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Items: 1 to 50 of 189

1.

High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained.

Bryce NS, Failes TW, Stehn JR, Baker K, Zahler S, Arzhaeva Y, Bischof L, Lyons C, Dedova I, Arndt GM, Gaus K, Goult BT, Hardeman EC, Gunning PW, Lock JG.

Cell Syst. 2019 Sep 30. pii: S2405-4712(19)30310-2. doi: 10.1016/j.cels.2019.09.002. [Epub ahead of print]

PMID:
31606369
2.

Observing the Reversible Single Molecule Electrochemistry of Alexa Fluor 647 Dyes by Total Internal Reflection Fluorescence Microscopy.

Fan S, Webb JEA, Yang Y, Nieves DJ, Gonçales VR, Tran J, Hilzenrat G, Kahram M, Tilley RD, Gaus K, Gooding JJ.

Angew Chem Int Ed Engl. 2019 Oct 7;58(41):14495-14498. doi: 10.1002/anie.201907298. Epub 2019 Aug 30.

PMID:
31418504
3.

Can single molecule localization microscopy detect nanoclusters in T cells?

Feher K, Halstead JM, Goyette J, Gaus K.

Curr Opin Chem Biol. 2019 Aug;51:130-137. doi: 10.1016/j.cbpa.2019.05.019. Epub 2019 Jul 17. Review.

PMID:
31325719
4.

Stoichiometric quantification of spatially dense assemblies with qPAINT.

Baker MAB, Nieves DJ, Hilzenrat G, Berengut JF, Gaus K, Lee LK.

Nanoscale. 2019 Jul 14;11(26):12460-12464. doi: 10.1039/c9nr00472f. Epub 2019 May 23.

PMID:
31120079
5.

Nanopore blockade sensors for ultrasensitive detection of proteins in complex biological samples.

Chuah K, Wu Y, Vivekchand SRC, Gaus K, Reece PJ, Micolich AP, Gooding JJ.

Nat Commun. 2019 May 8;10(1):2109. doi: 10.1038/s41467-019-10147-7.

6.

Phasor histone FLIM-FRET microscopy quantifies spatiotemporal rearrangement of chromatin architecture during the DNA damage response.

Lou J, Scipioni L, Wright BK, Bartolec TK, Zhang J, Masamsetti VP, Gaus K, Gratton E, Cesare AJ, Hinde E.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7323-7332. doi: 10.1073/pnas.1814965116. Epub 2019 Mar 27.

7.

How does T cell receptor clustering impact on signal transduction?

Goyette J, Nieves DJ, Ma Y, Gaus K.

J Cell Sci. 2019 Feb 11;132(4). pii: jcs226423. doi: 10.1242/jcs.226423. Review.

8.

DNA-Based Super-Resolution Microscopy: DNA-PAINT.

Nieves DJ, Gaus K, Baker MAB.

Genes (Basel). 2018 Dec 11;9(12). pii: E621. doi: 10.3390/genes9120621. Review.

9.

Time-Resolved Laurdan Fluorescence Reveals Insights into Membrane Viscosity and Hydration Levels.

Ma Y, Benda A, Kwiatek J, Owen DM, Gaus K.

Biophys J. 2018 Oct 16;115(8):1498-1508. doi: 10.1016/j.bpj.2018.08.041. Epub 2018 Sep 6.

10.

Rod-shaped mesoporous silica nanoparticles for nanomedicine: recent progress and perspectives.

Cong VT, Gaus K, Tilley RD, Gooding JJ.

Expert Opin Drug Deliv. 2018 Sep;15(9):881-892. doi: 10.1080/17425247.2018.1517748. Epub 2018 Sep 7. Review.

PMID:
30173560
11.

Monolayer surface chemistry enables 2-colour single molecule localisation microscopy of adhesive ligands and adhesion proteins.

Lu X, Nicovich PR, Zhao M, Nieves DJ, Mollazade M, Vivekchand SRC, Gaus K, Gooding JJ.

Nat Commun. 2018 Aug 20;9(1):3320. doi: 10.1038/s41467-018-05837-7.

12.

High F-Content Perfluoropolyether-Based Nanoparticles for Targeted Detection of Breast Cancer by 19F Magnetic Resonance and Optical Imaging.

Zhang C, Moonshi SS, Wang W, Ta HT, Han Y, Han FY, Peng H, Král P, Rolfe BE, Gooding JJ, Gaus K, Whittaker AK.

ACS Nano. 2018 Sep 25;12(9):9162-9176. doi: 10.1021/acsnano.8b03726. Epub 2018 Aug 21.

PMID:
30118590
13.

Ultralow- and Low-Background Surfaces for Single-Molecule Localization Microscopy of Multistep Biointerfaces for Single-Molecule Sensing.

Zhao M, Nicovich PR, Janco M, Deng Q, Yang Z, Ma Y, Böcking T, Gaus K, Gooding JJ.

Langmuir. 2018 Aug 28;34(34):10012-10018. doi: 10.1021/acs.langmuir.8b01487. Epub 2018 Aug 15.

PMID:
30067032
14.

Telomere Loop Dynamics in Chromosome End Protection.

Van Ly D, Low RRJ, Frölich S, Bartolec TK, Kafer GR, Pickett HA, Gaus K, Cesare AJ.

Mol Cell. 2018 Aug 16;71(4):510-525.e6. doi: 10.1016/j.molcel.2018.06.025. Epub 2018 Jul 19.

15.

A rapid readout for many single plasmonic nanoparticles using dark-field microscopy and digital color analysis.

Sriram M, Markhali BP, Nicovich PR, Bennett DT, Reece PJ, Brynn Hibbert D, Tilley RD, Gaus K, Vivekchand SRC, Gooding JJ.

Biosens Bioelectron. 2018 Oct 15;117:530-536. doi: 10.1016/j.bios.2018.06.066. Epub 2018 Jul 5.

PMID:
29982124
16.

FSCS Reveals the Complexity of Lipid Domain Dynamics in the Plasma Membrane of Live Cells.

Nicovich PR, Kwiatek JM, Ma Y, Benda A, Gaus K.

Biophys J. 2018 Jun 19;114(12):2855-2864. doi: 10.1016/j.bpj.2018.04.050.

17.

A photoelectrochemical platform for the capture and release of rare single cells.

Parker SG, Yang Y, Ciampi S, Gupta B, Kimpton K, Mansfeld FM, Kavallaris M, Gaus K, Gooding JJ.

Nat Commun. 2018 Jun 12;9(1):2288. doi: 10.1038/s41467-018-04701-y.

18.

A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation.

Compeer EB, Kraus F, Ecker M, Redpath G, Amiezer M, Rother N, Nicovich PR, Kapoor-Kaushik N, Deng Q, Samson GPB, Yang Z, Lou J, Carnell M, Vartoukian H, Gaus K, Rossy J.

Nat Commun. 2018 Apr 23;9(1):1597. doi: 10.1038/s41467-018-04088-w.

19.

High contrast imaging and flexible photomanipulation for quantitative in vivo multiphoton imaging with polygon scanning microscope.

Li Y, Montague SJ, Brüstle A, He X, Gillespie C, Gaus K, Gardiner EE, Lee WM.

J Biophotonics. 2018 Jul;11(7):e201700341. doi: 10.1002/jbio.201700341. Epub 2018 Apr 10.

PMID:
29488344
20.

Introducing Membrane Charge and Membrane Potential to T Cell Signaling.

Ma Y, Poole K, Goyette J, Gaus K.

Front Immunol. 2017 Nov 9;8:1513. doi: 10.3389/fimmu.2017.01513. eCollection 2017. Review.

21.

Real-Time Bioimpedance Sensing of Antifibrotic Drug Action in Primary Human Cells.

Parviz M, Toshniwal P, Viola HM, Hool LC, Fear PMW, Wood FM, Gaus K, Iyer KS, Gooding JJ.

ACS Sens. 2017 Oct 27;2(10):1482-1490. doi: 10.1021/acssensors.7b00442. Epub 2017 Sep 19.

PMID:
28871791
22.

Protease sensing using nontoxic silicon quantum dots.

Cheng X, McVey BFP, Robinson AB, Longatte G, O'Mara PB, Tan VTG, Thordarson P, Tilley RD, Gaus K, Justin Gooding J.

J Biomed Opt. 2017 Aug;22(8):1-7. doi: 10.1117/1.JBO.22.8.087002.

23.

Can single molecule localization microscopy be used to map closely spaced RGD nanodomains?

Mollazade M, Tabarin T, Nicovich PR, Soeriyadi A, Nieves DJ, Gooding JJ, Gaus K.

PLoS One. 2017 Jul 19;12(7):e0180871. doi: 10.1371/journal.pone.0180871. eCollection 2017.

24.

Corrigendum: A FRET sensor enables quantitative measurements of membrane charges in live cells.

Ma Y, Yamamoto Y, Nicovich PR, Goyette J, Rossy J, Gooding JJ, Gaus K.

Nat Biotechnol. 2017 May 9;35(5):481. doi: 10.1038/nbt0517-481e. No abstract available.

PMID:
28486447
25.

An intermolecular FRET sensor detects the dynamics of T cell receptor clustering.

Ma Y, Pandzic E, Nicovich PR, Yamamoto Y, Kwiatek J, Pageon SV, Benda A, Rossy J, Gaus K.

Nat Commun. 2017 Apr 28;8:15100. doi: 10.1038/ncomms15100.

26.

Simultaneous impedance spectroscopy and fluorescence microscopy for the real-time monitoring of the response of cells to drugs.

Parviz M, Gaus K, Gooding JJ.

Chem Sci. 2017 Mar 1;8(3):1831-1840. doi: 10.1039/c6sc05159f. Epub 2017 Jan 3.

27.

NicoLase-An open-source diode laser combiner, fiber launch, and sequencing controller for fluorescence microscopy.

Nicovich PR, Walsh J, Böcking T, Gaus K.

PLoS One. 2017 Mar 16;12(3):e0173879. doi: 10.1371/journal.pone.0173879. eCollection 2017.

28.

A FRET sensor enables quantitative measurements of membrane charges in live cells.

Ma Y, Yamamoto Y, Nicovich PR, Goyette J, Rossy J, Gooding JJ, Gaus K.

Nat Biotechnol. 2017 Apr;35(4):363-370. doi: 10.1038/nbt.3828. Epub 2017 Mar 13. Erratum in: Nat Biotechnol. 2017 May 9;35(5):481.

PMID:
28288102
29.

Zealactones. Novel natural strigolactones from maize.

Charnikhova TV, Gaus K, Lumbroso A, Sanders M, Vincken JP, De Mesmaeker A, Ruyter-Spira CP, Screpanti C, Bouwmeester HJ.

Phytochemistry. 2017 May;137:123-131. doi: 10.1016/j.phytochem.2017.02.010. Epub 2017 Feb 16.

PMID:
28215609
30.

The ATP binding cassette transporter, ABCG1, localizes to cortical actin filaments.

Pandzic E, Gelissen IC, Whan R, Barter PJ, Sviridov D, Gaus K, Rye KA, Cochran BJ.

Sci Rep. 2017 Feb 6;7:42025. doi: 10.1038/srep42025.

31.

Flexible polygon-mirror based laser scanning microscope platform for multiphoton in-vivo imaging.

Li YX, Gautam V, Brüstle A, Cockburn IA, Daria VR, Gillespie C, Gaus K, Alt C, Lee WM.

J Biophotonics. 2017 Nov;10(11):1526-1537. doi: 10.1002/jbio.201600289. Epub 2017 Feb 6.

PMID:
28164461
32.

Turning single-molecule localization microscopy into a quantitative bioanalytical tool.

Nicovich PR, Owen DM, Gaus K.

Nat Protoc. 2017 Mar;12(3):453-460. doi: 10.1038/nprot.2016.166. Epub 2017 Feb 2.

PMID:
28151466
33.

Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility.

Chu EP, Elso CM, Pollock AH, Alsayb MA, Mackin L, Thomas HE, Kay TW, Silveira PA, Mansell AS, Gaus K, Brodnicki TC.

Mol Immunol. 2017 Feb;82:19-33. doi: 10.1016/j.molimm.2016.12.007. Epub 2016 Dec 19.

PMID:
28006656
34.

Towards single molecule biosensors using super-resolution fluorescence microscopy.

Lu X, Nicovich PR, Gaus K, Gooding JJ.

Biosens Bioelectron. 2017 Jul 15;93:1-8. doi: 10.1016/j.bios.2016.10.048. Epub 2016 Oct 24.

PMID:
27829565
35.

Clus-DoC: a combined cluster detection and colocalization analysis for single-molecule localization microscopy data.

Pageon SV, Nicovich PR, Mollazade M, Tabarin T, Gaus K.

Mol Biol Cell. 2016 Nov 7;27(22):3627-3636. Epub 2016 Aug 31.

36.

Pair correlation microscopy reveals the role of nanoparticle shape in intracellular transport and site of drug release.

Hinde E, Thammasiraphop K, Duong HT, Yeow J, Karagoz B, Boyer C, Gooding JJ, Gaus K.

Nat Nanotechnol. 2017 Jan;12(1):81-89. doi: 10.1038/nnano.2016.160. Epub 2016 Sep 12.

PMID:
27618255
37.

Effect of surface chemistry on tropomyosin binding to actin filaments on surfaces.

Nicovich PR, Janco M, Sobey T, Gajwani M, Obeidy P, Whan R, Gaus K, Gunning PW, Coster AC, Böcking T.

Cytoskeleton (Hoboken). 2016 Dec;73(12):729-738. doi: 10.1002/cm.21342. Epub 2016 Nov 23.

PMID:
27783462
38.

Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI.

Pfeiler S, Khandagale AB, Magenau A, Nichols M, Heijnen HF, Rinninger F, Ziegler T, Seveau S, Schubert S, Zahler S, Verschoor A, Latz E, Massberg S, Gaus K, Engelmann B.

Sci Rep. 2016 Oct 3;6:34440. doi: 10.1038/srep34440.

39.

Mechanisms of protein nanoscale clustering.

Goyette J, Gaus K.

Curr Opin Cell Biol. 2017 Feb;44:86-92. doi: 10.1016/j.ceb.2016.09.004. Epub 2016 Sep 22. Review.

PMID:
27666166
40.

New Biological Frontiers Illuminated by Molecular Sensors and Actuators.

Gaus K, Inoue T.

Biophys J. 2016 Sep 20;111(6):E01-E02. doi: 10.1016/j.bpj.2016.08.012. No abstract available.

41.

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination.

Pageon SV, Tabarin T, Yamamoto Y, Ma Y, Nicovich PR, Bridgeman JS, Cohnen A, Benzing C, Gao Y, Crowther MD, Tungatt K, Dolton G, Sewell AK, Price DA, Acuto O, Parton RG, Gooding JJ, Rossy J, Rossjohn J, Gaus K.

Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5454-63. doi: 10.1073/pnas.1607436113. Epub 2016 Aug 29. Erratum in: Proc Natl Acad Sci U S A. 2016 Oct 17;:.

42.

Biologists Wanted: New Fluorescence Fluctuation Tools for Cell Biology.

Gaus K.

Biophys J. 2016 Aug 23;111(4):677-678. doi: 10.1016/j.bpj.2016.07.012. No abstract available.

43.

New Insights into How Trafficking Regulates T Cell Receptor Signaling.

Lou J, Rossy J, Deng Q, Pageon SV, Gaus K.

Front Cell Dev Biol. 2016 Jul 26;4:77. doi: 10.3389/fcell.2016.00077. eCollection 2016. Review.

44.

Measuring membrane association and protein diffusion within membranes with supercritical angle fluorescence microscopy.

Ma Y, Benda A, Nicovich PR, Gaus K.

Biomed Opt Express. 2016 Mar 29;7(4):1561-76. doi: 10.1364/BOE.7.001561. eCollection 2016 Apr 1.

45.

Single-Molecule Sensors: Challenges and Opportunities for Quantitative Analysis.

Gooding JJ, Gaus K.

Angew Chem Int Ed Engl. 2016 Sep 12;55(38):11354-66. doi: 10.1002/anie.201600495. Epub 2016 Jul 22. Review.

PMID:
27444661
46.

Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth.

Vittorio O, Brandl M, Cirillo G, Kimpton K, Hinde E, Gaus K, Yee E, Kumar N, Duong H, Fleming C, Haber M, Norris M, Boyer C, Kavallaris M.

Oncotarget. 2016 Jul 26;7(30):47479-47493. doi: 10.18632/oncotarget.10201.

47.

Prolonged Intake of Dietary Lipids Alters Membrane Structure and T Cell Responses in LDLr-/- Mice.

Pollock AH, Tedla N, Hancock SE, Cornely R, Mitchell TW, Yang Z, Kockx M, Parton RG, Rossy J, Gaus K.

J Immunol. 2016 May 15;196(10):3993-4002. doi: 10.4049/jimmunol.1501261. Epub 2016 Apr 20.

48.

Distinct Mechanisms Regulate Lck Spatial Organization in Activated T Cells.

Kapoor-Kaushik N, Hinde E, Compeer EB, Yamamoto Y, Kraus F, Yang Z, Lou J, Pageon SV, Tabarin T, Gaus K, Rossy J.

Front Immunol. 2016 Mar 8;7:83. doi: 10.3389/fimmu.2016.00083. eCollection 2016.

49.

Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness.

Hinde E, Pandžić E, Yang Z, Ng IH, Jans DA, Bogoyevitch MA, Gratton E, Gaus K.

Nat Commun. 2016 Mar 24;7:11047. doi: 10.1038/ncomms11047.

50.

Activation of Endothelial Nitric Oxide (eNOS) Occurs through Different Membrane Domains in Endothelial Cells.

Tran J, Magenau A, Rodriguez M, Rentero C, Royo T, Enrich C, Thomas SR, Grewal T, Gaus K.

PLoS One. 2016 Mar 15;11(3):e0151556. doi: 10.1371/journal.pone.0151556. eCollection 2016.

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