Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 210

1.

Mendelian Randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures.

Zheng J, Maerz W, Gergei I, Kleber M, Drechsler C, Wanner C, Brandenburg V, Reppe S, Gautvik KM, Medina-Gomez C, Shevroja E, Gilly A, Park YC, Dedoussis G, Zeggini E, Lorentzon M, Henning P, Lerner UH, Nilsson K, Movérare-Skrtic S, Baird D, Elsworth B, Falk L, Groom A, Capellini TD, Grundberg E, Nethander M, Ohlsson C, Smith GD, Tobias JH.

J Bone Miner Res. 2019 Jun 6. doi: 10.1002/jbmr.3803. [Epub ahead of print]

PMID:
31170332
2.

Genetic Polymorphism of miR-196a-2 is Associated with Bone Mineral Density (BMD).

Karabegović I, Maas S, Medina-Gomez C, Zrimšek M, Reppe S, Gautvik KM, Uitterlinden AG, Rivadeneira F, Ghanbari M.

Int J Mol Sci. 2017 Nov 25;18(12). pii: E2529. doi: 10.3390/ijms18122529.

3.

Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density.

Alonso N, Estrada K, Albagha OME, Herrera L, Reppe S, Olstad OK, Gautvik KM, Ryan NM, Evans KL, Nielson CM, Hsu YH, Kiel DP, Markozannes G, Ntzani EE, Evangelou E, Feenstra B, Liu X, Melbye M, Masi L, Brandi ML, Riches P, Daroszewska A, Olmos JM, Valero C, Castillo J, Riancho JA, Husted LB, Langdahl BL, Brown MA, Duncan EL, Kaptoge S, Khaw KT, Usategui-Martín R, Del Pino-Montes J, González-Sarmiento R, Lewis JR, Prince RL, D'Amelio P, García-Giralt N, Nogués X, Mencej-Bedrac S, Marc J, Wolstein O, Eisman JA, Oei L, Medina-Gómez C, Schraut KE, Navarro P, Wilson JF, Davies G, Starr J, Deary I, Tanaka T, Ferrucci L, Gianfrancesco F, Gennari L, Lucas G, Elosua R, Uitterlinden AG, Rivadeneira F, Ralston SH.

Ann Rheum Dis. 2018 Mar;77(3):378-385. doi: 10.1136/annrheumdis-2017-212469. Epub 2017 Nov 23.

4.

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.

Medina-Gomez C, Kemp JP, Dimou NL, Kreiner E, Chesi A, Zemel BS, Bønnelykke K, Boer CG, Ahluwalia TS, Bisgaard H, Evangelou E, Heppe DHM, Bonewald LF, Gorski JP, Ghanbari M, Demissie S, Duque G, Maurano MT, Kiel DP, Hsu YH, C J van der Eerden B, Ackert-Bicknell C, Reppe S, Gautvik KM, Raastad T, Karasik D, van de Peppel J, Jaddoe VWV, Uitterlinden AG, Tobias JH, Grant SFA, Bagos PG, Evans DM, Rivadeneira F.

Nat Commun. 2017 Jul 25;8(1):121. doi: 10.1038/s41467-017-00108-3.

5.

Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women.

Reppe S, Lien TG, Hsu YH, Gautvik VT, Olstad OK, Yu R, Bakke HG, Lyle R, Kringen MK, Glad IK, Gautvik KM.

Epigenetics. 2017 Aug;12(8):674-687. doi: 10.1080/15592294.2017.1345832. Epub 2017 Jun 26.

6.

Omics analysis of human bone to identify genes and molecular networks regulating skeletal remodeling in health and disease.

Reppe S, Datta HK, Gautvik KM.

Bone. 2017 Aug;101:88-95. doi: 10.1016/j.bone.2017.04.012. Epub 2017 Apr 24. Review.

PMID:
28450214
7.

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

Nielson CM, Liu CT, Smith AV, Ackert-Bicknell CL, Reppe S, Jakobsdottir J, Wassel C, Register TC, Oei L, Alonso N, Oei EH, Parimi N, Samelson EJ, Nalls MA, Zmuda J, Lang T, Bouxsein M, Latourelle J, Claussnitzer M, Siggeirsdottir K, Srikanth P, Lorentzen E, Vandenput L, Langefeld C, Raffield L, Terry G, Cox AJ, Allison MA, Criqui MH, Bowden D, Ikram MA, Mellström D, Karlsson MK, Carr J, Budoff M, Phillips C, Cupples LA, Chou WC, Myers RH, Ralston SH, Gautvik KM, Cawthon PM, Cummings S, Karasik D, Rivadeneira F, Gudnason V, Orwoll ES, Harris TB, Ohlsson C, Kiel DP, Hsu YH.

J Bone Miner Res. 2016 Dec;31(12):2085-2097. doi: 10.1002/jbmr.2913. Epub 2016 Sep 6.

8.

The Influence of DNA Methylation on Bone Cells.

Reppe S, Datta H, Gautvik KM.

Curr Genomics. 2015 Dec;16(6):384-92. doi: 10.2174/1389202916666150817202913.

9.

Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci.

Reppe S, Wang Y, Thompson WK, McEvoy LK, Schork AJ, Zuber V, LeBlanc M, Bettella F, Mills IG, Desikan RS, Djurovic S, Gautvik KM, Dale AM, Andreassen OA; GEFOS Consortium.

PLoS One. 2015 Dec 22;10(12):e0144531. doi: 10.1371/journal.pone.0144531. eCollection 2015.

10.

Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors.

LeBlanc M, Zuber V, Andreassen BK, Witoelar A, Zeng L, Bettella F, Wang Y, McEvoy LK, Thompson WK, Schork AJ, Reppe S, Barrett-Connor E, Ligthart S, Dehghan A, Gautvik KM, Nelson CP, Schunkert H, Samani NJ; CARDIoGRAM Consortium, Ridker PM, Chasman DI, Aukrust P, Djurovic S, Frigessi A, Desikan RS, Dale AM, Andreassen OA.

Circ Res. 2016 Jan 8;118(1):83-94. doi: 10.1161/CIRCRESAHA.115.306629. Epub 2015 Oct 20.

11.

The α2β1 binding domain of chondroadherin inhibits breast cancer-induced bone metastases and impairs primary tumour growth: a preclinical study.

Rucci N, Capulli M, Olstad OK, Önnerfjord P, Tillgren V, Gautvik KM, Heinegård D, Teti A.

Cancer Lett. 2015 Mar 1;358(1):67-75. doi: 10.1016/j.canlet.2014.12.032. Epub 2014 Dec 18.

PMID:
25529009
12.

What happens in the brain in narcolepsy over time?

Heier MS, Gautvik KM.

Sleep Med. 2014 Nov;15(11):1427. doi: 10.1016/j.sleep.2014.07.003. Epub 2014 Jul 8. No abstract available.

PMID:
25194584
13.

Methylation of bone SOST, its mRNA, and serum sclerostin levels correlate strongly with fracture risk in postmenopausal women.

Reppe S, Noer A, Grimholt RM, Halldórsson BV, Medina-Gomez C, Gautvik VT, Olstad OK, Berg JP, Datta H, Estrada K, Hofman A, Uitterlinden AG, Rivadeneira F, Lyle R, Collas P, Gautvik KM.

J Bone Miner Res. 2015 Feb;30(2):249-56. doi: 10.1002/jbmr.2342.

14.

Increased cerebrospinal fluid levels of nerve cell biomarkers in narcolepsy with cataplexy.

Heier MS, Skinningsrud A, Paus E, Gautvik KM.

Sleep Med. 2014 Jun;15(6):614-8. doi: 10.1016/j.sleep.2014.02.005. Epub 2014 Apr 1.

PMID:
24784789
15.

The C-terminal domain of chondroadherin: a new regulator of osteoclast motility counteracting bone loss.

Capulli M, Olstad OK, Onnerfjord P, Tillgren V, Muraca M, Gautvik KM, Heinegård D, Rucci N, Teti A.

J Bone Miner Res. 2014 Aug;29(8):1833-46. doi: 10.1002/jbmr.2206.

16.

Global miRNA expression analysis of serous and clear cell ovarian carcinomas identifies differentially expressed miRNAs including miR-200c-3p as a prognostic marker.

Vilming Elgaaen B, Olstad OK, Haug KB, Brusletto B, Sandvik L, Staff AC, Gautvik KM, Davidson B.

BMC Cancer. 2014 Feb 11;14:80. doi: 10.1186/1471-2407-14-80.

17.

Transcriptional profiling of mRNAs and microRNAs in human bone marrow precursor B cells identifies subset- and age-specific variations.

Jensen K, Brusletto BS, Aass HC, Olstad OK, Kierulf P, Gautvik KM.

PLoS One. 2013 Jul 30;8(7):e70721. doi: 10.1371/journal.pone.0070721. Print 2013.

18.

Increased ID2 levels in adult precursor B cells as compared with children is associated with impaired Ig locus contraction and decreased bone marrow output.

Jensen K, Rother MB, Brusletto BS, Olstad OK, Dalsbotten Aass HC, van Zelm MC, Kierulf P, Gautvik KM.

J Immunol. 2013 Aug 1;191(3):1210-9. doi: 10.4049/jimmunol.1203462. Epub 2013 Jul 3.

19.

Incidence of narcolepsy in Norwegian children and adolescents after vaccination against H1N1 influenza A.

Heier MS, Gautvik KM, Wannag E, Bronder KH, Midtlyng E, Kamaleri Y, Storsaeter J.

Sleep Med. 2013 Sep;14(9):867-71. doi: 10.1016/j.sleep.2013.03.020. Epub 2013 Jun 14.

PMID:
23773727
20.

Identification of transcriptional macromolecular associations in human bone using browser based in silico analysis in a giant correlation matrix.

Reppe S, Sachse D, Olstad OK, Gautvik VT, Sanderson P, Datta HK, Berg JP, Gautvik KM.

Bone. 2013 Mar;53(1):69-78. doi: 10.1016/j.bone.2012.11.015. Epub 2012 Nov 27.

PMID:
23195995
21.

ZNF385B and VEGFA are strongly differentially expressed in serous ovarian carcinomas and correlate with survival.

Elgaaen BV, Olstad OK, Sandvik L, Odegaard E, Sauer T, Staff AC, Gautvik KM.

PLoS One. 2012;7(9):e46317. doi: 10.1371/journal.pone.0046317. Epub 2012 Sep 28.

22.

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus.

Medina-Gomez C, Kemp JP, Estrada K, Eriksson J, Liu J, Reppe S, Evans DM, Heppe DH, Vandenput L, Herrera L, Ring SM, Kruithof CJ, Timpson NJ, Zillikens MC, Olstad OK, Zheng HF, Richards JB, St Pourcain B, Hofman A, Jaddoe VW, Smith GD, Lorentzon M, Gautvik KM, Uitterlinden AG, Brommage R, Ohlsson C, Tobias JH, Rivadeneira F.

PLoS Genet. 2012 Jul;8(7):e1002718. doi: 10.1371/journal.pgen.1002718. Epub 2012 Jul 5.

23.

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, González-Macías J, Kähönen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren Ö, Lorenc RS, Marc J, Mellström D, Obermayer-Pietsch B, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Ridker PM, Rousseau F, Slagboom PE, Tang NL, Urreizti R, Van Hul W, Viikari J, Zarrabeitia MT, Aulchenko YS, Castano-Betancourt M, Grundberg E, Herrera L, Ingvarsson T, Johannsdottir H, Kwan T, Li R, Luben R, Medina-Gómez C, Palsson ST, Reppe S, Rotter JI, Sigurdsson G, van Meurs JB, Verlaan D, Williams FM, Wood AR, Zhou Y, Gautvik KM, Pastinen T, Raychaudhuri S, Cauley JA, Chasman DI, Clark GR, Cummings SR, Danoy P, Dennison EM, Eastell R, Eisman JA, Gudnason V, Hofman A, Jackson RD, Jones G, Jukema JW, Khaw KT, Lehtimäki T, Liu Y, Lorentzon M, McCloskey E, Mitchell BD, Nandakumar K, Nicholson GC, Oostra BA, Peacock M, Pols HA, Prince RL, Raitakari O, Reid IR, Robbins J, Sambrook PN, Sham PC, Shuldiner AR, Tylavsky FA, van Duijn CM, Wareham NJ, Cupples LA, Econs MJ, Evans DM, Harris TB, Kung AW, Psaty BM, Reeve J, Spector TD, Streeten EA, Zillikens MC, Thorsteinsdottir U, Ohlsson C, Karasik D, Richards JB, Brown MA, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F.

Nat Genet. 2012 Apr 15;44(5):491-501. doi: 10.1038/ng.2249.

24.

Cerebrospinal fluid hypocretin 1 deficiency, overweight, and metabolic dysregulation in patients with narcolepsy.

Heier MS, Jansson TS, Gautvik KM.

J Clin Sleep Med. 2011 Dec 15;7(6):653-8. doi: 10.5664/jcsm.1474.

25.

Molecular disease map of bone characterizing the postmenopausal osteoporosis phenotype.

Jemtland R, Holden M, Reppe S, Olstad OK, Reinholt FP, Gautvik VT, Refvem H, Frigessi A, Houston B, Gautvik KM.

J Bone Miner Res. 2011 Aug;26(8):1793-801. doi: 10.1002/jbmr.396.

26.

POLD2 and KSP37 (FGFBP2) correlate strongly with histology, stage and outcome in ovarian carcinomas.

Elgaaen BV, Haug KB, Wang J, Olstad OK, Fortunati D, Onsrud M, Staff AC, Sauer T, Gautvik KM.

PLoS One. 2010 Nov 4;5(11):e13837. doi: 10.1371/journal.pone.0013837.

27.

Periostin is a collagen associated bone matrix protein regulated by parathyroid hormone.

Fortunati D, Reppe S, Fjeldheim AK, Nielsen M, Gautvik VT, Gautvik KM.

Matrix Biol. 2010 Sep;29(7):594-601. doi: 10.1016/j.matbio.2010.07.001. Epub 2010 Jul 21.

PMID:
20654714
28.

Skeletal site-related variation in human trabecular bone transcriptome and signaling.

Varanasi SS, Olstad OK, Swan DC, Sanderson P, Gautvik VT, Reppe S, Francis RM, Gautvik KM, Datta HK.

PLoS One. 2010 May 18;5(5):e10692. doi: 10.1371/journal.pone.0010692.

29.

Zic1 transcription factor in bone: neural developmental protein regulates mechanotransduction in osteocytes.

Kalogeropoulos M, Varanasi SS, Olstad OK, Sanderson P, Gautvik VT, Reppe S, Francis RM, Gautvik KM, Birch MA, Datta HK.

FASEB J. 2010 Aug;24(8):2893-903. doi: 10.1096/fj.09-148908. Epub 2010 Mar 30.

PMID:
20354137
30.

Striking decrease in the total precursor B-cell compartment during early childhood as evidenced by flow cytometry and gene expression changes.

Jensen K, Schaffer L, Olstad OK, Bechensteen AG, Hellebostad M, Tjønnfjord GE, Kierulf P, Gautvik KM, Osnes LT.

Pediatr Hematol Oncol. 2010 Feb;27(1):31-45. doi: 10.3109/08880010903420687.

PMID:
20121553
31.

Eight genes are highly associated with BMD variation in postmenopausal Caucasian women.

Reppe S, Refvem H, Gautvik VT, Olstad OK, Høvring PI, Reinholt FP, Holden M, Frigessi A, Jemtland R, Gautvik KM.

Bone. 2010 Mar;46(3):604-12. doi: 10.1016/j.bone.2009.11.007. Epub 2009 Nov 14.

PMID:
19922823
32.

Calmodulin-dependent kinase 1beta is expressed in the epiphyseal growth plate and regulates proliferation of mouse calvarial osteoblasts in vitro.

Pedersen ME, Fortunati D, Nielsen M, Brorson SH, Lekva T, Nissen-Meyer LS, Gautvik VT, Shahdadfar A, Gautvik KM, Jemtland R.

Bone. 2008 Oct;43(4):700-7. doi: 10.1016/j.bone.2008.06.006. Epub 2008 Jun 20.

PMID:
18620088
33.

Osteopenia, decreased bone formation and impaired osteoblast development in Sox4 heterozygous mice.

Nissen-Meyer LS, Jemtland R, Gautvik VT, Pedersen ME, Paro R, Fortunati D, Pierroz DD, Stadelmann VA, Reppe S, Reinholt FP, Del Fattore A, Rucci N, Teti A, Ferrari S, Gautvik KM.

J Cell Sci. 2007 Aug 15;120(Pt 16):2785-95. Epub 2007 Jul 24.

34.

Abnormal muscle and hematopoietic gene expression may be important for clinical morbidity in primary hyperparathyroidism.

Reppe S, Stilgren L, Abrahamsen B, Olstad OK, Cero F, Brixen K, Nissen-Meyer LS, Gautvik KM.

Am J Physiol Endocrinol Metab. 2007 May;292(5):E1465-73. Epub 2007 Jan 16.

35.

The effect of enamel matrix derivative on gene expression in osteoblasts.

Reseland JE, Reppe S, Larsen AM, Berner HS, Reinholt FP, Gautvik KM, Slaby I, Lyngstadaas SP.

Eur J Oral Sci. 2006 May;114 Suppl 1:205-11; discussion 254-6, 381-2.

PMID:
16674687
36.

Gene expression profiles give insight into the molecular pathology of bone in primary hyperparathyroidism.

Reppe S, Stilgren L, Olstad OK, Brixen K, Nissen-Meyer LS, Gautvik KM, Abrahamsen B.

Bone. 2006 Jul;39(1):189-98. Epub 2006 Mar 3.

PMID:
16516570
37.

Thyrotrophin-releasing hormone receptor 1 and prothyrotrophin-releasing hormone mRNA expression in the central nervous system are regulated by suckling in lactating rats.

Fjeldheim AK, Høvring PI, Løseth OP, Johansen PW, Glover JC, Matre V, Olstad OK, Reppe S, Gordeladze JO, Walaas SI, Gautvik KM.

Eur J Endocrinol. 2005 May;152(5):791-803.

PMID:
15879366
38.

Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells.

Reppe S, Olstad OK, Rian E, Gautvik VT, Gautvik KM, Jemtland R.

Biochem Biophys Res Commun. 2004 Nov 5;324(1):218-23.

PMID:
15465005
39.

Molecular heterogeneity in human osteosarcoma demonstrated by enriched mRNAs isolated by directional tag PCR subtraction cloning.

Olstad OK, Gautvik VT, Reppe S, Rian E, Jemtland R, Ohlsson C, Bruland OS, Gautvik KM.

Anticancer Res. 2003 May-Jun;23(3B):2201-16.

PMID:
12894494
40.

The human neuroendocrine thyrotropin-releasing hormone receptor promoter is activated by the haematopoietic transcription factor c-Myb.

Matre V, Høvring PI, Fjeldheim AK, Helgeland L, Orvain C, Andersson KB, Gautvik KM, Gabrielsen OS.

Biochem J. 2003 Jun 15;372(Pt 3):851-9.

41.
42.
43.

Developmental regulation of two isoforms of Ca(2+)/calmodulin-dependent protein kinase I beta in rat brain.

Løseth OP, de Lecea L, Calbet M, Danielson PE, Gautvik V, Høvring PI, Walaas SI, Gautvik KM.

Brain Res. 2000 Jun 30;869(1-2):137-45.

PMID:
10865068
44.

Two human osteoblast-like osteosarcoma cell lines show distinct expression and differential regulation of parathyroid hormone-related protein.

Jemtland R, Rian E, Olstad OK, Haug E, Bruland OS, Bucht E, Gautvik KM.

J Bone Miner Res. 1999 Jun;14(6):904-14.

45.

Transcription of the human thyrotropin-releasing hormone receptor gene-analysis of basal promoter elements and glucocorticoid response elements.

Høvring PI, Matre V, Fjeldheim AK, Loseth OP, Gautvik KM.

Biochem Biophys Res Commun. 1999 Apr 21;257(3):829-34.

PMID:
10208868
46.

Structural and functional organization of the gene encoding the human thyrotropin-releasing hormone receptor.

Matre V, Høvring PI, Orstavik S, Frengen E, Rian E, Velickovic Z, Murray-McIntosh RP, Gautvik KM.

J Neurochem. 1999 Jan;72(1):40-50.

47.

[Medical research at Norwegian universities].

Røttingen JA, Thorsby P, Seem C, Gautvik KM.

Tidsskr Nor Laegeforen. 1998 Jun 10;118(15):2339-43. Norwegian.

PMID:
9691802
48.

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.

de Lecea L, Kilduff TS, Peyron C, Gao X, Foye PE, Danielson PE, Fukuhara C, Battenberg EL, Gautvik VT, Bartlett FS 2nd, Frankel WN, van den Pol AN, Bloom FE, Gautvik KM, Sutcliffe JG.

Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):322-7.

49.

Binding and cyclic AMP stimulation by N-terminally deleted human PTHs (3-84 and 4-84) in a homologous ligand receptor system.

Olstad OK, Reppe S, Loseth OP, Jemtland R, Gautvik KM.

J Bone Miner Res. 1997 Sep;12(9):1348-57.

50.

Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction.

Gautvik KM, de Lecea L, Gautvik VT, Danielson PE, Tranque P, Dopazo A, Bloom FE, Sutcliffe JG.

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8733-8.

Supplemental Content

Loading ...
Support Center