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Items: 31

1.

Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma.

Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BD; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2018 Aug 3;3(26). pii: eaao4747. doi: 10.1126/sciimmunol.aao4747.

PMID:
30076281
2.

Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort.

Ash SY, Rahaghi FN, Come CE, Ross JC, Colon AG, Cardet-Guisasola JC, Dunican EM, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Mauger DT, Wenzel SE, Levy BD, San Jose Estepar R, Israel E, Washko GR; SARP Investigators.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):39-50. doi: 10.1164/rccm.201712-2426OC.

PMID:
29672122
3.

Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma.

DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, Meyers D, Bleecker ER, Castro M, Coverstone AM, Bacharier LB, Jarjour NN, Sorkness RL, Ramratnam S, Irani AM, Israel E, Levy B, Phipatanakul W, Gaffin JM, Gerald Teague W.

BMC Pulm Med. 2018 Apr 10;18(1):58. doi: 10.1186/s12890-018-0612-x.

4.

ALX receptor ligands define a biochemical endotype for severe asthma.

Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program- Investigators.

JCI Insight. 2018 Mar 22;3(6). pii: 120932. doi: 10.1172/jci.insight.120932. [Epub ahead of print] No abstract available.

5.

Conjugation of nitrated acetaminophen to Der p1 amplifies peripheral blood monocyte response to Der p1.

Thomas RG, Rivera Reyes BM, Gaston BM, Rivera Acosta NB, Bederman IR, Smith LA, Sutton MT, Wang B, Hunt JF, Bonfield TL.

PLoS One. 2017 Dec 11;12(12):e0188614. doi: 10.1371/journal.pone.0188614. eCollection 2017.

6.

Bacterial infections in patients with primary ciliary dyskinesia: Comparison with cystic fibrosis.

Wijers CD, Chmiel JF, Gaston BM.

Chron Respir Dis. 2017 Nov;14(4):392-406. doi: 10.1177/1479972317694621. Epub 2017 Mar 6. Review.

7.

Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.

Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN.

J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):545-554.e4. doi: 10.1016/j.jaip.2017.05.032. Epub 2017 Aug 31.

8.

Natural killer cell-mediated inflammation resolution is disabled in severe asthma.

Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2017 Mar 10;2(9). pii: eaam5446. doi: 10.1126/sciimmunol.aam5446.

9.

ALX receptor ligands define a biochemical endotype for severe asthma.

Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators.

JCI Insight. 2017 Jul 20;2(14). pii: 93534. doi: 10.1172/jci.insight.93534. [Epub ahead of print]

10.

Gene Expression Correlated with Severe Asthma Characteristics Reveals Heterogeneous Mechanisms of Severe Disease.

Modena BD, Bleecker ER, Busse WW, Erzurum SC, Gaston BM, Jarjour NN, Meyers DA, Milosevic J, Tedrow JR, Wu W, Kaminski N, Wenzel SE.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1449-1463. doi: 10.1164/rccm.201607-1407OC.

11.

Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma.

Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, Jarjour NN, Levy BD, Peters SP, Teague WG, Fajt M, Wenzel SE, Erzurum SC, Israel E; Severe Asthma Research Program.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1439-1448. doi: 10.1164/rccm.201607-1453OC.

12.

Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012.

Zein JG, Udeh BL, Teague WG, Koroukian SM, Schlitz NK, Bleecker ER, Busse WB, Calhoun WJ, Castro M, Comhair SA, Fitzpatrick AM, Israel E, Wenzel SE, Holguin F, Gaston BM, Erzurum SC; Severe Asthma Research Program.

PLoS One. 2016 Jun 13;11(6):e0157301. doi: 10.1371/journal.pone.0157301. eCollection 2016.

13.

Future Research Directions in Asthma. An NHLBI Working Group Report.

Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA Jr, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC.

Am J Respir Crit Care Med. 2015 Dec 1;192(11):1366-72. doi: 10.1164/rccm.201505-0963WS. Review.

14.

Asthma Is More Severe in Older Adults.

Zein JG, Dweik RA, Comhair SA, Bleecker ER, Moore WC, Peters SP, Busse WW, Jarjour NN, Calhoun WJ, Castro M, Chung KF, Fitzpatrick A, Israel E, Teague WG, Wenzel SE, Love TE, Gaston BM, Erzurum SC; Severe Asthma Research Program.

PLoS One. 2015 Jul 22;10(7):e0133490. doi: 10.1371/journal.pone.0133490. eCollection 2015.

15.

Obstructive Sleep Apnea Risk, Asthma Burden, and Lower Airway Inflammation in Adults in the Severe Asthma Research Program (SARP) II.

Teodorescu M, Broytman O, Curran-Everett D, Sorkness RL, Crisafi G, Bleecker ER, Erzurum S, Gaston BM, Wenzel SE, Jarjour NN; National Institutes of Health, National Heart, Lung and Blood Institute Severe Asthma Research Program (SARP) Investigators.

J Allergy Clin Immunol Pract. 2015 Jul-Aug;3(4):566-75.e1. doi: 10.1016/j.jaip.2015.04.002. Epub 2015 May 21.

16.

Detection of S-nitroso compounds by use of midinfrared cavity ring-down spectroscopy.

Stsiapura VI, Shuali VK, Gaston BM, Lehmann KK.

Anal Chem. 2015 Mar 17;87(6):3345-53. doi: 10.1021/ac5045143. Epub 2015 Mar 3.

17.

Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways.

Modena BD, Tedrow JR, Milosevic J, Bleecker ER, Meyers DA, Wu W, Bar-Joseph Z, Erzurum SC, Gaston BM, Busse WW, Jarjour NN, Kaminski N, Wenzel SE.

Am J Respir Crit Care Med. 2014 Dec 15;190(12):1363-72. doi: 10.1164/rccm.201406-1099OC.

18.

Biomarkers in asthma: a real hope to better manage asthma.

Erzurum SC, Gaston BM.

Clin Chest Med. 2012 Sep;33(3):459-71. doi: 10.1016/j.ccm.2012.06.007. Epub 2012 Jul 25. Review.

19.

Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program.

Jarjour NN, Erzurum SC, Bleecker ER, Calhoun WJ, Castro M, Comhair SA, Chung KF, Curran-Everett D, Dweik RA, Fain SB, Fitzpatrick AM, Gaston BM, Israel E, Hastie A, Hoffman EA, Holguin F, Levy BD, Meyers DA, Moore WC, Peters SP, Sorkness RL, Teague WG, Wenzel SE, Busse WW; NHLBI Severe Asthma Research Program (SARP).

Am J Respir Crit Care Med. 2012 Feb 15;185(4):356-62. doi: 10.1164/rccm.201107-1317PP. Epub 2011 Nov 17.

20.

Detrimental effects of environmental tobacco smoke in relation to asthma severity.

Comhair SA, Gaston BM, Ricci KS, Hammel J, Dweik RA, Teague WG, Meyers D, Ampleford EJ, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Israel E, Jarjour WN, Moore W, Peters SP, Wenzel S, Hazen SL, Erzurum SC; National Heart Lung Blood Institute Severe Asthma Research Program.

PLoS One. 2011 May 4;6(5):e18574. doi: 10.1371/journal.pone.0018574.

21.

Increased systemic inflammation overnight correlates with insulin resistance among children evaluated for obstructive sleep apnea.

Deboer MD, Mendoza JP, Liu L, Ford G, Yu PL, Gaston BM.

Sleep Breath. 2012 Jun;16(2):349-54. doi: 10.1007/s11325-011-0499-8. Epub 2011 Mar 1.

22.

Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program.

Fitzpatrick AM, Teague WG, Meyers DA, Peters SP, Li X, Li H, Wenzel SE, Aujla S, Castro M, Bacharier LB, Gaston BM, Bleecker ER, Moore WC; National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program.

J Allergy Clin Immunol. 2011 Feb;127(2):382-389.e1-13. doi: 10.1016/j.jaci.2010.11.015. Epub 2010 Dec 31.

23.

A neonatal mouse model of intestinal perforation: investigating the harmful synergism between glucocorticoids and indomethacin.

Gordon PV, Herman AC, Marcinkiewicz M, Gaston BM, Laubach VE, Aschner JL.

J Pediatr Gastroenterol Nutr. 2007 Nov;45(5):509-19.

PMID:
18030227
24.

Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation.

Sorkness RL, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Erzurum SC, Gaston BM, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Wenzel SE; National Heart, Lung, and Blood Institute Severe Asthma Research Program.

J Appl Physiol (1985). 2008 Feb;104(2):394-403. Epub 2007 Nov 8.

25.

Features of severe asthma in school-age children: Atopy and increased exhaled nitric oxide.

Fitzpatrick AM, Gaston BM, Erzurum SC, Teague WG; National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program.

J Allergy Clin Immunol. 2006 Dec;118(6):1218-25. Epub 2006 Oct 10.

26.

Exhaled-breath condensate pH can be safely and continuously monitored in mechanically ventilated patients.

Walsh BK, Mackey DJ, Pajewski T, Yu Y, Gaston BM, Hunt JF.

Respir Care. 2006 Oct;51(10):1125-31.

27.

S-nitrosylation signaling in cell biology.

Gaston BM, Carver J, Doctor A, Palmer LA.

Mol Interv. 2003 Aug;3(5):253-63. Review.

PMID:
14993439
28.

Hemoglobin and nitric oxide.

Gaston BM, Hare JM.

N Engl J Med. 2003 Jul 24;349(4):402-5; author reply 402-5. No abstract available.

PMID:
12879897
29.

Emissions testing for children, chapter 2: carbon monoxide.

Gaston BM.

J Pediatr. 1999 Nov;135(5):537-8. No abstract available.

PMID:
10547237
30.

Perinatal unilateral hydrocephalus. Atresia of the foramen of Monro.

Gaston BM, Jones BE.

Pediatr Radiol. 1989;19(5):328-9.

PMID:
2666938
31.

Weight change underway and in port in the American Navy.

Gaston BM.

Int J Obes. 1989;13(5):619-23.

PMID:
2583916

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