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Items: 1 to 50 of 143

1.

Molecular determinants for agonist recognition and discrimination in P2X2 receptors.

Gasparri F, Wengel J, Grutter T, Pless SA.

J Gen Physiol. 2019 Jul 1;151(7):898-911. doi: 10.1085/jgp.201912347. Epub 2019 May 24.

PMID:
31126967
2.

A Water-Soluble Microencapsulated Milk Thistle Extract as Active Ingredient for Dermal Formulations.

Esposito T, Sansone F, Russo P, Picerno P, Aquino RP, Gasparri F, Mencherini T.

Molecules. 2019 Apr 19;24(8). pii: E1547. doi: 10.3390/molecules24081547.

3.

Natural dietary antioxidants containing flavonoids modulate keratinocytes physiology: In vitro tri-culture models.

Bassino E, Gasparri F, Munaron L.

J Ethnopharmacol. 2019 Jun 28;238:111844. doi: 10.1016/j.jep.2019.111844. Epub 2019 Mar 30.

PMID:
30940568
4.

Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate.

Raposo Moreira Dias A, Pina A, Dean A, Lerchen HG, Caruso M, Gasparri F, Fraietta I, Troiani S, Arosio D, Belvisi L, Pignataro L, Dal Corso A, Gennari C.

Chemistry. 2019 Feb 1;25(7):1696-1700. doi: 10.1002/chem.201805447. Epub 2018 Dec 27.

5.

Serenoa repens and N-acetyl glucosamine/milk proteins complex differentially affect the paracrine communication between endothelial and follicle dermal papilla cells.

Bassino E, Gasparri F, Munaron L.

J Cell Physiol. 2019 May;234(5):7320-7329. doi: 10.1002/jcp.27491. Epub 2018 Nov 12.

PMID:
30417926
6.

Application of Spray Drying Particle Engineering to a High-Functionality/Low-Solubility Milk Thistle Extract: Powders Production and Characterization.

Sansone F, Esposito T, Lauro MR, Picerno P, Mencherini T, Gasparri F, De Santis S, Chieppa M, Cirillo C, Aquino RP.

Molecules. 2018 Jul 14;23(7). pii: E1716. doi: 10.3390/molecules23071716.

7.

Efficacy of Teeth Whitening with a Mouthwash: In Vitro and In Vivo Approaches.

Gasparri F, Schemehorn BR, Zanardi A.

J Clin Dent. 2018 Mar;29(1):13-17.

PMID:
29758152
8.

Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury.

Magnaghi P, Salom B, Cozzi L, Amboldi N, Ballinari D, Tamborini E, Gasparri F, Montagnoli A, Raddrizzani L, Somaschini A, Bosotti R, Orrenius C, Bozzi F, Pilotti S, Galvani A, Sommer J, Stacchiotti S, Isacchi A.

Mol Cancer Ther. 2018 Mar;17(3):603-613. doi: 10.1158/1535-7163.MCT-17-0324. Epub 2017 Dec 13.

9.

Milk thistle and olive extract: old substances with a new mission against sun-induced skin damage.

DI Caprio R, Monfrecola G, Gasparri F, Micillo R, Balato A, Lembo S.

G Ital Dermatol Venereol. 2017 Nov 30. doi: 10.23736/S0392-0488.17.05726-1. [Epub ahead of print]

PMID:
29192469
10.

Pleiotropic Effects of White Willow Bark and 1,2-Decanediol on Human Adult Keratinocytes.

Bassino E, Gasparri F, Munaron L.

Skin Pharmacol Physiol. 2018;31(1):10-18. doi: 10.1159/000481690. Epub 2017 Nov 8.

11.

The anti-inflammatory and antioxidant properties of 1,2-decanediol and willow bark extract in lipopolysaccharide-stimulated keratinocytes.

DI Caprio R, Monfrecola G, Balato A, Balato N, Gasparri F, Micillo R, Lembo S.

G Ital Dermatol Venereol. 2017 Jul 13. doi: 10.23736/S0392-0488.17.05592-4. [Epub ahead of print]

PMID:
28712268
12.

Tumor Targeting with an isoDGR-Drug Conjugate.

Zanella S, Angerani S, Pina A, López Rivas P, Giannini C, Panzeri S, Arosio D, Caruso M, Gasparri F, Fraietta I, Albanese C, Marsiglio A, Pignataro L, Belvisi L, Piarulli U, Gennari C.

Chemistry. 2017 Jun 12;23(33):7910-7914. doi: 10.1002/chem.201701844. Epub 2017 May 26.

13.

Submicrometric hypromellose acetate succinate particles as carrier for soy isoflavones extract with improved skin penetration performance.

Del Gaudio P, Russo P, Rodriguez Dorado R, Sansone F, Mencherini T, Gasparri F, Aquino RP.

Carbohydr Polym. 2017 Jun 1;165:22-29. doi: 10.1016/j.carbpol.2017.02.025. Epub 2017 Feb 8.

PMID:
28363543
14.

Dermal-Epidermal Cross-Talk: Differential Interactions With Microvascular Endothelial Cells.

Bassino E, Vallariello E, Gasparri F, Munaron L.

J Cell Physiol. 2017 May;232(5):897-903. doi: 10.1002/jcp.25657. Epub 2016 Nov 10.

15.

The development of high-content screening (HCS) technology and its importance to drug discovery.

Fraietta I, Gasparri F.

Expert Opin Drug Discov. 2016;11(5):501-14. doi: 10.1517/17460441.2016.1165203. Epub 2016 Mar 28. Review.

PMID:
26971542
16.

Effects of flavonoid derivatives on human microvascular endothelial cells.

Bassino E, Antoniotti S, Gasparri F, Munaron L.

Nat Prod Res. 2016 Dec;30(24):2831-2834. doi: 10.1080/14786419.2016.1154053. Epub 2016 Mar 2.

17.

Effects of the biomimetic peptide Sh-Polypeptide 9 (CG-VEGF) on cocultures of human hair follicle dermal papilla cells and microvascular endothelial cells.

Bassino E, Zanardi A, Gasparri F, Munaron L.

Exp Dermatol. 2016 Mar;25(3):237-9. doi: 10.1111/exd.12906. Epub 2016 Feb 10. No abstract available.

18.

A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds.

Durlak M, Fugazza C, Elangovan S, Marini MG, Marongiu MF, Moi P, Fraietta I, Cappella P, Barbarani G, Font-Monclus I, Mauri M, Ottolenghi S, Gasparri F, Ronchi A.

PLoS One. 2015 Oct 28;10(10):e0141083. doi: 10.1371/journal.pone.0141083. eCollection 2015.

19.

Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening.

Anania M, Gasparri F, Cetti E, Fraietta I, Todoerti K, Miranda C, Mazzoni M, Re C, Colombo R, Ukmar G, Camisasca S, Pagliardini S, Pierotti M, Neri A, Galvani A, Greco A.

Oncotarget. 2015 Oct 27;6(33):34629-48. doi: 10.18632/oncotarget.5282.

20.

In vitro Percutaneous Absorption of Niacinamide and Phytosterols and in vivo Evaluation of their Effect on Skin Barrier Recovery.

Offerta A, Bonina F, Gasparri F, Zanardi A, Micicche L, Puglia C.

Curr Drug Deliv. 2016;13(1):111-20.

PMID:
26201345
21.

Cell Proliferation Method: Click Chemistry Based on BrdU Coupling for Multiplex Antibody Staining.

Cappella P, Gasparri F, Pulici M, Moll J.

Curr Protoc Cytom. 2015 Apr 1;72:7.34.1-17. doi: 10.1002/0471142956.cy0734s72.

PMID:
25827484
22.

Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers.

Dal Corso A, Caruso M, Belvisi L, Arosio D, Piarulli U, Albanese C, Gasparri F, Marsiglio A, Sola F, Troiani S, Valsasina B, Pignataro L, Donati D, Gennari C.

Chemistry. 2015 Apr 27;21(18):6921-9. doi: 10.1002/chem.201500158. Epub 2015 Mar 17.

PMID:
25784522
23.

Paracrine crosstalk between human hair follicle dermal papilla cells and microvascular endothelial cells.

Bassino E, Gasparri F, Giannini V, Munaron L.

Exp Dermatol. 2015 May;24(5):388-90. doi: 10.1111/exd.12670. Epub 2015 Mar 9.

24.

Application of click chemistry conditions for 5-bromo-2'-deoxyuridine determination through Fenton and related reactions.

Cappella P, Pulici M, Gasparri F.

Curr Protoc Cytom. 2015 Jan 5;71:7.43.1-17. doi: 10.1002/0471142956.cy0743s71.

PMID:
25559225
25.

Mcl-1 antagonism is a potential therapeutic strategy in a subset of solid cancers.

Modugno M, Banfi P, Gasparri F, Borzilleri R, Carter P, Cornelius L, Gottardis M, Lee V, Mapelli C, Naglich JG, Tebben A, Vite G, Pastori W, Albanese C, Corti E, Ballinari D, Galvani A.

Exp Cell Res. 2015 Mar 15;332(2):267-77. doi: 10.1016/j.yexcr.2014.11.022. Epub 2014 Dec 5.

PMID:
25486070
26.

Discovery of 2-(cyclohexylmethylamino)pyrimidines as a new class of reversible valosine containing protein inhibitors.

Cervi G, Magnaghi P, Asa D, Avanzi N, Badari A, Borghi D, Caruso M, Cirla A, Cozzi L, Felder E, Galvani A, Gasparri F, Lomolino A, Magnuson S, Malgesini B, Motto I, Pasi M, Rizzi S, Salom B, Sorrentino G, Troiani S, Valsasina B, O'Brien T, Isacchi A, Donati D, D'Alessio R.

J Med Chem. 2014 Dec 26;57(24):10443-54. doi: 10.1021/jm501313x. Epub 2014 Dec 12.

PMID:
25474526
27.

Optimization of diarylthiazole B-raf inhibitors: identification of a compound endowed with high oral antitumor activity, mitigated hERG inhibition, and low paradoxical effect.

Pulici M, Traquandi G, Marchionni C, Modugno M, Lupi R, Amboldi N, Casale E, Colombo N, Corti L, Fasolini M, Gasparri F, Pastori W, Scolaro A, Donati D, Felder E, Galvani A, Isacchi A, Pesenti E, Ciomei M.

ChemMedChem. 2015 Feb;10(2):276-95. doi: 10.1002/cmdc.201402424. Epub 2014 Nov 27.

PMID:
25430902
28.

The modulatory effect of ellagic acid and rosmarinic acid on ultraviolet-B-induced cytokine/chemokine gene expression in skin keratinocyte (HaCaT) cells.

Lembo S, Balato A, Di Caprio R, Cirillo T, Giannini V, Gasparri F, Monfrecola G.

Biomed Res Int. 2014;2014:346793. doi: 10.1155/2014/346793. Epub 2014 Aug 4.

29.

The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.

Ardini E, Bosotti R, Borgia AL, De Ponti C, Somaschini A, Cammarota R, Amboldi N, Raddrizzani L, Milani A, Magnaghi P, Ballinari D, Casero D, Gasparri F, Banfi P, Avanzi N, Saccardo MB, Alzani R, Bandiera T, Felder E, Donati D, Pesenti E, Sartore-Bianchi A, Gambacorta M, Pierotti MA, Siena S, Veronese S, Galvani A, Isacchi A.

Mol Oncol. 2014 Dec;8(8):1495-507. doi: 10.1016/j.molonc.2014.06.001. Epub 2014 Jun 12.

30.

Non-equivalent ligand selectivity of agonist sites in (α4β2)2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy.

Mazzaferro S, Gasparri F, New K, Alcaino C, Faundez M, Iturriaga Vasquez P, Vijayan R, Biggin PC, Bermudez I.

J Biol Chem. 2014 Aug 1;289(31):21795-806. doi: 10.1074/jbc.M114.555136. Epub 2014 Jun 16.

31.

Isoflavones in aglycone solution enhance ultraviolet B-induced DNA damage repair efficiency.

Iovine B, Garofalo M, Orefice M, Giannini V, Gasparri F, Monfrecola G, Bevilacqua MA.

Clin Exp Dermatol. 2014 Apr;39(3):391-4. doi: 10.1111/ced.12290.

PMID:
24635083
32.

Formulation strategies to modulate the topical delivery of anti-inflammatory compounds.

Puglia C, Rizza L, Offerta A, Gasparri F, Giannini V, Bonina F.

J Cosmet Sci. 2013 Sep-Oct;64(5):341-53.

PMID:
24139433
33.

From "Click" to "Fenton" chemistry for 5-bromo-2'-deoxyuridine determination.

Cappella P, Giansanti V, Pulici M, Gasparri F.

Cytometry A. 2013 Nov;83(11):989-1000. doi: 10.1002/cyto.a.22343. Epub 2013 Aug 13.

34.

Highly multiplexed phenotypic imaging for cell proliferation studies.

Cappella P, Gasparri F.

J Biomol Screen. 2014 Jan;19(1):145-57. doi: 10.1177/1087057113495712. Epub 2013 Jul 29.

PMID:
23896684
35.

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death.

Magnaghi P, D'Alessio R, Valsasina B, Avanzi N, Rizzi S, Asa D, Gasparri F, Cozzi L, Cucchi U, Orrenius C, Polucci P, Ballinari D, Perrera C, Leone A, Cervi G, Casale E, Xiao Y, Wong C, Anderson DJ, Galvani A, Donati D, O'Brien T, Jackson PK, Isacchi A.

Nat Chem Biol. 2013 Sep;9(9):548-56. doi: 10.1038/nchembio.1313. Epub 2013 Jul 28.

PMID:
23892893
36.

Cell line identity finding by fingerprinting, an optimized resource for short tandem repeat profile authentication.

Somaschini A, Amboldi N, Nuzzo A, Scacheri E, Ukmar G, Ballinari D, Malyszko J, Raddrizzani L, Landonio A, Gasparri F, Galvani A, Isacchi A, Bosotti R.

Genet Test Mol Biomarkers. 2013 Mar;17(3):254-9. doi: 10.1089/gtmb.2012.0359. Epub 2013 Jan 28.

PMID:
23356232
37.

A comparative analysis of the photo-protective effects of soy isoflavones in their aglycone and glucoside forms.

Iovine B, Iannella ML, Gasparri F, Giannini V, Monfrecola G, Bevilacqua MA.

Int J Mol Sci. 2012 Dec 4;13(12):16444-56. doi: 10.3390/ijms131216444.

38.

Synergic Effect of Genistein and Daidzein on UVB-Induced DNA Damage: An Effective Photoprotective Combination.

Iovine B, Iannella ML, Gasparri F, Monfrecola G, Bevilacqua MA.

J Biomed Biotechnol. 2011;2011:692846. doi: 10.1155/2011/692846. Epub 2011 Jul 13.

39.

Additional acetylcholine (ACh) binding site at alpha4/alpha4 interface of (alpha4beta2)2alpha4 nicotinic receptor influences agonist sensitivity.

Mazzaferro S, Benallegue N, Carbone A, Gasparri F, Vijayan R, Biggin PC, Moroni M, Bermudez I.

J Biol Chem. 2011 Sep 2;286(35):31043-54. doi: 10.1074/jbc.M111.262014. Epub 2011 Jul 14.

42.

Thymidine kinase 1 expression defines an activated G1 state of the cell cycle as revealed with site-specific antibodies and ArrayScan assays.

Gasparri F, Wang N, Skog S, Galvani A, Eriksson S.

Eur J Cell Biol. 2009 Dec;88(12):779-85. doi: 10.1016/j.ejcb.2009.06.005. Epub 2009 Sep 2.

PMID:
19726104
43.

An overview of cell phenotypes in HCS: limitations and advantages.

Gasparri F.

Expert Opin Drug Discov. 2009 Jun;4(6):643-57. doi: 10.1517/17460440902992870.

PMID:
23489157
44.

Cell proliferation method: click chemistry based on BrdU coupling for multiplex antibody staining.

Cappella P, Gasparri F, Pulici M, Moll J.

Curr Protoc Cytom. 2008 Jul;Chapter 7:Unit7.34. doi: 10.1002/0471142956.cy0734s45.

PMID:
18770651
45.

High-content analysis of kinase activity in cells.

Gasparri F, Sola F, Bandiera T, Moll J, Galvani A.

Comb Chem High Throughput Screen. 2008 Aug;11(7):523-36. Review.

PMID:
18694389
46.
47.

Bortezomib inhibits nuclear factor-kappaB dependent survival and has potent in vivo activity in mesothelioma.

Sartore-Bianchi A, Gasparri F, Galvani A, Nici L, Darnowski JW, Barbone D, Fennell DA, Gaudino G, Porta C, Mutti L.

Clin Cancer Res. 2007 Oct 1;13(19):5942-51. Erratum in: Clin Cancer Res. 2007 Nov 1;13(21):6543.

48.

Cell-cycle inhibitor profiling by high-content analysis.

Gasparri F, Ciavolella A, Galvani A.

Adv Exp Med Biol. 2007;604:137-48. Review.

PMID:
17695726
49.

Multiparametric cell cycle analysis by automated microscopy.

Gasparri F, Cappella P, Galvani A.

J Biomol Screen. 2006 Sep;11(6):586-98. Epub 2006 Jul 14.

PMID:
16844964
50.

Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high-content screening reader.

Gasparri F, Mariani M, Sola F, Galvani A.

Drug Discov Today. 2005 Autumn;Suppl:31-42.

PMID:
23570164

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