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Items: 1 to 50 of 323

1.

The study of protein recruitment to UV-induced DNA lesions can be distorted by photoconversion of DNA dyes like Hoechst or DAPI.

Hurst V, Gasser SM.

F1000Res. 2019 Jan 25;8:104. doi: 10.12688/f1000research.17865.1. eCollection 2019.

2.

General practitioners' willingness to participate in research: A survey in central Switzerland.

Tawo S, Gasser S, Gemperli A, Merlo C, Essig S.

PLoS One. 2019 Mar 1;14(3):e0213358. doi: 10.1371/journal.pone.0213358. eCollection 2019.

3.

Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression.

Padeken J, Zeller P, Towbin B, Katic I, Kalck V, Methot SP, Gasser SM.

Genes Dev. 2019 Feb 25. doi: 10.1101/gad.322495.118. [Epub ahead of print]

4.

Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65.

Delaney CE, Methot SP, Guidi M, Katic I, Gasser SM, Padeken J.

J Cell Biol. 2019 Mar 4;218(3):820-838. doi: 10.1083/jcb.201811038. Epub 2019 Feb 8.

PMID:
30737265
5.

Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways.

Klein HL, Bačinskaja G, Che J, Cheblal A, Elango R, Epshtein A, Fitzgerald DM, Gómez-González B, Khan SR, Kumar S, Leland BA, Marie L, Mei Q, Miné-Hattab J, Piotrowska A, Polleys EJ, Putnam CD, Radchenko EA, Saada AA, Sakofsky CJ, Shim EY, Stracy M, Xia J, Yan Z, Yin Y, Aguilera A, Argueso JL, Freudenreich CH, Gasser SM, Gordenin DA, Haber JE, Ira G, Jinks-Robertson S, King MC, Kolodner RD, Kuzminov A, Lambert SA, Lee SE, Miller KM, Mirkin SM, Petes TD, Rosenberg SM, Rothstein R, Symington LS, Zawadzki P, Kim N, Lisby M, Malkova A.

Microb Cell. 2019 Jan 7;6(1):1-64. doi: 10.15698/mic2019.01.664. Review.

6.

Meiosis-specific prophase-like pathway controls cleavage-independent release of cohesin by Wapl phosphorylation.

Challa K, Fajish V G, Shinohara M, Klein F, Gasser SM, Shinohara A.

PLoS Genet. 2019 Jan 3;15(1):e1007851. doi: 10.1371/journal.pgen.1007851. eCollection 2019 Jan.

7.

Challenges and guidelines toward 4D nucleome data and model standards.

Marti-Renom MA, Almouzni G, Bickmore WA, Bystricky K, Cavalli G, Fraser P, Gasser SM, Giorgetti L, Heard E, Nicodemi M, Nollmann M, Orozco M, Pombo A, Torres-Padilla ME.

Nat Genet. 2018 Oct;50(10):1352-1358. doi: 10.1038/s41588-018-0236-3. Epub 2018 Sep 27. Review.

PMID:
30262815
8.

Chromosome Dynamics in Response to DNA Damage.

Seeber A, Hauer MH, Gasser SM.

Annu Rev Genet. 2018 Nov 23;52:295-319. doi: 10.1146/annurev-genet-120417-031334. Epub 2018 Sep 12.

PMID:
30208290
9.

Asymmetric Processing of DNA Ends at a Double-Strand Break Leads to Unconstrained Dynamics and Ectopic Translocation.

Marcomini I, Shimada K, Delgoshaie N, Yamamoto I, Seeber A, Cheblal A, Horigome C, Naumann U, Gasser SM.

Cell Rep. 2018 Sep 4;24(10):2614-2628.e4. doi: 10.1016/j.celrep.2018.07.102.

10.

Fatale immunmediierte organisierende Pneumonie unter Pembrolizumab – Therapie eines pulmonalen Adenokarzinoms.

Gasser S, Krenbek D, Hochmair M.

Rofo. 2018 Dec;190(12):1161-1163. doi: 10.1055/a-0640-3290. Epub 2018 Sep 4. German. No abstract available.

PMID:
30180263
11.

A memetic optimization algorithm for multi-constrained multicast routing in ad hoc networks.

Ramadan RM, Gasser SM, El-Mahallawy MS, Hammad K, El Bakly AM.

PLoS One. 2018 Mar 6;13(3):e0193142. doi: 10.1371/journal.pone.0193142. eCollection 2018.

12.

Genomic analysis in patients with myxomatous mitral valve prolapse: current state of knowledge.

Gasser S, Reichenspurner H, Girdauskas E.

BMC Cardiovasc Disord. 2018 Feb 27;18(1):41. doi: 10.1186/s12872-018-0755-y.

13.

Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function.

Ahringer J, Gasser SM.

Genetics. 2018 Feb;208(2):491-511. doi: 10.1534/genetics.117.300386. Review.

14.

Chromatin and nucleosome dynamics in DNA damage and repair.

Hauer MH, Gasser SM.

Genes Dev. 2017 Nov 15;31(22):2204-2221. doi: 10.1101/gad.307702.117. Review.

15.

The Importance of Satellite Sequence Repression for Genome Stability.

Zeller P, Gasser SM.

Cold Spring Harb Symp Quant Biol. 2017;82:15-24. doi: 10.1101/sqb.2017.82.033662. Epub 2017 Nov 13.

PMID:
29133300
16.

Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.

Deshpande I, Seeber A, Shimada K, Keusch JJ, Gut H, Gasser SM.

Mol Cell. 2017 Oct 19;68(2):431-445.e5. doi: 10.1016/j.molcel.2017.09.019. Epub 2017 Oct 12.

17.

The INO80 remodeller in transcription, replication and repair.

Poli J, Gasser SM, Papamichos-Chronakis M.

Philos Trans R Soc Lond B Biol Sci. 2017 Oct 5;372(1731). pii: 20160290. doi: 10.1098/rstb.2016.0290. Review.

18.

Chromatin modifiers and remodellers in DNA repair and signalling.

Jeggo PA, Downs JA, Gasser SM.

Philos Trans R Soc Lond B Biol Sci. 2017 Oct 5;372(1731). pii: 20160279. doi: 10.1098/rstb.2016.0279. No abstract available.

19.

The role of the tumour microenvironment in immunotherapy.

Gasser S, Lim LHK, Cheung FSG.

Endocr Relat Cancer. 2017 Dec;24(12):T283-T295. doi: 10.1530/ERC-17-0146. Epub 2017 Jul 28. Review.

PMID:
28754821
20.

A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage.

Shimada K, Gasser SM.

J Cell Biol. 2017 Mar 6;216(3):535-537. doi: 10.1083/jcb.201701038. Epub 2017 Feb 24.

21.

Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories.

Amitai A, Seeber A, Gasser SM, Holcman D.

Cell Rep. 2017 Jan 31;18(5):1200-1214. doi: 10.1016/j.celrep.2017.01.018.

22.

Selfish DNA and Epigenetic Repression Revisited.

Gasser SM.

Genetics. 2016 Nov;204(3):837-839. doi: 10.1534/genetics.116.196287. No abstract available.

23.

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates.

Hauer MH, Seeber A, Singh V, Thierry R, Sack R, Amitai A, Kryzhanovska M, Eglinger J, Holcman D, Owen-Hughes T, Gasser SM.

Nat Struct Mol Biol. 2017 Feb;24(2):99-107. doi: 10.1038/nsmb.3347. Epub 2017 Jan 9.

PMID:
28067915
24.

RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together.

Seeber A, Hegnauer AM, Hustedt N, Deshpande I, Poli J, Eglinger J, Pasero P, Gut H, Shinohara M, Hopfner KP, Shimada K, Gasser SM.

Mol Cell. 2016 Dec 1;64(5):951-966. doi: 10.1016/j.molcel.2016.10.032. Epub 2016 Nov 23.

25.

Chromatin organization and dynamics in double-strand break repair.

Seeber A, Gasser SM.

Curr Opin Genet Dev. 2017 Apr;43:9-16. doi: 10.1016/j.gde.2016.10.005. Epub 2016 Oct 31. Review.

26.

Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability.

Zeller P, Padeken J, van Schendel R, Kalck V, Tijsterman M, Gasser SM.

Nat Genet. 2016 Nov;48(11):1385-1395. doi: 10.1038/ng.3672. Epub 2016 Sep 26.

PMID:
27668659
27.

Mechanism of chromatin segregation to the nuclear periphery in C. elegans embryos.

Gonzalez-Sandoval A, Gasser SM.

Worm. 2016 May 31;5(3):e1190900. eCollection 2016.

28.

Sensing of dangerous DNA.

Gasser S, Zhang WYL, Tan NYJ, Tripathi S, Suter MA, Chew ZH, Khatoo M, Ngeow J, Cheung FSG.

Mech Ageing Dev. 2017 Jul;165(Pt A):33-46. doi: 10.1016/j.mad.2016.09.001. Epub 2016 Sep 7. Review.

PMID:
27614000
29.

DAMP-Induced Allograft and Tumor Rejection: The Circle Is Closing.

Land WG, Agostinis P, Gasser S, Garg AD, Linkermann A.

Am J Transplant. 2016 Dec;16(12):3322-3337. doi: 10.1111/ajt.14012. Epub 2016 Sep 21. Review.

30.

SUMO wrestles breaks to the nuclear ring's edge.

Horigome C, Gasser SM.

Cell Cycle. 2016 Nov 16;15(22):3011-3013. Epub 2016 Aug 2. No abstract available.

31.

CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells.

Sauer M, Schuldner M, Hoffmann N, Cetintas A, Reiners KS, Shatnyeva O, Hallek M, Hansen HP, Gasser S, von Strandmann EP.

Oncogene. 2017 Feb 16;36(7):933-941. doi: 10.1038/onc.2016.259. Epub 2016 Aug 1.

32.

Transplantation and Damage-Associated Molecular Patterns (DAMPs).

Land WG, Agostinis P, Gasser S, Garg AD, Linkermann A.

Am J Transplant. 2016 Dec;16(12):3338-3361. doi: 10.1111/ajt.13963. Epub 2016 Aug 24. Review.

33.

On TADs and LADs: Spatial Control Over Gene Expression.

Gonzalez-Sandoval A, Gasser SM.

Trends Genet. 2016 Aug;32(8):485-495. doi: 10.1016/j.tig.2016.05.004. Epub 2016 Jun 13. Review.

PMID:
27312344
34.

Spatial segregation of heterochromatin: Uncovering functionality in a multicellular organism.

Cabianca DS, Gasser SM.

Nucleus. 2016 May 3;7(3):301-7. doi: 10.1080/19491034.2016.1187354. Review.

35.

The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells.

Ho SS, Zhang WY, Tan NY, Khatoo M, Suter MA, Tripathi S, Cheung FS, Lim WK, Tan PH, Ngeow J, Gasser S.

Immunity. 2016 May 17;44(5):1177-89. doi: 10.1016/j.immuni.2016.04.010. Epub 2016 May 10.

36.

Nuclear Architecture: Past and Future Tense.

Gasser SM.

Trends Cell Biol. 2016 Jul;26(7):473-475. doi: 10.1016/j.tcb.2016.04.011. Epub 2016 May 10.

PMID:
27177990
37.

PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL.

Horigome C, Bustard DE, Marcomini I, Delgoshaie N, Tsai-Pflugfelder M, Cobb JA, Gasser SM.

Genes Dev. 2016 Apr 15;30(8):931-45. doi: 10.1101/gad.277665.116. Epub 2016 Apr 7.

38.

The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation.

Iwasaki D, Hayashihara K, Shima H, Higashide M, Terasawa M, Gasser SM, Shinohara M.

PLoS Genet. 2016 Mar 18;12(3):e1005942. doi: 10.1371/journal.pgen.1005942. eCollection 2016 Mar.

39.

Apoptotic Cells Release IL1 Receptor Antagonist in Response to Genotoxic Stress.

Chwee JY, Khatoo M, Tan NY, Gasser S.

Cancer Immunol Res. 2016 Apr;4(4):294-302. doi: 10.1158/2326-6066.CIR-15-0083. Epub 2016 Feb 12.

40.

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress.

Poli J, Gerhold CB, Tosi A, Hustedt N, Seeber A, Sack R, Herzog F, Pasero P, Shimada K, Hopfner KP, Gasser SM.

Genes Dev. 2016 Feb 1;30(3):337-54. doi: 10.1101/gad.273813.115. Epub 2016 Jan 21.

41.

Histones and histone modifications in perinuclear chromatin anchoring: from yeast to man.

Harr JC, Gonzalez-Sandoval A, Gasser SM.

EMBO Rep. 2016 Feb;17(2):139-55. doi: 10.15252/embr.201541809. Epub 2016 Jan 20. Review.

42.

Generating Primary Fibroblast Cultures from Mouse Ear and Tail Tissues.

Khan M, Gasser S.

J Vis Exp. 2016 Jan 10;(107). doi: 10.3791/53565.

43.

Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos.

Gonzalez-Sandoval A, Towbin BD, Kalck V, Cabianca DS, Gaidatzis D, Hauer MH, Geng L, Wang L, Yang T, Wang X, Zhao K, Gasser SM.

Cell. 2015 Dec 3;163(6):1333-47. doi: 10.1016/j.cell.2015.10.066. Epub 2015 Nov 19.

44.

Articular Cartilage Injury and Potential Remedies.

Chubinskaya S, Haudenschild D, Gasser S, Stannard J, Krettek C, Borrelli J Jr.

J Orthop Trauma. 2015 Dec;29 Suppl 12:S47-52. doi: 10.1097/BOT.0000000000000462. Review.

PMID:
26584267
45.

Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells.

Mattout A, Aaronson Y, Sailaja BS, Raghu Ram EV, Harikumar A, Mallm JP, Sim KH, Nissim-Rafinia M, Supper E, Singh PB, Sze SK, Gasser SM, Rippe K, Meshorer E.

Genome Biol. 2015 Sep 28;16:213. doi: 10.1186/s13059-015-0760-8.

46.

Chromatin states and nuclear organization in development--a view from the nuclear lamina.

Mattout A, Cabianca DS, Gasser SM.

Genome Biol. 2015 Aug 25;16:174. doi: 10.1186/s13059-015-0747-5. Review.

47.

Genome-derived cytosolic DNA contributes to type I interferon expression and immunogenicity of B-cell lymphoma cells.

Shen YJ, Ho SSW, Tan NY, Koo CX, Khatoo M, Cheung FSG, Gasser S.

Cytokine. 2015 Dec;76(2):581-582. doi: 10.1016/j.cyto.2015.05.024. Epub 2015 Jun 9.

PMID:
26070935
48.

Nuclear organization in DNA end processing: Telomeres vs double-strand breaks.

Marcomini I, Gasser SM.

DNA Repair (Amst). 2015 Aug;32:134-40. doi: 10.1016/j.dnarep.2015.04.024. Epub 2015 May 1. Review.

PMID:
26004856
49.

Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability.

Su XA, Dion V, Gasser SM, Freudenreich CH.

Genes Dev. 2015 May 15;29(10):1006-17. doi: 10.1101/gad.256404.114. Epub 2015 May 4.

50.

Repeat DNA in genome organization and stability.

Padeken J, Zeller P, Gasser SM.

Curr Opin Genet Dev. 2015 Apr;31:12-9. doi: 10.1016/j.gde.2015.03.009. Epub 2015 Apr 29. Review.

PMID:
25917896

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