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Items: 1 to 50 of 273

1.

Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score.

Carbone M, Nardi A, Flack S, Carpino G, Varvaropoulou N, Gavrila C, Spicer A, Badrock J, Bernuzzi F, Cardinale V, Ainsworth HF, Heneghan MA, Thorburn D, Bathgate A, Jones R, Neuberger JM, Battezzati PM, Zuin M, Taylor-Robinson S, Donato MF, Kirby J, Mitchell-Thain R, Floreani A, Sampaziotis F, Muratori L, Alvaro D, Marzioni M, Miele L, Marra F, Giannini E, Gaudio E, Ronca V, Bonato G, Cristoferi L, Malinverno F, Gerussi A, Stocken DD, Cordell HJ, Hirschfield GM, Alexander GJ, Sandford RN, Jones DE, Invernizzi P, Mells GF; Italian PBC Study Group and the UK–PBC Consortium.

Lancet Gastroenterol Hepatol. 2018 Jul 12. pii: S2468-1253(18)30163-8. doi: 10.1016/S2468-1253(18)30163-8. [Epub ahead of print]

PMID:
30017646
2.

Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes.

Zhou T, Wu N, Meng F, Venter J, Giang TK, Francis H, Kyritsi K, Wu C, Franchitto A, Alvaro D, Marzioni M, Onori P, Mancinelli R, Gaudio E, Glaser S, Alpini G.

Lab Invest. 2018 Jul 5. doi: 10.1038/s41374-018-0093-9. [Epub ahead of print]

PMID:
29977037
3.

The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells.

D'Agostino S, Lanzillotta D, Varano M, Botta C, Baldrini A, Bilotta A, Scalise S, Dattilo V, Amato R, Gaudio E, Paduano F, Palmieri C, Iuliano R, Perrotti N, Indiveri C, Fusco A, Gaspari M, Trapasso F.

Oncotarget. 2018 May 4;9(34):23334-23348. doi: 10.18632/oncotarget.25101. eCollection 2018 May 4.

4.

Immunolocalization of Advanced Glycation End Products, Mitogen Activated Protein Kinases, and Transforming Growth Factor-β/Smads in Pelvic Organ Prolapse.

Vetuschi A, Pompili S, Gallone A, D'Alfonso A, Carbone MG, Carta G, Festuccia C, Gaudio E, Colapietro A, Sferra R.

J Histochem Cytochem. 2018 May 1:22155418772798. doi: 10.1369/0022155418772798. [Epub ahead of print]

PMID:
29737911
5.

Liquid Biopsy in Rare Cancers: Lessons from Hemangiopericytoma.

Nicolazzo C, Colangelo L, Corsi A, Carpino G, Gradilone A, Sonato C, Raimondi C, Gaudio E, Gazzaniga P, Gianni W.

Anal Cell Pathol (Amst). 2018 Mar 7;2018:9718585. doi: 10.1155/2018/9718585. eCollection 2018.

6.

Alfaxalone anaesthesia in Lemur catta following dexmedetomidine-butorphanol-midazolam sedation.

Gaudio E, Voltan L, De Benedictis GM.

Vet Anaesth Analg. 2018 May;45(3):351-356. doi: 10.1016/j.vaa.2018.01.004. Epub 2018 Feb 3.

PMID:
29625917
7.

Role of lactoferrin and its receptors on biliary epithelium.

Mancinelli R, Olivero F, Carpino G, Overi D, Rosa L, Lepanto MS, Cutone A, Franchitto A, Alpini G, Onori P, Valenti P, Gaudio E.

Biometals. 2018 Jun;31(3):369-379. doi: 10.1007/s10534-018-0094-6. Epub 2018 Mar 17.

PMID:
29550924
8.

Overexpression of the Vitronectin V10 Subunit in Patients with Nonalcoholic Steatohepatitis: Implications for Noninvasive Diagnosis of NASH.

Del Ben M, Overi D, Polimeni L, Carpino G, Labbadia G, Baratta F, Pastori D, Noce V, Gaudio E, Angelico F, Mancone C.

Int J Mol Sci. 2018 Feb 18;19(2). pii: E603. doi: 10.3390/ijms19020603.

9.

Hepatic Stem/Progenitor Cell Activation Differs between Primary Sclerosing and Primary Biliary Cholangitis.

Carpino G, Cardinale V, Folseraas T, Overi D, Floreani A, Franchitto A, Onori P, Cazzagon N, Berloco PB, Karlsen TH, Alvaro D, Gaudio E.

Am J Pathol. 2018 Mar;188(3):627-639. doi: 10.1016/j.ajpath.2017.11.010. Epub 2017 Dec 15.

PMID:
29248458
10.

PD-L1 and epithelial-mesenchymal transition in circulating tumor cells from non-small cell lung cancer patients: A molecular shield to evade immune system?

Raimondi C, Carpino G, Nicolazzo C, Gradilone A, Gianni W, Gelibter A, Gaudio E, Cortesi E, Gazzaniga P.

Oncoimmunology. 2017 Apr 20;6(12):e1315488. doi: 10.1080/2162402X.2017.1315488. eCollection 2017.

11.

Laparoscopic Sleeve Gastrectomy Improves Nonalcoholic Fatty Liver Disease-Related Liver Damage in Adolescents by Reshaping Cellular Interactions and Hepatic Adipocytokine Production.

Nobili V, Carpino G, De Peppo F, Caccamo R, Mosca A, Romito I, Overi D, Franchitto A, Onori P, Alisi A, Gaudio E.

J Pediatr. 2018 Mar;194:100-108.e3. doi: 10.1016/j.jpeds.2017.10.036. Epub 2017 Dec 1.

PMID:
29198531
12.

PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress.

Carpino G, Pastori D, Baratta F, Overi D, Labbadia G, Polimeni L, Di Costanzo A, Pannitteri G, Carnevale R, Del Ben M, Arca M, Violi F, Angelico F, Gaudio E.

Sci Rep. 2017 Nov 17;7(1):15756. doi: 10.1038/s41598-017-15943-z.

13.

Endodontic treatment of canine teeth in a cynomolgus monkey ( Macaca fascicularis).

Facchini C, Iacopetti I, Gaudio E, Zotti A, Boldrin M, Fante F, Mutinelli F, Cozzi E, De Benedictis GM.

Lab Anim. 2018 Jun;52(3):308-312. doi: 10.1177/0023677217737568. Epub 2017 Nov 10.

PMID:
29126360
14.

Activation of Fas/FasL pathway and the role of c-FLIP in primary culture of human cholangiocarcinoma cells.

Carnevale G, Carpino G, Cardinale V, Pisciotta A, Riccio M, Bertoni L, Gibellini L, De Biasi S, Nevi L, Costantini D, Overi D, Cossarizza A, de Pol A, Gaudio E, Alvaro D.

Sci Rep. 2017 Oct 31;7(1):14419. doi: 10.1038/s41598-017-14838-3.

15.

PQR309 Is a Novel Dual PI3K/mTOR Inhibitor with Preclinical Antitumor Activity in Lymphomas as a Single Agent and in Combination Therapy.

Tarantelli C, Gaudio E, Arribas AJ, Kwee I, Hillmann P, Rinaldi A, Cascione L, Spriano F, Bernasconi E, Guidetti F, Carrassa L, Pittau RB, Beaufils F, Ritschard R, Rageot D, Sele A, Dossena B, Rossi FM, Zucchetto A, Taborelli M, Gattei V, Rossi D, Stathis A, Stussi G, Broggini M, Wymann MP, Wicki A, Zucca E, Cmiljanovic V, Fabbro D, Bertoni F.

Clin Cancer Res. 2018 Jan 1;24(1):120-129. doi: 10.1158/1078-0432.CCR-17-1041. Epub 2017 Oct 24.

PMID:
29066507
16.

TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line.

Gaudio E, Paduano F, Pinton S, D'Agostino S, Rocca R, Costa G, Ngankeu A, Aqeilan RI, Croce CM, Bertoni F, Alcaro S, Trapasso F.

Br J Haematol. 2017 Oct 19. doi: 10.1111/bjh.14989. [Epub ahead of print] No abstract available.

PMID:
29048125
17.

Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.

Trapasso F, Pichiorri F, Gaspari M, Palumbo T, Aqeilan RI, Gaudio E, Okumura H, Iuliano R, Di Leva G, Fabbri M, Birk DE, Raso C, Green-Church K, Spagnoli LG, Venuta S, Huebner K, Croce CM.

J Biol Chem. 2017 Aug 25;292(34):14279. doi: 10.1074/jbc.A117.709062. No abstract available.

18.

The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study.

Sferra R, Pompili S, Festuccia C, Marampon F, Gravina GL, Ventura L, Di Cesare E, Cicchinelli S, Gaudio E, Vetuschi A.

Eur J Histochem. 2017 May 16;61(2):2732. doi: 10.4081/ejh.2017.2732.

19.

Cholangiocytes: Cell transplantation.

Ridola L, Bragazzi MC, Cardinale V, Carpino G, Gaudio E, Alvaro D.

Biochim Biophys Acta. 2018 Apr;1864(4 Pt B):1516-1523. doi: 10.1016/j.bbadis.2017.07.016. Epub 2017 Jul 19. Review.

PMID:
28735098
20.

Cryopreservation protocol for human biliary tree stem/progenitors, hepatic and pancreatic precursors.

Nevi L, Cardinale V, Carpino G, Costantini D, Di Matteo S, Cantafora A, Melandro F, Brunelli R, Bastianelli C, Aliberti C, Monti M, Bosco D, Berloco PB, Panici PB, Reid L, Gaudio E, Alvaro D.

Sci Rep. 2017 Jul 20;7(1):6080. doi: 10.1038/s41598-017-05858-0.

21.

Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma.

Bernasconi E, Gaudio E, Lejeune P, Tarantelli C, Cascione L, Kwee I, Spriano F, Rinaldi A, Mensah AA, Chung E, Stathis A, Siegel S, Schmees N, Ocker M, Zucca E, Haendler B, Bertoni F.

Br J Haematol. 2017 Sep;178(6):936-948. doi: 10.1111/bjh.14803. Epub 2017 Jun 27.

PMID:
28653353
22.

Prolonged darkness reduces liver fibrosis in a mouse model of primary sclerosing cholangitis by miR-200b down-regulation.

Wu N, Meng F, Zhou T, Han Y, Kennedy L, Venter J, Francis H, DeMorrow S, Onori P, Invernizzi P, Bernuzzi F, Mancinelli R, Gaudio E, Franchitto A, Glaser S, Alpini G.

FASEB J. 2017 Oct;31(10):4305-4324. doi: 10.1096/fj.201700097R. Epub 2017 Jun 20.

PMID:
28634212
23.

Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b.

Kyritsi K, Meng F, Zhou T, Wu N, Venter J, Francis H, Kennedy L, Onori P, Franchitto A, Bernuzzi F, Invernizzi P, McDaniel K, Mancinelli R, Alvaro D, Gaudio E, Alpini G, Glaser S.

Am J Pathol. 2017 Jul;187(7):1551-1565. doi: 10.1016/j.ajpath.2017.03.013. Epub 2017 May 12.

24.

Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride-induced liver cirrhosis.

Giusto M, Barberi L, Di Sario F, Rizzuto E, Nicoletti C, Ascenzi F, Renzi A, Caporaso N, D'Argenio G, Gaudio E, Musarò A, Merli M.

Physiol Rep. 2017 Apr;5(7). pii: e13153. doi: 10.14814/phy2.13153.

25.

Hyaluronan coating improves liver engraftment of transplanted human biliary tree stem/progenitor cells.

Nevi L, Carpino G, Costantini D, Cardinale V, Riccioni O, Di Matteo S, Melandro F, Berloco PB, Reid L, Gaudio E, Alvaro D.

Stem Cell Res Ther. 2017 Mar 20;8(1):68. doi: 10.1186/s13287-017-0492-7.

26.

Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis.

Di Gregorio J, Sferra R, Speca S, Vetuschi A, Dubuquoy C, Desreumaux P, Pompili S, Cristiano L, Gaudio E, Flati V, Latella G.

PLoS One. 2017 Feb 16;12(2):e0171093. doi: 10.1371/journal.pone.0171093. eCollection 2017.

27.

The Role of Tissue Macrophage-Mediated Inflammation on NAFLD Pathogenesis and Its Clinical Implications.

Alisi A, Carpino G, Oliveira FL, Panera N, Nobili V, Gaudio E.

Mediators Inflamm. 2017;2017:8162421. doi: 10.1155/2017/8162421. Epub 2017 Jan 1. Review.

28.

Cell sources for regenerative medicine of the liver and endoderm organs: strategies and perspectives.

Carpino G, Gaudio E.

Stem Cell Investig. 2016 Dec 9;3:91. doi: 10.21037/sci.2016.11.11. eCollection 2016. No abstract available.

29.

A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis.

Bilotta A, Dattilo V, D'Agostino S, Belviso S, Scalise S, Bilotta M, Gaudio E, Paduano F, Perrotti N, Florio T, Fusco A, Iuliano R, Trapasso F.

Oncotarget. 2017 Feb 7;8(6):10091-10102. doi: 10.18632/oncotarget.14350.

30.

Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage.

Marampon F, Gravina GL, Ju X, Vetuschi A, Sferra R, Casimiro MC, Pompili S, Festuccia C, Colapietro A, Gaudio E, Di Cesare E, Tombolini V, Pestell RG.

Oncotarget. 2016 Sep 27;7(39):64526. doi: 10.18632/oncotarget.12267. No abstract available.

31.

Docosahexanoic Acid Plus Vitamin D Treatment Improves Features of NAFLD in Children with Serum Vitamin D Deficiency: Results from a Single Centre Trial.

Della Corte C, Carpino G, De Vito R, De Stefanis C, Alisi A, Cianfarani S, Overi D, Mosca A, Stronati L, Cucchiara S, Raponi M, Gaudio E, Byrne CD, Nobili V.

PLoS One. 2016 Dec 15;11(12):e0168216. doi: 10.1371/journal.pone.0168216. eCollection 2016.

32.

Expression of pro-fibrotic and anti-fibrotic molecules in dimethylnitrosamine-induced hepatic fibrosis.

Sferra R, Vetuschi A, Pompili S, Gaudio E, Speca S, Latella G.

Pathol Res Pract. 2017 Jan;213(1):58-65. doi: 10.1016/j.prp.2016.11.004. Epub 2016 Nov 11.

PMID:
27894619
33.

The Fhit protein: an opportunity to overcome chemoresistance.

Gaudio E, Paduano F, Croce CM, Trapasso F.

Aging (Albany NY). 2016 Nov 12;8(11):3147-3150. doi: 10.18632/aging.101123. No abstract available.

34.

Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease.

Mancinelli R, Franchitto A, Glaser S, Vetuschi A, Venter J, Sferra R, Pannarale L, Olivero F, Carpino G, Alpini G, Onori P, Gaudio E.

Lab Invest. 2016 Nov;96(11):1147-1155. doi: 10.1038/labinvest.2016.93. Epub 2016 Aug 29.

35.

Forkhead box A2 regulates biliary heterogeneity and senescence during cholestatic liver injury in mice‡.

McDaniel K, Meng F, Wu N, Sato K, Venter J, Bernuzzi F, Invernizzi P, Zhou T, Kyritsi K, Wan Y, Huang Q, Onori P, Francis H, Gaudio E, Glaser S, Alpini G.

Hepatology. 2017 Feb;65(2):544-559. doi: 10.1002/hep.28831. Epub 2016 Nov 5.

36.

Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma.

Gaudio E, Tarantelli C, Ponzoni M, Odore E, Rezai K, Bernasconi E, Cascione L, Rinaldi A, Stathis A, Riveiro E, Cvitkovic E, Zucca E, Bertoni F.

Oncotarget. 2016 Sep 6;7(36):58142-58147. doi: 10.18632/oncotarget.10983.

37.

Human biliary tree stem/progenitor cells immunomodulation: Role of hepatocyte growth factor.

Maraldi T, Guida M, Beretti F, Resca E, Carpino G, Cardinale V, Gentile R, Ardizzoni A, Murgia A, Alvaro D, Gaudio E, De Pol A.

Hepatol Res. 2017 Apr;47(5):465-479. doi: 10.1111/hepr.12772. Epub 2016 Aug 16.

PMID:
27381820
38.

Macrophage Activation in Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Correlates with Hepatic Progenitor Cell Response via Wnt3a Pathway.

Carpino G, Nobili V, Renzi A, De Stefanis C, Stronati L, Franchitto A, Alisi A, Onori P, De Vito R, Alpini G, Gaudio E.

PLoS One. 2016 Jun 16;11(6):e0157246. doi: 10.1371/journal.pone.0157246. eCollection 2016.

39.

Assessment of the Antiproliferative Activity of a BET Bromodomain Inhibitor as Single Agent and in Combination in Non-Hodgkin Lymphoma Cell Lines.

Bernasconi E, Gaudio E, Kwee I, Bertoni F.

Methods Mol Biol. 2016;1436:305-12. doi: 10.1007/978-1-4939-3667-0_20.

PMID:
27246223
40.

A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells.

Gaudio E, Paduano F, Ngankeu A, Ortuso F, Lovat F, Pinton S, D'Agostino S, Zanesi N, Aqeilan RI, Campiglia P, Novellino E, Alcaro S, Croce CM, Trapasso F.

Oncotarget. 2016 May 24;7(21):29927-36. doi: 10.18632/oncotarget.9179.

41.

The secretin/secretin receptor axis modulates liver fibrosis through changes in transforming growth factor-β1 biliary secretion in mice.

Wu N, Meng F, Invernizzi P, Bernuzzi F, Venter J, Standeford H, Onori P, Marzioni M, Alvaro D, Franchitto A, Gaudio E, Glaser S, Alpini G.

Hepatology. 2016 Sep;64(3):865-79. doi: 10.1002/hep.28622. Epub 2016 Jun 11.

42.

Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).

Banales JM, Cardinale V, Carpino G, Marzioni M, Andersen JB, Invernizzi P, Lind GE, Folseraas T, Forbes SJ, Fouassier L, Geier A, Calvisi DF, Mertens JC, Trauner M, Benedetti A, Maroni L, Vaquero J, Macias RI, Raggi C, Perugorria MJ, Gaudio E, Boberg KM, Marin JJ, Alvaro D.

Nat Rev Gastroenterol Hepatol. 2016 May;13(5):261-80. doi: 10.1038/nrgastro.2016.51. Epub 2016 Apr 20.

43.

Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson's Disease.

Vivacqua G, Latorre A, Suppa A, Nardi M, Pietracupa S, Mancinelli R, Fabbrini G, Colosimo C, Gaudio E, Berardelli A.

PLoS One. 2016 Mar 24;11(3):e0151156. doi: 10.1371/journal.pone.0151156. eCollection 2016.

44.

Liver Capsule: Biliary Tree Stem Cell Subpopulations.

Alvaro D, Gaudio E.

Hepatology. 2016 Aug;64(2):644. doi: 10.1002/hep.28546. Epub 2016 Apr 15. Review. No abstract available.

PMID:
26973016
45.

Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse.

Vetuschi A, D'Alfonso A, Sferra R, Zanelli D, Pompili S, Patacchiola F, Gaudio E, Carta G.

Eur J Histochem. 2016 Feb 16;60(1):2604. doi: 10.4081/ejh.2016.2604.

46.

Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas.

Gaudio E, Tarantelli C, Kwee I, Barassi C, Bernasconi E, Rinaldi A, Ponzoni M, Cascione L, Targa A, Stathis A, Goodstal S, Zucca E, Bertoni F.

Ann Oncol. 2016 Jun;27(6):1123-8. doi: 10.1093/annonc/mdw131. Epub 2016 Mar 8.

PMID:
26961147
47.

Stem/Progenitor Cell Niches Involved in Hepatic and Biliary Regeneration.

Carpino G, Renzi A, Franchitto A, Cardinale V, Onori P, Reid L, Alvaro D, Gaudio E.

Stem Cells Int. 2016;2016:3658013. doi: 10.1155/2016/3658013. Epub 2016 Jan 10. Review.

48.

Peribiliary Glands as a Niche of Extrapancreatic Precursors Yielding Insulin-Producing Cells in Experimental and Human Diabetes.

Carpino G, Puca R, Cardinale V, Renzi A, Scafetta G, Nevi L, Rossi M, Berloco PB, Ginanni Corradini S, Reid LM, Maroder M, Gaudio E, Alvaro D.

Stem Cells. 2016 May;34(5):1332-42. doi: 10.1002/stem.2311. Epub 2016 Feb 26.

49.

Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage.

Marampon F, Gravina G, Ju X, Vetuschi A, Sferra R, Casimiro M, Pompili S, Festuccia C, Colapietro A, Gaudio E, Di Cesare E, Tombolini V, Pestell RG.

Oncotarget. 2016 Feb 2;7(5):5383-400. doi: 10.18632/oncotarget.6579. Erratum in: Oncotarget. 2016 Sep 27;7(39):64526.

50.

Progenitor cell niches in the human pancreatic duct system and associated pancreatic duct glands: an anatomical and immunophenotyping study.

Carpino G, Renzi A, Cardinale V, Franchitto A, Onori P, Overi D, Rossi M, Berloco PB, Alvaro D, Reid LM, Gaudio E.

J Anat. 2016 Mar;228(3):474-86. doi: 10.1111/joa.12418. Epub 2015 Nov 27.

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