakis L, Rekka E, Kourounakis P.

Int J Neurosci. 1994 Jan-Feb;74(1-4):259-64.

PMID:
7928110
41.

Coexpression of two closely linked avian genes for purine nucleotide synthesis from a bidirectional promoter.

Gavalas A, Dixon JE, Brayton KA, Zalkin H.

Mol Cell Biol. 1993 Aug;13(8):4784-92. Erratum in: Mol Cell Biol 1993 Dec;13(12):7977.

42.
43.

Supplemental Content

Loading ...
Support Center