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Items: 1 to 50 of 308

1.

The Contribution of the Adipose Tissue-Liver Axis in Pediatric Patients with Nonalcoholic Fatty Liver Disease after Laparoscopic Sleeve Gastrectomy.

Franchitto A, Carpino G, Alisi A, De Peppo F, Overi D, De Stefanis C, Romito I, De Vito R, Caccamo R, Sonia B, Alessandra S, Mosca A, Alterio A, Onori P, Gaudio E, Nobili V.

J Pediatr. 2019 Sep 13. pii: S0022-3476(19)30889-3. doi: 10.1016/j.jpeds.2019.07.037. [Epub ahead of print]

PMID:
31526528
2.

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas.

Zaccari P, Cardinale V, Severi C, Pedica F, Carpino G, Gaudio E, Doglioni C, Petrone MC, Alvaro D, Arcidiacono PG, Capurso G.

World J Gastroenterol. 2019 Aug 21;25(31):4343-4359. doi: 10.3748/wjg.v25.i31.4343. Review.

3.

Can Nrf2 Modulate the Development of Intestinal Fibrosis and Cancer in Inflammatory Bowel Disease?

Pompili S, Sferra R, Gaudio E, Viscido A, Frieri G, Vetuschi A, Latella G.

Int J Mol Sci. 2019 Aug 20;20(16). pii: E4061. doi: 10.3390/ijms20164061. Review.

4.

Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines.

Fallacara AL, Passannanti R, Mori M, Iovenitti G, Musumeci F, Greco C, Crespan E, Kissova M, Maga G, Tarantelli C, Spriano F, Gaudio E, Bertoni F, Botta M, Schenone S.

Eur J Med Chem. 2019 Nov 1;181:111545. doi: 10.1016/j.ejmech.2019.07.048. Epub 2019 Jul 18.

PMID:
31400706
5.

Single and combined BTK and PI3Kδ inhibition with acalabrutinib and ACP-319 in pre-clinical models of aggressive lymphomas.

Spriano F, Tarantelli C, Gaudio E, Gerlach MM, Priebe V, Cascione L, Bernasconi E, Targa A, Mascia M, Dirnhofer S, Stathis A, Zucca E, Bertoni F.

Br J Haematol. 2019 Jul 29. doi: 10.1111/bjh.16118. [Epub ahead of print]

PMID:
31355927
6.

Peribiliary Gland Niche Participates in Biliary Tree Regeneration in Mouse and in Human Primary Sclerosing Cholangitis.

Carpino G, Nevi L, Overi D, Cardinale V, Lu WY, Di Matteo S, Safarikia S, Berloco PB, Venere R, Onori P, Franchitto A, Forbes SJ, Alvaro D, Gaudio E.

Hepatology. 2019 Jul 22. doi: 10.1002/hep.30871. [Epub ahead of print]

PMID:
31330051
7.

Secretin/secretin receptor signaling mediates biliary damage and liver fibrosis in early-stage primary biliary cholangitis.

Kennedy L, Francis H, Invernizzi P, Venter J, Wu N, Carbone M, Gershwin ME, Bernuzzi F, Franchitto A, Alvaro D, Marzioni M, Onori P, Gaudio E, Sybenga A, Fabris L, Meng F, Glaser S, Alpini G.

FASEB J. 2019 Sep;33(9):10269-10279. doi: 10.1096/fj.201802606R. Epub 2019 Jun 28.

PMID:
31251081
8.

The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents.

Spriano F, Chung EYL, Gaudio E, Tarantelli C, Cascione L, Napoli S, Jessen K, Carrassa L, Priebe V, Sartori G, Graham G, Selvanathan SP, Cavalli A, Rinaldi A, Kwee I, Testoni M, Genini D, Ye BH, Zucca E, Stathis A, Lannutti B, Toretsky JA, Bertoni F.

Clin Cancer Res. 2019 Aug 15;25(16):5167-5176. doi: 10.1158/1078-0432.CCR-18-2718. Epub 2019 Jun 10.

PMID:
31182435
9.

The Novel TORC1/2 Kinase Inhibitor PQR620 Has Anti-Tumor Activity in Lymphomas as a Single Agent and in Combination with Venetoclax.

Tarantelli C, Gaudio E, Hillmann P, Spriano F, Sartori G, Aresu L, Cascione L, Rageot D, Kwee I, Beaufils F, Zucca E, Stathis A, Wymann MP, Cmiljanovic V, Fabbro D, Bertoni F.

Cancers (Basel). 2019 Jun 4;11(6). pii: E775. doi: 10.3390/cancers11060775.

10.

Neurovascular alterations of muscularis propria in the human anterior vaginal wall in pelvic organ prolapse.

Sferra R, Pompili S, D'Alfonso A, Sabetta G, Gaudio E, Carta G, Festuccia C, Colapietro A, Vetuschi A.

J Anat. 2019 Aug;235(2):281-288. doi: 10.1111/joa.13014. Epub 2019 May 30.

11.

Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor.

Franchitto A, Overi D, Mancinelli R, Mitterhofer AP, Muiesan P, Tinti F, Umbro I, Hubscher SG, Onori P, Gaudio E, Carpino G.

Eur J Histochem. 2019 May 10;63(2). doi: 10.4081/ejh.2019.3022.

12.

Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells.

Ohkubo S, Mancinelli R, Miglietta S, Cona A, Angelini R, Canettieri G, Spandidos DA, Gaudio E, Agostinelli E.

Int J Oncol. 2019 Jun;54(6):2080-2094. doi: 10.3892/ijo.2019.4780. Epub 2019 Apr 10.

13.

DNA Damage Response Inhibitor Combinations Exert Synergistic Antitumor Activity in Aggressive B-Cell Lymphomas.

Restelli V, Lupi M, Chilà R, Vagni M, Tarantelli C, Spriano F, Gaudio E, Bertoni F, Damia G, Carrassa L.

Mol Cancer Ther. 2019 Jul;18(7):1255-1264. doi: 10.1158/1535-7163.MCT-18-0919. Epub 2019 May 7.

PMID:
31064869
14.

The Role of Autophagy in Liver Epithelial Cells and Its Impact on Systemic Homeostasis.

Tomaipitinca L, Mandatori S, Mancinelli R, Giulitti F, Petrungaro S, Moresi V, Facchiano A, Ziparo E, Gaudio E, Giampietri C.

Nutrients. 2019 Apr 11;11(4). pii: E827. doi: 10.3390/nu11040827. Review.

15.

Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells.

Costantini D, Overi D, Casadei L, Cardinale V, Nevi L, Carpino G, Di Matteo S, Safarikia S, Valerio M, Melandro F, Bizzarri M, Manetti C, Berloco PB, Gaudio E, Alvaro D.

Sci Rep. 2019 Apr 3;9(1):5559. doi: 10.1038/s41598-019-41908-5.

16.

Perampanel Pharmacokinetics in Children: Correlation of Dose With Serum Concentrations.

Gaudio E, Gienapp AJ, Wheless J.

J Child Neurol. 2019 Jul;34(8):427-431. doi: 10.1177/0883073819837465. Epub 2019 Mar 25.

PMID:
30909831
17.

Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis.

Chen L, Zhou T, Wu N, O'Brien A, Venter J, Ceci L, Kyritsi K, Onori P, Gaudio E, Sybenga A, Xie L, Wu C, Fabris L, Invernizzi P, Zawieja D, Liangpunsakul S, Meng F, Francis H, Alpini G, Huang Q, Glaser S.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1525-1539. doi: 10.1016/j.bbadis.2019.03.002. Epub 2019 Mar 16.

PMID:
30890428
18.

Anatomical, histomorphological and molecular classification of cholangiocarcinoma.

Kendall T, Verheij J, Gaudio E, Evert M, Guido M, Goeppert B, Carpino G.

Liver Int. 2019 May;39 Suppl 1:7-18. doi: 10.1111/liv.14093. Review.

PMID:
30882996
19.

Nutrition education in medical schools (NEMS). An ESPEN position paper.

Cuerda C, Muscaritoli M, Donini LM, Baqué P, Barazzoni R, Gaudio E, Jezek D, Krznaric Z, Pirlich M, Schetgen M, Schneider S, Vargas JA, Van Gossum A.

Clin Nutr. 2019 Jun;38(3):969-974. doi: 10.1016/j.clnu.2019.02.001. Epub 2019 Feb 7.

PMID:
30772092
20.

Fhit-Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells.

Druck T, Cheung DG, Park D, Trapasso F, Pichiorri F, Gaspari M, Palumbo T, Aqeilan RI, Gaudio E, Okumura H, Iuliano R, Raso C, Green K, Huebner K, Croce CM.

Cell Death Dis. 2019 Feb 15;10(3):147. doi: 10.1038/s41419-019-1414-7.

21.

The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models.

Hicks SW, Tarantelli C, Wilhem A, Gaudio E, Li M, Arribas AJ, Spriano F, Bordone R, Cascione L, Lai KC, Qiu Q, Taborelli M, Rossi D, Stussi G, Zucca E, Stathis A, Sloss CM, Bertoni F.

Haematologica. 2019 Aug;104(8):1633-1639. doi: 10.3324/haematol.2018.211011. Epub 2019 Feb 7.

22.

The Bruton tyrosine kinase inhibitor zanubrutinib (BGB-3111) demonstrated synergies with other anti-lymphoma targeted agents.

Tarantelli C, Zhang L, Curti E, Gaudio E, Spriano F, Priebe V, Cascione L, Arribas AJ, Zucca E, Rossi D, Stathis A, Bertoni F.

Haematologica. 2019 Jul;104(7):e307-e309. doi: 10.3324/haematol.2018.214759. Epub 2019 Jan 24. No abstract available.

23.

The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma.

Di Matteo S, Nevi L, Costantini D, Overi D, Carpino G, Safarikia S, Giulitti F, Napoletano C, Manzi E, De Rose AM, Melandro F, Bragazzi M, Berloco PB, Giuliante F, Grazi G, Giorgi A, Cardinale V, Adorini L, Gaudio E, Alvaro D.

PLoS One. 2019 Jan 24;14(1):e0210077. doi: 10.1371/journal.pone.0210077. eCollection 2019.

24.

PPAR-γ with its anti-inflammatory and anti-fibrotic action could be an effective therapeutic target in IBD.

Vetuschi A, Pompili S, Gaudio E, Latella G, Sferra R.

Eur Rev Med Pharmacol Sci. 2018 Dec;22(24):8839-8848. doi: 10.26355/eurrev_201812_16652.

25.

In vitro demonstration of synergism with pixantrone combined with targeted agents in lymphomas.

Tarantelli C, Gaudio E, Cascione L, Stathis A, Zucca E, Bertoni F.

Br J Haematol. 2019 Jul;186(1):149-152. doi: 10.1111/bjh.15727. Epub 2018 Dec 19. No abstract available.

PMID:
30569468
26.

New molecular and therapeutic insights into canine diffuse large B-cell lymphoma elucidates the role of the dog as a model for human disease.

Aresu L, Ferraresso S, Marconato L, Cascione L, Napoli S, Gaudio E, Kwee I, Tarantelli C, Testa A, Maniaci C, Ciulli A, Hillmann P, Bohnacker T, Wymann MP, Comazzi S, Milan M, Riondato F, Rovere GD, Giantin M, Giannuzzi D, Bertoni F.

Haematologica. 2019 Jun;104(6):e256-e259. doi: 10.3324/haematol.2018.207027. Epub 2018 Dec 13. No abstract available.

27.

Validation of epigenetic mechanisms regulating gene expression in canine B-cell lymphoma: An in vitro and in vivo approach.

Da Ros S, Aresu L, Ferraresso S, Zorzan E, Gaudio E, Bertoni F, Dacasto M, Giantin M.

PLoS One. 2018 Dec 11;13(12):e0208709. doi: 10.1371/journal.pone.0208709. eCollection 2018.

28.

Peribiliary Glands Are Key in Regeneration of the Human Biliary Epithelium After Severe Bile Duct Injury.

de Jong IEM, Matton APM, van Praagh JB, van Haaften WT, Wiersema-Buist J, van Wijk LA, Oosterhuis D, Iswandana R, Suriguga S, Overi D, Lisman T, Carpino G, Gouw ASH, Olinga P, Gaudio E, Porte RJ.

Hepatology. 2019 Apr;69(4):1719-1734. doi: 10.1002/hep.30365. Epub 2019 Mar 5.

29.

BET bromodomain inhibitor birabresib in mantle cell lymphoma: in vivo activity and identification of novel combinations to overcome adaptive resistance.

Tarantelli C, Bernasconi E, Gaudio E, Cascione L, Restelli V, Arribas AJ, Spriano F, Rinaldi A, Mensah AA, Kwee I, Ponzoni M M.D, Zucca E, Carrassa L, Riveiro ME, Rezai K, Stathis A, Cvitkovic E, Bertoni F.

ESMO Open. 2018 Sep 26;3(6):e000387. doi: 10.1136/esmoopen-2018-000387. eCollection 2018.

30.

Contribution of Resident Stem Cells to Liver and Biliary Tree Regeneration in Human Diseases.

Overi D, Carpino G, Cardinale V, Franchitto A, Safarikia S, Onori P, Alvaro D, Gaudio E.

Int J Mol Sci. 2018 Sep 25;19(10). pii: E2917. doi: 10.3390/ijms19102917. Review.

31.

T-Cell Leukemia/Lymphoma 1 (TCL1): An Oncogene Regulating Multiple Signaling Pathways.

Paduano F, Gaudio E, Mensah AA, Pinton S, Bertoni F, Trapasso F.

Front Oncol. 2018 Aug 13;8:317. doi: 10.3389/fonc.2018.00317. eCollection 2018.

32.

Leukocyte coping capacity chemiluminescence as an innovative tool for stress and pain assessment in calves undergoing ring castration.

Gaudio E, Bordin S, Lora I, Lora M, Massignani M, De Benedictis GM.

J Anim Sci. 2018 Nov 21;96(11):4579-4589. doi: 10.1093/jas/sky342.

PMID:
30137392
33.

Neoplastic Transformation of the Peribiliary Stem Cell Niche in Cholangiocarcinoma Arisen in Primary Sclerosing Cholangitis.

Carpino G, Cardinale V, Folseraas T, Overi D, Grzyb K, Costantini D, Berloco PB, Di Matteo S, Karlsen TH, Alvaro D, Gaudio E.

Hepatology. 2019 Feb;69(2):622-638. doi: 10.1002/hep.30210. Epub 2019 Jan 4.

PMID:
30102768
34.

Bromodomain and extra-terminal domain inhibition modulates the expression of pathologically relevant microRNAs in diffuse large B-cell lymphoma.

Mensah AA, Cascione L, Gaudio E, Tarantelli C, Bomben R, Bernasconi E, Zito D, Lampis A, Hahne JC, Rinaldi A, Stathis A, Zucca E, Kwee I, Gattei V, Valeri N, Riveiro ME, Bertoni F.

Haematologica. 2018 Dec;103(12):2049-2058. doi: 10.3324/haematol.2018.191684. Epub 2018 Aug 3.

35.

Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study.

Sferra R, Pompili S, Ventura L, Dubuquoy C, Speca S, Gaudio E, Latella G, Vetuschi A.

Eur J Histochem. 2018 Jul 31;62(3). doi: 10.4081/ejh.2018.2956.

36.

The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor-β1-Mediated Biliary Senescence.

Wu N, Meng F, Zhou T, Venter J, Giang TK, Kyritsi K, Wu C, Alvaro D, Onori P, Mancinelli R, Gaudio E, Francis H, Alpini G, Glaser S, Franchitto A.

Am J Pathol. 2018 Oct;188(10):2264-2280. doi: 10.1016/j.ajpath.2018.06.015. Epub 2018 Jul 21.

37.

Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score.

Carbone M, Nardi A, Flack S, Carpino G, Varvaropoulou N, Gavrila C, Spicer A, Badrock J, Bernuzzi F, Cardinale V, Ainsworth HF, Heneghan MA, Thorburn D, Bathgate A, Jones R, Neuberger JM, Battezzati PM, Zuin M, Taylor-Robinson S, Donato MF, Kirby J, Mitchell-Thain R, Floreani A, Sampaziotis F, Muratori L, Alvaro D, Marzioni M, Miele L, Marra F, Giannini E, Gaudio E, Ronca V, Bonato G, Cristoferi L, Malinverno F, Gerussi A, Stocken DD, Cordell HJ, Hirschfield GM, Alexander GJ, Sandford RN, Jones DE, Invernizzi P, Mells GF; Italian PBC Study Group and the UK–PBC Consortium.

Lancet Gastroenterol Hepatol. 2018 Sep;3(9):626-634. doi: 10.1016/S2468-1253(18)30163-8. Epub 2018 Jul 13.

38.

Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes.

Zhou T, Wu N, Meng F, Venter J, Giang TK, Francis H, Kyritsi K, Wu C, Franchitto A, Alvaro D, Marzioni M, Onori P, Mancinelli R, Gaudio E, Glaser S, Alpini G.

Lab Invest. 2018 Nov;98(11):1449-1464. doi: 10.1038/s41374-018-0093-9. Epub 2018 Jul 5.

39.

The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells.

D'Agostino S, Lanzillotta D, Varano M, Botta C, Baldrini A, Bilotta A, Scalise S, Dattilo V, Amato R, Gaudio E, Paduano F, Palmieri C, Iuliano R, Perrotti N, Indiveri C, Fusco A, Gaspari M, Trapasso F.

Oncotarget. 2018 May 4;9(34):23334-23348. doi: 10.18632/oncotarget.25101. eCollection 2018 May 4.

40.

Immunolocalization of Advanced Glycation End Products, Mitogen Activated Protein Kinases, and Transforming Growth Factor-β/Smads in Pelvic Organ Prolapse.

Vetuschi A, Pompili S, Gallone A, D'Alfonso A, Carbone MG, Carta G, Festuccia C, Gaudio E, Colapietro A, Sferra R.

J Histochem Cytochem. 2018 Sep;66(9):673-686. doi: 10.1369/0022155418772798. Epub 2018 May 8.

41.

Liquid Biopsy in Rare Cancers: Lessons from Hemangiopericytoma.

Nicolazzo C, Colangelo L, Corsi A, Carpino G, Gradilone A, Sonato C, Raimondi C, Gaudio E, Gazzaniga P, Gianni W.

Anal Cell Pathol (Amst). 2018 Mar 7;2018:9718585. doi: 10.1155/2018/9718585. eCollection 2018.

42.

Alfaxalone anaesthesia in Lemur catta following dexmedetomidine-butorphanol-midazolam sedation.

Gaudio E, Voltan L, De Benedictis GM.

Vet Anaesth Analg. 2018 May;45(3):351-356. doi: 10.1016/j.vaa.2018.01.004. Epub 2018 Feb 3.

PMID:
29625917
43.

Role of lactoferrin and its receptors on biliary epithelium.

Mancinelli R, Olivero F, Carpino G, Overi D, Rosa L, Lepanto MS, Cutone A, Franchitto A, Alpini G, Onori P, Valenti P, Gaudio E.

Biometals. 2018 Jun;31(3):369-379. doi: 10.1007/s10534-018-0094-6. Epub 2018 Mar 17.

PMID:
29550924
44.

Overexpression of the Vitronectin V10 Subunit in Patients with Nonalcoholic Steatohepatitis: Implications for Noninvasive Diagnosis of NASH.

Del Ben M, Overi D, Polimeni L, Carpino G, Labbadia G, Baratta F, Pastori D, Noce V, Gaudio E, Angelico F, Mancone C.

Int J Mol Sci. 2018 Feb 18;19(2). pii: E603. doi: 10.3390/ijms19020603.

45.

Hepatic Stem/Progenitor Cell Activation Differs between Primary Sclerosing and Primary Biliary Cholangitis.

Carpino G, Cardinale V, Folseraas T, Overi D, Floreani A, Franchitto A, Onori P, Cazzagon N, Berloco PB, Karlsen TH, Alvaro D, Gaudio E.

Am J Pathol. 2018 Mar;188(3):627-639. doi: 10.1016/j.ajpath.2017.11.010. Epub 2017 Dec 15.

PMID:
29248458
46.

PD-L1 and epithelial-mesenchymal transition in circulating tumor cells from non-small cell lung cancer patients: A molecular shield to evade immune system?

Raimondi C, Carpino G, Nicolazzo C, Gradilone A, Gianni W, Gelibter A, Gaudio E, Cortesi E, Gazzaniga P.

Oncoimmunology. 2017 Apr 20;6(12):e1315488. doi: 10.1080/2162402X.2017.1315488. eCollection 2017.

47.

Laparoscopic Sleeve Gastrectomy Improves Nonalcoholic Fatty Liver Disease-Related Liver Damage in Adolescents by Reshaping Cellular Interactions and Hepatic Adipocytokine Production.

Nobili V, Carpino G, De Peppo F, Caccamo R, Mosca A, Romito I, Overi D, Franchitto A, Onori P, Alisi A, Gaudio E.

J Pediatr. 2018 Mar;194:100-108.e3. doi: 10.1016/j.jpeds.2017.10.036. Epub 2017 Dec 1.

PMID:
29198531
48.

PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress.

Carpino G, Pastori D, Baratta F, Overi D, Labbadia G, Polimeni L, Di Costanzo A, Pannitteri G, Carnevale R, Del Ben M, Arca M, Violi F, Angelico F, Gaudio E.

Sci Rep. 2017 Nov 17;7(1):15756. doi: 10.1038/s41598-017-15943-z.

49.

Endodontic treatment of canine teeth in a cynomolgus monkey ( Macaca fascicularis).

Facchini C, Iacopetti I, Gaudio E, Zotti A, Boldrin M, Fante F, Mutinelli F, Cozzi E, De Benedictis GM.

Lab Anim. 2018 Jun;52(3):308-312. doi: 10.1177/0023677217737568. Epub 2017 Nov 10.

PMID:
29126360
50.

Activation of Fas/FasL pathway and the role of c-FLIP in primary culture of human cholangiocarcinoma cells.

Carnevale G, Carpino G, Cardinale V, Pisciotta A, Riccio M, Bertoni L, Gibellini L, De Biasi S, Nevi L, Costantini D, Overi D, Cossarizza A, de Pol A, Gaudio E, Alvaro D.

Sci Rep. 2017 Oct 31;7(1):14419. doi: 10.1038/s41598-017-14838-3.

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