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Items: 1 to 50 of 718

1.

Baseline biomarkers of connectome disruption and atrophy predict future processing speed in early multiple sclerosis.

Kuceyeski A, Monohan E, Morris E, Fujimoto K, Vargas W, Gauthier SA.

Neuroimage Clin. 2018 May 8;19:417-424. doi: 10.1016/j.nicl.2018.05.003. eCollection 2018.

2.

Efficacy and safety of the compound Chinese medicine SaiLuoTong in vascular dementia: A randomized clinical trial.

Jia J, Wei C, Chen S, Li F, Tang Y, Qin W, Shi L, Gong M, Xu H, Li F, He J, Song H, Yang S, Zhou A, Wang F, Zuo X, Chu C, Liang J, Jia L, Gauthier S.

Alzheimers Dement (N Y). 2018 Mar 22;4:108-117. doi: 10.1016/j.trci.2018.02.004. eCollection 2018.

3.

Expert Consensus on Clinical Diagnostic Criteria for Fatal Familial Insomnia.

Wu LY, Zhan SQ, Huang ZY, Zhang B, Wang T, Liu CF, Lu H, Dong XP, Wu ZY, Zhang JW, Zhang JH, Zhao ZX, Han F, Huang Y, Lu J, Gauthier S, Jia JP, Wang YP.

Chin Med J (Engl). 2018 Jul 5;131(13):1613-1617. doi: 10.4103/0366-6999.235115. No abstract available.

4.

Behavioral Own-Body-Transformations in Children and Adolescents With Typical Development, Autism Spectrum Disorder, and Developmental Coordination Disorder.

Gauthier S, Anzalone SM, Cohen D, Zaoui M, Chetouani M, Villa F, Berthoz A, Xavier J.

Front Psychol. 2018 May 25;9:676. doi: 10.3389/fpsyg.2018.00676. eCollection 2018.

5.

Impact of the biological definition of Alzheimer's disease using amyloid, tau and neurodegeneration (ATN): what about the role of vascular changes, inflammation, Lewy body pathology?

Gauthier S, Zhang H, Ng KP, Pascoal TA, Rosa-Neto P.

Transl Neurodegener. 2018 May 31;7:12. doi: 10.1186/s40035-018-0117-9. eCollection 2018. Review.

6.

New thinking about thinking, part two. Theoretical articles for Alzheimer's & Dementia.

Khachaturian AS, Hayden KM, Mielke MM, Tang Y, Lutz MW, Gold M, Kukull WA, Mohs R, Gauthier S, Molinuevo JL, Zetterberg H, Khachaturian ZS.

Alzheimers Dement. 2018 Jun;14(6):703-706. doi: 10.1016/j.jalz.2018.05.002. Epub 2018 May 26. No abstract available.

PMID:
29842864
7.

Influence of Cu adatoms on the molecular assembly of 4,4'-bipyridine on Cu(111).

Dubois MA, Guillermet O, Gauthier S, Zhan G, Makoudi Y, Palmino F, Bouju X, Rochefort A.

Phys Chem Chem Phys. 2018 Jun 6;20(22):15350-15357. doi: 10.1039/c8cp01184b.

PMID:
29796573
8.

Individual variation, population-specific behaviours and stochastic processes shape marine migration phenologies.

Freshwater C, Trudel M, Beacham TD, Gauthier S, Johnson SC, Neville CE, Juanes F.

J Anim Ecol. 2018 May 23. doi: 10.1111/1365-2656.12852. [Epub ahead of print]

PMID:
29790171
9.

Noninvasive PK11195-PET Image Analysis Techniques Can Detect Abnormal Cerebral Microglial Activation in Parkinson's Disease.

Kang Y, Mozley PD, Verma A, Schlyer D, Henchcliffe C, Gauthier SA, Chiao PC, He B, Nikolopoulou A, Logan J, Sullivan JM, Pryor KO, Hesterman J, Kothari PJ, Vallabhajosula S.

J Neuroimaging. 2018 May 4. doi: 10.1111/jon.12519. [Epub ahead of print]

PMID:
29727504
10.

Acute prediction of outcome and cognitive-communication impairments following traumatic brain injury: The influence of age, education and site of lesion.

Gauthier S, LeBlanc J, Seresova A, Laberge-Poirier A, A Correa J, Alturki AY, Marcoux J, Maleki M, Feyz M, de Guise E.

J Commun Disord. 2018 May - Jun;73:77-90. doi: 10.1016/j.jcomdis.2018.04.003. Epub 2018 Apr 14.

PMID:
29709658
11.

Induction of disease remission with one cycle of alemtuzumab in relapsing-remitting MS.

Kocsik AS, Klein DE, Liedke M, Kaunzner UW, Nealon NM, Gauthier SA, Vartanian T, Perumal JS.

J Neurol. 2018 May;265(5):1226-1229. doi: 10.1007/s00415-018-8845-4. Epub 2018 Apr 17.

PMID:
29666985
12.

Current and projected cumulative impacts of fire, drought, and insects on timber volumes across Canada.

Boucher D, Boulanger Y, Aubin I, Bernier PY, Beaudoin A, Guindon L, Gauthier S.

Ecol Appl. 2018 Jul;28(5):1245-1259. doi: 10.1002/eap.1724. Epub 2018 Jun 5.

PMID:
29645330
13.

Fast and Robust Unsupervised Identification of MS Lesion Change Using the Statistical Detection of Changes Algorithm.

Nguyen TD, Zhang S, Gupta A, Zhao Y, Gauthier SA, Wang Y.

AJNR Am J Neuroradiol. 2018 May;39(5):830-833. doi: 10.3174/ajnr.A5594. Epub 2018 Mar 8.

PMID:
29519791
14.

Magnetic susceptibility increases as diamagnetic molecules breakdown: Myelin digestion during multiple sclerosis lesion formation contributes to increase on QSM.

Deh K, Ponath GD, Molvi Z, Parel GT, Gillen KM, Zhang S, Nguyen TD, Spincemaille P, Ma Y, Gupta A, Gauthier SA, Pitt D, Wang Y.

J Magn Reson Imaging. 2018 Mar 8. doi: 10.1002/jmri.25997. [Epub ahead of print]

PMID:
29517817
15.

Targeting Alzheimer's Disease at the Right Time and the Right Place: Validation of a Personalized Approach to Diagnosis and Treatment.

Gauthier S, Ng KP, Pascoal TA, Zhang H, Rosa-Neto P.

J Alzheimers Dis. 2018;64(s1):S23-S31. doi: 10.3233/JAD-179924.

16.

Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease.

Villeneuve S, Vogel JW, Gonneaud J, Pichet Binette A, Rosa-Neto P, Gauthier S, Bateman RJ, Fagan AM, Morris JC, Benzinger TLS, Johnson SC, Breitner JCS, Poirier J; Presymptomatic Evaluation of Novel or Experimental Treatments for Alzheimer Disease (PREVENT-AD) Research Group.

JAMA Neurol. 2018 May 1;75(5):608-619. doi: 10.1001/jamaneurol.2017.5135.

PMID:
29482212
17.

Corrigendum to "Hippocampus and amygdala volumes from magnetic resonance images in children: Assessing accuracy of FreeSurfer and FSL against manual segmentation"[NeuroImage 129 (2016) 1-14].

Schoemaker D, Buss C, Head K, Sandman CA, Davis EP, Chakravarty MM, Gauthier S, Pruessner JC.

Neuroimage. 2018 Jun;173:1-2. doi: 10.1016/j.neuroimage.2018.02.009. Epub 2018 Feb 21. No abstract available.

PMID:
29477029
18.

CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.

Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang MS, Gauthier S, Rouleau GA, Poirier J, Bennett DA, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative.

Neurol Genet. 2018 Jan 30;4(1):e216. doi: 10.1212/NXG.0000000000000216. eCollection 2018 Feb.

19.

Push-pull D-π-Ru-π-A chromophores: synthesis and electrochemical, photophysical and second-order nonlinear optical properties.

Durand RJ, Gauthier S, Achelle S, Groizard T, Kahlal S, Saillard JY, Barsella A, Le Poul N, Le Guen FR.

Dalton Trans. 2018 Mar 12;47(11):3965-3975. doi: 10.1039/c8dt00093j.

PMID:
29464264
20.

Dementia clinical trial implications of mild behavioral impairment.

Mortby ME, Black SE, Gauthier S, Miller D, Porsteinsson A, Smith EE, Ismail Z.

Int Psychogeriatr. 2018 Feb;30(2):171-175. doi: 10.1017/S1041610218000042.

PMID:
29448970
21.

Anosognosia predicts default mode network hypometabolism and clinical progression to dementia.

Therriault J, Ng KP, Pascoal TA, Mathotaarachchi S, Kang MS, Struyfs H, Shin M, Benedet AL, Walpola IC, Nair V, Gauthier S, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative.

Neurology. 2018 Mar 13;90(11):e932-e939. doi: 10.1212/WNL.0000000000005120. Epub 2018 Feb 14.

22.

The cost of Alzheimer's disease in China and re-estimation of costs worldwide.

Jia J, Wei C, Chen S, Li F, Tang Y, Qin W, Zhao L, Jin H, Xu H, Wang F, Zhou A, Zuo X, Wu L, Han Y, Han Y, Huang L, Wang Q, Li D, Chu C, Shi L, Gong M, Du Y, Zhang J, Zhang J, Zhou C, Lv J, Lv Y, Xie H, Ji Y, Li F, Yu E, Luo B, Wang Y, Yang S, Qu Q, Guo Q, Liang F, Zhang J, Tan L, Shen L, Zhang K, Zhang J, Peng D, Tang M, Lv P, Fang B, Chu L, Jia L, Gauthier S.

Alzheimers Dement. 2018 Apr;14(4):483-491. doi: 10.1016/j.jalz.2017.12.006. Epub 2018 Feb 9.

PMID:
29433981
23.

Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer's disease.

Pascoal TA, Mathotaarachchi S, Shin M, Park AY, Mohades S, Benedet AL, Kang MS, Massarweh G, Soucy JP, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative.

Eur J Nucl Med Mol Imaging. 2018 Jun;45(6):1021-1030. doi: 10.1007/s00259-018-3933-3. Epub 2018 Feb 2.

24.

Diagnostic accuracy of semiautomatic lesion detection plus quantitative susceptibility mapping in the identification of new and enhancing multiple sclerosis lesions.

Zhang S, Nguyen TD, Zhao Y, Gauthier SA, Wang Y, Gupta A.

Neuroimage Clin. 2018 Jan 28;18:143-148. doi: 10.1016/j.nicl.2018.01.013. eCollection 2018.

25.

Quantitative Susceptibility Mapping of the Thalamus: Relationships with Thalamic Volume, Total Gray Matter Volume, and T2 Lesion Burden.

Chiang GC, Hu J, Morris E, Wang Y, Gauthier SA.

AJNR Am J Neuroradiol. 2018 Jan 25. doi: 10.3174/ajnr.A5537. [Epub ahead of print]

PMID:
29371258
26.

MEMO+: Efficacy, Durability and Effect of Cognitive Training and Psychosocial Intervention in Individuals with Mild Cognitive Impairment.

Belleville S, Hudon C, Bier N, Brodeur C, Gilbert B, Grenier S, Ouellet MC, Viscogliosi C, Gauthier S.

J Am Geriatr Soc. 2018 Apr;66(4):655-663. doi: 10.1111/jgs.15192. Epub 2018 Jan 4.

PMID:
29313875
27.

Impacts of salvage logging on biodiversity: a meta-analysis.

Thorn S, Bässler C, Brandl R, Burton PJ, Cahall R, Campbell JL, Castro J, Choi CY, Cobb T, Donato DC, Durska E, Fontaine JB, Gauthier S, Hebert C, Hothorn T, Hutto RL, Lee EJ, Leverkus AB, Lindenmayer DB, Obrist MK, Rost J, Seibold S, Seidl R, Thom D, Waldron K, Wermelinger B, Winter MB, Zmihorski M, Müller J.

J Appl Ecol. 2018 Jan;55(1):279-289. doi: 10.1111/1365-2664.12945. Epub 2017 Jul 5.

PMID:
29276308
28.

Comparative effect of statins on the risk of incident Alzheimer disease.

Sinyavskaya L, Gauthier S, Renoux C, Dell'Aniello S, Suissa S, Brassard P.

Neurology. 2018 Jan 16;90(3):e179-e187. doi: 10.1212/WNL.0000000000004818. Epub 2017 Dec 15.

PMID:
29247073
29.

Combining Quantitative Susceptibility Mapping with Automatic Zero Reference (QSM0) and Myelin Water Fraction Imaging to Quantify Iron-Related Myelin Damage in Chronic Active MS Lesions.

Yao Y, Nguyen TD, Pandya S, Zhang Y, Hurtado Rúa S, Kovanlikaya I, Kuceyeski A, Liu Z, Wang Y, Gauthier SA.

AJNR Am J Neuroradiol. 2018 Feb;39(2):303-310. doi: 10.3174/ajnr.A5482. Epub 2017 Dec 14.

PMID:
29242359
30.

EU/US/CTAD Task Force: Lessons Learned from Recent and Current Alzheimer's Prevention Trials.

Aisen P, Touchon J, Amariglio R, Andrieu S, Bateman R, Breitner J, Donohue M, Dunn B, Doody R, Fox N, Gauthier S, Grundman M, Hendrix S, Ho C, Isaac M, Raman R, Rosenberg P, Schindler R, Schneider L, Sperling R, Tariot P, Welsh-Bohmer K, Weiner M, Vellas B.

J Prev Alzheimers Dis. 2017;4(2):116-124. doi: 10.14283/jpad.2017.13.

31.

Dependence Levels as Interim Clinical Milestones Along the Continuum of Alzheimer's Disease: 18-Month Results from the GERAS Observational Study.

Kahle-Wrobleski K, Andrews JS, Belger M, Ye W, Gauthier S, Rentz DM, Galasko D.

J Prev Alzheimers Dis. 2017;4(2):72-80. doi: 10.14283/jpad.2017.2.

32.

Clinical Effects of Tramiprosate in APOE4/4 Homozygous Patients with Mild Alzheimer's Disease Suggest Disease Modification Potential.

Abushakra S, Porsteinsson A, Scheltens P, Sadowsky C, Vellas B, Cummings J, Gauthier S, Hey JA, Power A, Wang P, Shen L, Tolar M.

J Prev Alzheimers Dis. 2017;4(3):149-156. doi: 10.14283/jpad.2017.26.

PMID:
29182706
33.

Characterizing biomarker features of cognitively normal individuals with ventriculomegaly.

Li X, Ba M, Ng KP, Mathotaarachchi S, Pascoal TA, Rosa-Neto P, Gauthier S.

Alzheimers Dement (Amst). 2017 Sep 5;10:12-21. doi: 10.1016/j.dadm.2017.08.001. eCollection 2018.

34.

Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.

Wilcock GK, Gauthier S, Frisoni GB, Jia J, Hardlund JH, Moebius HJ, Bentham P, Kook KA, Schelter BO, Wischik DJ, Davis CS, Staff RT, Vuksanovic V, Ahearn T, Bracoud L, Shamsi K, Marek K, Seibyl J, Riedel G, Storey JMD, Harrington CR, Wischik CM.

J Alzheimers Dis. 2018;61(1):435-457. doi: 10.3233/JAD-170560.

35.

Progress in transnational scientific and ethics review: Commentary on the proposal for a single North American review board for research on dementia.

Gauthier S, Robillard J, de Champlain J.

Alzheimers Dement. 2018 Jan;14(1):115-116. doi: 10.1016/j.jalz.2017.10.001. Epub 2017 Oct 28. No abstract available.

PMID:
29111430
36.

Multimodal Imaging in Rat Model Recapitulates Alzheimer's Disease Biomarkers Abnormalities.

Parent MJ, Zimmer ER, Shin M, Kang MS, Fonov VS, Mathieu A, Aliaga A, Kostikov A, Do Carmo S, Dea D, Poirier J, Soucy JP, Gauthier S, Cuello AC, Rosa-Neto P.

J Neurosci. 2017 Dec 13;37(50):12263-12271. doi: 10.1523/JNEUROSCI.1346-17.2017. Epub 2017 Nov 2.

37.

Author response: Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.

Gauthier S, Ng KP, Pascoal TA, Mathotaarachchi S, Chung CO, Benedetti AL, Shin M, Kang MS, Li X, Ba M, Kandiah N, Rosa-Neto P.

Neurology. 2017 Oct 31;89(18):1931. doi: 10.1212/WNL.0000000000004593. No abstract available.

PMID:
29084927
38.

The prevalence and biomarkers' characteristic of rapidly progressive Alzheimer's disease from the Alzheimer's Disease Neuroimaging Initiative database.

Ba M, Li X, Ng KP, Pascoal TA, Mathotaarachchi S, Rosa-Neto P, Gauthier S; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement (N Y). 2017 Feb 9;3(1):107-113. doi: 10.1016/j.trci.2016.12.005. eCollection 2017 Jan.

39.

Reversible Redox Switching of Chromophoric Phenylmethylenepyrans by Carbon-Carbon Bond Making/Breaking.

Wojcik L, Michaud F, Gauthier S, Cabon N, Le Poul P, Gloaguen F, Le Poul N.

J Org Chem. 2017 Dec 1;82(23):12395-12405. doi: 10.1021/acs.joc.7b02199. Epub 2017 Oct 31.

40.

Treatment effects of Ginkgo biloba extract EGb 761® on the spectrum of behavioral and psychological symptoms of dementia: meta-analysis of randomized controlled trials.

Savaskan E, Mueller H, Hoerr R, von Gunten A, Gauthier S.

Int Psychogeriatr. 2018 Mar;30(3):285-293. doi: 10.1017/S1041610217001892. Epub 2017 Sep 21.

41.

Quantification of brain cholinergic denervation in Alzheimer's disease using PET imaging with [18F]-FEOBV.

Aghourian M, Legault-Denis C, Soucy JP, Rosa-Neto P, Gauthier S, Kostikov A, Gravel P, Bédard MA.

Mol Psychiatry. 2017 Nov;22(11):1531-1538. doi: 10.1038/mp.2017.183. Epub 2017 Sep 12.

PMID:
28894304
42.

Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities.

Gauthier SA, Pérez-González R, Sharma A, Huang FK, Alldred MJ, Pawlik M, Kaur G, Ginsberg SD, Neubert TA, Levy E.

Acta Neuropathol Commun. 2017 Aug 29;5(1):65. doi: 10.1186/s40478-017-0466-0.

43.

Familiarity deficits in cognitively normal aging individuals with APOE ε4: A follow-up investigation of medial temporal lobe structural correlates.

Schoemaker D, Poirier J, Collins DL, Gauthier S, Pruessner JC.

Alzheimers Dement (Amst). 2017 Jun 15;9:21-24. doi: 10.1016/j.dadm.2017.05.008. eCollection 2017.

44.

Identifying incipient dementia individuals using machine learning and amyloid imaging.

Mathotaarachchi S, Pascoal TA, Shin M, Benedet AL, Kang MS, Beaudry T, Fonov VS, Gauthier S, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative.

Neurobiol Aging. 2017 Nov;59:80-90. doi: 10.1016/j.neurobiolaging.2017.06.027. Epub 2017 Jul 11.

45.

Quantifying the Susceptibility Variation of Normal-Appearing White Matter in Multiple Sclerosis by Quantitative Susceptibility Mapping.

Chen W, Zhang Y, Mu K, Pan C, Gauthier SA, Zhu W, Wang Y.

AJR Am J Roentgenol. 2017 Oct;209(4):889-894. doi: 10.2214/AJR.16.16851. Epub 2017 Jul 13.

PMID:
28705068
46.

Reduction of PK11195 uptake observed in multiple sclerosis lesions after natalizumab initiation.

Kaunzner UW, Kang Y, Monohan E, Kothari PJ, Nealon N, Perumal J, Vartanian T, Kuceyeski A, Vallabhajosula S, Mozley PD, Riley CS, Newman SM, Gauthier SA.

Mult Scler Relat Disord. 2017 Jul;15:27-33. doi: 10.1016/j.msard.2017.04.008. Epub 2017 Apr 29.

PMID:
28641769
47.

A developmental and clinical perspective of rhythmic interpersonal coordination: From mimicry toward the interconnection of minds.

Xavier J, Magnat J, Sherman A, Gauthier S, Cohen D, Chaby L.

J Physiol Paris. 2016 Nov;110(4 Pt B):420-426. doi: 10.1016/j.jphysparis.2017.06.001. Epub 2017 Jul 4. Review.

PMID:
28625683
48.

MRI in the assessment and monitoring of multiple sclerosis: an update on best practice.

Kaunzner UW, Gauthier SA.

Ther Adv Neurol Disord. 2017 Jun;10(6):247-261. doi: 10.1177/1756285617708911. Epub 2017 May 12. Review.

49.

MRI Analysis of White Matter Myelin Water Content in Multiple Sclerosis: A Novel Approach Applied to Finding Correlates of Cortical Thinning.

Dayan M, Hurtado Rúa SM, Monohan E, Fujimoto K, Pandya S, LoCastro EM, Vartanian T, Nguyen TD, Raj A, Gauthier SA.

Front Neurosci. 2017 May 26;11:284. doi: 10.3389/fnins.2017.00284. eCollection 2017.

50.

Application of calibrated fMRI in Alzheimer's disease.

Lajoie I, Nugent S, Debacker C, Dyson K, Tancredi FB, Badhwar A, Belleville S, Deschaintre Y, Bellec P, Doyon J, Bocti C, Gauthier S, Arnold D, Kergoat MJ, Chertkow H, Monchi O, Hoge RD.

Neuroimage Clin. 2017 May 16;15:348-358. doi: 10.1016/j.nicl.2017.05.009. eCollection 2017.

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