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Items: 1 to 50 of 115

1.

Efficacy of bariatric surgery in improving metabolic outcomes in patients with diabetes. A 24-month follow-up study from a single center in the UAE.

Alnageeb H, Abdelgadir E, Khalifa A, Suliman M, Gautam SC, Layani L, Subramaniam S, Bashier A.

Diabetes Metab Syndr Obes. 2018 Sep 3;11:459-467. doi: 10.2147/DMSO.S176761. eCollection 2018.

2.

Anticancer agent pristimerin inhibits IL-2 induced activation of T lymphocytes.

Liu Y, Gao X, Deeb D, Zhang Y, Shaw J, Gautam SC.

J Exp Ther Oncol. 2016 Jul;11(3):181-188.

PMID:
28471123
3.

Mycotoxin verrucarin A inhibits proliferation and induces apoptosis in prostate cancer cells by inhibiting prosurvival Akt/NF-kB/mTOR signaling.

Liu Y, Gao X, Deeb D, Zhang Y, Shaw J, Valeriote FA, Gautam SC.

J Exp Ther Oncol. 2016 Nov;11(4):251-260.

PMID:
27849335
4.
5.

Predictors and Outcomes of Post-Hospitalization Dialysis Dependent Acute Kidney Injury.

Gautam SC, Brooks CH, Balogun RA, Xin W, Ma JZ, Abdel-Rahman EM.

Nephron. 2015;131(3):185-90. doi: 10.1159/000441607. Epub 2015 Nov 3.

PMID:
26524288
6.

CDDO-Me inhibits tumor growth and prevents recurrence of pancreatic ductal adenocarcinoma.

Gao X, Deeb D, Liu Y, Liu P, Zhang Y, Shaw J, Gautam SC.

Int J Oncol. 2015 Dec;47(6):2100-6. doi: 10.3892/ijo.2015.3212. Epub 2015 Oct 19.

7.

Role of telomerase in anticancer activity of pristimerin in prostate cancer cells.

Liu YB, Gao X, Deeb D, Pindolia K, Gautam SC.

J Exp Ther Oncol. 2015;11(1):41-9.

PMID:
26259389
8.

Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.

Deeb D, Gao X, Liu Y, Pindolia K, Gautam SC.

Oncol Rep. 2015 Jul;34(1):518-24. doi: 10.3892/or.2015.3989. Epub 2015 May 19.

9.
10.

Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin.

Liu YB, Gao X, Deeb D, Brigolin C, Zhang Y, Shaw J, Pindolia K, Gautam SC.

Int J Oncol. 2014 Oct;45(4):1735-41. doi: 10.3892/ijo.2014.2561. Epub 2014 Jul 25.

11.

Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways.

Deeb D, Brigolin C, Gao X, Liu Y, Pindolia KR, Gautam SC.

J Carcinog Mutagen. 2014 May 31;5:177.

12.
13.
14.

The seroepidemiology of Haemophilus influenzae type b prior to introduction of an immunization programme in Kathmandu, Nepal.

Marshall AS, Barker CI, Pulickal AS, Kibwana E, Gautam SC, Clutterbuck EA, Thorson SM, Shrestha S, Adhikari N, Pollard AJ, Kelly DF.

PLoS One. 2014 Jan 22;9(1):e85055. doi: 10.1371/journal.pone.0085055. eCollection 2014.

15.

Factors affecting success rate of Advanced Trauma Life Support (ATLS) courses.

Abu-Zidan FM, Mohammad A, Jamal A, Chetty D, Gautam SC, van Dyke M, Branicki FJ.

World J Surg. 2014 Jun;38(6):1405-10. doi: 10.1007/s00268-013-2422-x.

PMID:
24368574
16.

Assessment of characteristics of patient with delirium tremens.

Singh PM, Shrestha DM, Gautam SC, Swar SB, Joshi N.

Nepal Med Coll J. 2012 Sep;14(3):216-8.

PMID:
24047019
17.

Inhibition of telomerase activity by oleanane triterpenoid CDDO-Me in pancreatic cancer cells is ROS-dependent.

Deeb D, Gao X, Liu Y, Varma NR, Arbab AS, Gautam SC.

Molecules. 2013 Mar 13;18(3):3250-65. doi: 10.3390/molecules18033250.

18.

Giant adrenal myelolipoma.

Gautam SC, Raafat H, Sriganesh S, Zaffar I, Olude I, Komolafe F, Qazi F.

Qatar Med J. 2013 Nov 1;2013(1):7-11. doi: 10.5339/qmj.2013.2. eCollection 2013.

19.

ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.

Gao X, Liu Y, Deeb D, Liu P, Liu A, Arbab AS, Gautam SC.

Anticancer Res. 2013 Jan;33(1):215-21.

20.

Bloodstream infection among children presenting to a general hospital outpatient clinic in urban Nepal.

Pradhan R, Shrestha U, Gautam SC, Thorson S, Shrestha K, Yadav BK, Kelly DF, Adhikari N, Pollard AJ, Murdoch DR.

PLoS One. 2012;7(10):e47531. doi: 10.1371/journal.pone.0047531. Epub 2012 Oct 24.

21.

Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt.

Sarveswaran S, Gautam SC, Ghosh J.

Int J Oncol. 2012 Dec;41(6):2191-9. doi: 10.3892/ijo.2012.1664. Epub 2012 Oct 16.

22.
23.

Anticancer agent xanthohumol inhibits IL-2 induced signaling pathways involved in T cell proliferation.

Liu Y, Gao X, Deeb D, Arbab AS, Dulchavsky SA, Gautam SC.

J Exp Ther Oncol. 2012;10(1):1-8.

24.

Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity.

Deeb D, Gao X, Liu Y, Kim SH, Pindolia KR, Arbab AS, Gautam SC.

Biochem Biophys Res Commun. 2012 Jun 15;422(4):561-7. doi: 10.1016/j.bbrc.2012.05.024. Epub 2012 May 16.

25.

Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancer.

Liu Y, Gao X, Deeb D, Arbab AS, Gautam SC.

Molecules. 2012 Dec 11;17(12):14795-809. doi: 10.3390/molecules171214795.

26.

Oleanane triterpenoid CDDO-Me inhibits Akt activity without affecting PDK1 kinase or PP2A phosphatase activity in cancer cells.

Liu Y, Gao X, Deeb D, Gautam SC.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):570-5. doi: 10.1016/j.bbrc.2011.12.007. Epub 2011 Dec 8.

27.

MRI to assess chemoprevention in transgenic adenocarcinoma of mouse prostate (TRAMP).

Arbab AS, Shankar A, Varma NR, Deeb D, Gao X, Iskander AS, Janic B, Ali MM, Gautam SC.

BMC Med Imaging. 2011 Dec 13;11:21. doi: 10.1186/1471-2342-11-21.

28.

Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.

Gao X, Liu Y, Deeb D, Arbab AS, Guo AM, Dulchavsky SA, Gautam SC.

Anticancer Res. 2011 Nov;31(11):3673-81.

29.

Prevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate Cancer.

Gao X, Deeb D, Liu Y, Arbab AS, Divine GW, Dulchavsky SA, Gautam SC.

Cancers (Basel). 2011;3(3):3353-69. doi: 10.3390/cancers3033353.

30.

CDDO-Me: A Novel Synthetic Triterpenoid for the Treatment of Pancreatic Cancer.

Deeb D, Gao X, Arbab AS, Barton K, Dulchavsky SA, Gautam SC.

Cancers (Basel). 2010 Dec;2(4):1779-93. doi: 10.3390/cancers2041779.

31.

Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells.

Gao X, Deeb D, Liu P, Liu Y, Arbab-Ali S, Dulchavsky SA, Gautam SC.

J Exp Ther Oncol. 2011;9(2):119-27.

32.

Synthetic triterpenoid CDDO prevents the progression and metastasis of prostate cancer in TRAMP mice by inhibiting survival signaling.

Deeb D, Gao X, Liu Y, Jiang D, Divine GW, Arbab AS, Dulchavsky SA, Gautam SC.

Carcinogenesis. 2011 May;32(5):757-64. doi: 10.1093/carcin/bgr030. Epub 2011 Feb 16.

33.

Growth inhibitory and apoptosis-inducing effects of xanthohumol, a prenylated chalone present in hops, in human prostate cancer cells.

Deeb D, Gao X, Jiang H, Arbab AS, Dulchavsky SA, Gautam SC.

Anticancer Res. 2010 Sep;30(9):3333-9.

34.
35.

Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells.

Jiang H, Shang X, Wu H, Gautam SC, Al-Holou S, Li C, Kuo J, Zhang L, Chopp M.

J Exp Ther Oncol. 2009;8(1):25-33.

36.

Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism.

Deeb D, Gao X, Jiang H, Janic B, Arbab AS, Rojanasakul Y, Dulchavsky SA, Gautam SC.

Biochem Pharmacol. 2010 Feb 1;79(3):350-60. doi: 10.1016/j.bcp.2009.09.006. Epub 2009 Sep 24.

37.

Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells.

Jiang H, Shang X, Wu H, Huang G, Wang Y, Al-Holou S, Gautam SC, Chopp M.

Neurochem Res. 2010 Jan;35(1):152-61. doi: 10.1007/s11064-009-0040-7. Epub 2009 Aug 15.

38.

Immunomodulatory activity of xanthohumol: inhibition of T cell proliferation, cell-mediated cytotoxicity and Th1 cytokine production through suppression of NF-kappaB.

Gao X, Deeb D, Liu Y, Gautam S, Dulchavsky SA, Gautam SC.

Immunopharmacol Immunotoxicol. 2009;31(3):477-84. doi: 10.1080/08923970902798132.

39.

Therapeutic efficacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer.

Andrzejewski T, Deeb D, Gao X, Danyluk A, Arbab AS, Dulchavsky SA, Gautam SC.

Oncol Res. 2008;17(6):257-67.

PMID:
19192720
40.

Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.

Deeb D, Gao X, Jiang H, Dulchavsky SA, Gautam SC.

Prostate. 2009 Jun 1;69(8):851-60. doi: 10.1002/pros.20937.

41.

Bone marrow-derived stromal cells (BMSCs) interact with fibroblasts in accelerating wound healing.

Dulchavsky D, Gao X, Liu YB, Deeb D, Arbab AS, McIntosh K, Dulchavsky SA, Gautam SC.

J Invest Surg. 2008 Sep-Oct;21(5):270-9. doi: 10.1080/08941930802216831.

PMID:
19160135
42.

Imaging Mouse Prostate Gland by 3 Tesla Clinical MRI System.

Rad AM, Gao X, Deeb D, Gautam SC, Arbab AS.

Open Magn Reson Rev. 2008;1:60-63.

43.

Immunomodulatory activity of synthetic triterpenoids: inhibition of lymphocyte proliferation, cell-mediated cytotoxicity, and cytokine gene expression through suppression of NF-kappaB.

Gao X, Deeb D, Danyluk A, Media J, Liu Y, Dulchavsky SA, Gautam SC.

Immunopharmacol Immunotoxicol. 2008;30(3):581-600. doi: 10.1080/08923970802135559.

PMID:
18608528
44.

Treatment with bone marrow-derived stromal cells accelerates wound healing in diabetic rats.

Kwon DS, Gao X, Liu YB, Dulchavsky DS, Danyluk AL, Bansal M, Chopp M, McIntosh K, Arbab AS, Dulchavsky SA, Gautam SC.

Int Wound J. 2008 Jun;5(3):453-63. doi: 10.1111/j.1742-481X.2007.00408.x.

46.

CDDO-me induces apoptosis and inhibits Akt, mTOR and NF-kappaB signaling proteins in prostate cancer cells.

Deeb D, Gao X, Dulchavsky SA, Gautam SC.

Anticancer Res. 2007 Sep-Oct;27(5A):3035-44.

47.

Immunomodulation by curcumin.

Gautam SC, Gao X, Dulchavsky S.

Adv Exp Med Biol. 2007;595:321-41. Review.

PMID:
17569218
48.
50.

Wound repair by bone marrow stromal cells through growth factor production.

Liu Y, Dulchavsky DS, Gao X, Kwon D, Chopp M, Dulchavsky S, Gautam SC.

J Surg Res. 2006 Dec;136(2):336-41. Epub 2006 Oct 11.

PMID:
17045612

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