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Items: 1 to 50 of 88

1.

Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode.

Hedir S, De Giorgi M, Fogha J, De Pascale M, Weiswald LB, Brotin E, Marekha B, Denoyelle C, Denis C, Suzanne P, Gautier F, Juin P, Ligat L, Lopez F, Carlier L, Legay R, Bureau R, Rault S, Poulain L, Oliveira Santos JS, Voisin-Chiret AS.

Eur J Med Chem. 2018 Nov 5;159:357-380. doi: 10.1016/j.ejmech.2018.10.003. Epub 2018 Oct 4.

PMID:
30308410
2.

Repetitive somatic embryogenesis induced cytological and proteomic changes in embryogenic lines of Pseudotsuga menziesii [Mirb.].

Gautier F, Eliášová K, Leplé JC, Vondráková Z, Lomenech AM, Le Metté C, Label P, Costa G, Trontin JF, Teyssier C, Lelu-Walter MA.

BMC Plant Biol. 2018 Aug 10;18(1):164. doi: 10.1186/s12870-018-1337-y.

3.

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.

Aira LE, Villa E, Colosetti P, Gamas P, Signetti L, Obba S, Proics E, Gautier F, Bailly-Maitre B, Jacquel A, Robert G, Luciano F, Juin PP, Ricci JE, Auberger P, Marchetti S.

Oncogene. 2018 Apr;37(16):2122-2136. doi: 10.1038/s41388-017-0112-0. Epub 2018 Feb 2.

PMID:
29391601
4.

E2F1 interacts with BCL-xL and regulates its subcellular localization dynamics to trigger cell death.

Vuillier C, Lohard S, Fétiveau A, Allègre J, Kayaci C, King LE, Braun F, Barillé-Nion S, Gautier F, Dubrez L, Gilmore AP, Juin PP, Maillet L.

EMBO Rep. 2018 Feb;19(2):234-243. doi: 10.15252/embr.201744046. Epub 2017 Dec 12.

PMID:
29233828
5.

BCL-XL directly modulates RAS signalling to favour cancer cell stemness.

Carné Trécesson S, Souazé F, Basseville A, Bernard AC, Pécot J, Lopez J, Bessou M, Sarosiek KA, Letai A, Barillé-Nion S, Valo I, Coqueret O, Guette C, Campone M, Gautier F, Juin PP.

Nat Commun. 2017 Oct 24;8(1):1123. doi: 10.1038/s41467-017-01079-1.

6.

Integrated drought responses of black poplar: how important is phenotypic plasticity?

Garavillon-Tournayre M, Gousset-Dupont A, Gautier F, Benoit P, Conchon P, Souchal R, Lopez D, Petel G, Venisse JS, Bastien C, Label P, Fumanal B.

Physiol Plant. 2018 May;163(1):30-44. doi: 10.1111/ppl.12646. Epub 2017 Nov 13.

PMID:
28940533
7.

Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity.

Oizel K, Chauvin C, Oliver L, Gratas C, Geraldo F, Jarry U, Scotet E, Rabe M, Alves-Guerra MC, Teusan R, Gautier F, Loussouarn D, Compan V, Martinou JC, Vallette FM, Pecqueur C.

Clin Cancer Res. 2017 Oct 15;23(20):6292-6304. doi: 10.1158/1078-0432.CCR-16-3102. Epub 2017 Jul 18.

8.

Effect of foliar application of salicylic acid, hydrogen peroxide and a xyloglucan oligosaccharide on capsiate content and gene expression associatedwith capsinoids synthesis in Capsicum annuum L.

Zunun-Perez AY, Guevara-Figueroa T, Jimenez-Garcia SN, Feregrino-Perez AA, Gautier F, Guevara-Gonzalez RG.

J Biosci. 2017 Jun;42(2):245-250.

9.

Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3.

Atmanene C, Ronin C, Téletchéa S, Gautier FM, Djedaïni-Pilard F, Ciesielski F, Vivat V, Grandjean C.

Biochem Biophys Res Commun. 2017 Jul 29;489(3):281-286. doi: 10.1016/j.bbrc.2017.05.150. Epub 2017 May 26.

PMID:
28554839
10.

Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL.

Le Pen J, Maillet L, Sarosiek K, Vuillier C, Gautier F, Montessuit S, Martinou JC, Letaï A, Braun F, Juin PP.

Cell Death Dis. 2017 Feb 9;8(2):e2596. doi: 10.1038/cddis.2016.127. No abstract available.

11.

Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance.

Pécot J, Maillet L, Le Pen J, Vuillier C, Trécesson SC, Fétiveau A, Sarosiek KA, Bock FJ, Braun F, Letai A, Tait SWG, Gautier F, Juin PP.

Cell Rep. 2016 Dec 20;17(12):3347-3358. doi: 10.1016/j.celrep.2016.11.064.

12.

Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL.

Le Pen J, Maillet L, Sarosiek K, Vuillier C, Gautier F, Montessuit S, Martinou JC, Letaï A, Braun F, Juin PP.

Cell Death Dis. 2016 Feb 4;7:e2083. doi: 10.1038/cddis.2015.400. Erratum in: Cell Death Dis. 2017 Feb 9;8(2):e2596.

13.

Preliminary Studies on the Activity of Mixed Polyphenol-Heterocyclic Systems Against B16-F10 Melanoma Cancer Cells.

Duy Vo D, Rouaud I, Le Devehat F, Gautier F, Barillé-Nion S, Juin P, Levoin N, Boustie J, Grée R.

Med Chem. 2016;12(5):419-25.

PMID:
26825069
14.

TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL.

Thébault S, Agez M, Chi X, Stojko J, Cura V, Telerman SB, Maillet L, Gautier F, Billas-Massobrio I, Birck C, Troffer-Charlier N, Karafin T, Honoré J, Senff-Ribeiro A, Montessuit S, Johnson CM, Juin P, Cianférani S, Martinou JC, Andrews DW, Amson R, Telerman A, Cavarelli J.

Sci Rep. 2016 Jan 27;6:19725. doi: 10.1038/srep19725.

15.

Extraction and analysis of body-induced partials of guitar tones.

Fréour V, Gautier F, David B, Curtit M.

J Acoust Soc Am. 2015 Dec;138(6):3930-40. doi: 10.1121/1.4937749.

PMID:
26723347
16.

Quality assessment of combined quantization-shot-noise-induced decorrelation noise in high-speed digital holographic metrology.

Poittevin J, Picart P, Gautier F, Pezerat C.

Opt Express. 2015 Nov 30;23(24):30917-32. doi: 10.1364/OE.23.030917.

PMID:
26698724
17.

Evaluating hydrogen bonding control in the diastereoselective Diels-Alder reactions of 9-(2-aminoethyl)-anthracene derivatives.

Bawa RA, Gautier FM, Adams H, Meijer AJ, Jones S.

Org Biomol Chem. 2015 Nov 14;13(42):10569-77. doi: 10.1039/c5ob01343g. Epub 2015 Sep 4.

18.

A strategy for structuring and reporting a read-across prediction of toxicity.

Schultz TW, Amcoff P, Berggren E, Gautier F, Klaric M, Knight DJ, Mahony C, Schwarz M, White A, Cronin MT.

Regul Toxicol Pharmacol. 2015 Aug;72(3):586-601. doi: 10.1016/j.yrtph.2015.05.016. Epub 2015 May 21.

19.

Multi-point vibrometer based on high-speed digital in-line holography.

Poittevin J, Picart P, Faure C, Gautier F, Pézerat C.

Appl Opt. 2015 Apr 10;54(11):3185-96. doi: 10.1364/AO.54.003185.

PMID:
25967302
20.

Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision Making.

Berggren E, Amcoff P, Benigni R, Blackburn K, Carney E, Cronin M, Deluyker H, Gautier F, Judson RS, Kass GE, Keller D, Knight D, Lilienblum W, Mahony C, Rusyn I, Schultz T, Schwarz M, Schüürmann G, White A, Burton J, Lostia AM, Munn S, Worth A.

Environ Health Perspect. 2015 Dec;123(12):1232-40. doi: 10.1289/ehp.1409342. Epub 2015 May 8. Review.

21.

A combination of in silico and SAR studies to identify binding hot spots of Bcl-xL inhibitors.

Levoin N, Vo DD, Gautier F, Barillé-Nion S, Juin P, Tasseau O, Grée R.

Bioorg Med Chem. 2015 Apr 15;23(8):1747-57. doi: 10.1016/j.bmc.2015.02.060. Epub 2015 Mar 6.

22.

First evidence that oligopyridines, α-helix foldamers, inhibit Mcl-1 and sensitize ovarian carcinoma cells to Bcl-xL-targeting strategies.

Gloaguen C, Voisin-Chiret AS, Sopkova-de Oliveira Santos J, Fogha J, Gautier F, De Giorgi M, Burzicki G, Perato S, Pétigny-Lechartier C, Simonin-Le Jeune K, Brotin E, Goux D, N'Diaye M, Lambert B, Louis MH, Ligat L, Lopez F, Juin P, Bureau R, Rault S, Poulain L.

J Med Chem. 2015 Feb 26;58(4):1644-68. doi: 10.1021/jm500672y. Epub 2015 Feb 4.

PMID:
25585174
23.

Acoustic signature of violins based on bridge transfer mobility measurements.

Elie B, Gautier F, David B.

J Acoust Soc Am. 2014 Sep;136(3):1385. doi: 10.1121/1.4892762.

PMID:
25190411
24.

Bcl-xL controls a switch between cell death modes during mitotic arrest.

Bah N, Maillet L, Ryan J, Dubreil S, Gautier F, Letai A, Juin P, Barillé-Nion S.

Cell Death Dis. 2014 Jun 12;5:e1291. doi: 10.1038/cddis.2014.251. Erratum in: Cell Death Dis. 2014;5:e1429.

25.

Design, synthesis and biological evaluation of new inhibitors of Bax/Bcl-xL interaction in cancer cells.

Vo DD, Gautier F, Barillé-Nion S, Juin P, Levoin N, Grée R.

Bioorg Med Chem Lett. 2014 Apr 1;24(7):1758-61. doi: 10.1016/j.bmcl.2014.02.035. Epub 2014 Feb 24.

PMID:
24602902
26.

Decoding and unlocking the BCL-2 dependency of cancer cells.

Juin P, Geneste O, Gautier F, Depil S, Campone M.

Nat Rev Cancer. 2013 Jul;13(7):455-65. doi: 10.1038/nrc3538. Epub 2013 Jun 20. Review.

PMID:
23783119
27.

Retrospective exposure data for baby and children care products: an analysis of 48 clinical studies.

Gomez-Berrada MP, Gautier F, Parent-Massin D, Ferret PJ.

Food Chem Toxicol. 2013 Jul;57:185-94. doi: 10.1016/j.fct.2013.03.030. Epub 2013 Apr 2.

PMID:
23562927
28.

Hemisynthesis of selected embelin analogs and investigation of their proapoptotic activity against cancer cells.

Viault G, Babu KS, Gautier F, Barillé-Nion S, Juin P, Tasseau O, Grée R.

Med Chem. 2013 Dec;9(8):1028-34.

PMID:
23373598
29.

Evaluation of surface acoustic waves on the human skin using quasi-time-averaged digital Fresnel holograms.

Leclercq M, Karray M, Isnard V, Gautier F, Picart P.

Appl Opt. 2013 Jan 1;52(1):A136-46. doi: 10.1364/AO.52.00A136.

PMID:
23292386
30.

Macro parameters describing the mechanical behavior of classical guitars.

Elie B, Gautier F, David B.

J Acoust Soc Am. 2012 Dec;132(6):4013-24. doi: 10.1121/1.4765077.

PMID:
23231130
31.

Structure-activity relationship of selected polyphenol derivatives as inhibitors of Bax/Bcl-xL interaction.

Vo DD, Gautier F, Juin P, Grée R.

Eur J Med Chem. 2012 May;51:286-93. doi: 10.1016/j.ejmech.2012.02.036. Epub 2012 Feb 25.

PMID:
22425031
32.

Vibroacoustic characteristics of a gothic harp.

Daltrop S, Kotlicki A, Waltham C, Wolfe N, Elie B, Gautier F.

J Acoust Soc Am. 2012 Jan;131(1):837-43. doi: 10.1121/1.3651223.

PMID:
22280706
33.

Vibro-acoustics of organ pipes--revisiting the Miller experiment (L).

Gautier F, Nief G, Gilbert J, Dalmont JP.

J Acoust Soc Am. 2012 Jan;131(1):737-8. doi: 10.1121/1.3651792.

PMID:
22280696
34.

Scope of the organocatalysed asymmetric reductive amination of ketones with trichlorosilane.

Gautier FM, Jones S, Li X, Martin SJ.

Org Biomol Chem. 2011 Oct 26;9(22):7860-8. doi: 10.1039/c1ob05965c. Epub 2011 Sep 29.

PMID:
21960353
35.

ABT-737 and/or folate reverse the PDGF-induced alterations in the mitochondrial apoptotic pathway in low-grade glioma patients.

Debien E, Hervouet E, Gautier F, Juin P, Vallette FM, Cartron PF.

Clin Epigenetics. 2011 Aug;2(2):369-381. Epub 2011 May 15.

36.

c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1.

Campone M, Noël B, Couriaud C, Grau M, Guillemin Y, Gautier F, Gouraud W, Charbonnel C, Campion L, Jézéquel P, Braun F, Barré B, Coqueret O, Barillé-Nion S, Juin P.

Mol Cancer. 2011 Sep 7;10:110. doi: 10.1186/1476-4598-10-110.

37.

Combining carbohydrate substitutions at bioinspired positions with multivalent presentation towards optimising lectin inhibitors: case study with calixarenes.

André S, Grandjean C, Gautier FM, Bernardi S, Sansone F, Gabius HJ, Ungaro R.

Chem Commun (Camb). 2011 Jun 7;47(21):6126-8. doi: 10.1039/c1cc11163a. Epub 2011 Apr 26.

PMID:
21523264
38.

The iodosulfonamidation of peracetylated glycals revisited: access to 1,2-di-nitrogenated sugars.

Gautier FM, Djedaïni-Pilard F, Grandjean C.

Carbohydr Res. 2011 Apr 1;346(5):577-87. doi: 10.1016/j.carres.2011.01.022. Epub 2011 Jan 28.

PMID:
21333277
39.

Bax activation by engagement with, then release from, the BH3 binding site of Bcl-xL.

Gautier F, Guillemin Y, Cartron PF, Gallenne T, Cauquil N, Le Diguarher T, Casara P, Vallette FM, Manon S, Hickman JA, Geneste O, Juin P.

Mol Cell Biol. 2011 Feb;31(4):832-44. doi: 10.1128/MCB.00161-10. Epub 2010 Dec 20.

40.

Some characteristics of the concert harp's acoustic radiation.

Le Carrou JL, Leclere Q, Gautier F.

J Acoust Soc Am. 2010 May;127(5):3203-11. doi: 10.1121/1.3377055.

PMID:
21117768
41.

BIS response to tamponade and dobutamine in swine varies with hypnotic/opiate ratio.

Beydon L, Desfontis JC, Ganster F, Petres J, Gautier F, Ferec S, Cailleux A, Dussaussoy C, Liu N, Chazot T, Fischler M, Gogny M.

Ann Fr Anesth Reanim. 2009 Jul-Aug;28(7-8):650-7. doi: 10.1016/j.annfar.2009.05.014. Epub 2009 Jul 3.

PMID:
19577409
42.

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members.

Gallenne T, Gautier F, Oliver L, Hervouet E, Noël B, Hickman JA, Geneste O, Cartron PF, Vallette FM, Manon S, Juin P.

J Cell Biol. 2009 Apr 20;185(2):279-90. doi: 10.1083/jcb.200809153.

43.

Asymmetric reduction of ketimines with trichlorosilane employing an imidazole derived organocatalyst.

Gautier FM, Jones S, Martin SJ.

Org Biomol Chem. 2009 Jan 21;7(2):229-31. doi: 10.1039/b816051a. Epub 2008 Nov 19.

PMID:
19109665
44.

Influence of wall vibrations on the behavior of a simplified wind instrument.

Nief G, Gautier F, Dalmont JP, Gilbert J.

J Acoust Soc Am. 2008 Aug;124(2):1320-31. doi: 10.1121/1.2945157.

PMID:
18681617
45.

Effect of short-term treatment with meloxicam and pimobendan on the renal function in healthy beagle dogs.

Fusellier M, Desfontis JC, Le Roux A, Madec S, Gautier F, Thuleau A, Gogny M.

J Vet Pharmacol Ther. 2008 Apr;31(2):150-5. doi: 10.1111/j.1365-2885.2007.00934.x.

PMID:
18307507
46.

Pickering emulsions with stimulable particles: from highly- to weakly-covered interfaces.

Gautier F, Destribats M, Perrier-Cornet R, Dechézelles JF, Giermanska J, Héroguez V, Ravaine S, Leal-Calderon F, Schmitt V.

Phys Chem Chem Phys. 2007 Dec 28;9(48):6455-62. Epub 2007 Nov 13.

PMID:
18060177
47.

Influence of three anesthetic protocols on glomerular filtration rate in dogs.

Fusellier M, Desfontis JC, Madec S, Gautier F, Debailleul M, Gogny M.

Am J Vet Res. 2007 Aug;68(8):807-11.

PMID:
17669018
48.

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1.

Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P, Tasdemir E, Pierron G, Troulinaki K, Tavernarakis N, Hickman JA, Geneste O, Kroemer G.

EMBO J. 2007 May 16;26(10):2527-39. Epub 2007 Apr 19.

49.

Experimental study of AO and T1 modes of the concert harp.

Le Carrou JL, Gautier F, Foltête E.

J Acoust Soc Am. 2007 Jan;121(1):559-67.

PMID:
17297809
50.

The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death.

Manero F, Gautier F, Gallenne T, Cauquil N, Grée D, Cartron PF, Geneste O, Grée R, Vallette FM, Juin P.

Cancer Res. 2006 Mar 1;66(5):2757-64.

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