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Items: 1 to 50 of 81

1.

Automated detection of wrong-drug prescribing errors.

Lambert BL, Galanter W, Liu KL, Falck S, Schiff G, Rash-Foanio C, Schmidt K, Shrestha N, Vaida AJ, Gaunt MJ.

BMJ Qual Saf. 2019 Aug 7. pii: bmjqs-2019-009420. doi: 10.1136/bmjqs-2019-009420. [Epub ahead of print]

2.

Streamlined Synthesis of C(sp3)-Rich N-Heterospirocycles Enabled by Visible-Light-Mediated Photocatalysis.

Flodén NJ, Trowbridge A, Willcox D, Walton SM, Kim Y, Gaunt MJ.

J Am Chem Soc. 2019 May 29;141(21):8426-8430. doi: 10.1021/jacs.9b03372. Epub 2019 May 17.

PMID:
31072095
3.

Carboxylate-Assisted Oxidative Addition to Aminoalkyl PdII Complexes: C(sp3 )-H Arylation of Alkylamines by Distinct PdII /PdIV Pathway.

Whitehurst WG, Blackwell JH, Hermann GN, Gaunt MJ.

Angew Chem Int Ed Engl. 2019 Jul 1;58(27):9054-9059. doi: 10.1002/anie.201902838. Epub 2019 May 24.

PMID:
31042003
4.

Mechanistic investigation into the C(sp3)-H acetoxylation of morpholinones.

Buettner CS, Willcox D, Chappell BGN, Gaunt MJ.

Chem Sci. 2018 Oct 1;10(1):83-89. doi: 10.1039/c8sc03434f. eCollection 2019 Jan 7.

5.

Diastereoselective C-H carbonylative annulation of aliphatic amines: a rapid route to functionalized γ-lactams.

Png ZM, Cabrera-Pardo JR, Peiró Cadahía J, Gaunt MJ.

Chem Sci. 2018 Jul 31;9(39):7628-7633. doi: 10.1039/c8sc02855a. eCollection 2018 Oct 21.

6.

A protein functionalization platform based on selective reactions at methionine residues.

Taylor MT, Nelson JE, Suero MG, Gaunt MJ.

Nature. 2018 Oct;562(7728):563-568. doi: 10.1038/s41586-018-0608-y. Epub 2018 Oct 15.

7.

Multicomponent synthesis of tertiary alkylamines by photocatalytic olefin-hydroaminoalkylation.

Trowbridge A, Reich D, Gaunt MJ.

Nature. 2018 Sep;561(7724):522-527. doi: 10.1038/s41586-018-0537-9. Epub 2018 Sep 26.

PMID:
30258135
8.

Identifying health information technology related safety event reports from patient safety event report databases.

Fong A, Adams KT, Gaunt MJ, Howe JL, Kellogg KM, Ratwani RM.

J Biomed Inform. 2018 Oct;86:135-142. doi: 10.1016/j.jbi.2018.09.007. Epub 2018 Sep 10.

PMID:
30213556
9.

The α-tertiary amine motif drives remarkable selectivity for Pd-catalyzed carbonylation of β-methylene C-H bonds.

Hogg KF, Trowbridge A, Alvarez-Pérez A, Gaunt MJ.

Chem Sci. 2017 Dec 1;8(12):8198-8203. doi: 10.1039/c7sc03876c. Epub 2017 Oct 9.

10.

Selective Reductive Elimination at Alkyl Palladium(IV) by Dissociative Ligand Ionization: Catalytic C(sp3 )-H Amination to Azetidines.

Nappi M, He C, Whitehurst WG, Chappell BGN, Gaunt MJ.

Angew Chem Int Ed Engl. 2018 Mar 12;57(12):3178-3182. doi: 10.1002/anie.201800519. Epub 2018 Feb 22.

PMID:
29380496
11.

Selective Palladium(II)-Catalyzed Carbonylation of Methylene β-C-H Bonds in Aliphatic Amines.

Cabrera-Pardo JR, Trowbridge A, Nappi M, Ozaki K, Gaunt MJ.

Angew Chem Int Ed Engl. 2017 Sep 18;56(39):11958-11962. doi: 10.1002/anie.201706303. Epub 2017 Aug 21.

PMID:
28707312
12.

Enantioselective Copper-Catalyzed Arylation-Driven Semipinacol Rearrangement of Tertiary Allylic Alcohols with Diaryliodonium Salts.

Lukamto DH, Gaunt MJ.

J Am Chem Soc. 2017 Jul 12;139(27):9160-9163. doi: 10.1021/jacs.7b05340. Epub 2017 Jun 29.

PMID:
28640609
13.

Correction to "Palladium-Catalyzed Enantioselective C-H Activation of Aliphatic Amines Using Chiral Anionic BINOL-Phosphoric Acid Ligands".

Smalley AP, Cuthbertson JD, Gaunt MJ.

J Am Chem Soc. 2017 Jun 14;139(23):8052. doi: 10.1021/jacs.7b05390. Epub 2017 May 31. No abstract available.

PMID:
28562034
14.

Cobalt-catalysed C-H carbonylative cyclisation of aliphatic amides.

Williamson P, Galván A, Gaunt MJ.

Chem Sci. 2017 Apr 1;8(4):2588-2591. doi: 10.1039/c6sc05581h. Epub 2017 Jan 10.

15.

Ligand-assisted palladium-catalyzed C-H alkenylation of aliphatic amines for the synthesis of functionalized pyrrolidines.

He C, Gaunt MJ.

Chem Sci. 2017 May 1;8(5):3586-3592. doi: 10.1039/c7sc00468k. Epub 2017 Feb 23.

16.

Palladium-Catalyzed Enantioselective C-H Activation of Aliphatic Amines Using Chiral Anionic BINOL-Phosphoric Acid Ligands.

Smalley AP, Cuthbertson JD, Gaunt MJ.

J Am Chem Soc. 2017 Feb 1;139(4):1412-1415. doi: 10.1021/jacs.6b12234. Epub 2017 Jan 18. Erratum in: J Am Chem Soc. 2017 Jun 14;139(23 ):8052.

PMID:
28064488
17.

A general catalytic β-C-H carbonylation of aliphatic amines to β-lactams.

Willcox D, Chappell BG, Hogg KF, Calleja J, Smalley AP, Gaunt MJ.

Science. 2016 Nov 18;354(6314):851-857.

PMID:
27856900
18.

Characterizing the pain score trajectories of hospitalized adult medical and surgical patients: a retrospective cohort study.

Kannampallil T, Galanter WL, Falck S, Gaunt MJ, Gibbons RD, McNutt R, Odwazny R, Schiff G, Vaida AJ, Wilkie DJ, Lambert BL.

Pain. 2016 Dec;157(12):2739-2746.

19.
20.

Continuous-Flow Synthesis and Derivatization of Aziridines through Palladium-Catalyzed C(sp(3) )-H Activation.

Zakrzewski J, Smalley AP, Kabeshov MA, Gaunt MJ, Lapkin AA.

Angew Chem Int Ed Engl. 2016 Jul 25;55(31):8878-83. doi: 10.1002/anie.201602483. Epub 2016 Jun 15.

21.

Avoiding Medication Errors: Reducing Harm in Residents Using Oral Anticoagulants.

Grissinger M, Gaunt MJ, Rich DS.

Consult Pharm. 2016;31(6):294-303. doi: 10.4140/TCP.n.2016.294.

PMID:
27250070
22.

Cognitive tests predict real-world errors: the relationship between drug name confusion rates in laboratory-based memory and perception tests and corresponding error rates in large pharmacy chains.

Schroeder SR, Salomon MM, Galanter WL, Schiff GD, Vaida AJ, Gaunt MJ, Bryson ML, Rash C, Falck S, Lambert BL.

BMJ Qual Saf. 2017 May;26(5):395-407. doi: 10.1136/bmjqs-2015-005099. Epub 2016 May 18.

23.

The total synthesis of K-252c (staurosporinone) via a sequential C-H functionalisation strategy.

Fox JC, Gilligan RE, Pitts AK, Bennett HR, Gaunt MJ.

Chem Sci. 2016 Apr 21;7(4):2706-2710. doi: 10.1039/c5sc04399a. Epub 2016 Jan 21.

24.

A steric tethering approach enables palladium-catalysed C-H activation of primary amino alcohols.

Calleja J, Pla D, Gorman TW, Domingo V, Haffemayer B, Gaunt MJ.

Nat Chem. 2015 Dec;7(12):1009-16. doi: 10.1038/nchem.2367. Epub 2015 Nov 2.

PMID:
26587717
25.

Ligand-Enabled Catalytic C-H Arylation of Aliphatic Amines by a Four-Membered-Ring Cyclopalladation Pathway.

He C, Gaunt MJ.

Angew Chem Int Ed Engl. 2015 Dec 21;54(52):15840-4. doi: 10.1002/anie.201508912. Epub 2015 Nov 5.

PMID:
26537617
26.

Mechanistic Insights into the Palladium-Catalyzed Aziridination of Aliphatic Amines by C-H Activation.

Smalley AP, Gaunt MJ.

J Am Chem Soc. 2015 Aug 26;137(33):10632-41. doi: 10.1021/jacs.5b05529. Epub 2015 Aug 14.

PMID:
26247373
27.

Callipeltosides A, B and C: Total Syntheses and Structural Confirmation.

Frost JR, Pearson CM, Snaddon TN, Booth RA, Turner RM, Gold J, Shaw DM, Gaunt MJ, Ley SV.

Chemistry. 2015 Sep 14;21(38):13261-77. doi: 10.1002/chem.201501877. Epub 2015 Jul 31.

28.

Enantioselective and Regiodivergent Copper-Catalyzed Electrophilic Arylation of Allylic Amides with Diaryliodonium Salts.

Cahard E, Male HP, Tissot M, Gaunt MJ.

J Am Chem Soc. 2015 Jul 1;137(25):7986-9. doi: 10.1021/jacs.5b03937. Epub 2015 Jun 19.

29.

Copper-Catalyzed Oxy-Alkenylation of Homoallylic Alcohols to Generate Functional syn-1,3-Diol Derivatives.

Holt D, Gaunt MJ.

Angew Chem Int Ed Engl. 2015 Jun 26;54(27):7857-61. doi: 10.1002/anie.201501995. Epub 2015 May 27.

PMID:
26012522
30.

A concise and scalable strategy for the total synthesis of dictyodendrin B based on sequential C-H functionalization.

Pitts AK, O'Hara F, Snell RH, Gaunt MJ.

Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5451-5. doi: 10.1002/anie.201500067. Epub 2015 Feb 23.

PMID:
25706658
31.

A counteranion triggered arylation strategy using diaryliodonium fluorides.

Chan L, McNally A, Toh QY, Mendoza A, Gaunt MJ.

Chem Sci. 2015 Feb 1;6(2):1277-1281. doi: 10.1039/c4sc02856b. Epub 2014 Nov 12.

32.

Gram-scale enantioselective formal synthesis of morphine through an ortho-para oxidative phenolic coupling strategy.

Tissot M, Phipps RJ, Lucas C, Leon RM, Pace RD, Ngouansavanh T, Gaunt MJ.

Angew Chem Int Ed Engl. 2014 Dec 1;53(49):13498-501. doi: 10.1002/anie.201408435. Epub 2014 Oct 6.

PMID:
25288124
33.

Cu-catalyzed cascades to carbocycles: union of diaryliodonium salts with alkenes or alkynes exploiting remote carbocations.

Zhang F, Das S, Walkinshaw AJ, Casitas A, Taylor M, Suero MG, Gaunt MJ.

J Am Chem Soc. 2014 Jun 25;136(25):8851-4. doi: 10.1021/ja504361y. Epub 2014 Jun 12.

PMID:
24905079
34.

Palladium-catalysed C-H activation of aliphatic amines to give strained nitrogen heterocycles.

McNally A, Haffemayer B, Collins BS, Gaunt MJ.

Nature. 2014 Jun 5;510(7503):129-33. doi: 10.1038/nature13389. Epub 2014 May 28. Erratum in: Nature. 2014 Aug 21;512(7514):338.

PMID:
24870240
35.

Reducing harm in patients using insulin.

Grissinger M, Gaunt MJ.

Consult Pharm. 2014;29(5):290-302. doi: 10.4140/TCP.n.2014.290.

PMID:
24849687
36.

Copper-catalyzed carboarylation of alkynes via vinyl cations.

Walkinshaw AJ, Xu W, Suero MG, Gaunt MJ.

J Am Chem Soc. 2013 Aug 28;135(34):12532-5. doi: 10.1021/ja405972h. Epub 2013 Aug 15.

PMID:
23947578
37.

Copper-catalyzed intramolecular electrophilic carbofunctionalization of allylic amides.

Cahard E, Bremeyer N, Gaunt MJ.

Angew Chem Int Ed Engl. 2013 Aug 26;52(35):9284-8. doi: 10.1002/anie.201303724. Epub 2013 Jul 15. No abstract available.

PMID:
23857874
38.

Copper-catalyzed arylative Meyer-Schuster rearrangement of propargylic alcohols to complex enones using diaryliodonium salts.

Collins BS, Suero MG, Gaunt MJ.

Angew Chem Int Ed Engl. 2013 May 27;52(22):5799-802. doi: 10.1002/anie.201301529. Epub 2013 Apr 22. No abstract available.

PMID:
23610012
39.

Copper-catalyzed electrophilic carbofunctionalization of alkynes to highly functionalized tetrasubstituted alkenes.

Suero MG, Bayle ED, Collins BS, Gaunt MJ.

J Am Chem Soc. 2013 Apr 10;135(14):5332-5. doi: 10.1021/ja401840j. Epub 2013 Mar 29.

PMID:
23521626
40.

Organocatalytic C-H bond arylation of aldehydes to bis-heteroaryl ketones.

Toh QY, McNally A, Vera S, Erdmann N, Gaunt MJ.

J Am Chem Soc. 2013 Mar 13;135(10):3772-5. doi: 10.1021/ja400051d. Epub 2013 Feb 27.

PMID:
23445238
41.

Chemical synthesis of Aspidosperma alkaloids inspired by the reverse of the biosynthesis of the rhazinilam family of natural products.

McMurray L, Beck EM, Gaunt MJ.

Angew Chem Int Ed Engl. 2012 Sep 10;51(37):9288-91. doi: 10.1002/anie.201204151. Epub 2012 Aug 22. No abstract available.

PMID:
22915344
42.

Copper-catalyzed alkene arylation with diaryliodonium salts.

Phipps RJ, McMurray L, Ritter S, Duong HA, Gaunt MJ.

J Am Chem Soc. 2012 Jul 4;134(26):10773-6. doi: 10.1021/ja3039807. Epub 2012 Jun 19.

PMID:
22712572
43.

Enantioselective α-arylation of N-acyloxazolidinones with copper(II)-bisoxazoline catalysts and diaryliodonium salts.

Bigot A, Williamson AE, Gaunt MJ.

J Am Chem Soc. 2011 Sep 7;133(35):13778-81. doi: 10.1021/ja206047h. Epub 2011 Aug 17.

PMID:
21848264
44.

Reducing patient harm with the use of opioid oral solutions.

Grissinger M, Gaunt MJ.

Consult Pharm. 2011 Jun;26(6):380-8. doi: 10.4140/TCP.n.2011.380.

PMID:
21628137
45.

Recent developments in natural product synthesis using metal-catalysed C-H bond functionalisation.

McMurray L, O'Hara F, Gaunt MJ.

Chem Soc Rev. 2011 Apr;40(4):1885-98. doi: 10.1039/c1cs15013h. Epub 2011 Mar 10. Review.

PMID:
21390391
46.

Palladium(II)-catalyzed C-H bond arylation of electron-deficient arenes at room temperature.

Tredwell MJ, Gulias M, Bremeyer NG, Johansson CC, Collins BS, Gaunt MJ.

Angew Chem Int Ed Engl. 2011 Feb 1;50(5):1076-9. doi: 10.1002/anie.201005990. Epub 2010 Dec 22. No abstract available.

PMID:
21268198
47.

Mapping a Large Patient Safety Database to the 2005 Patient Safety Event Taxonomy.

Clarke JR, Johnston J, Davis M, Augustine AJ, Grissinger M, Gaunt MJ, Cohen H, Marella W.

In: Henriksen K, Battles JB, Keyes MA, Grady ML, editors. Advances in Patient Safety: New Directions and Alternative Approaches (Vol. 1: Assessment). Rockville (MD): Agency for Healthcare Research and Quality; 2008 Aug.

48.

A highly para-selective copper(II)-catalyzed direct arylation of aniline and phenol derivatives.

Ciana CL, Phipps RJ, Brandt JR, Meyer FM, Gaunt MJ.

Angew Chem Int Ed Engl. 2011 Jan 10;50(2):458-62. doi: 10.1002/anie.201004703. No abstract available.

PMID:
21140387
49.

Copper(II)-catalyzed meta-selective direct arylation of α-aryl carbonyl compounds.

Duong HA, Gilligan RE, Cooke ML, Phipps RJ, Gaunt MJ.

Angew Chem Int Ed Engl. 2011 Jan 10;50(2):463-6. doi: 10.1002/anie.201004704. Epub 2010 Oct 22. No abstract available.

PMID:
20967917
50.

Reducing patient harm with the use of fentanyl transdermal system.

Grissinger M, Gaunt MJ.

Consult Pharm. 2009 Dec;24(12):864-72.

PMID:
20156000

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