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Items: 22

1.

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease.

Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T.

Nature. 2020 Jan;577(7790):399-404. doi: 10.1038/s41586-019-1895-7. Epub 2020 Jan 8.

PMID:
31915375
2.

Undulating changes in human plasma proteome profiles across the lifespan.

Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C, Milman S, Barzilai N, Wyss-Coray T.

Nat Med. 2019 Dec;25(12):1843-1850. doi: 10.1038/s41591-019-0673-2. Epub 2019 Dec 5.

PMID:
31806903
3.

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains.

Pluvinage JV, Haney MS, Smith BAH, Sun J, Iram T, Bonanno L, Li L, Lee DP, Morgens DW, Yang AC, Shuken SR, Gate D, Scott M, Khatri P, Luo J, Bertozzi CR, Bassik MC, Wyss-Coray T.

Nature. 2019 Apr;568(7751):187-192. doi: 10.1038/s41586-019-1088-4. Epub 2019 Apr 3.

4.

Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics.

Yang AC, du Bois H, Olsson N, Gate D, Lehallier B, Berdnik D, Brewer KD, Bertozzi CR, Elias JE, Wyss-Coray T.

J Am Chem Soc. 2018 Jun 13;140(23):7046-7051. doi: 10.1021/jacs.8b03074. Epub 2018 May 30.

5.

Interleukin-17A Promotes CD8+ T Cell Cytotoxicity To Facilitate West Nile Virus Clearance.

Acharya D, Wang P, Paul AM, Dai J, Gate D, Lowery JE, Stokic DS, Leis AA, Flavell RA, Town T, Fikrig E, Bai F.

J Virol. 2016 Dec 16;91(1). pii: e01529-16. doi: 10.1128/JVI.01529-16. Print 2017 Jan 1.

6.

CD8+ T Cells Play a Bystander Role in Mice Latently Infected with Herpes Simplex Virus 1.

Mott KR, Gate D, Matundan HH, Ghiasi YN, Town T, Ghiasi H.

J Virol. 2016 Apr 29;90(10):5059-5067. doi: 10.1128/JVI.00255-16. Print 2016 May 15.

7.

Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection.

Tseng CW, Biancotti JC, Berg BL, Gate D, Kolar SL, Müller S, Rodriguez MD, Rezai-Zadeh K, Fan X, Beenhouwer DO, Town T, Liu GY.

PLoS Pathog. 2015 Nov 30;11(11):e1005292. doi: 10.1371/journal.ppat.1005292. eCollection 2015.

8.

Characterization of cancer stem cells and primary cilia in medulloblastoma.

Gate D, Danielpour M, Bannykh S, Town T.

CNS Neurol Disord Drug Targets. 2015;14(5):600-11.

PMID:
25921740
9.

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

Guillot-Sestier MV, Doty KR, Gate D, Rodriguez J Jr, Leung BP, Rezai-Zadeh K, Town T.

Neuron. 2015 Feb 4;85(3):534-48. doi: 10.1016/j.neuron.2014.12.068. Epub 2015 Jan 22.

10.

MyD88 is dispensable for cerebral amyloidosis and neuroinflammation in APP/PS1 transgenic mice.

Weitz TM, Gate D, Rezai-Zadeh K, Town T.

Am J Pathol. 2014 Nov;184(11):2855-61. doi: 10.1016/j.ajpath.2014.07.004. Epub 2014 Aug 28.

11.

T-cell TGF-β signaling abrogation restricts medulloblastoma progression.

Gate D, Danielpour M, Rodriguez J Jr, Kim GB, Levy R, Bannykh S, Breunig JJ, Kaech SM, Flavell RA, Town T.

Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):E3458-66. doi: 10.1073/pnas.1412489111. Epub 2014 Jul 31.

12.

A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss.

Cohen RM, Rezai-Zadeh K, Weitz TM, Rentsendorj A, Gate D, Spivak I, Bholat Y, Vasilevko V, Glabe CG, Breunig JJ, Rakic P, Davtyan H, Agadjanyan MG, Kepe V, Barrio JR, Bannykh S, Szekely CA, Pechnick RN, Town T.

J Neurosci. 2013 Apr 10;33(15):6245-56. doi: 10.1523/JNEUROSCI.3672-12.2013.

13.

IL-22 signaling contributes to West Nile encephalitis pathogenesis.

Wang P, Bai F, Zenewicz LA, Dai J, Gate D, Cheng G, Yang L, Qian F, Yuan X, Montgomery RR, Flavell RA, Town T, Fikrig E.

PLoS One. 2012;7(8):e44153. doi: 10.1371/journal.pone.0044153. Epub 2012 Aug 28.

14.

Rapid genetic targeting of pial surface neural progenitors and immature neurons by neonatal electroporation.

Breunig JJ, Gate D, Levy R, Rodriguez J Jr, Kim GB, Danielpour M, Svendsen CN, Town T.

Neural Dev. 2012 Jul 10;7:26. doi: 10.1186/1749-8104-7-26.

15.

Basic biology and mechanisms of neural ciliogenesis and the B9 family.

Gate D, Danielpour M, Levy R, Breunig JJ, Town T.

Mol Neurobiol. 2012 Jun;45(3):564-70. doi: 10.1007/s12035-012-8276-7. Epub 2012 May 30. Review.

PMID:
22644387
16.

How to get from here to there: macrophage recruitment in Alzheimer's disease.

Rezai-Zadeh K, Gate D, Gowing G, Town T.

Curr Alzheimer Res. 2011 Mar;8(2):156-63. Review.

17.

The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1.

Allen SJ, Hamrah P, Gate D, Mott KR, Mantopoulos D, Zheng L, Town T, Jones C, von Andrian UH, Freeman GJ, Sharpe AH, BenMohamed L, Ahmed R, Wechsler SL, Ghiasi H.

J Virol. 2011 May;85(9):4184-97. doi: 10.1128/JVI.02290-10. Epub 2011 Feb 9.

18.

Macrophage IL-12p70 signaling prevents HSV-1-induced CNS autoimmunity triggered by autoaggressive CD4+ Tregs.

Mott KR, Gate D, Zandian M, Allen SJ, Rajasagi NK, van Rooijen N, Chen S, Arditi M, Rouse BT, Flavell RA, Town T, Ghiasi H.

Invest Ophthalmol Vis Sci. 2011 Apr 8;52(5):2321-33. doi: 10.1167/iovs.10-6536. Print 2011 Apr.

19.

Macrophages in Alzheimer's disease: the blood-borne identity.

Gate D, Rezai-Zadeh K, Jodry D, Rentsendorj A, Town T.

J Neural Transm (Vienna). 2010 Aug;117(8):961-70. doi: 10.1007/s00702-010-0422-7. Epub 2010 Jun 2. Review.

20.

Can peripheral leukocytes be used as Alzheimer's disease biomarkers?

Rezai-Zadeh K, Gate D, Szekely CA, Town T.

Expert Rev Neurother. 2009 Nov;9(11):1623-33. doi: 10.1586/ern.09.118. Review.

21.

IL-10 signaling blockade controls murine West Nile virus infection.

Bai F, Town T, Qian F, Wang P, Kamanaka M, Connolly TM, Gate D, Montgomery RR, Flavell RA, Fikrig E.

PLoS Pathog. 2009 Oct;5(10):e1000610. doi: 10.1371/journal.ppat.1000610. Epub 2009 Oct 9.

22.

CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?

Rezai-Zadeh K, Gate D, Town T.

J Neuroimmune Pharmacol. 2009 Dec;4(4):462-75. doi: 10.1007/s11481-009-9166-2. Epub 2009 Aug 11. Review.

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