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Bayesian group sequential designs for phase III emergency medicine trials: a case study using the PARAMEDIC2 trial.

Ryan EG, Stallard N, Lall R, Ji C, Perkins GD, Gates S.

Trials. 2020 Jan 14;21(1):84. doi: 10.1186/s13063-019-4024-x.


Bayesian adaptive designs for multi-arm trials: an orthopaedic case study.

Ryan EG, Lamb SE, Williamson E, Gates S.

Trials. 2020 Jan 14;21(1):83. doi: 10.1186/s13063-019-4021-0.


The influence of time to adrenaline administration in the Paramedic 2 randomised controlled trial.

Perkins GD, Kenna C, Ji C, Deakin CD, Nolan JP, Quinn T, Scomparin C, Fothergill R, Gunson I, Pocock H, Rees N, O'Shea L, Finn J, Gates S, Lall R.

Intensive Care Med. 2020 Jan 7. doi: 10.1007/s00134-019-05836-2. [Epub ahead of print]


Comparison of Bayesian and frequentist group-sequential clinical trial designs.

Stallard N, Todd S, Ryan EG, Gates S.

BMC Med Res Methodol. 2020 Jan 7;20(1):4. doi: 10.1186/s12874-019-0892-8.


Association of a P2RX7 gene missense variant with brachycephalic dog breeds.

Sophocleous RA, Sluyter V, Curtis BL, Curtis SJ, Jurak LM, Faulks M, Spildrejorde M, Gates S, Proctor EJ, Seavers A, Watson D, Kuit T, Dowton M, Stokes L, Sluyter R.

Anim Genet. 2020 Feb;51(1):127-131. doi: 10.1111/age.12884. Epub 2019 Nov 27.


Life-threatening hypersensitivity pneumonitis secondary to e-cigarettes.

Nair N, Hurley M, Gates S, Davies P, Chen IL, Todd I, Fairclough L, Bush A, Bhatt JM.

Arch Dis Child. 2019 Nov 11. pii: archdischild-2019-317889. doi: 10.1136/archdischild-2019-317889. [Epub ahead of print]


Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing.

Blythe EE, Gates SN, Deshaies RJ, Martin A.

Structure. 2019 Dec 3;27(12):1820-1829.e4. doi: 10.1016/j.str.2019.09.011. Epub 2019 Oct 14.


Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP-dependent substrate translocation.

Gates SN, Martin A.

Protein Sci. 2020 Feb;29(2):407-419. doi: 10.1002/pro.3743. Epub 2019 Oct 17. Review.


Approaches to protect and maintain health care services in armed conflict - meeting SDGs 3 and 16.

Druce P, Bogatyreva E, Siem FF, Gates S, Kaade H, Sundby J, Rostrup M, Andersen C, Rustad SCA, Tchie A, Mood R, Nygård HM, Urdal H, Winkler AS.

Confl Health. 2019 Jan 29;13:2. doi: 10.1186/s13031-019-0186-0. eCollection 2019.


Outcomes of Posterior Glenoid Bone-Grafting in Anatomical Total Shoulder Arthroplasty: A Systematic Review.

Gates S, Cutler H, Khazzam M.

JBJS Rev. 2019 Sep;7(9):e6. doi: 10.2106/JBJS.RVW.19.00005.


Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT.

Perkins GD, Mistry D, Lall R, Gao-Smith F, Snelson C, Hart N, Camporota L, Varley J, Carle C, Paramasivam E, Hoddell B, de Paeztron A, Dosanjh S, Sampson J, Blair L, Couper K, McAuley D, Young JD, Walsh T, Blackwood B, Rose L, Lamb SE, Dritsaki M, Maredza M, Khan I, Petrou S, Gates S.

Health Technol Assess. 2019 Sep;23(48):1-114. doi: 10.3310/hta23480.


Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity.

Tariq A, Lin J, Jackrel ME, Hesketh CD, Carman PJ, Mack KL, Weitzman R, Gambogi C, Hernandez Murillo OA, Sweeny EA, Gurpinar E, Yokom AL, Gates SN, Yee K, Sudesh S, Stillman J, Rizo AN, Southworth DR, Shorter J.

Cell Rep. 2019 Aug 20;28(8):2080-2095.e6. doi: 10.1016/j.celrep.2019.07.069.


Use of Mass Communication by Public Health Programs in Nonmetropolitan Regions.

Kreslake JM, Elkins A, Thomas CN, Gates S, Lehman T.

Prev Chronic Dis. 2019 Jul 25;16:E96. doi: 10.5888/pcd16.190014. No abstract available.


Innervation of the subscapularis: an anatomic study.

Sager B, Gates S, Collett G, Chhabra A, Khazzam M.

JSES Open Access. 2019 Apr 26;3(2):65-69. doi: 10.1016/j.jses.2019.02.001. eCollection 2019 Jul.


Positive Patient Response to a Structured Exercise Program Delivered in Inpatient Psychiatry.

Tomasi D, Gates S, Reyns E.

Glob Adv Health Med. 2019 May 21;8:2164956119848657. doi: 10.1177/2164956119848657. eCollection 2019.


Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.

Rizo AN, Lin J, Gates SN, Tse E, Bart SM, Castellano LM, DiMaio F, Shorter J, Southworth DR.

Nat Commun. 2019 Jun 3;10(1):2393. doi: 10.1038/s41467-019-10150-y.


The effects of adrenaline in out of hospital cardiac arrest with shockable and non-shockable rhythms: Findings from the PACA and PARAMEDIC-2 randomised controlled trials.

Perkins GD, Kenna C, Ji C, Deakin CD, Nolan JP, Quinn T, Fothergill R, Gunson I, Pocock H, Rees N, Charlton K, Finn J, Gates S, Lall R.

Resuscitation. 2019 Jul;140:55-63. doi: 10.1016/j.resuscitation.2019.05.007. Epub 2019 May 19.


Using Bayesian adaptive designs to improve phase III trials: a respiratory care example.

Ryan EG, Bruce J, Metcalfe AJ, Stallard N, Lamb SE, Viele K, Young D, Gates S.

BMC Med Res Methodol. 2019 May 14;19(1):99. doi: 10.1186/s12874-019-0739-3.


Count me in: using a patient portal to minimize implicit bias in clinical research recruitment.

Kannan V, Wilkinson KE, Varghese M, Lynch-Medick S, Willett DL, Bosler TA, Chu L, Gates SI, Holbein MEB, Willett MM, Reimold SC, Toto RD.

J Am Med Inform Assoc. 2019 Aug 1;26(8-9):703-713. doi: 10.1093/jamia/ocz038.


A Rare Case of Human Papillomavirus-associated High-grade Neuroendocrine Carcinoma of the Hypopharynx.

Sanwal C, Voorhees G, Moon A, Turner T, Gates SL.

Cureus. 2019 Feb 26;11(2):e4138. doi: 10.7759/cureus.4138.


Clinical Scenarios of the Application of Electrical Impedance Tomography in Paediatric Intensive Care.

Davies P, Yasin S, Gates S, Bird D, Silvestre C.

Sci Rep. 2019 Mar 29;9(1):5362. doi: 10.1038/s41598-019-41774-1.


The mystery of our mathematical universe.

Paulson S, Gates SJ Jr, Wertheim M.

Ann N Y Acad Sci. 2019 Dec;1458(1):9-25. doi: 10.1111/nyas.14026. Epub 2019 Mar 22.


Mobile Device Applications for Electronic Patient Portals in Oncology.

Pho KK, Lu R, Gates S, Cai J, Xie D, Xie Y, Lee SJC, Gerber DE.

JCO Clin Cancer Inform. 2019 Feb;3:1-8. doi: 10.1200/CCI.18.00094.


HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis.

Corleis B, Bucsan AN, Deruaz M, Vrbanac VD, Lisanti-Park AC, Gates SJ, Linder AH, Paer JM, Olson GS, Bowman BA, Schiff AE, Medoff BD, Tager AM, Luster AD, Khader SA, Kaushal D, Kwon DS.

Cell Rep. 2019 Feb 5;26(6):1409-1418.e5. doi: 10.1016/j.celrep.2019.01.021.


Adrenaline and vasopressin for cardiac arrest.

Finn J, Jacobs I, Williams TA, Gates S, Perkins GD.

Cochrane Database Syst Rev. 2019 Jan 17;1:CD003179. doi: 10.1002/14651858.CD003179.pub2.


Non-invasive ventilation as a strategy for weaning from invasive mechanical ventilation: a systematic review and Bayesian meta-analysis.

Yeung J, Couper K, Ryan EG, Gates S, Hart N, Perkins GD.

Intensive Care Med. 2018 Dec;44(12):2192-2204. doi: 10.1007/s00134-018-5434-z. Epub 2018 Oct 31.


Effect of Protocolized Weaning With Early Extubation to Noninvasive Ventilation vs Invasive Weaning on Time to Liberation From Mechanical Ventilation Among Patients With Respiratory Failure: The Breathe Randomized Clinical Trial.

Perkins GD, Mistry D, Gates S, Gao F, Snelson C, Hart N, Camporota L, Varley J, Carle C, Paramasivam E, Hoddell B, McAuley DF, Walsh TS, Blackwood B, Rose L, Lamb SE, Petrou S, Young D, Lall R; Breathe Collaborators.

JAMA. 2018 Nov 13;320(18):1881-1888. doi: 10.1001/jama.2018.13763.


Substrate-engaged 26S proteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.

de la Peña AH, Goodall EA, Gates SN, Lander GC, Martin A.

Science. 2018 Nov 30;362(6418). pii: eaav0725. doi: 10.1126/science.aav0725. Epub 2018 Oct 11.


Diagnostic Accuracy of the Scapular Retraction Test in Assessing the Status of the Rotator Cuff.

Khazzam M, Gates ST, Tisano BK, Kukowski N.

Orthop J Sports Med. 2018 Oct 4;6(10):2325967118799308. doi: 10.1177/2325967118799308. eCollection 2018 Oct.


Electrical impedance tomography effectively used in a case of paediatric pulmonary Langerhans cell histiocytosis.

Davies P, Gates S, Grundy R.

BMJ Case Rep. 2018 Sep 5;2018. pii: bcr-2017-224040. doi: 10.1136/bcr-2017-224040.


Feasibility of data linkage in the PARAMEDIC trial: a cluster randomised trial of mechanical chest compression in out-of-hospital cardiac arrest.

Ji C, Quinn T, Gavalova L, Lall R, Scomparin C, Horton J, Deakin CD, Pocock H, Smyth MA, Rees N, Brace-McDonnell SJ, Gates S, Perkins GD.

BMJ Open. 2018 Jul 28;8(7):e021519. doi: 10.1136/bmjopen-2018-021519.


A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest.

Perkins GD, Ji C, Deakin CD, Quinn T, Nolan JP, Scomparin C, Regan S, Long J, Slowther A, Pocock H, Black JJM, Moore F, Fothergill RT, Rees N, O'Shea L, Docherty M, Gunson I, Han K, Charlton K, Finn J, Petrou S, Stallard N, Gates S, Lall R; PARAMEDIC2 Collaborators.

N Engl J Med. 2018 Aug 23;379(8):711-721. doi: 10.1056/NEJMoa1806842. Epub 2018 Jul 18.


Correlation between neonatal outcomes of twins depends on the outcome: secondary analysis of twelve randomised controlled trials.

Yelland LN, Schuit E, Zamora J, Middleton PF, Lim AC, Nassar AH, Rode L, Serra V, Thom EA, Vayssière C, Mol B, Gates S.

BJOG. 2018 Oct;125(11):1406-1413. doi: 10.1111/1471-0528.15292. Epub 2018 Jun 25.


A call for more science in forensic science.

Bell S, Sah S, Albright TD, Gates SJ Jr, Denton MB, Casadevall A.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4541-4544. doi: 10.1073/pnas.1712161115. Epub 2018 Apr 12.


Predictors of metformin failure in gestational diabetes mellitus (GDM).

Khin MO, Gates S, Saravanan P.

Diabetes Metab Syndr. 2018 May;12(3):405-410. doi: 10.1016/j.dsx.2018.01.003. Epub 2018 Jan 31.


Characteristics of Patients Using Patient Portals in Oncology.

Pho K, Lu R, Gates S, Xie Y, Lee SJC, Gerber DE.

JAMA Oncol. 2018 Mar 1;4(3):416-418. doi: 10.1001/jamaoncol.2017.5257. No abstract available.


What works in promoting and maintaining diversity in nursing programs.

Gates SA.

Nurs Forum. 2018 Apr;53(2):190-196. doi: 10.1111/nuf.12242. Epub 2018 Jan 23.


High Initial Sputter Rate Found for Vaccinia Virions Using Isotopic Labeling, NanoSIMS, and AFM.

Gates SD, Condit RC, Moussatche N, Stewart BJ, Malkin AJ, Weber PK.

Anal Chem. 2018 Feb 6;90(3):1613-1620. doi: 10.1021/acs.analchem.7b02786. Epub 2018 Jan 19.


Preparing Nursing and Social Work Students to Care for Patients in Acute Alcohol Withdrawal.

Gates SA, Brown JR.

J Addict Nurs. 2017 Jul/Sep;28(3):143-147. doi: 10.1097/JAN.0000000000000178.


Post-admission outcomes of participants in the PARAMEDIC trial: A cluster randomised trial of mechanical or manual chest compressions.

Ji C, Lall R, Quinn T, Kaye C, Haywood K, Horton J, Gordon V, Deakin CD, Pocock H, Carson A, Smyth M, Rees N, Han K, Byers S, Brace-McDonnell S, Gates S, Perkins GD; PARAMEDIC trial Collaborators.

Resuscitation. 2017 Sep;118:82-88. doi: 10.1016/j.resuscitation.2017.06.026. Epub 2017 Jul 5.


Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104.

Gates SN, Yokom AL, Lin J, Jackrel ME, Rizo AN, Kendsersky NM, Buell CE, Sweeny EA, Mack KL, Chuang E, Torrente MP, Su M, Shorter J, Southworth DR.

Science. 2017 Jul 21;357(6348):273-279. doi: 10.1126/science.aan1052. Epub 2017 Jun 15.


The cost-effectiveness of a mechanical compression device in out-of-hospital cardiac arrest.

Marti J, Hulme C, Ferreira Z, Nikolova S, Lall R, Kaye C, Smyth M, Kelly C, Quinn T, Gates S, Deakin CD, Perkins GD.

Resuscitation. 2017 Aug;117:1-7. doi: 10.1016/j.resuscitation.2017.04.036. Epub 2017 May 2.


Prehospital randomised assessment of a mechanical compression device in out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised trial and economic evaluation.

Gates S, Lall R, Quinn T, Deakin CD, Cooke MW, Horton J, Lamb SE, Slowther AM, Woollard M, Carson A, Smyth M, Wilson K, Parcell G, Rosser A, Whitfield R, Williams A, Jones R, Pocock H, Brock N, Black JJ, Wright J, Han K, Shaw G, Blair L, Marti J, Hulme C, McCabe C, Nikolova S, Ferreira Z, Perkins GD.

Health Technol Assess. 2017 Mar;21(11):1-176. doi: 10.3310/hta21110.


Application of the Uranium-Helium Chronometer to the Analysis of Nuclear Forensic Materials.

Gates SD, Cassata WS.

Anal Chem. 2016 Dec 20;88(24):12310-12315. doi: 10.1021/acs.analchem.6b03502. Epub 2016 Dec 6.


Characteristics of patients who are not resuscitated in out of hospital cardiac arrests and opportunities to improve community response to cardiac arrest.

Rajagopal S, Kaye CR, Lall R, Deakin CD, Gates S, Pocock H, Quinn T, Rees N, Smyth M, Perkins GD.

Resuscitation. 2016 Dec;109:110-115. doi: 10.1016/j.resuscitation.2016.09.014. Epub 2016 Oct 17.


Pre-hospital Assessment of the Role of Adrenaline: Measuring the Effectiveness of Drug administration In Cardiac arrest (PARAMEDIC-2): Trial protocol.

Perkins GD, Quinn T, Deakin CD, Nolan JP, Lall R, Slowther AM, Cooke M, Lamb SE, Petrou S, Achana F, Finn J, Jacobs IG, Carson A, Smyth M, Han K, Byers S, Rees N, Whitfield R, Moore F, Fothergill R, Stallard N, Long J, Hennings S, Horton J, Kaye C, Gates S.

Resuscitation. 2016 Nov;108:75-81. doi: 10.1016/j.resuscitation.2016.08.029. Epub 2016 Sep 17.


Increase in Cancer Center Staff Effort Related to Electronic Patient Portal Use.

Laccetti AL, Chen B, Cai J, Gates S, Xie Y, Lee SJ, Gerber DE.

J Oncol Pract. 2016 Dec;12(12):e981-e990. Epub 2016 Oct 31.


Polyphosphate: A Conserved Modifier of Amyloidogenic Processes.

Cremers CM, Knoefler D, Gates S, Martin N, Dahl JU, Lempart J, Xie L, Chapman MR, Galvan V, Southworth DR, Jakob U.

Mol Cell. 2016 Sep 1;63(5):768-80. doi: 10.1016/j.molcel.2016.07.016. Epub 2016 Aug 25.

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