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Items: 41

1.

Erratum: "Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity".

French JE, Gatti DM, Morgan DL, Kissling GE, Shockley KR, Knudsen GA, Shepard KG, Price HC, King D, Witt KL, Pedersen LC, Munger SC, Svenson KL, Churchill GA.

Environ Health Perspect. 2018 Jun 27;126(6):069003. doi: 10.1289/EHP3950. eCollection 2018 Jun.

2.

Use of integrated imaging and serum biomarker profiles to identify subclinical dysfunction in pediatric cancer patients treated with anthracyclines.

Toro-Salazar OH, Lee JH, Zellars KN, Perreault PE, Mason KC, Wang Z, Hor KN, Gillan E, Zeiss CJ, Gatti DM, Davey BT, Kutty S, Liang BT, Spinale FG.

Cardiooncology. 2018;4. pii: 4. doi: 10.1186/s40959-018-0030-5. Epub 2018 May 1.

3.

Genome-wide association for testis weight in the diversity outbred mouse population.

Yuan JT, Gatti DM, Philip VM, Kasparek S, Kreuzman AM, Mansky B, Sharif K, Taterra D, Taylor WM, Thomas M, Ward JO, Holmes A, Chesler EJ, Parker CC.

Mamm Genome. 2018 Jun;29(5-6):310-324. doi: 10.1007/s00335-018-9745-8. Epub 2018 Apr 24.

PMID:
29691636
4.

Genetic Drivers of Pancreatic Islet Function.

Keller MP, Gatti DM, Schueler KL, Rabaglia ME, Stapleton DS, Simecek P, Vincent M, Allen S, Broman AT, Bacher R, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD.

Genetics. 2018 May;209(1):335-356. doi: 10.1534/genetics.118.300864. Epub 2018 Mar 22.

PMID:
29567659
5.

Developmental constraint through negative pleiotropy in the zygomatic arch.

Percival CJ, Green R, Roseman CC, Gatti DM, Morgan JL, Murray SA, Donahue LR, Mayeux JM, Pollard KM, Hua K, Pomp D, Marcucio R, Hallgrímsson B.

Evodevo. 2018 Jan 27;9:3. doi: 10.1186/s13227-018-0092-3. eCollection 2018.

6.

Quantitative trait mapping in Diversity Outbred mice identifies two genomic regions associated with heart size.

Shorter JR, Huang W, Beak JY, Hua K, Gatti DM, de Villena FP, Pomp D, Jensen BC.

Mamm Genome. 2018 Feb;29(1-2):80-89. doi: 10.1007/s00335-017-9730-7. Epub 2017 Dec 26.

PMID:
29279960
7.

Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats.

Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal A, Francic S, Cui L, Gatti DM, Broman KW, Tschannen M, Tsaih SW, Zagloul M, Kim Y, Baur B, Fox J, Robinson M, Levy S, Flister MJ, Mott R, Valdar W, Solberg Woods LC.

Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28.

8.

Genetic background influences susceptibility to chemotherapy-induced hematotoxicity.

Gatti DM, Weber SN, Goodwin NC, Lammert F, Churchill GA.

Pharmacogenomics J. 2018 Apr;18(2):319-330. doi: 10.1038/tpj.2017.23. Epub 2017 Jun 13.

9.

CloudNeo: a cloud pipeline for identifying patient-specific tumor neoantigens.

Bais P, Namburi S, Gatti DM, Zhang X, Chuang JH.

Bioinformatics. 2017 Oct 1;33(19):3110-3112. doi: 10.1093/bioinformatics/btx375.

10.

Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice.

Tyler AL, Ji B, Gatti DM, Munger SC, Churchill GA, Svenson KL, Carter GW.

Genetics. 2017 Jun;206(2):621-639. doi: 10.1534/genetics.116.198051.

11.

Structural Variation Shapes the Landscape of Recombination in Mouse.

Morgan AP, Gatti DM, Najarian ML, Keane TM, Galante RJ, Pack AI, Mott R, Churchill GA, de Villena FP.

Genetics. 2017 Jun;206(2):603-619. doi: 10.1534/genetics.116.197988.

12.

Block network mapping approach to quantitative trait locus analysis.

Shreif ZZ, Gatti DM, Periwal V.

BMC Bioinformatics. 2016 Dec 22;17(1):544. doi: 10.1186/s12859-016-1351-8.

13.

Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer.

Winter JM, Gildea DE, Andreas JP, Gatti DM, Williams KA, Lee M, Hu Y, Zhang S; NISC Comparative Sequencing Program, Mullikin JC, Wolfsberg TG, McDonnell SK, Fogarty ZC, Larson MC, French AJ, Schaid DJ, Thibodeau SN, Churchill GA, Crawford NP.

Cell Syst. 2017 Jan 25;4(1):31-45.e6. doi: 10.1016/j.cels.2016.10.018. Epub 2016 Dec 1.

14.

Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection.

Chesler EJ, Gatti DM, Morgan AP, Strobel M, Trepanier L, Oberbeck D, McWeeney S, Hitzemann R, Ferris M, McMullan R, Clayshultle A, Bell TA, Manuel de Villena FP, Churchill GA.

G3 (Bethesda). 2016 Dec 7;6(12):3893-3902. doi: 10.1534/g3.116.035527.

15.

Defining the consequences of genetic variation on a proteome-wide scale.

Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SP.

Nature. 2016 Jun 23;534(7608):500-5. doi: 10.1038/nature18270. Epub 2016 Jun 15.

16.

R2d2 Drives Selfish Sweeps in the House Mouse.

Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, French JE, Gabriel SI, Gatti DM, Garland T Jr, Giagia-Athanasopoulou EB, Giménez MD, Grize SA, Gündüz İ, Holmes A, Hauffe HC, Herman JS, Holt JM, Hua K, Jolley WJ, Lindholm AK, López-Fuster MJ, Mitsainas G, da Luz Mathias M, McMillan L, Ramalhinho Mda G, Rehermann B, Rosshart SP, Searle JB, Shiao MS, Solano E, Svenson KL, Thomas-Laemont P, Threadgill DW, Ventura J, Weinstock GM, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

Mol Biol Evol. 2016 Jun;33(6):1381-95. doi: 10.1093/molbev/msw036. Epub 2016 Feb 15.

17.

Genetic Architectures of Quantitative Variation in RNA Editing Pathways.

Gu T, Gatti DM, Srivastava A, Snyder EM, Raghupathy N, Simecek P, Svenson KL, Dotu I, Chuang JH, Keller MP, Attie AD, Braun RE, Churchill GA.

Genetics. 2016 Feb;202(2):787-98. doi: 10.1534/genetics.115.179481. Epub 2015 Nov 27.

18.

Genetic properties of the MAGIC maize population: a new platform for high definition QTL mapping in Zea mays.

Dell'Acqua M, Gatti DM, Pea G, Cattonaro F, Coppens F, Magris G, Hlaing AL, Aung HH, Nelissen H, Baute J, Frascaroli E, Churchill GA, Inzé D, Morgante M, Pè ME.

Genome Biol. 2015 Sep 11;16:167. doi: 10.1186/s13059-015-0716-z.

19.

Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice.

Niazi MK, Dhulekar N, Schmidt D, Major S, Cooper R, Abeijon C, Gatti DM, Kramnik I, Yener B, Gurcan M, Beamer G.

Dis Model Mech. 2015 Sep;8(9):1141-53. doi: 10.1242/dmm.020867. Epub 2015 Jul 23.

20.

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T Jr, Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O'Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

PLoS Genet. 2015 Feb 13;11(2):e1004850. doi: 10.1371/journal.pgen.1004850. eCollection 2015 Feb.

21.

Diet dominates host genotype in shaping the murine gut microbiota.

Carmody RN, Gerber GK, Luevano JM Jr, Gatti DM, Somes L, Svenson KL, Turnbaugh PJ.

Cell Host Microbe. 2015 Jan 14;17(1):72-84. doi: 10.1016/j.chom.2014.11.010. Epub 2014 Dec 18.

22.

Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice.

Church RJ, Gatti DM, Urban TJ, Long N, Yang X, Shi Q, Eaddy JS, Mosedale M, Ballard S, Churchill GA, Navarro V, Watkins PB, Threadgill DW, Harrill AH.

Food Chem Toxicol. 2015 Feb;76:19-26. doi: 10.1016/j.fct.2014.11.008. Epub 2014 Nov 28.

23.

Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity.

French JE, Gatti DM, Morgan DL, Kissling GE, Shockley KR, Knudsen GA, Shepard KG, Price HC, King D, Witt KL, Pedersen LC, Munger SC, Svenson KL, Churchill GA.

Environ Health Perspect. 2015 Mar;123(3):237-45. doi: 10.1289/ehp.1408202. Epub 2014 Nov 6.

24.

High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis.

Smallwood TL, Gatti DM, Quizon P, Weinstock GM, Jung KC, Zhao L, Hua K, Pomp D, Bennett BJ.

G3 (Bethesda). 2014 Oct 23;4(12):2353-63. doi: 10.1534/g3.114.014704.

25.

Quantitative trait locus mapping methods for diversity outbred mice.

Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA.

G3 (Bethesda). 2014 Sep 18;4(9):1623-33. doi: 10.1534/g3.114.013748.

26.

Rapid identification of major-effect genes using the collaborative cross.

Ram R, Mehta M, Balmer L, Gatti DM, Morahan G.

Genetics. 2014 Sep;198(1):75-86. doi: 10.1534/genetics.114.163014.

27.

RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations.

Munger SC, Raghupathy N, Choi K, Simons AK, Gatti DM, Hinerfeld DA, Svenson KL, Keller MP, Attie AD, Hibbs MA, Graber JH, Chesler EJ, Churchill GA.

Genetics. 2014 Sep;198(1):59-73. doi: 10.1534/genetics.114.165886.

28.

Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1.

Yuan R, Gatti DM, Krier R, Malay E, Schultz D, Peters LL, Churchill GA, Harrison DE, Paigen B.

J Gerontol A Biol Sci Med Sci. 2015 Jul;70(7):817-26. doi: 10.1093/gerona/glu114. Epub 2014 Jul 28.

29.

Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene.

Recla JM, Robledo RF, Gatti DM, Bult CJ, Churchill GA, Chesler EJ.

Mamm Genome. 2014 Jun;25(5-6):211-22. doi: 10.1007/s00335-014-9508-0. Epub 2014 Apr 5.

30.

High-precision genetic mapping of behavioral traits in the diversity outbred mouse population.

Logan RW, Robledo RF, Recla JM, Philip VM, Bubier JA, Jay JJ, Harwood C, Wilcox T, Gatti DM, Bult CJ, Churchill GA, Chesler EJ.

Genes Brain Behav. 2013 Jun;12(4):424-37. doi: 10.1111/gbb.12029. Epub 2013 Mar 20.

31.

The Diversity Outbred mouse population.

Churchill GA, Gatti DM, Munger SC, Svenson KL.

Mamm Genome. 2012 Oct;23(9-10):713-8. doi: 10.1007/s00335-012-9414-2. Epub 2012 Aug 15.

32.

High-resolution genetic mapping using the Mouse Diversity outbred population.

Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA.

Genetics. 2012 Feb;190(2):437-47. doi: 10.1534/genetics.111.132597.

33.

MicroRNA expression in the livers of inbred mice.

Gatti DM, Lu L, Williams RW, Sun W, Wright FA, Threadgill DW, Rusyn I.

Mutat Res. 2011 Sep 1;714(1-2):126-33. doi: 10.1016/j.mrfmmm.2011.05.007. Epub 2011 May 14.

34.

Heading down the wrong pathway: on the influence of correlation within gene sets.

Gatti DM, Barry WT, Nobel AB, Rusyn I, Wright FA.

BMC Genomics. 2010 Oct 18;11:574. doi: 10.1186/1471-2164-11-574.

35.

Toxicogenetics: population-based testing of drug and chemical safety in mouse models.

Rusyn I, Gatti DM, Wiltshire T, Kleeberger SR, Threadgill DW.

Pharmacogenomics. 2010 Aug;11(8):1127-36. doi: 10.2217/pgs.10.100. Review. Erratum in: Pharmacogenomics. 2010 Sep;11(9):1344. Wilshire, Timothy [corrected to Wiltshire, Timothy].

36.

Sex-specific gene expression in the BXD mouse liver.

Gatti DM, Zhao N, Chesler EJ, Bradford BU, Shabalin AA, Yordanova R, Lu L, Rusyn I.

Physiol Genomics. 2010 Aug;42(3):456-68. doi: 10.1152/physiolgenomics.00110.2009. Epub 2010 Jun 15.

37.

Replication and narrowing of gene expression quantitative trait loci using inbred mice.

Gatti DM, Harrill AH, Wright FA, Threadgill DW, Rusyn I.

Mamm Genome. 2009 Jul;20(7):437-46. doi: 10.1007/s00335-009-9199-0. Epub 2009 Jul 17.

38.

Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel.

Harrill AH, Ross PK, Gatti DM, Threadgill DW, Rusyn I.

Toxicol Sci. 2009 Jul;110(1):235-43. doi: 10.1093/toxsci/kfp096. Epub 2009 May 6.

39.

Time-course comparison of xenobiotic activators of CAR and PPARalpha in mouse liver.

Ross PK, Woods CG, Bradford BU, Kosyk O, Gatti DM, Cunningham ML, Rusyn I.

Toxicol Appl Pharmacol. 2009 Mar 1;235(2):199-207. doi: 10.1016/j.taap.2008.12.011. Epub 2008 Dec 24.

40.

SAFEGUI: resampling-based tests of categorical significance in gene expression data made easy.

Gatti DM, Sypa M, Rusyn I, Wright FA, Barry WT.

Bioinformatics. 2009 Feb 15;25(4):541-2. doi: 10.1093/bioinformatics/btn655. Epub 2008 Dec 19.

41.

FastMap: fast eQTL mapping in homozygous populations.

Gatti DM, Shabalin AA, Lam TC, Wright FA, Rusyn I, Nobel AB.

Bioinformatics. 2009 Feb 15;25(4):482-9. doi: 10.1093/bioinformatics/btn648. Epub 2008 Dec 17.

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