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Items: 25


House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation.

Serhan N, Basso L, Sibilano R, Petitfils C, Meixiong J, Bonnart C, Reber LL, Marichal T, Starkl P, Cenac N, Dong X, Tsai M, Galli SJ, Gaudenzio N.

Nat Immunol. 2019 Oct 7. doi: 10.1038/s41590-019-0493-z. [Epub ahead of print]


Peripheral neurons: Master regulators of skin and mucosal immune response.

Basso L, Serhan N, Tauber M, Gaudenzio N.

Eur J Immunol. 2019 Jul 21. doi: 10.1002/eji.201848027. [Epub ahead of print] Review.


A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity.

Pundir P, Liu R, Vasavda C, Serhan N, Limjunyawong N, Yee R, Zhan Y, Dong X, Wu X, Zhang Y, Snyder SH, Gaudenzio N, Vidal JE, Dong X.

Cell Host Microbe. 2019 Jul 10;26(1):114-122.e8. doi: 10.1016/j.chom.2019.06.003. Epub 2019 Jul 2.


Genetic and Imaging Approaches Reveal Pro-Inflammatory and Immunoregulatory Roles of Mast Cells in Contact Hypersensitivity.

Gaudenzio N, Marichal T, Galli SJ, Reber LL.

Front Immunol. 2018 Jun 5;9:1275. doi: 10.3389/fimmu.2018.01275. eCollection 2018. Review.


The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice.

Reber LL, Starkl P, Balbino B, Sibilano R, Gaudenzio N, Rogalla S, Sensarn S, Kang D, Raghu H, Sokolove J, Robinson WH, Contag CH, Tsai M, Galli SJ.

PLoS One. 2017 Oct 5;12(10):e0185704. doi: 10.1371/journal.pone.0185704. eCollection 2017.


Human mast cells as antigen-presenting cells: When is this role important in vivo?

Galli SJ, Gaudenzio N.

J Allergy Clin Immunol. 2018 Jan;141(1):92-93. doi: 10.1016/j.jaci.2017.05.029. Epub 2017 Jun 15. No abstract available.


A new fluorescent-avidin-based method for quantifying basophil activation in whole blood.

Mukai K, Chinthrajah RS, Nadeau KC, Tsai M, Gaudenzio N, Galli SJ.

J Allergy Clin Immunol. 2017 Oct;140(4):1202-1206.e3. doi: 10.1016/j.jaci.2017.03.052. Epub 2017 Jun 9. No abstract available.


Imaging protective mast cells in living mice during severe contact hypersensitivity.

Reber LL, Sibilano R, Starkl P, Roers A, Grimbaldeston MA, Tsai M, Gaudenzio N, Galli SJ.

JCI Insight. 2017 May 4;2(9). pii: 92900. doi: 10.1172/jci.insight.92900. eCollection 2017 May 4.


Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide.

Reber LL, Gillis CM, Starkl P, Jönsson F, Sibilano R, Marichal T, Gaudenzio N, Bérard M, Rogalla S, Contag CH, Bruhns P, Galli SJ.

J Exp Med. 2017 May 1;214(5):1249-1258. doi: 10.1084/jem.20161238. Epub 2017 Apr 6.


Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.

Ho CCM, Chhabra A, Starkl P, Schnorr PJ, Wilmes S, Moraga I, Kwon HS, Gaudenzio N, Sibilano R, Wehrman TS, Gakovic M, Sockolosky JT, Tiffany MR, Ring AM, Piehler J, Weissman IL, Galli SJ, Shizuru JA, Garcia KC.

Cell. 2017 Mar 9;168(6):1041-1052.e18. doi: 10.1016/j.cell.2017.02.011.


A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice.

Sibilano R, Gaudenzio N, DeGorter MK, Reber LL, Hernandez JD, Starkl PM, Zurek OW, Tsai M, Zahner S, Montgomery SB, Roers A, Kronenberg M, Yu M, Galli SJ.

Nat Commun. 2016 Dec 16;7:13696. doi: 10.1038/ncomms13696.


Neutrophils are not required for resolution of acute gouty arthritis in mice.

Reber LL, Gaudenzio N, Starkl P, Galli SJ.

Nat Med. 2016 Dec 6;22(12):1382-1384. doi: 10.1038/nm.4216. No abstract available.


Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.

Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, Reber LL, Pirottin D, Kim J, Chambon P, Roers A, Antoine N, Kawakami Y, Kawakami T, Bureau F, Tam SY, Tsai M, Galli SJ.

J Clin Invest. 2016 Dec 1;126(12):4497-4515. doi: 10.1172/JCI86359. Epub 2016 Nov 7.


Different activation signals induce distinct mast cell degranulation strategies.

Gaudenzio N, Sibilano R, Marichal T, Starkl P, Reber LL, Cenac N, McNeil BD, Dong X, Hernandez JD, Sagi-Eisenberg R, Hammel I, Roers A, Valitutti S, Tsai M, Espinosa E, Galli SJ.

J Clin Invest. 2016 Oct 3;126(10):3981-3998. doi: 10.1172/JCI85538. Epub 2016 Sep 19.


Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis.

Balbino B, Sibilano R, Starkl P, Marichal T, Gaudenzio N, Karasuyama H, Bruhns P, Tsai M, Reber LL, Galli SJ.

J Allergy Clin Immunol. 2017 Feb;139(2):584-596.e10. doi: 10.1016/j.jaci.2016.05.047. Epub 2016 Jul 17.


Assessing basophil activation by using flow cytometry and mass cytometry in blood stored 24 hours before analysis.

Mukai K, Gaudenzio N, Gupta S, Vivanco N, Bendall SC, Maecker HT, Chinthrajah RS, Tsai M, Nadeau KC, Galli SJ.

J Allergy Clin Immunol. 2017 Mar;139(3):889-899.e11. doi: 10.1016/j.jaci.2016.04.060. Epub 2016 Jul 15.


Melanoma cell lysosome secretory burst neutralizes the CTL-mediated cytotoxicity at the lytic synapse.

Khazen R, Müller S, Gaudenzio N, Espinosa E, Puissegur MP, Valitutti S.

Nat Commun. 2016 Mar 4;7:10823. doi: 10.1038/ncomms10823.


IgE antibodies, FcεRIα, and IgE-mediated local anaphylaxis can limit snake venom toxicity.

Starkl P, Marichal T, Gaudenzio N, Reber LL, Sibilano R, Tsai M, Galli SJ.

J Allergy Clin Immunol. 2016 Jan;137(1):246-257.e11. doi: 10.1016/j.jaci.2015.08.005. Epub 2015 Sep 26.


MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison with LPS.

Schülke S, Flaczyk A, Vogel L, Gaudenzio N, Angers I, Löschner B, Wolfheimer S, Spreitzer I, Qureshi S, Tsai M, Galli S, Vieths S, Scheurer S.

Allergy. 2015 Oct;70(10):1259-68. doi: 10.1111/all.12675. Epub 2015 Jul 8.


Analyzing the Functions of Mast Cells In Vivo Using 'Mast Cell Knock-in' Mice.

Gaudenzio N, Sibilano R, Starkl P, Tsai M, Galli SJ, Reber LL.

J Vis Exp. 2015 May 27;(99):e52753. doi: 10.3791/52753.


Mast cells form antibody-dependent degranulatory synapse for dedicated secretion and defence.

Joulia R, Gaudenzio N, Rodrigues M, Lopez J, Blanchard N, Valitutti S, Espinosa E.

Nat Commun. 2015 Jan 28;6:6174. doi: 10.1038/ncomms7174.


Contribution of mast cell-derived interleukin-1β to uric acid crystal-induced acute arthritis in mice.

Reber LL, Marichal T, Sokolove J, Starkl P, Gaudenzio N, Iwakura Y, Karasuyama H, Schwartz LB, Robinson WH, Tsai M, Galli SJ.

Arthritis Rheumatol. 2014 Oct;66(10):2881-91. doi: 10.1002/art.38747.


Reply: To PMID 23518141.

Gaudenzio N, Laurent C, Valitutti S, Espinosa E.

J Allergy Clin Immunol. 2013 Dec;132(6):1458-9. doi: 10.1016/j.jaci.2013.09.025. Epub 2013 Nov 1. No abstract available.


Human mast cells drive memory CD4+ T cells toward an inflammatory IL-22+ phenotype.

Gaudenzio N, Laurent C, Valitutti S, Espinosa E.

J Allergy Clin Immunol. 2013 May;131(5):1400-7.e11. doi: 10.1016/j.jaci.2013.01.029. Epub 2013 Mar 19.


Cell-cell cooperation at the T helper cell/mast cell immunological synapse.

Gaudenzio N, Espagnolle N, Mars LT, Liblau R, Valitutti S, Espinosa E.

Blood. 2009 Dec 3;114(24):4979-88. doi: 10.1182/blood-2009-02-202648. Epub 2009 Oct 5.


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