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The KRASG12C Inhibitor, MRTX849, Provides Insight Toward Therapeutic Susceptibility of KRAS Mutant Cancers in Mouse Models and Patients.

Hallin J, Engstrom LD, Hargis L, Calinisan A, Aranda R, Briere DM, Sudhakar N, Bowcut V, Baer BR, Ballard JA, Burkard MR, Fell JB, Fischer JP, Vigers GP, Xue JY, Gatto S, Fernandez-Banet J, Pavlicek A, Velastegui K, Chao RC, Barton J, Pierobon M, Baldelli E, Patricoin EF, Cassidy DP, Marx MA, Rybkin II, Johnson ML, Ou SI, Lito P, Papadopoulos KP, Janne PA, Olson P, Christensen JG.

Cancer Discov. 2019 Oct 28. pii: CD-19-1167. doi: 10.1158/2159-8290.CD-19-1167. [Epub ahead of print]


Effects of truck transportation and slaughtering on the occurrence of prednisolone and its metabolites in cow urine, liver, and adrenal glands.

Capra P, Leporati M, Nebbia C, Gatto S, Attucci A, Barbarino G, Vincenti M.

BMC Vet Res. 2019 Sep 18;15(1):336. doi: 10.1186/s12917-019-2069-4.


Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation.

Dall'Agnese A, Caputo L, Nicoletti C, di Iulio J, Schmitt A, Gatto S, Diao Y, Ye Z, Forcato M, Perera R, Bicciato S, Telenti A, Ren B, Puri PL.

Mol Cell. 2019 Nov 7;76(3):453-472.e8. doi: 10.1016/j.molcel.2019.07.036. Epub 2019 Sep 10.


Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease.

Lee EC, Valencia T, Allerson C, Schairer A, Flaten A, Yheskel M, Kersjes K, Li J, Gatto S, Takhar M, Lockton S, Pavlicek A, Kim M, Chu T, Soriano R, Davis S, Androsavich JR, Sarwary S, Owen T, Kaplan J, Liu K, Jang G, Neben S, Bentley P, Wright T, Patel V.

Nat Commun. 2019 Sep 12;10(1):4148. doi: 10.1038/s41467-019-11918-y.


Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD.

Coenen-Stass AML, Sork H, Gatto S, Godfrey C, Bhomra A, Krjutškov K, Hart JR, Westholm JO, O'Donovan L, Roos A, Lochmüller H, Puri PL, El Andaloussi S, Wood MJA, Roberts TC.

Mol Ther Nucleic Acids. 2018 Dec 7;13:1-15. doi: 10.1016/j.omtn.2018.08.005. Epub 2018 Aug 17.


Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy.

Malecova B, Gatto S, Etxaniz U, Passafaro M, Cortez A, Nicoletti C, Giordani L, Torcinaro A, De Bardi M, Bicciato S, De Santa F, Madaro L, Puri PL.

Nat Commun. 2018 Sep 10;9(1):3670. doi: 10.1038/s41467-018-06068-6.


Denervation-activated STAT3-IL-6 signalling in fibro-adipogenic progenitors promotes myofibres atrophy and fibrosis.

Madaro L, Passafaro M, Sala D, Etxaniz U, Lugarini F, Proietti D, Alfonsi MV, Nicoletti C, Gatto S, De Bardi M, Rojas-García R, Giordani L, Marinelli S, Pagliarini V, Sette C, Sacco A, Puri PL.

Nat Cell Biol. 2018 Aug;20(8):917-927. doi: 10.1038/s41556-018-0151-y. Epub 2018 Jul 26.


Effects of Faculty Development and Computerized Learning and Assessment Tools on Testing Outcomes.

Gatto SL, Madden S.

Nurse Educ. 2019 Jan/Feb;44(1):12-14. doi: 10.1097/NNE.0000000000000541. No abstract available.


Curricular Interventions to Promote Self-care in Prelicensure Nursing Students.

Ashcraft PF, Gatto SL.

Nurse Educ. 2018 May/Jun;43(3):140-144. doi: 10.1097/NNE.0000000000000450.


Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.

Cui H, Bansal V, Grunert M, Malecova B, Dall'Agnese A, Latella L, Gatto S, Ryan T, Schulz K, Chen W, Dorn C, Puri PL, Sperling SR.

PLoS One. 2017 Jun 13;12(6):e0179464. doi: 10.1371/journal.pone.0179464. eCollection 2017.


ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing.

Gatto S, Gagliardi M, Franzese M, Leppert S, Papa M, Cammisa M, Grillo G, Velasco G, Francastel C, Toubiana S, D'Esposito M, Angelini C, Matarazzo MR.

Nucleic Acids Res. 2017 Jun 2;45(10):5739-5756. doi: 10.1093/nar/gkx163.


Mechanistic understanding of the cysteine capping modifications of antibodies enables selective chemical engineering in live mammalian cells.

Zhong X, He T, Prashad AS, Wang W, Cohen J, Ferguson D, Tam AS, Sousa E, Lin L, Tchistiakova L, Gatto S, D'Antona A, Luan YT, Ma W, Zollner R, Zhou J, Arve B, Somers W, Kriz R.

J Biotechnol. 2017 Apr 20;248:48-58. doi: 10.1016/j.jbiotec.2017.03.006. Epub 2017 Mar 11.


Single Cell Gene Expression Profiling of Skeletal Muscle-Derived Cells.

Gatto S, Puri PL, Malecova B.

Methods Mol Biol. 2017;1556:191-219. doi: 10.1007/978-1-4939-6771-1_10.


Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer.

Root AR, Cao W, Li B, LaPan P, Meade C, Sanford J, Jin M, O'Sullivan C, Cummins E, Lambert M, Sheehan AD, Ma W, Gatto S, Kerns K, Lam K, D'Antona AM, Zhu L, Brady WA, Benard S, King A, He T, Racie L, Arai M, Barrett D, Stochaj W, LaVallie ER, Apgar JR, Svenson K, Mosyak L, Yang Y, Chichili GR, Liu L, Li H, Burke S, Johnson S, Alderson R, Finlay WJJ, Lin L, Olland S, Somers W, Bonvini E, Gerber HP, May C, Moore PA, Tchistiakova L, Bloom L.

Antibodies (Basel). 2016 Mar 4;5(1). pii: E6. doi: 10.3390/antib5010006.


TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells.

Malecova B, Dall'Agnese A, Madaro L, Gatto S, Coutinho Toto P, Albini S, Ryan T, Tora L, Puri PL.

Elife. 2016 Feb 25;5. pii: e12534. doi: 10.7554/eLife.12534.


How the knowledge of fracture risk might influence adherence to oral therapy of osteoporosis in Italy: the ADEOST study.

Gonnelli S, Caffarelli C, Rossi S, Di Munno O, Malavolta N, Isaia G, Muratore M, D'Avola G, Gatto S, Minisola G, Nuti R.

Aging Clin Exp Res. 2016 Jun;28(3):459-68. doi: 10.1007/s40520-016-0538-1. Epub 2016 Feb 12.


The Complex Dance of the Two Conformers of Bis(trifluoromethanesulfonyl)imide as a Function of Pressure and Temperature.

Capitani F, Gatto S, Postorino P, Palumbo O, Trequattrini F, Deutsch M, Brubach JB, Roy P, Paolone A.

J Phys Chem B. 2016 Feb 25;120(7):1312-8. doi: 10.1021/acs.jpcb.5b12537. Epub 2016 Feb 11.


Prenatal diagnosis of proximal focal femoral deficiency: Literature review of prenatal sonographic findings.

D'Ambrosio V, Pasquali G, Squarcella A, Marcoccia E, De Filippis A, Gatto S, Camilla A, Pizzuti A, La Torre R, Giancotti A.

J Clin Ultrasound. 2016 May;44(4):252-9. doi: 10.1002/jcu.22306. Epub 2015 Sep 26. Review.


Care-of-Self in Undergraduate Nursing Students: A Pilot Study.

Ashcraft PF, Gatto SL.

Nurs Educ Perspect. 2015 Jul-Aug;36(4):255-6.


Genome-Wide DNA Methylation Analysis Identifies Novel Hypomethylated Non-Pericentromeric Genes with Potential Clinical Implications in ICF Syndrome.

Simo-Riudalbas L, Diaz-Lagares A, Gatto S, Gagliardi M, Crujeiras AB, Matarazzo MR, Esteller M, Sandoval J.

PLoS One. 2015 Jul 10;10(7):e0132517. doi: 10.1371/journal.pone.0132517. eCollection 2015.


Optimization of experimental conditions for functional in vitro characterization of humanized antibodies specific for staphylococcal enterotoxin B.

MacIntyre JL, Varshney AK, Wang X, Gatto S, Friedman C, Liu Y, Kerns K, Kovalenko O, Adkins K, Zollner R, Fries BC, Byrne FR.

Int Immunopharmacol. 2015 Sep;28(1):354-8. doi: 10.1016/j.intimp.2015.06.025. Epub 2015 Jun 27.


Profile of the urinary excretion of prednisolone and its metabolites in finishing bulls and cows treated with a therapeutic schedule.

Nebbia C, Capra P, Leporati M, Girolami F, Barbarino G, Gatto S, Vincenti M.

BMC Vet Res. 2014 Sep 30;10:237. doi: 10.1186/s12917-014-0237-0.


STAT3 signaling controls satellite cell expansion and skeletal muscle repair.

Tierney MT, Aydogdu T, Sala D, Malecova B, Gatto S, Puri PL, Latella L, Sacco A.

Nat Med. 2014 Oct;20(10):1182-6. doi: 10.1038/nm.3656. Epub 2014 Sep 7.


Augmentation or reconstruction of PCL? A quantitative review.

Del Buono A, Radmilovic J, Gargano G, Gatto S, Maffulli N.

Knee Surg Sports Traumatol Arthrosc. 2013 May;21(5):1050-63. doi: 10.1007/s00167-013-2418-y. Epub 2013 Feb 2. Review.


A field survey on the presence of prednisolone and prednisone in urine samples from untreated cows.

Vincenti M, Leporati M, Capra P, Gatto S, Attucci A, Barbarino G, Nebbia C.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012;29(12):1893-900. doi: 10.1080/19440049.2012.719645. Epub 2012 Sep 11.


Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient.

Heyn H, Vidal E, Sayols S, Sanchez-Mut JV, Moran S, Medina I, Sandoval J, Simó-Riudalbas L, Szczesna K, Huertas D, Gatto S, Matarazzo MR, Dopazo J, Esteller M.

Epigenetics. 2012 Jun 1;7(6):542-50. doi: 10.4161/epi.20523. Epub 2012 Jun 1.


Prevention of falls and role of calcium and vitamin D.

Gatto S, Gimigliano F, Gimigliano R, Iolascon G.

Aging Clin Exp Res. 2011 Apr;23(2 Suppl):20-1. Review.


Variegated silencing through epigenetic modifications of a large Xq region in a case of balanced X;2 translocation with Incontinentia Pigmenti-like phenotype.

Genesio R, Melis D, Gatto S, Izzo A, Ronga V, Cappuccio G, Lanzo A, Andria G, D'Esposito M, Matarazzo MR, Conti A, Nitsch L.

Epigenetics. 2011 Oct 1;6(10):1242-7. doi: 10.4161/epi.6.10.17698. Epub 2011 Oct 1.


Uptake and outcomes of a prevention-of mother-to-child transmission (PMTCT) program in Zomba district, Malawi.

van Lettow M, Bedell R, Landes M, Gawa L, Gatto S, Mayuni I, Chan AK, Tenthani L, Schouten E.

BMC Public Health. 2011 Jun 3;11:426. doi: 10.1186/1471-2458-11-426.


Hematologic improvement and response in elderly AML/RAEB patients treated with valproic acid and low-dose Ara-C.

Corsetti MT, Salvi F, Perticone S, Baraldi A, De Paoli L, Gatto S, Pietrasanta D, Pini M, Primon V, Zallio F, Tonso A, Alvaro MG, Ciravegna G, Levis A.

Leuk Res. 2011 Aug;35(8):991-7. doi: 10.1016/j.leukres.2011.02.021. Epub 2011 Apr 6.


Epigenetic alteration of microRNAs in DNMT3B-mutated patients of ICF syndrome.

Gatto S, Della Ragione F, Cimmino A, Strazzullo M, Fabbri M, Mutarelli M, Ferraro L, Weisz A, D'Esposito M, Matarazzo MR.

Epigenetics. 2010 Jul 1;5(5):427-43. Epub 2010 Jul 1.


Fondaparinux in major orthopedic surgical patients.

Santi R, Contino L, Gatto S, Levis A.

Intern Emerg Med. 2010 Apr;5(2):167. doi: 10.1007/s11739-010-0364-y. Epub 2010 Mar 2. No abstract available.


Periprosthetic bone density as outcome of therapeutic response.

Iolascon G, Di Pietro G, Capaldo A, Gioia C, Gatto S, Gimigliano F.

Clin Cases Miner Bone Metab. 2010 Jan;7(1):27-31.


One-year follow-up of epithelial corneal cell sheet allografts mounted on platelet poor plasma in rabbits.

Luengo Gimeno F, Lavigne V, Gatto S, Croxatto JO, Correa L, Gallo JE.

Mol Vis. 2009 Dec 15;15:2771-9.


Hip fractures in Italy: 2000-2005 extension study.

Piscitelli P, Gimigliano F, Gatto S, Marinelli A, Gimigliano A, Marinelli P, Chitano G, Greco M, Di Paola L, Sbenaglia E, Benvenuto M, Muratore M, Quarta E, Calcagnile F, Colì G, Borgia O, Forcina B, Fitto F, Giordano A, Distante A, Rossini M, Angeli A, Migliore A, Guglielmi G, Guida G, Brandi ML, Gimigliano R, Iolascon G.

Osteoporos Int. 2010 Aug;21(8):1323-30. doi: 10.1007/s00198-009-1084-x. Epub 2009 Oct 7.


In vivo lamellar keratoplasty using platelet-rich plasma as a bioadhesive.

Luengo Gimeno F, Gatto SC, Croxatto JO, Ferro JI, Gallo JE.

Eye (Lond). 2010 Feb;24(2):368-75. doi: 10.1038/eye.2009.49. Epub 2009 Mar 20.


Attachment and God representations among lay Catholics, priests, and religious: a matched comparison study based on the Adult Attachment Interview.

Cassibba R, Granqvist P, Costantini A, Gatto S.

Dev Psychol. 2008 Nov;44(6):1753-1763. doi: 10.1037/a0013772.


[Methodology assessment of the first-aid in a company].

Pizzino P, Guarascio D, Gatto S, Nigro C.

G Ital Med Lav Ergon. 2007 Jul-Sep;29(3 Suppl):771-2. Italian.


Cardiovascular disease and osteoporosis: balancing risk management.

Warburton DE, Nicol CW, Gatto SN, Bredin SS.

Vasc Health Risk Manag. 2007;3(5):673-89. Review.


Advances in corneal stem-cell transplantation in rabbits with severe ocular alkali burns.

Luengo Gimeno F, Lavigne V, Gatto S, Croxatto JO, Correa L, Gallo JE.

J Cataract Refract Surg. 2007 Nov;33(11):1958-65.


[Chronic lumbago after unstable intertrochanteric femoral fracture: a new syndrome or sporadic feature of hip biomechanics after surgery? A case report].

Di Lorenzo L, Forte A, Landolfi A, Di Mario M, Formisano R, Gatto S.

G Ital Med Lav Ergon. 2007 Apr-Jun;29(2):210-3. Italian.


Low back pain after unstable extracapsular hip fractures: randomized control trial on a specific training.

Di Lorenzo L, Forte A, Formisano R, Gimigliano R, Gatto S.

Eura Medicophys. 2007 Sep;43(3):349-57. Epub 2007 May 28.


Incidence and costs of hip fractures compared to acute myocardial infarction in the Italian population: a 4-year survey.

Piscitelli P, Iolascon G, Gimigliano F, Muratore M, Camboa P, Borgia O, Forcina B, Fitto F, Robaud V, Termini G, Rini GB, Gianicolo E, Faino A, Rossini M, Adami S, Angeli A, Distante A, Gatto S, Gimigliano R, Guida G; SIOMMMS study group; CERSUM research group.

Osteoporos Int. 2007 Feb;18(2):211-9. Epub 2006 Oct 24.


Preparation of platelet-rich plasma as a tissue adhesive for experimental transplantation in rabbits.

Luengo Gimeno F, Gatto S, Ferro J, Croxatto JO, Gallo JE.

Thromb J. 2006 Sep 28;4:18.


An optic micro-switch for an eyelid response to foster environmental control in children with minimal motor behaviour.

Lancioni GE, Singh NN, O'Reilly MF, Sigafoos J, Oliva D, Costantini A, Gatto S, Marinelli V, Putzolu A.

Pediatr Rehabil. 2006 Jan-Mar;9(1):53-6.


Contribution of the copper ions in the dinuclear active site to the stability of Carcinus aestuarii hemocyanin.

Spinozzi F, Gatto S, De Filippis V, Carsughi F, Di Muro P, Beltramini M.

Arch Biochem Biophys. 2005 Jul 1;439(1):42-52.


Role of liposomal daunorubicin, fludarabine and cytarabine (FLAD) in the salvage therapy of adult acute lymphoblastic leukemia.

Clavio M, Pierri I, Venturino C, Garrone A, Canepa L, Miglino M, Varaldo R, Ballerini F, Michelis GL, Balocco M, Abdall N, Gatto S, Gobbi M.

Leuk Lymphoma. 2004 Dec;45(12):2527-30. No abstract available.


Changes associated with the development of resistance to imatinib (STI571) in two leukemia cell lines expressing p210 Bcr/Abl protein.

Scappini B, Gatto S, Onida F, Ricci C, Divoky V, Wierda WG, Andreeff M, Dong L, Hayes K, Verstovsek S, Kantarjian HM, Beran M.

Cancer. 2004 Apr 1;100(7):1459-71.


Structural role of the copper ions in the dinuclear active site of Carcinus aestuarii hemocyanin.

Gatto S, De Filippis V, Spinozzi F, Di Muro P, Bubacco L, Beltramini M.

Micron. 2004;35(1-2):43-4.


The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in Bcr/Abl-positive cell lines sensitive and resistant to imatinib mesylate.

Gatto S, Scappini B, Pham L, Onida F, Milella M, Ball G, Ricci C, Divoky V, Verstovsek S, Kantarjian HM, Keating MJ, Cortes-Franco JE, Beran M.

Haematologica. 2003 Aug;88(8):853-63.

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