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Items: 1 to 50 of 231

1.

Exenatide regulates pancreatic islet integrity and insulin sensitivity in baboons.

Fiorentino TV, Casiraghi F, Davalli AM, Finzi G, La Rosa S, Higgins PB, Abrahamian GA, Marando A, Sessa F, Perego C, Guardado-Mendoza R, Kamath S, Ricotti A, Fiorina P, Daniele G, Paez AM, Andreozzi F, Bastarrachea RA, Comuzzie AG, Gastaldelli A, Chavez AO, Di Cairano ES, Frost PA, Luzi L, Dick EJ Jr, Halff GA, DeFronzo RA, Folli F.

JCI Insight. 2019 Sep 19. pii: 93091. doi: 10.1172/jci.insight.93091. [Epub ahead of print]

2.

Association of serum lipids with β-cell function in obese children and adolescents.

Bedogni G, Mari A, De Col A, Tamini S, Gastaldelli A, Sartorio A.

Endocr Connect. 2019 Sep 1. pii: EC-19-0333.R1. doi: 10.1530/EC-19-0333. [Epub ahead of print]

3.

Mechanism of Action of Inhaled Insulin on Whole Body Glucose Metabolism in Subjects with Type 2 Diabetes Mellitus.

Mehta RJ, Gastaldelli A, Balas B, Ricotti A, DeFronzo RA, Tripathy D.

Int J Mol Sci. 2019 Aug 29;20(17). pii: E4230. doi: 10.3390/ijms20174230.

4.

The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake.

Jensen CH, Kosmina R, Rydén M, Baun C, Hvidsten S, Andersen MS, Christensen LL, Gastaldelli A, Marraccini P, Arner P, Jørgensen CD, Laborda J, Holst JJ, Andersen DC.

EBioMedicine. 2019 Aug;46:368-380. doi: 10.1016/j.ebiom.2019.07.070. Epub 2019 Aug 3.

5.

Crosstalk between adipose tissue insulin resistance and liver macrophages in non-alcoholic fatty liver disease.

Rosso C, Kazankov K, Younes R, Esmaili S, Marietti M, Sacco M, Carli F, Gaggini M, Salomone F, Møller HJ, Abate ML, Vilstrup H, Gastaldelli A, George J, Grønbæk H, Bugianesi E.

J Hepatol. 2019 Jul 10. pii: S0168-8278(19)30404-0. doi: 10.1016/j.jhep.2019.06.031. [Epub ahead of print]

PMID:
31301321
6.

Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis.

Hackl MT, Fürnsinn C, Schuh CM, Krssak M, Carli F, Guerra S, Freudenthaler A, Baumgartner-Parzer S, Helbich TH, Luger A, Zeyda M, Gastaldelli A, Buettner C, Scherer T.

Nat Commun. 2019 Jun 20;10(1):2717. doi: 10.1038/s41467-019-10684-1.

7.

Bile acid changes after metabolic surgery are linked to improvement in insulin sensitivity.

Ahlin S, Cefalù C, Bondia-Pons I, Capristo E, Marini L, Gastaldelli A, Mingrone G, Nolan JJ.

Br J Surg. 2019 Aug;106(9):1178-1186. doi: 10.1002/bjs.11208. Epub 2019 Jun 19.

PMID:
31216062
8.

Cardiometabolic risk and subclinical vascular damage assessment in idiopathic inflammatory myopathies: a challenge for the clinician.

Barsotti S, Saponaro C, Gaggini M, Talarico R, Bianchini E, Di Lascio N, Ferrari C, Buzzigoli E, Mosca M, Gastaldelli A, Neri R, Morales MA.

Clin Exp Rheumatol. 2019 Mar 18. [Epub ahead of print]

PMID:
30943137
9.

Women-specific predictors of cardiovascular disease risk - new paradigms.

Maffei S, Guiducci L, Cugusi L, Cadeddu C, Deidda M, Gallina S, Sciomer S, Gastaldelli A, Kaski JC; Working Group on "Gender difference in cardiovascular disease" of the Italian Society of Cardiology.

Int J Cardiol. 2019 Jul 1;286:190-197. doi: 10.1016/j.ijcard.2019.02.005. Epub 2019 Feb 15.

PMID:
30803890
10.

Role of vagal activation in postprandial glucose metabolism after gastric bypass in individuals with and without hypoglycaemia.

Salehi M, Gastaldelli A, D'Alessio DA.

Diabetes Obes Metab. 2019 Jun;21(6):1513-1517. doi: 10.1111/dom.13676. Epub 2019 Mar 27.

PMID:
30785669
11.

Beta-cell sensitivity to insulinotropic gut hormones is reduced after gastric bypass surgery.

Salehi M, Gastaldelli A, D'Alessio DA.

Gut. 2019 Oct;68(10):1838-1845. doi: 10.1136/gutjnl-2018-317760. Epub 2019 Feb 16.

PMID:
30772836
12.

Effects of intravenous AICAR (5-aminoimidazole-4-carboximide riboside) administration on insulin signaling and resistance in premature baboons, Papio sp.

Blanco CL, Gastaldelli A, Anzueto DG, Winter LA, Seidner SR, McCurnin DC, Liang H, Javors MA, DeFronzo RA, Musi N.

PLoS One. 2018 Dec 12;13(12):e0208757. doi: 10.1371/journal.pone.0208757. eCollection 2018.

13.

Prevalence of and risk factors for fatty liver in the general population of Northern Italy: the Bagnacavallo Study.

Foschi FG, Bedogni G, Domenicali M, Giacomoni P, Dall'Aglio AC, Dazzani F, Lanzi A, Conti F, Savini S, Saini G, Bernardi M, Andreone P, Gastaldelli A, Casadei Gardini A, Tiribelli C, Bellentani S, Stefanini GF.

BMC Gastroenterol. 2018 Nov 28;18(1):177. doi: 10.1186/s12876-018-0906-8.

14.

Phthalates Exposure as Determinant of Albuminuria in Subjects With Type 2 Diabetes: A Cross-Sectional Study.

Mengozzi A, Carli F, Biancalana E, Della Latta V, Seghieri M, Gastaldelli A, Solini A.

J Clin Endocrinol Metab. 2019 May 1;104(5):1491-1499. doi: 10.1210/jc.2018-01797.

PMID:
30462244
15.

Interaction of GLP-1 and Ghrelin on Glucose Tolerance in Healthy Humans.

Page LC, Gastaldelli A, Gray SM, D'Alessio DA, Tong J.

Diabetes. 2018 Oct;67(10):1976-1985. doi: 10.2337/db18-0451. Epub 2018 Jul 31.

16.

The LIFE PERSUADED project approach on phthalates and bisphenol A biomonitoring in Italian mother-child pairs linking exposure and juvenile diseases.

La Rocca C, Maranghi F, Tait S, Tassinari R, Baldi F, Bottaro G, Buzzigoli E, Carli F, Cianfarani S, Conte R, Deodati A, Gastaldelli A, Pala AP, Raffaelli A, Saponaro C, Scirè G, Spadoni GL, Busani L; LIFE PERSUADED Project Group.

Environ Sci Pollut Res Int. 2018 Sep;25(25):25618-25625. doi: 10.1007/s11356-018-2660-4. Epub 2018 Jul 4.

17.

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars.

Luukkonen PK, Sädevirta S, Zhou Y, Kayser B, Ali A, Ahonen L, Lallukka S, Pelloux V, Gaggini M, Jian C, Hakkarainen A, Lundbom N, Gylling H, Salonen A, Orešič M, Hyötyläinen T, Orho-Melander M, Rissanen A, Gastaldelli A, Clément K, Hodson L, Yki-Järvinen H.

Diabetes Care. 2018 Aug;41(8):1732-1739. doi: 10.2337/dc18-0071. Epub 2018 May 29.

PMID:
29844096
18.

Publisher Correction: Muscle and adipose tissue morphology, insulin sensitivity and beta-cell function in diabetic and nondiabetic obese patients: effects of bariatric surgery.

Camastra S, Vitali A, Anselmino M, Gastaldelli A, Bellini R, Berta R, Severi I, Baldi S, Astiarraga B, Barbatelli G, Cinti S, Ferrannini E.

Sci Rep. 2018 May 22;8(1):8177. doi: 10.1038/s41598-018-25221-1.

19.

Older Subjects With β-Cell Dysfunction Have an Accentuated Incretin Release.

de Jesús Garduno-Garcia J, Gastaldelli A, DeFronzo RA, Lertwattanarak R, Holst JJ, Musi N.

J Clin Endocrinol Metab. 2018 Jul 1;103(7):2613-2619. doi: 10.1210/jc.2018-00260.

20.

Vitamin D Supplementation in Patients With Type 2 Diabetes: The Vitamin D for Established Type 2 Diabetes (DDM2) Study.

Angellotti E, D'Alessio D, Dawson-Hughes B, Nelson J, Cohen RM, Gastaldelli A, Pittas AG.

J Endocr Soc. 2018 Feb 26;2(4):310-321. doi: 10.1210/js.2018-00015. eCollection 2018 Apr 1.

21.

Digital liver biopsy: Bio-imaging of fatty liver for translational and clinical research.

Mancini M, Summers P, Faita F, Brunetto MR, Callea F, De Nicola A, Di Lascio N, Farinati F, Gastaldelli A, Gridelli B, Mirabelli P, Neri E, Salvadori PA, Rebelos E, Tiribelli C, Valenti L, Salvatore M, Bonino F.

World J Hepatol. 2018 Feb 27;10(2):231-245. doi: 10.4254/wjh.v10.i2.231. Review.

22.

The antidepressant fluoxetine acts on energy balance and leptin sensitivity via BDNF.

Scabia G, Barone I, Mainardi M, Ceccarini G, Scali M, Buzzigoli E, Dattilo A, Vitti P, Gastaldelli A, Santini F, Pizzorusso T, Maffei L, Maffei M.

Sci Rep. 2018 Jan 29;8(1):1781. doi: 10.1038/s41598-018-19886-x.

23.

Author Correction: Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD.

Pierantonelli I, Rychlicki C, Agostinelli L, Giordano DM, Gaggini M, Fraumene C, Saponaro C, Manghina V, Sartini L, Mingarelli E, Pinto C, Buzzigoli E, Trozzi L, Giordano A, Marzioni M, De Minicis S, Uzzau S, Cinti S, Gastaldelli A, Svegliati-Baroni G.

Sci Rep. 2017 Dec 11;7(1):17568. doi: 10.1038/s41598-017-17187-3.

24.

Reply.

Gaggini M, Bugianesi E, Gastaldelli A.

Hepatology. 2018 Mar;67(3):1178-1180. doi: 10.1002/hep.29699. Epub 2018 Jan 30. No abstract available.

25.

Beta-cell sensitivity to glucose is impaired after gastric bypass surgery.

Salehi M, Gastaldelli A, D'Alessio DA.

Diabetes Obes Metab. 2018 Apr;20(4):872-878. doi: 10.1111/dom.13165. Epub 2017 Dec 18.

26.

Insulin resistance and reduced metabolic flexibility: cause or consequence of NAFLD?

Gastaldelli A.

Clin Sci (Lond). 2017 Nov 6;131(22):2701-2704. doi: 10.1042/CS20170987. Print 2017 Nov 15.

PMID:
29109303
27.

The color of fat and its central role in the development and progression of metabolic diseases.

Gaggini M, Carli F, Gastaldelli A.

Horm Mol Biol Clin Investig. 2017 Sep 25;31(1). pii: /j/hmbci.2017.31.issue-1/hmbci-2017-0060/hmbci-2017-0060.xml. doi: 10.1515/hmbci-2017-0060. Review.

PMID:
28942436
28.

Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD.

Pierantonelli I, Rychlicki C, Agostinelli L, Giordano DM, Gaggini M, Fraumene C, Saponaro C, Manghina V, Sartini L, Mingarelli E, Pinto C, Buzzigoli E, Trozzi L, Giordano A, Marzioni M, Minicis S, Uzzau S, Cinti S, Gastaldelli A, Svegliati-Baroni G.

Sci Rep. 2017 Sep 22;7(1):12200. doi: 10.1038/s41598-017-11744-6. Erratum in: Sci Rep. 2017 Dec 11;7(1):17568.

29.

Pioglitazone Improves Left Ventricular Diastolic Function in Subjects With Diabetes.

Clarke GD, Solis-Herrera C, Molina-Wilkins M, Martinez S, Merovci A, Cersosimo E, Chilton RJ, Iozzo P, Gastaldelli A, Abdul-Ghani M, DeFronzo RA.

Diabetes Care. 2017 Nov;40(11):1530-1536. doi: 10.2337/dc17-0078. Epub 2017 Aug 28.

30.

Muscle and adipose tissue morphology, insulin sensitivity and beta-cell function in diabetic and nondiabetic obese patients: effects of bariatric surgery.

Camastra S, Vitali A, Anselmino M, Gastaldelli A, Bellini R, Berta R, Severi I, Baldi S, Astiarraga B, Barbatelli G, Cinti S, Ferrannini E.

Sci Rep. 2017 Aug 21;7(1):9007. doi: 10.1038/s41598-017-08444-6. Erratum in: Sci Rep. 2018 May 22;8(1):8177.

31.

Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance.

Gaggini M, Carli F, Rosso C, Buzzigoli E, Marietti M, Della Latta V, Ciociaro D, Abate ML, Gambino R, Cassader M, Bugianesi E, Gastaldelli A.

Hepatology. 2018 Jan;67(1):145-158. doi: 10.1002/hep.29465. Epub 2017 Nov 17.

PMID:
28802074
32.

Osteopontin in hepatocellular carcinoma: A possible biomarker for diagnosis and follow-up.

Cabiati M, Gaggini M, Cesare MM, Caselli C, De Simone P, Filipponi F, Basta G, Gastaldelli A, Del Ry S.

Cytokine. 2017 Nov;99:59-65. doi: 10.1016/j.cyto.2017.07.004. Epub 2017 Jul 12.

PMID:
28711012
33.

Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study.

Isokuortti E, Zhou Y, Peltonen M, Bugianesi E, Clement K, Bonnefont-Rousselot D, Lacorte JM, Gastaldelli A, Schuppan D, Schattenberg JM, Hakkarainen A, Lundbom N, Jousilahti P, Männistö S, Keinänen-Kiukaanniemi S, Saltevo J, Anstee QM, Yki-Järvinen H.

Diabetologia. 2017 Oct;60(10):1873-1882. doi: 10.1007/s00125-017-4340-1. Epub 2017 Jun 29.

PMID:
28660493
34.

Glucose kinetics: an update and novel insights into its regulation by glucagon and GLP-1.

Gastaldelli A, Gaggini M, DeFronzo R.

Curr Opin Clin Nutr Metab Care. 2017 Jul;20(4):300-309. doi: 10.1097/MCO.0000000000000384. Review.

PMID:
28463898
35.

Response to Comment on Gastaldelli et al. Short-term Effects of Laparoscopic Adjustable Gastric Banding Versus Roux-en-Y Gastric Bypass. Diabetes Care 2016;39:1925-1931.

Gastaldelli A, Rubino F, Mingrone G.

Diabetes Care. 2017 Apr;40(4):e50. doi: 10.2337/dci16-0050. No abstract available.

PMID:
28325806
36.

Hepatic Insulin Resistance and Altered Gluconeogenic Pathway in Premature Baboons.

McGill-Vargas L, Gastaldelli A, Liang H, Anzueto Guerra D, Johnson-Pais T, Seidner S, McCurnin D, Muscogiuri G, DeFronzo R, Musi N, Blanco C.

Endocrinology. 2017 May 1;158(5):1140-1151. doi: 10.1210/en.2016-1806.

37.

Chronic Intranasal Insulin Does Not Affect Hepatic Lipids but Lowers Circulating BCAAs in Healthy Male Subjects.

Scherer T, Wolf P, Smajis S, Gaggini M, Hackl M, Gastaldelli A, Klimek P, Einwallner E, Marculescu R, Luger A, Fürnsinn C, Trattnig S, Buettner C, Krššák M, Krebs M.

J Clin Endocrinol Metab. 2017 Apr 1;102(4):1325-1332. doi: 10.1210/jc.2016-3623.

38.

An extended fatty liver index to predict non-alcoholic fatty liver disease.

Kantartzis K, Rettig I, Staiger H, Machann J, Schick F, Scheja L, Gastaldelli A, Bugianesi E, Peter A, Schulze MB, Fritsche A, Häring HU, Stefan N.

Diabetes Metab. 2017 Jun;43(3):229-239. doi: 10.1016/j.diabet.2016.11.006. Epub 2017 Jan 12.

39.

Role of Adipose Tissue Insulin Resistance in the Natural History of Type 2 Diabetes: Results From the San Antonio Metabolism Study.

Gastaldelli A, Gaggini M, DeFronzo RA.

Diabetes. 2017 Apr;66(4):815-822. doi: 10.2337/db16-1167. Epub 2017 Jan 4.

40.

Increased FNDC5/Irisin expression in human hepatocellular carcinoma.

Gaggini M, Cabiati M, Del Turco S, Navarra T, De Simone P, Filipponi F, Del Ry S, Gastaldelli A, Basta G.

Peptides. 2017 Feb;88:62-66. doi: 10.1016/j.peptides.2016.12.014. Epub 2016 Dec 21.

PMID:
28012856
41.

Response to: Drug therapy for ectopic fat: myth or reality?

Gastaldelli A, Gaggini M.

Expert Rev Cardiovasc Ther. 2017 Feb;15(2):73-74. doi: 10.1080/14779072.2017.1274234. Epub 2016 Dec 26. No abstract available.

PMID:
28002972
42.

Gamma-glutamyltransferase, fatty liver index and hepatic insulin resistance are associated with incident hypertension in two longitudinal studies.

Bonnet F, Gastaldelli A, Pihan-Le Bars F, Natali A, Roussel R, Petrie J, Tichet J, Marre M, Fromenty B, Balkau B; D.E.S.I.R., RISC Study Groups.

J Hypertens. 2017 Mar;35(3):493-500. doi: 10.1097/HJH.0000000000001204.

PMID:
27984413
43.

Pathophysiology of Non Alcoholic Fatty Liver Disease.

Petta S, Gastaldelli A, Rebelos E, Bugianesi E, Messa P, Miele L, Svegliati-Baroni G, Valenti L, Bonino F.

Int J Mol Sci. 2016 Dec 11;17(12). pii: E2082. Review.

44.

Effect of exenatide on postprandial glucose fluxes, lipolysis, and ß-cell function in non-diabetic, morbidly obese patients.

Camastra S, Astiarraga B, Tura A, Frascerra S, Ciociaro D, Mari A, Gastaldelli A, Ferrannini E.

Diabetes Obes Metab. 2017 Mar;19(3):412-420. doi: 10.1111/dom.12836. Epub 2017 Jan 10.

PMID:
27898183
45.

Novel hepato-preferential basal insulin peglispro (BIL) does not differentially affect insulin sensitivity compared with insulin glargine in patients with type 1 and type 2 diabetes.

Porksen N, Linnebjerg H, Garhyan P, Lam EC, Knadler MP, Jacober SJ, Hoevelmann U, Plum-Moerschel L, Watkins E, Gastaldelli A, Heise T.

Diabetes Obes Metab. 2017 Apr;19(4):482-488. doi: 10.1111/dom.12834. Epub 2017 Feb 7.

PMID:
27888561
46.

Glucagon-like Peptide-1 and the Central/Peripheral Nervous System: Crosstalk in Diabetes.

Muscogiuri G, DeFronzo RA, Gastaldelli A, Holst JJ.

Trends Endocrinol Metab. 2017 Feb;28(2):88-103. doi: 10.1016/j.tem.2016.10.001. Epub 2016 Oct 27. Review.

PMID:
27871675
47.

Ectopic fat: a target for cardiometabolic risk management.

Gastaldelli A, Gaggini M.

Expert Rev Cardiovasc Ther. 2016 Dec;14(12):1301-1303. Epub 2016 Nov 18. No abstract available.

PMID:
27817220
48.

Exenatide improves both hepatic and adipose tissue insulin resistance: A dynamic positron emission tomography study.

Gastaldelli A, Gaggini M, Daniele G, Ciociaro D, Cersosimo E, Tripathy D, Triplitt C, Fox P, Musi N, DeFronzo R, Iozzo P.

Hepatology. 2016 Dec;64(6):2028-2037. doi: 10.1002/hep.28827.

PMID:
27639082
49.

Short-term Effects of Laparoscopic Adjustable Gastric Banding Versus Roux-en-Y Gastric Bypass.

Gastaldelli A, Iaconelli A, Gaggini M, Magnone MC, Veneziani A, Rubino F, Mingrone G.

Diabetes Care. 2016 Nov;39(11):1925-1931. Epub 2016 Aug 29.

PMID:
27573937
50.

Glucose uptake saturation explains glucose kinetics profiles measured by different tests.

Bizzotto R, Natali A, Gastaldelli A, Muscelli E, Krssak M, Brehm A, Roden M, Ferrannini E, Mari A.

Am J Physiol Endocrinol Metab. 2016 Aug 1;311(2):E346-57. doi: 10.1152/ajpendo.00045.2016. Epub 2016 May 31.

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