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Items: 17


Development of a novel, sensitive cell-based corin assay.

Lambertz P, Theisen L, Längst N, Garvie CW, MacDonald BT, Yu J, Elowe NH, Zubov D, Kaushik VK, Wunder F.

Biochem Pharmacol. 2019 Feb;160:62-70. doi: 10.1016/j.bcp.2018.12.009. Epub 2018 Dec 13.


The Autophagy-Related Beclin-1 Protein Requires the Coiled-Coil and BARA Domains To Form a Homodimer with Submicromolar Affinity.

Ranaghan MJ, Durney MA, Mesleh MF, McCarren PR, Garvie CW, Daniels DS, Carey KL, Skepner AP, Levine B, Perez JR.

Biochemistry. 2017 Dec 26;56(51):6639-6651. doi: 10.1021/acs.biochem.7b00936. Epub 2017 Dec 14.


Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor.

Garvie CW, Fraley CV, Elowe NH, Culyba EK, Lemke CT, Hubbard BK, Kaushik VK, Daniels DS.

Protein Sci. 2016 Nov;25(11):2018-2027. doi: 10.1002/pro.3019. Epub 2016 Oct 15.


A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein.

Pop MS, Stransky N, Garvie CW, Theurillat JP, Hartman EC, Lewis TA, Zhong C, Culyba EK, Lin F, Daniels DS, Pagliarini R, Ronco L, Koehler AN, Garraway LA.

Mol Cancer Ther. 2014 Jun;13(6):1492-502. doi: 10.1158/1535-7163.MCT-13-0689. Epub 2014 Apr 15.


Mechanistic insights into RNase L through use of an MDMX-derived multi-functional protein domain.

Garvie CW, Vasanthavada K, Xiang Q.

Biochim Biophys Acta. 2013 Aug;1834(8):1562-71. doi: 10.1016/j.bbapap.2013.04.010. Epub 2013 Apr 19.


Solution-based approach to study binding to the eIF4E cap-binding site using CD spectroscopy.

Garvie CW.

Anal Biochem. 2013 Mar 1;434(1):166-71. doi: 10.1016/j.ab.2012.11.020. Epub 2012 Dec 5.


Solution structure of the heterotrimeric complex between the interaction domains of RFX5 and RFXAP from the RFX gene regulatory complex.

Laird KM, Briggs LL, Boss JM, Summers MF, Garvie CW.

J Mol Biol. 2010 Oct 15;403(1):40-51. doi: 10.1016/j.jmb.2010.08.025. Epub 2010 Aug 21.


Highly cooperative recruitment of Ets-1 and release of autoinhibition by Pax5.

Fitzsimmons D, Lukin K, Lutz R, Garvie CW, Wolberger C, Hagman J.

J Mol Biol. 2009 Sep 18;392(2):452-64. doi: 10.1016/j.jmb.2009.07.028. Epub 2009 Jul 17.


Formation of the RFX gene regulatory complex induces folding of the interaction domain of RFXAP.

Briggs L, Laird K, Boss JM, Garvie CW.

Proteins. 2009 Aug 15;76(3):655-64. doi: 10.1002/prot.22379.


Assembly of the RFX complex on the MHCII promoter: role of RFXAP and RFXB in relieving autoinhibition of RFX5.

Garvie CW, Boss JM.

Biochim Biophys Acta. 2008 Dec;1779(12):797-804. doi: 10.1016/j.bbagrm.2008.07.012. Epub 2008 Aug 6.


Characterization of the RFX complex and the RFX5(L66A) mutant: implications for the regulation of MHC class II gene expression.

Garvie CW, Stagno JR, Reid S, Singh A, Harrington E, Boss JM.

Biochemistry. 2007 Feb 13;46(6):1597-611. Epub 2007 Jan 20.


Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP).

Maier H, Ostraat R, Parenti S, Fitzsimmons D, Abraham LJ, Garvie CW, Hagman J.

Nucleic Acids Res. 2003 Oct 1;31(19):5483-9.


Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships.

Garvie CW, Pufall MA, Graves BJ, Wolberger C.

J Biol Chem. 2002 Nov 22;277(47):45529-36. Epub 2002 Sep 6.


Structural and functional studies of an intermediate on the pathway to operator binding by Escherichia coli MetJ.

He YY, Garvie CW, Elworthy S, Manfield IW, McNally T, Lawrenson ID, Phillips SE, Stockley PG.

J Mol Biol. 2002 Jun 28;320(1):39-53.


Structural studies of Ets-1/Pax5 complex formation on DNA.

Garvie CW, Hagman J, Wolberger C.

Mol Cell. 2001 Dec;8(6):1267-76.


Recognition of specific DNA sequences.

Garvie CW, Wolberger C.

Mol Cell. 2001 Nov;8(5):937-46. Review.


Direct and indirect readout in mutant Met repressor-operator complexes.

Garvie CW, Phillips SE.

Structure. 2000 Sep 15;8(9):905-14.

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