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Items: 1 to 50 of 334

1.

Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis.

Lamort AS, Hamon Y, Czaplewski C, Gieldon A, Seren S, Coquet L, Lecaille F, Lesner A, Lalmanach G, Gauthier F, Jenne D, Korkmaz B.

Int J Mol Sci. 2019 Sep 25;20(19). pii: E4747. doi: 10.3390/ijms20194747.

2.

Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C.

Korkmaz B, Lesner A, Wysocka M, Gieldon A, Håkansson M, Gauthier F, Logan DT, Jenne DE, Lauritzen C, Pedersen J.

Biochem Pharmacol. 2019 Jun;164:349-367. doi: 10.1016/j.bcp.2019.04.006. Epub 2019 Apr 9.

PMID:
30978322
3.

Green versus blue: Randomized controlled trial comparing indocyanine green with methylene blue for sentinel lymph node detection in endometrial cancer.

Rozenholc A, Samouelian V, Warkus T, Gauthier P, Provencher D, Sauthier P, Gauthier F, Drakopoulos P, Cormier B.

Gynecol Oncol. 2019 Jun;153(3):500-504. doi: 10.1016/j.ygyno.2019.03.103. Epub 2019 Mar 20.

PMID:
30902369
4.

Immature Granulocytes: A Risk Factor of Infection after Cardiac Surgery.

Daix T, Guérin E, Tavernier E, Marsaud JP, Hacan A, Gauthier F, Piccardo A, Vignon P, Feuillard J, François B.

Cytometry B Clin Cytom. 2018 Nov;94(6):887-894. doi: 10.1002/cyto.b.21739. Epub 2018 Oct 16.

PMID:
30328273
5.

MSPminer: abundance-based reconstitution of microbial pan-genomes from shotgun metagenomic data.

Plaza Oñate F, Le Chatelier E, Almeida M, Cervino ACL, Gauthier F, Magoulès F, Ehrlich SD, Pichaud M.

Bioinformatics. 2019 May 1;35(9):1544-1552. doi: 10.1093/bioinformatics/bty830.

6.

Gymnotic delivery and gene silencing activity of reduction-responsive siRNAs bearing lipophilic disulfide-containing modifications at 2'-position.

Gauthier F, Claveau S, Bertrand JR, Vasseur JJ, Dupouy C, Debart F.

Bioorg Med Chem. 2018 Sep 1;26(16):4635-4643. doi: 10.1016/j.bmc.2018.07.033. Epub 2018 Jul 27.

PMID:
30121212
7.

Subtotal and total splenectomy for hereditary pyropoikilocytosis: Benefits and outcomes.

Pincez T, Guitton C, Landman-Parker J, Brousse V, Gauthier F, Da Costa L, Ghazal K, Dufillot D, Tchernia G, Picard V, Garçon L.

Am J Hematol. 2018 Oct;93(10):E340-E342. doi: 10.1002/ajh.25223. Epub 2018 Sep 26. No abstract available.

8.

The efficacy of surgical shunts to treat severe portal hypertension after a Kasai procedure for biliary atresia.

Guérin F, Charre L, Jasienski S, Duché M, Franchiabella S, Bernard O, Jacquemin E, Agostini H, Gauthier F, Branchereau S.

J Pediatr Surg. 2019 Mar;54(3):531-536. doi: 10.1016/j.jpedsurg.2018.06.023. Epub 2018 Jun 25.

PMID:
29983186
9.

Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.

Seren S, Rashed Abouzaid M, Eulenberg-Gustavus C, Hirschfeld J, Nasr Soliman H, Jerke U, N'Guessan K, Dallet-Choisy S, Lesner A, Lauritzen C, Schacher B, Eickholz P, Nagy N, Szell M, Croix C, Viaud-Massuard MC, Al Farraj Aldosari A, Ragunatha S, Ibrahim Mostafa M, Giampieri F, Battino M, Cornillier H, Lorette G, Stephan JL, Goizet C, Pedersen J, Gauthier F, Jenne DE, Marchand-Adam S, Chapple IL, Kettritz R, Korkmaz B.

J Biol Chem. 2018 Aug 10;293(32):12415-12428. doi: 10.1074/jbc.RA118.001922. Epub 2018 Jun 20.

10.

Therapeutic targeting of cathepsin C: from pathophysiology to treatment.

Korkmaz B, Caughey GH, Chapple I, Gauthier F, Hirschfeld J, Jenne DE, Kettritz R, Lalmanach G, Lamort AS, Lauritzen C, Łȩgowska M, Lesner A, Marchand-Adam S, McKaig SJ, Moss C, Pedersen J, Roberts H, Schreiber A, Seren S, Thakker NS.

Pharmacol Ther. 2018 Oct;190:202-236. doi: 10.1016/j.pharmthera.2018.05.011. Epub 2018 May 26. Review.

PMID:
29842917
11.

A 2',2'-disulfide-bridged dinucleotide conformationally locks RNA hairpins.

Gauthier F, Beltran F, Biscans A, Debart F, Dupouy C, Vasseur JJ.

Org Biomol Chem. 2018 May 2;16(17):3181-3188. doi: 10.1039/c8ob00328a.

PMID:
29645048
12.

Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis.

Guarino C, Gruba N, Grzywa R, Dyguda-Kazimierowicz E, Hamon Y, Łȩgowska M, Skoreński M, Dallet-Choisy S, Marchand-Adam S, Kellenberger C, Jenne DE, Sieńczyk M, Lesner A, Gauthier F, Korkmaz B.

J Med Chem. 2018 Mar 8;61(5):1858-1870. doi: 10.1021/acs.jmedchem.7b01416. Epub 2018 Feb 26.

PMID:
29442501
13.

Long-term outcome of liver transplantation in childhood: A study of 20-year survivors.

Martinelli J, Habes D, Majed L, Guettier C, Gonzalès E, Linglart A, Larue C, Furlan V, Pariente D, Baujard C, Branchereau S, Gauthier F, Jacquemin E, Bernard O.

Am J Transplant. 2018 Jul;18(7):1680-1689. doi: 10.1111/ajt.14626. Epub 2018 Jan 12.

14.

Hepatic Portocholecystostomy: 97 Cases From a Single Institution.

Hery G, Gonzales E, Bernard O, Fouquet V, Gauthier F, Branchereau S.

J Pediatr Gastroenterol Nutr. 2017 Oct;65(4):375-379. doi: 10.1097/MPG.0000000000001685.

PMID:
28742721
15.

Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.

Guarino C, Hamon Y, Croix C, Lamort AS, Dallet-Choisy S, Marchand-Adam S, Lesner A, Baranek T, Viaud-Massuard MC, Lauritzen C, Pedersen J, Heuzé-Vourc'h N, Si-Tahar M, Fıratlı E, Jenne DE, Gauthier F, Horwitz MS, Borregaard N, Korkmaz B.

Biochem Pharmacol. 2017 May 1;131:52-67. doi: 10.1016/j.bcp.2017.02.009. Epub 2017 Feb 11.

PMID:
28193451
16.

The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection.

Chevaleyre C, Riou M, Bréa D, Vandebrouck C, Barc C, Pezant J, Melo S, Olivier M, Delaunay R, Boulesteix O, Berthon P, Rossignol C, Burlaud Gaillard J, Becq F, Gauthier F, Si-Tahar M, Meurens F, Berri M, Caballero-Posadas I, Attucci S.

PLoS One. 2016 Dec 16;11(12):e0168577. doi: 10.1371/journal.pone.0168577. eCollection 2016.

17.

Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.

Korkmaz B, Lesner A, Guarino C, Wysocka M, Kellenberger C, Watier H, Specks U, Gauthier F, Jenne DE.

Pharmacol Rev. 2016 Jul;68(3):603-30. doi: 10.1124/pr.115.012104. Review.

PMID:
27329045
18.

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

Hamon Y, Legowska M, Hervé V, Dallet-Choisy S, Marchand-Adam S, Vanderlynden L, Demonte M, Williams R, Scott CJ, Si-Tahar M, Heuzé-Vourc'h N, Lalmanach G, Jenne DE, Lesner A, Gauthier F, Korkmaz B.

J Biol Chem. 2016 Apr 15;291(16):8486-99. doi: 10.1074/jbc.M115.707109. Epub 2016 Feb 16.

19.

Long-term follow-up of subtotal splenectomy for hereditary spherocytosis: a single-center study.

Pincez T, Guitton C, Gauthier F, de Lambert G, Picard V, Fénéant-Thibault M, Turhan A, Mohandas N, Tchernia G, Garçon L.

Blood. 2016 Mar 24;127(12):1616-8. doi: 10.1182/blood-2015-11-679357. Epub 2016 Jan 15. No abstract available.

20.

Surgical Management of Neuroendocrine Tumors of the Appendix in Children and Adolescents: A Retrospective French Multicenter Study of 114 Cases.

de Lambert G, Lardy H, Martelli H, Orbach D, Gauthier F, Guérin F.

Pediatr Blood Cancer. 2016 Apr;63(4):598-603. doi: 10.1002/pbc.25823. Epub 2015 Dec 10.

PMID:
26663900
21.

Equipment failures and their contribution to industrial incidents and accidents in the manufacturing industry.

Bourassa D, Gauthier F, Abdul-Nour G.

Int J Occup Saf Ergon. 2016;22(1):131-41. doi: 10.1080/10803548.2015.1116814.

PMID:
26652772
22.

Analysis of urinary cathepsin C for diagnosing Papillon-Lefèvre syndrome.

Hamon Y, Legowska M, Fergelot P, Dallet-Choisy S, Newell L, Vanderlynden L, Kord Valeshabad A, Acrich K, Kord H, Charalampos T, Morice-Picard F, Surplice I, Zoidakis J, David K, Vlahou A, Ragunatha S, Nagy N, Farkas K, Széll M, Goizet C, Schacher B, Battino M, Al Farraj Aldosari A, Wang X, Liu Y, Marchand-Adam S, Lesner A, Kara E, Korkmaz-Icöz S, Moss C, Eickholz P, Taieb A, Kavukcu S, Jenne DE, Gauthier F, Korkmaz B.

FEBS J. 2016 Feb;283(3):498-509. doi: 10.1111/febs.13605. Epub 2016 Jan 4.

23.

Pharmacological Activities and Hydrolysis by Peptidases of [Phospho-Ser(6)]-Bradykinin (pS(6)-BK).

Assis DM, Juliano L, Paschoalin T, Kouyoumdjian M, Calixto JB, Santos RA, Pertinhez TA, Gauthier F, Moreau T, Blaber M, Juliano MA.

Biochem Pharmacol. 2015 Sep 15;97(2):203-14. doi: 10.1016/j.bcp.2015.07.033. Epub 2015 Jul 31.

PMID:
26235942
24.

Tennis Racket Vibrations and Shock Transmission to the Wrist during Forehand Drive.

Rogowski I, Creveaux T, Triquigneaux S, Macé P, Gauthier F, Sevrez V.

PLoS One. 2015 Jul 15;10(7):e0132925. doi: 10.1371/journal.pone.0132925. eCollection 2015.

25.

New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.

Guarino C, Legowska M, Epinette C, Kellenberger C, Dallet-Choisy S, Sieńczyk M, Gabant G, Cadene M, Zoidakis J, Vlahou A, Wysocka M, Marchand-Adam S, Jenne DE, Lesner A, Gauthier F, Korkmaz B.

J Biol Chem. 2014 Nov 14;289(46):31777-91. doi: 10.1074/jbc.M114.591339. Epub 2014 Oct 6.

26.

Ovarian tumors in children and adolescents: a series of 41 cases.

Péroux E, Franchi-Abella S, Sainte-Croix D, Canale S, Gauthier F, Martelli H, Pariente D, Adamsbaum C.

Diagn Interv Imaging. 2015 Mar;96(3):273-82. doi: 10.1016/j.diii.2014.07.001. Epub 2014 Sep 16.

27.

Mesenchymal hamartoma or embryonal sarcoma of the liver in childhood: a difficult diagnosis before complete surgical excision.

Wildhaber BE, Montaruli E, Guérin F, Branchereau S, Martelli H, Gauthier F.

J Pediatr Surg. 2014 Sep;49(9):1372-7. doi: 10.1016/j.jpedsurg.2014.04.005. Epub 2014 May 15.

PMID:
25148740
28.

OptiMAS: a decision support tool to conduct marker-assisted selection programs.

Valente F, Gauthier F, Bardol N, Blanc G, Joets J, Charcosset A, Moreau L.

Methods Mol Biol. 2014;1145:97-116. doi: 10.1007/978-1-4939-0446-4_9.

PMID:
24816663
29.

Congenital portosystemic shunts in children: a new anatomical classification correlated with surgical strategy.

Blanc T, Guerin F, Franchi-Abella S, Jacquemin E, Pariente D, Soubrane O, Branchereau S, Gauthier F.

Ann Surg. 2014 Jul;260(1):188-98. doi: 10.1097/SLA.0000000000000266.

PMID:
24169154
30.

Hot regions of noninterfering crossovers coexist with a nonuniformly interfering pathway in Arabidopsis thaliana.

Basu-Roy S, Gauthier F, Giraut L, Mézard C, Falque M, Martin OC.

Genetics. 2013 Nov;195(3):769-79. doi: 10.1534/genetics.113.155549. Epub 2013 Sep 11.

31.

Poly-L-Lysine compacts DNA, kills bacteria, and improves protease inhibition in cystic fibrosis sputum.

Dubois AV, Midoux P, Gras D, Si-Tahar M, Bréa D, Attucci S, Khelloufi MK, Ramphal R, Diot P, Gauthier F, Hervé V.

Am J Respir Crit Care Med. 2013 Sep 15;188(6):703-9. doi: 10.1164/rccm.201305-0912OC.

PMID:
23947381
32.

Extrahepatic vitelline vein aneurysm: prenatal diagnosis and follow up.

Héry G, Quarello E, Gorincour G, Franchi S, Gauthier F, de Lagausie P.

J Pediatr Surg. 2013 Aug;48(8):e1-4. doi: 10.1016/j.jpedsurg.2013.06.007.

PMID:
23932633
33.

[Hazardous endocrine disruptors. Phthalates in our hospital].

Cordey L, Gauthier F.

Krankenpfl Soins Infirm. 2013;106(7):74-5. French. No abstract available.

PMID:
23894882
34.

Relevance of the mouse model as a therapeutic approach for neutrophil proteinase 3-associated human diseases.

Korkmaz B, Jenne DE, Gauthier F.

Int Immunopharmacol. 2013 Dec;17(4):1198-205. doi: 10.1016/j.intimp.2013.07.003. Epub 2013 Jul 23. Review.

PMID:
23886601
35.

[Guidelines for diagnosis of acute appendicitis in childhood].

Gauthier F, de Lambert G, Guérin F, Goldszmidt D, Martelli H.

Rev Prat. 2013 Apr;63(4):524-9. French.

PMID:
23682484
36.

OptiMAS: a decision support tool for marker-assisted assembly of diverse alleles.

Valente F, Gauthier F, Bardol N, Blanc G, Joets J, Charcosset A, Moreau L.

J Hered. 2013 Jul-Aug;104(4):586-90. doi: 10.1093/jhered/est020. Epub 2013 Apr 10.

37.

Improving outcomes of biliary atresia: French national series 1986-2009.

Chardot C, Buet C, Serinet MO, Golmard JL, Lachaux A, Roquelaure B, Gottrand F, Broué P, Dabadie A, Gauthier F, Jacquemin E.

J Hepatol. 2013 Jun;58(6):1209-17. doi: 10.1016/j.jhep.2013.01.040. Epub 2013 Feb 8.

PMID:
23402746
38.

Congenital portosystemic shunts in children: recognition, evaluation, and management.

Bernard O, Franchi-Abella S, Branchereau S, Pariente D, Gauthier F, Jacquemin E.

Semin Liver Dis. 2012 Nov;32(4):273-87. doi: 10.1055/s-0032-1329896. Epub 2013 Feb 8. Review.

PMID:
23397528
39.

Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis).

Korkmaz B, Lesner A, Letast S, Mahdi YK, Jourdan ML, Dallet-Choisy S, Marchand-Adam S, Kellenberger C, Viaud-Massuard MC, Jenne DE, Gauthier F.

Semin Immunopathol. 2013 Jul;35(4):411-21. doi: 10.1007/s00281-013-0362-z. Epub 2013 Feb 6. Review.

PMID:
23385856
40.

[Consumption of psychoactive substances by caregivers].

Gauthier F.

Rev Infirm. 2012 Nov;(185):25-6. French.

PMID:
23173489
41.

Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin.

Derache C, Epinette C, Roussel A, Gabant G, Cadene M, Korkmaz B, Gauthier F, Kellenberger C.

FEBS J. 2012 Dec;279(24):4466-78. doi: 10.1111/febs.12033. Epub 2012 Nov 12.

42.

Selective inhibitors of human neutrophil proteinase 3.

Korkmaz B, Kellenberger C, Viaud-Massuard MC, Gauthier F.

Curr Pharm Des. 2013;19(6):966-76. Review.

PMID:
23016687
43.

The pig as a model for investigating the role of neutrophil serine proteases in human inflammatory lung diseases.

Bréa D, Meurens F, Dubois AV, Gaillard J, Chevaleyre C, Jourdan ML, Winter N, Arbeille B, Si-Tahar M, Gauthier F, Attucci S.

Biochem J. 2012 Nov 1;447(3):363-70. doi: 10.1042/BJ20120818.

44.

Three wavelength substrate system of neutrophil serine proteinases.

Wysocka M, Lesner A, Gruba N, Korkmaz B, Gauthier F, Kitamatsu M, Łęgowska A, Rolka K.

Anal Chem. 2012 Aug 21;84(16):7241-8. doi: 10.1021/ac301684w. Epub 2012 Aug 8.

PMID:
22823539
45.

Congenital portosystemic vascular malformations.

Guérin F, Blanc T, Gauthier F, Abella SF, Branchereau S.

Semin Pediatr Surg. 2012 Aug;21(3):233-44. doi: 10.1053/j.sempedsurg.2012.05.006. Review.

PMID:
22800976
46.

Experimental analysis of 31 risk estimation tools applied to safety of machinery.

Gauthier F, Lambert S, Chinniah Y.

Int J Occup Saf Ergon. 2012;18(2):245-65.

PMID:
22721542
47.

Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice.

Steinwede K, Maus R, Bohling J, Voedisch S, Braun A, Ochs M, Schmiedl A, Länger F, Gauthier F, Roes J, Welte T, Bange FC, Niederweis M, Bühling F, Maus UA.

J Immunol. 2012 May 1;188(9):4476-87. doi: 10.4049/jimmunol.1103346. Epub 2012 Mar 28.

48.

The long-term outcome of hepatic artery thrombosis after liver transplantation in children: role of urgent revascularization.

Ackermann O, Branchereau S, Franchi-Abella S, Pariente D, Chevret L, Debray D, Jacquemin E, Gauthier F, Hill C, Bernard O.

Am J Transplant. 2012 Jun;12(6):1496-503. doi: 10.1111/j.1600-6143.2011.03984.x. Epub 2012 Mar 5.

49.

State-of-the art comparability of corrected emission spectra. 2. Field laboratory assessment of calibration performance using spectral fluorescence standards.

Resch-Genger U, Bremser W, Pfeifer D, Spieles M, Hoffmann A, DeRose PC, Zwinkels JC, Gauthier F, Ebert B, Taubert RD, Voigt J, Hollandt J, Macdonald R.

Anal Chem. 2012 May 1;84(9):3899-907. doi: 10.1021/ac203451g. Epub 2012 Apr 16.

PMID:
22376144
50.

State-of-the art comparability of corrected emission spectra. 1. Spectral correction with physical transfer standards and spectral fluorescence standards by expert laboratories.

Resch-Genger U, Bremser W, Pfeifer D, Spieles M, Hoffmann A, DeRose PC, Zwinkels JC, Gauthier F, Ebert B, Taubert RD, Monte C, Voigt J, Hollandt J, Macdonald R.

Anal Chem. 2012 May 1;84(9):3889-98. doi: 10.1021/ac2034503. Epub 2012 Apr 16.

PMID:
22376085

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