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Items: 31

1.

Differential Roles of Lipin1 and Lipin2 in the Hepatitis C Virus Replication Cycle.

Castro V, Calvo G, Ávila-Pérez G, Dreux M, Gastaminza P.

Cells. 2019 Nov 18;8(11). pii: E1456. doi: 10.3390/cells8111456.

2.

A Cell Culture Model for Persistent HCV Infection.

Castro V, Ávila-Pérez G, Mingorance L, Gastaminza P.

Methods Mol Biol. 2019;1911:157-168. doi: 10.1007/978-1-4939-8976-8_10.

PMID:
30593624
3.

Host phosphatidic acid phosphatase lipin1 is rate limiting for functional hepatitis C virus replicase complex formation.

Mingorance L, Castro V, Ávila-Pérez G, Calvo G, Rodriguez MJ, Carrascosa JL, Pérez-Del-Pulgar S, Forns X, Gastaminza P.

PLoS Pathog. 2018 Sep 18;14(9):e1007284. doi: 10.1371/journal.ppat.1007284. eCollection 2018 Sep.

4.

Permissiveness of human hepatocellular carcinoma cell lines for hepatitis C virus entry and replication.

Coto-Llerena M, Koutsoudakis G, Boix L, López-Oliva JM, Caro-Pérez N, Fernández-Carrillo C, González P, Gastaminza P, Bruix J, Forns X, Pérez-Del-Pulgar S.

Virus Res. 2017 Aug 15;240:35-46. doi: 10.1016/j.virusres.2017.07.018. Epub 2017 Jul 24.

PMID:
28751105
5.

Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment.

Moreno E, Gallego I, Gregori J, Lucía-Sanz A, Soria ME, Castro V, Beach NM, Manrubia S, Quer J, Esteban JI, Rice CM, Gómez J, Gastaminza P, Domingo E, Perales C.

J Virol. 2017 Apr 28;91(10). pii: e02505-16. doi: 10.1128/JVI.02505-16. Print 2017 May 15.

6.

Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture.

Sepúlveda-Crespo D, Jiménez JL, Gómez R, De La Mata FJ, Majano PL, Muñoz-Fernández MÁ, Gastaminza P.

Nanomedicine. 2017 Jan;13(1):49-58. doi: 10.1016/j.nano.2016.08.018. Epub 2016 Aug 22.

PMID:
27562210
7.

Structural Changes In Cells Imaged by Soft X-ray Cryo-Tomography During Hepatitis C Virus Infection.

Pérez-Berná AJ, Rodríguez MJ, Chichón FJ, Friesland MF, Sorrentino A, Carrascosa JL, Pereiro E, Gastaminza P.

ACS Nano. 2016 Jul 26;10(7):6597-611. doi: 10.1021/acsnano.6b01374. Epub 2016 Jun 28.

PMID:
27328170
8.

Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication.

Carnero E, Barriocanal M, Prior C, Pablo Unfried J, Segura V, Guruceaga E, Enguita M, Smerdou C, Gastaminza P, Fortes P.

EMBO Rep. 2016 Jul;17(7):1013-28. doi: 10.15252/embr.201541763. Epub 2016 Jun 9.

9.

Cellular stress responses in hepatitis C virus infection: Mastering a two-edged sword.

Vasallo C, Gastaminza P.

Virus Res. 2015 Nov 2;209:100-17. doi: 10.1016/j.virusres.2015.03.013. Epub 2015 Mar 30. Review.

PMID:
25836277
10.

Clathrin mediates infectious hepatitis C virus particle egress.

Benedicto I, Gondar V, Molina-Jiménez F, García-Buey L, López-Cabrera M, Gastaminza P, Majano PL.

J Virol. 2015 Apr;89(8):4180-90. doi: 10.1128/JVI.03620-14. Epub 2015 Jan 28.

11.

Selective inhibition of hepatitis C virus infection by hydroxyzine and benztropine.

Mingorance L, Friesland M, Coto-Llerena M, Pérez-del-Pulgar S, Boix L, López-Oliva JM, Bruix J, Forns X, Gastaminza P.

Antimicrob Agents Chemother. 2014 Jun;58(6):3451-60. doi: 10.1128/AAC.02619-14. Epub 2014 Apr 7.

12.

[Meeting Report: 20 years after the First International Symposium on hepatitis C virus and related viruses].

Carnero E, Díez J, Fortes P, Gastaminza P, Majano P, Martínez MA, Pérez-del-Pulgar S, Quer J, López-Labrador FX; Grupo de Estudio de Hepatitis Víricas de la Sociedad Española de Virología.

Gastroenterol Hepatol. 2013 Dec;36(10):641-6. doi: 10.1016/j.gastrohep.2013.06.001. Epub 2013 Sep 5. Spanish.

PMID:
24011709
13.

Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes.

Larrea E, Riezu-Boj JI, Aldabe R, Guembe L, Echeverria I, Balasiddaiah A, Gastaminza P, Civeira MP, Sarobe P, Prieto J.

Gut. 2014 Apr;63(4):665-73. doi: 10.1136/gutjnl-2012-304377. Epub 2013 Jun 20.

PMID:
23787026
14.

Sigma-1 receptor regulates early steps of viral RNA replication at the onset of hepatitis C virus infection.

Friesland M, Mingorance L, Chung J, Chisari FV, Gastaminza P.

J Virol. 2013 Jun;87(11):6377-90. doi: 10.1128/JVI.03557-12. Epub 2013 Mar 27.

15.

A summary of the 18th International Symposium on Hepatitis C Virus and Related Viruses.

Polyak SJ, Morishima C, Scott JD, Gastaminza P, Cox A, de Araújo ES, Higgs MR, Loo YM, Golden-Mason L, Lindenbach BD, Baumert TF, Randall G, Gale M Jr.

Gastroenterology. 2012 Jan;142(1):e1-5. doi: 10.1053/j.gastro.2011.11.002. No abstract available. Erratum in: Gastroenterology. 2012 Feb;142(2):411. Gastaminza, Pablo [added].

PMID:
22185796
16.

Self-assembling peptide nanotubes with antiviral activity against hepatitis C virus.

Montero A, Gastaminza P, Law M, Cheng G, Chisari FV, Ghadiri MR.

Chem Biol. 2011 Nov 23;18(11):1453-62. doi: 10.1016/j.chembiol.2011.08.017.

17.

Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection.

Gastaminza P, Pitram SM, Dreux M, Krasnova LB, Whitten-Bauer C, Dong J, Chung J, Fokin VV, Sharpless KB, Chisari FV.

J Virol. 2011 Jun;85(11):5513-23. doi: 10.1128/JVI.02116-10. Epub 2011 Mar 23.

18.

Ultrastructural and biophysical characterization of hepatitis C virus particles produced in cell culture.

Gastaminza P, Dryden KA, Boyd B, Wood MR, Law M, Yeager M, Chisari FV.

J Virol. 2010 Nov;84(21):10999-1009. doi: 10.1128/JVI.00526-10. Epub 2010 Aug 4.

19.

Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection.

Takahashi K, Asabe S, Wieland S, Garaigorta U, Gastaminza P, Isogawa M, Chisari FV.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7431-6. doi: 10.1073/pnas.1002301107. Epub 2010 Mar 15.

20.

Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection.

Gastaminza P, Whitten-Bauer C, Chisari FV.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):291-6. doi: 10.1073/pnas.0912966107. Epub 2009 Dec 7.

21.

The autophagy machinery is required to initiate hepatitis C virus replication.

Dreux M, Gastaminza P, Wieland SF, Chisari FV.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14046-51. doi: 10.1073/pnas.0907344106. Epub 2009 Aug 3.

22.

Analysis of the interaction of influenza virus polymerase complex with human cell factors.

Jorba N, Juarez S, Torreira E, Gastaminza P, Zamarreño N, Albar JP, Ortín J.

Proteomics. 2008 May;8(10):2077-88. doi: 10.1002/pmic.200700508.

PMID:
18491320
23.

A virocidal amphipathic {alpha}-helical peptide that inhibits hepatitis C virus infection in vitro.

Cheng G, Montero A, Gastaminza P, Whitten-Bauer C, Wieland SF, Isogawa M, Fredericksen B, Selvarajah S, Gallay PA, Ghadiri MR, Chisari FV.

Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3088-93. doi: 10.1073/pnas.0712380105. Epub 2008 Feb 19.

24.

Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion.

Gastaminza P, Cheng G, Wieland S, Zhong J, Liao W, Chisari FV.

J Virol. 2008 Mar;82(5):2120-9. Epub 2007 Dec 12.

25.

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge.

Law M, Maruyama T, Lewis J, Giang E, Tarr AW, Stamataki Z, Gastaminza P, Chisari FV, Jones IM, Fox RI, Ball JK, McKeating JA, Kneteman NM, Burton DR.

Nat Med. 2008 Jan;14(1):25-7. Epub 2007 Dec 6.

PMID:
18064037
26.

Differential biophysical properties of infectious intracellular and secreted hepatitis C virus particles.

Gastaminza P, Kapadia SB, Chisari FV.

J Virol. 2006 Nov;80(22):11074-81. Epub 2006 Sep 6.

27.

Persistent hepatitis C virus infection in vitro: coevolution of virus and host.

Zhong J, Gastaminza P, Chung J, Stamataki Z, Isogawa M, Cheng G, McKeating JA, Chisari FV.

J Virol. 2006 Nov;80(22):11082-93. Epub 2006 Sep 6.

28.

Robust hepatitis C virus infection in vitro.

Zhong J, Gastaminza P, Cheng G, Kapadia S, Kato T, Burton DR, Wieland SF, Uprichard SL, Wakita T, Chisari FV.

Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9294-9. Epub 2005 Jun 6.

29.

3D structure of the influenza virus polymerase complex: localization of subunit domains.

Area E, Martín-Benito J, Gastaminza P, Torreira E, Valpuesta JM, Carrascosa JL, Ortín J.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):308-13. Epub 2003 Dec 22.

30.
31.

The replication activity of influenza virus polymerase is linked to the capacity of the PA subunit to induce proteolysis.

Perales B, Sanz-Ezquerro JJ, Gastaminza P, Ortega J, Santarén JF, Ortín J, Nieto A.

J Virol. 2000 Feb;74(3):1307-12.

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