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Items: 1 to 50 of 135

1.

Plasticity in the Human Gut Microbiome Defies Evolutionary Constraints.

Gomez A, Sharma AK, Mallott EK, Petrzelkova KJ, Jost Robinson CA, Yeoman CJ, Carbonero F, Pafco B, Rothman JM, Ulanov A, Vlckova K, Amato KR, Schnorr SL, Dominy NJ, Modry D, Todd A, Torralba M, Nelson KE, Burns MB, Blekhman R, Remis M, Stumpf RM, Wilson BA, Gaskins HR, Garber PA, White BA, Leigh SR.

mSphere. 2019 Jul 31;4(4). pii: e00271-19. doi: 10.1128/mSphere.00271-19.

2.

The 'in vivo lifestyle' of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice.

Ridlon JM, Devendran S, Alves JM, Doden H, Wolf PG, Pereira GV, Ly L, Volland A, Takei H, Nittono H, Murai T, Kurosawa T, Chlipala GE, Green SJ, Hernandez AG, Fields CJ, Wright CL, Kakiyama G, Cann I, Kashyap P, McCracken V, Gaskins HR.

Gut Microbes. 2019 Jun 9:1-24. doi: 10.1080/19490976.2019.1618173. [Epub ahead of print]

PMID:
31177942
3.

International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis.

Scott AJ, Alexander JL, Merrifield CA, Cunningham D, Jobin C, Brown R, Alverdy J, O'Keefe SJ, Gaskins HR, Teare J, Yu J, Hughes DJ, Verstraelen H, Burton J, O'Toole PW, Rosenberg DW, Marchesi JR, Kinross JM.

Gut. 2019 Sep;68(9):1624-1632. doi: 10.1136/gutjnl-2019-318556. Epub 2019 May 15.

4.

Hypoxia activates enhanced invasive potential and endogenous hyaluronic acid production by glioblastoma cells.

Chen JE, Lumibao J, Blazek A, Gaskins HR, Harley B.

Biomater Sci. 2018 Mar 26;6(4):854-862. doi: 10.1039/c7bm01195d.

5.

Design considerations for open-well microfluidic platforms for hypoxic cell studies.

Byrne MB, Leslie MT, Patel HS, Gaskins HR, Kenis PJA.

Biomicrofluidics. 2017 Oct 27;11(5):054116. doi: 10.1063/1.4998579. eCollection 2017 Sep.

6.

Airyscan super-resolution microscopy of mitochondrial morphology and dynamics in living tumor cells.

Kolossov VL, Sivaguru M, Huff J, Luby K, Kanakaraju K, Gaskins HR.

Microsc Res Tech. 2018 Feb;81(2):115-128. doi: 10.1002/jemt.22968. Epub 2017 Nov 13.

PMID:
29131445
7.

Reproducibility of assessing fecal microbiota in chronic constipation.

Parthasarathy G, Chen J, Chia N, O'Connor HM, Gaskins HR, Bharucha AE.

Neurogastroenterol Motil. 2017 Oct;29(10):1-10. doi: 10.1111/nmo.13172. Epub 2017 Jul 28.

8.

Assessing the colonic microbiome, hydrogenogenic and hydrogenotrophic genes, transit and breath methane in constipation.

Wolf PG, Parthasarathy G, Chen J, O'Connor HM, Chia N, Bharucha AE, Gaskins HR.

Neurogastroenterol Motil. 2017 Oct;29(10):1-9. doi: 10.1111/nmo.13056. Epub 2017 Mar 13.

9.

Zinc enhances intestinal epithelial barrier function through the PI3K/AKT/mTOR signaling pathway in Caco-2 cells.

Shao Y, Wolf PG, Guo S, Guo Y, Gaskins HR, Zhang B.

J Nutr Biochem. 2017 May;43:18-26. doi: 10.1016/j.jnutbio.2017.01.013. Epub 2017 Jan 31.

PMID:
28193579
10.

Race-dependent association of sulfidogenic bacteria with colorectal cancer.

Yazici C, Wolf PG, Kim H, Cross TL, Vermillion K, Carroll T, Augustus GJ, Mutlu E, Tussing-Humphreys L, Braunschweig C, Xicola RM, Jung B, Llor X, Ellis NA, Gaskins HR.

Gut. 2017 Nov;66(11):1983-1994. doi: 10.1136/gutjnl-2016-313321. Epub 2017 Feb 2.

11.

Distinct responses of compartmentalized glutathione redox potentials to pharmacologic quinones targeting NQO1.

Kolossov VL, Ponnuraj N, Beaudoin JN, Leslie MT, Kenis PJ, Gaskins HR.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):680-686. doi: 10.1016/j.bbrc.2016.12.082. Epub 2016 Dec 14.

12.

H2 metabolism is widespread and diverse among human colonic microbes.

Wolf PG, Biswas A, Morales SE, Greening C, Gaskins HR.

Gut Microbes. 2016 May 3;7(3):235-45. doi: 10.1080/19490976.2016.1182288.

13.

Taurocholic acid metabolism by gut microbes and colon cancer.

Ridlon JM, Wolf PG, Gaskins HR.

Gut Microbes. 2016 May 3;7(3):201-15. doi: 10.1080/19490976.2016.1150414. Epub 2016 Mar 22. Review.

14.

Gut Microbiome of Coexisting BaAka Pygmies and Bantu Reflects Gradients of Traditional Subsistence Patterns.

Gomez A, Petrzelkova KJ, Burns MB, Yeoman CJ, Amato KR, Vlckova K, Modry D, Todd A, Jost Robinson CA, Remis MJ, Torralba MG, Morton E, Umaña JD, Carbonero F, Gaskins HR, Nelson KE, Wilson BA, Stumpf RM, White BA, Leigh SR, Blekhman R.

Cell Rep. 2016 Mar 8;14(9):2142-2153. doi: 10.1016/j.celrep.2016.02.013. Epub 2016 Feb 25.

15.

Exercise and gut immune function: evidence of alterations in colon immune cell homeostasis and microbiome characteristics with exercise training.

Cook MD, Allen JM, Pence BD, Wallig MA, Gaskins HR, White BA, Woods JA.

Immunol Cell Biol. 2016 Feb;94(2):158-63. doi: 10.1038/icb.2015.108. Epub 2015 Dec 2. Review.

PMID:
26626721
16.

Pseudomonas aeruginosa pyocyanin modulates mucin glycosylation with sialyl-Lewis(x) to increase binding to airway epithelial cells.

Jeffries JL, Jia J, Choi W, Choe S, Miao J, Xu Y, Powell R, Lin J, Kuang Z, Gaskins HR, Lau GW.

Mucosal Immunol. 2016 Jul;9(4):1039-1050. doi: 10.1038/mi.2015.119. Epub 2015 Nov 11.

17.

Relationship Between Microbiota of the Colonic Mucosa vs Feces and Symptoms, Colonic Transit, and Methane Production in Female Patients With Chronic Constipation.

Parthasarathy G, Chen J, Chen X, Chia N, O'Connor HM, Wolf PG, Gaskins HR, Bharucha AE.

Gastroenterology. 2016 Feb;150(2):367-79.e1. doi: 10.1053/j.gastro.2015.10.005. Epub 2015 Oct 13.

18.

Table grape consumption reduces adiposity and markers of hepatic lipogenesis and alters gut microbiota in butter fat-fed mice.

Baldwin J, Collins B, Wolf PG, Martinez K, Shen W, Chuang CC, Zhong W, Cooney P, Cockrell C, Chang E, Gaskins HR, McIntosh MK.

J Nutr Biochem. 2016 Jan;27:123-35. doi: 10.1016/j.jnutbio.2015.08.027. Epub 2015 Sep 2.

19.

Thiol-based antioxidants elicit mitochondrial oxidation via respiratory complex III.

Kolossov VL, Beaudoin JN, Ponnuraj N, DiLiberto SJ, Hanafin WP, Kenis PJ, Gaskins HR.

Am J Physiol Cell Physiol. 2015 Jul 15;309(2):C81-91.

20.

Fat, fibre and cancer risk in African Americans and rural Africans.

O'Keefe SJ, Li JV, Lahti L, Ou J, Carbonero F, Mohammed K, Posma JM, Kinross J, Wahl E, Ruder E, Vipperla K, Naidoo V, Mtshali L, Tims S, Puylaert PG, DeLany J, Krasinskas A, Benefiel AC, Kaseb HO, Newton K, Nicholson JK, de Vos WM, Gaskins HR, Zoetendal EG.

Nat Commun. 2015 Apr 28;6:6342. doi: 10.1038/ncomms7342.

21.

Gut microbiome composition and metabolomic profiles of wild western lowland gorillas (Gorilla gorilla gorilla) reflect host ecology.

Gomez A, Petrzelkova K, Yeoman CJ, Vlckova K, Mrázek J, Koppova I, Carbonero F, Ulanov A, Modry D, Todd A, Torralba M, Nelson KE, Gaskins HR, Wilson B, Stumpf RM, White BA, Leigh SR.

Mol Ecol. 2015 May;24(10):2551-65. doi: 10.1111/mec.13181.

PMID:
25846719
22.

Voluntary and forced exercise differentially alters the gut microbiome in C57BL/6J mice.

Allen JM, Berg Miller ME, Pence BD, Whitlock K, Nehra V, Gaskins HR, White BA, Fryer JD, Woods JA.

J Appl Physiol (1985). 2015 Apr 15;118(8):1059-66. doi: 10.1152/japplphysiol.01077.2014. Epub 2015 Feb 12.

23.

Galacto-oligosaccharides may directly enhance intestinal barrier function through the modulation of goblet cells.

Bhatia S, Prabhu PN, Benefiel AC, Miller MJ, Chow J, Davis SR, Gaskins HR.

Mol Nutr Food Res. 2015 Mar;59(3):566-73. doi: 10.1002/mnfr.201400639. Epub 2014 Dec 28.

PMID:
25421108
24.

Microfluidic platform for the study of intercellular communication via soluble factor-cell and cell-cell paracrine signaling.

Byrne MB, Trump L, Desai AV, Schook LB, Gaskins HR, Kenis PJ.

Biomicrofluidics. 2014 Jul 10;8(4):044104. doi: 10.1063/1.4887098. eCollection 2014 Jul.

25.

Methods to study the tumor microenvironment under controlled oxygen conditions.

Byrne MB, Leslie MT, Gaskins HR, Kenis PJA.

Trends Biotechnol. 2014 Nov;32(11):556-563. doi: 10.1016/j.tibtech.2014.09.006. Epub 2014 Oct 2. Review.

26.

Intestinal and systemic inflammatory responses are positively associated with sulfidogenic bacteria abundance in high-fat-fed male C57BL/6J mice.

Shen W, Wolf PG, Carbonero F, Zhong W, Reid T, Gaskins HR, McIntosh MK.

J Nutr. 2014 Aug;144(8):1181-7. doi: 10.3945/jn.114.194332. Epub 2014 Jun 11.

PMID:
24919690
27.

Effects of dietary clays on performance and intestinal mucus barrier of broiler chicks challenged with Salmonella enterica serovar Typhimurium and on goblet cell function in vitro.

Almeida JA, Ponnuraj NP, Lee JJ, Utterback P, Gaskins HR, Dilger RN, Pettigrew JE.

Poult Sci. 2014 Apr;93(4):839-47. doi: 10.3382/ps.2013-03587.

PMID:
24706960
28.

Circadian clock gene expression regulates cancer cell growth through glutaminase.

Huang A, Bao B, Gaskins HR, Liu H, Zhang X, Lu L, Gao S, Shi Y, Zhang M, Shan Y, Feng J, Yao G.

Acta Biochim Biophys Sin (Shanghai). 2014 May;46(5):409-14. doi: 10.1093/abbs/gmu012. Epub 2014 Mar 28.

PMID:
24681885
29.

Inhibition of glutathione synthesis distinctly alters mitochondrial and cytosolic redox poise.

Kolossov VL, Hanafin WP, Beaudoin JN, Bica DE, DiLiberto SJ, Kenis PJ, Gaskins HR.

Exp Biol Med (Maywood). 2014 Apr;239(4):394-403. doi: 10.1177/1535370214522179. Epub 2014 Feb 28.

30.

Escherichia coli challenge and one type of smectite alter intestinal barrier of pigs.

Almeida JA, Liu Y, Song M, Lee JJ, Gaskins HR, Maddox CW, Osuna O, Pettigrew JE.

J Anim Sci Biotechnol. 2013 Dec 20;4(1):52. doi: 10.1186/2049-1891-4-52.

31.

Influence of dietary fat on intestinal microbes, inflammation, barrier function and metabolic outcomes.

Shen W, Gaskins HR, McIntosh MK.

J Nutr Biochem. 2014 Mar;25(3):270-80. doi: 10.1016/j.jnutbio.2013.09.009. Epub 2013 Oct 29. Review.

PMID:
24355793
32.

Transient light-induced intracellular oxidation revealed by redox biosensor.

Kolossov VL, Beaudoin JN, Hanafin WP, DiLiberto SJ, Kenis PJ, Gaskins HR.

Biochem Biophys Res Commun. 2013 Oct 4;439(4):517-21. doi: 10.1016/j.bbrc.2013.09.011. Epub 2013 Sep 8.

33.

Hydrogenotrophic microbiota distinguish native Africans from African and European Americans.

Nava GM, Carbonero F, Ou J, Benefiel AC, O'Keefe SJ, Gaskins HR.

Environ Microbiol Rep. 2012 Jun;4(3):307-15. doi: 10.1111/j.1758-2229.2012.00334.x. Epub 2012 Mar 12.

34.

Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans.

Ou J, Carbonero F, Zoetendal EG, DeLany JP, Wang M, Newton K, Gaskins HR, O'Keefe SJ.

Am J Clin Nutr. 2013 Jul;98(1):111-20. doi: 10.3945/ajcn.112.056689. Epub 2013 May 29.

35.

Mode of delivery and early nutrition modulate microbial colonization and fermentation products in neonatal piglets.

Wang M, Radlowski EC, Monaco MH, Fahey GC Jr, Gaskins HR, Donovan SM.

J Nutr. 2013 Jun;143(6):795-803. doi: 10.3945/jn.112.173096. Epub 2013 Apr 24.

PMID:
23616518
36.

An improved method for collecting breath from 3- to 7-year-old children.

Wang AA, Paige KN, Gaskins HR, Teran-Garcia M.

JPEN J Parenter Enteral Nutr. 2014 May;38(4):507-9. doi: 10.1177/0148607113483178. Epub 2013 Mar 28.

PMID:
23538295
37.

Habitat degradation impacts black howler monkey (Alouatta pigra) gastrointestinal microbiomes.

Amato KR, Yeoman CJ, Kent A, Righini N, Carbonero F, Estrada A, Gaskins HR, Stumpf RM, Yildirim S, Torralba M, Gillis M, Wilson BA, Nelson KE, White BA, Leigh SR.

ISME J. 2013 Jul;7(7):1344-53. doi: 10.1038/ismej.2013.16. Epub 2013 Mar 14.

38.

Farnesoid X receptor expression is decreased in colonic mucosa of patients with primary sclerosing cholangitis and colitis-associated neoplasia.

Torres J, Bao X, Iuga AC, Chen A, Harpaz N, Ullman T, Cohen BL, Pineton de Chambrun G, Asciutti S, Odin JA, Sachar DB, Gaskins HR, Setchell K, Colombel JF, Itzkowitz SH.

Inflamm Bowel Dis. 2013 Feb;19(2):275-82. doi: 10.1097/MIB.0b013e318286ff2e.

PMID:
23348121
39.

Microbial pathways in colonic sulfur metabolism and links with health and disease.

Carbonero F, Benefiel AC, Alizadeh-Ghamsari AH, Gaskins HR.

Front Physiol. 2012 Nov 28;3:448. doi: 10.3389/fphys.2012.00448. eCollection 2012.

40.

Förster resonance energy transfer-based sensor targeting endoplasmic reticulum reveals highly oxidative environment.

Kolossov VL, Leslie MT, Chatterjee A, Sheehan BM, Kenis PJ, Gaskins HR.

Exp Biol Med (Maywood). 2012 Jun;237(6):652-62. doi: 10.1258/ebm.2012.011436. Epub 2012 Jun 19.

41.

Contributions of the microbial hydrogen economy to colonic homeostasis.

Carbonero F, Benefiel AC, Gaskins HR.

Nat Rev Gastroenterol Hepatol. 2012 Sep;9(9):504-18. doi: 10.1038/nrgastro.2012.85. Epub 2012 May 15. Review.

PMID:
22585131
42.

Effect of fiber supplementation on the microbiota in critically ill patients.

O'Keefe SJ, Ou J, Delany JP, Curry S, Zoetendal E, Gaskins HR, Gunn S.

World J Gastrointest Pathophysiol. 2011 Dec 15;2(6):138-45. doi: 10.4291/wjgp.v2.i6.138.

43.

Pseudomonas aeruginosa pyocyanin causes airway goblet cell hyperplasia and metaplasia and mucus hypersecretion by inactivating the transcriptional factor FoxA2.

Hao Y, Kuang Z, Walling BE, Bhatia S, Sivaguru M, Chen Y, Gaskins HR, Lau GW.

Cell Microbiol. 2012 Mar;14(3):401-15. doi: 10.1111/j.1462-5822.2011.01727.x. Epub 2011 Dec 28.

PMID:
22103442
44.

Inflammatory cues modulate the expression of secretory product genes, Golgi sulfotransferases and sulfomucin production in LS174T cells.

Croix JA, Bhatia S, Gaskins HR.

Exp Biol Med (Maywood). 2011 Dec;236(12):1402-12. doi: 10.1258/ebm.2011.011186. Epub 2011 Nov 18.

PMID:
22101519
45.

Pyrosequencing-based analysis of the mucosal microbiota in healthy individuals reveals ubiquitous bacterial groups and micro-heterogeneity.

Hong PY, Croix JA, Greenberg E, Gaskins HR, Mackie RI.

PLoS One. 2011;6(9):e25042. doi: 10.1371/journal.pone.0025042. Epub 2011 Sep 22.

46.

On the relationship between sialomucin and sulfomucin expression and hydrogenotrophic microbes in the human colonic mucosa.

Croix JA, Carbonero F, Nava GM, Russell M, Greenberg E, Gaskins HR.

PLoS One. 2011;6(9):e24447. doi: 10.1371/journal.pone.0024447. Epub 2011 Sep 9.

47.

Microbial DNA extraction from intestinal biopsies is improved by avoiding mechanical cell disruption.

Carbonero F, Nava GM, Benefiel AC, Greenberg E, Gaskins HR.

J Microbiol Methods. 2011 Oct;87(1):125-7. doi: 10.1016/j.mimet.2011.07.014. Epub 2011 Jul 23.

48.

Abundance and diversity of mucosa-associated hydrogenotrophic microbes in the healthy human colon.

Nava GM, Carbonero F, Croix JA, Greenberg E, Gaskins HR.

ISME J. 2012 Jan;6(1):57-70. doi: 10.1038/ismej.2011.90. Epub 2011 Jul 14.

49.

Development of a high-dynamic range, GFP-based FRET probe sensitive to oxidative microenvironments.

Kolossov VL, Spring BQ, Clegg RM, Henry JJ, Sokolowski A, Kenis PJ, Gaskins HR.

Exp Biol Med (Maywood). 2011 Jun 1;236(6):681-91. doi: 10.1258/ebm.2011.011009. Epub 2011 May 23.

50.

Analysis of the hydrogenotrophic microbiota of wild and captive black howler monkeys (Alouatta pigra) in palenque national park, Mexico.

Nakamura N, Amato KR, Garber P, Estrada A, Mackie RI, Gaskins HR.

Am J Primatol. 2011 Sep;73(9):909-19. doi: 10.1002/ajp.20961. Epub 2011 May 9.

PMID:
21557284

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