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Items: 23

1.

Anti-KIT Monoclonal Antibody Treatment Enhances the Antitumor Activity of Immune Checkpoint Inhibitors by Reversing Tumor-Induced Immunosuppression.

Garton AJ, Seibel S, Lopresti-Morrow L, Crew L, Janson N, Mandiyan S, Trombetta ES, Pankratz S, LaVallee TM, Gedrich R.

Mol Cancer Ther. 2017 Apr;16(4):671-680. doi: 10.1158/1535-7163.MCT-16-0676. Epub 2017 Jan 30.

2.

KTN0158, a Humanized Anti-KIT Monoclonal Antibody, Demonstrates Biologic Activity against both Normal and Malignant Canine Mast Cells.

London CA, Gardner HL, Rippy S, Post G, La Perle K, Crew L, Lopresti-Morrow L, Garton AJ, McMahon G, LaVallee TM, Gedrich R.

Clin Cancer Res. 2017 May 15;23(10):2565-2574. doi: 10.1158/1078-0432.CCR-16-2152. Epub 2016 Nov 4.

3.

Emerging Receptor Tyrosine Kinase Drug Targets: Implications for Antibody-Based Therapies for Oncology and Immunologic Disorders.

LaVallee TM, Alvarado D, Garton AJ, Trombetta ES, Gedrich R, McMahon G.

Crit Rev Oncog. 2015;20(5-6):485-508. doi: 10.1615/CritRevOncog.v20.i5-6.170. Review.

PMID:
27279243
4.

ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion.

Vigil D, Kim TY, Plachco A, Garton AJ, Castaldo L, Pachter JA, Dong H, Chen X, Tokar B, Campbell SL, Der CJ.

Cancer Res. 2012 Oct 15;72(20):5338-47. doi: 10.1158/0008-5472.CAN-11-2373. Epub 2012 Aug 31.

5.

Quantitative high-throughput cell-based assays for inhibitors of ROCK kinases.

Garton AJ, Castaldo L, Pachter JA.

Methods Enzymol. 2008;439:491-500. doi: 10.1016/S0076-6879(07)00433-8.

PMID:
18374184
6.

Kinetic analysis of epidermal growth factor receptor somatic mutant proteins shows increased sensitivity to the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib.

Carey KD, Garton AJ, Romero MS, Kahler J, Thomson S, Ross S, Park F, Haley JD, Gibson N, Sliwkowski MX.

Cancer Res. 2006 Aug 15;66(16):8163-71.

7.

OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models.

Garton AJ, Crew AP, Franklin M, Cooke AR, Wynne GM, Castaldo L, Kahler J, Winski SL, Franks A, Brown EN, Bittner MA, Keily JF, Briner P, Hidden C, Srebernak MC, Pirrit C, O'Connor M, Chan A, Vulevic B, Henninger D, Hart K, Sennello R, Li AH, Zhang T, Richardson F, Emerson DL, Castelhano AL, Arnold LD, Gibson NW.

Cancer Res. 2006 Jan 15;66(2):1015-24.

8.

Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST.

Garton AJ, Tonks NK.

J Biol Chem. 1999 Feb 5;274(6):3811-8.

9.
10.

Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation.

MacKintosh C, Garton AJ, McDonnell A, Barford D, Cohen PT, Tonks NK, Cohen P.

FEBS Lett. 1996 Nov 18;397(2-3):235-8.

11.
12.

Evidence for a multi-domain structure for hormone-sensitive lipase.

Smith GM, Garton AJ, Aitken A, Yeaman SJ.

FEBS Lett. 1996 Oct 28;396(1):90-4.

13.

Beam data measurements for dynamic wedges on Varian 600C (6 MV) and 2100C (6 and 10 MV) linear accelerators.

Bidmead AM, Garton AJ, Childs PJ.

Phys Med Biol. 1995 Mar;40(3):393-411.

PMID:
7732070
14.
15.

Estimation of tube potential in mammography from transmission measurements.

Garton AJ, Dance DR.

Phys Med Biol. 1994 Aug;39(8):1247-61.

PMID:
15551565
16.

Domain structure of hormone-sensitive lipase.

Smith GM, Garton AJ, Aitken A, Yeaman SJ.

Biochem Soc Trans. 1993 Aug;21 ( Pt 3)(3):233S. No abstract available.

PMID:
8224390
17.

Identification and role of the basal phosphorylation site on hormone-sensitive lipase.

Garton AJ, Yeaman SJ.

Eur J Biochem. 1990 Jul 20;191(1):245-50.

18.

Regulation of maxi-K+ channels on pancreatic duct cells by cyclic AMP-dependent phosphorylation.

Gray MA, Greenwell JR, Garton AJ, Argent BE.

J Membr Biol. 1990 May;115(3):203-15.

PMID:
1695685
19.

The presence and role of hormone-sensitive lipase in heart muscle.

Small CA, Garton AJ, Yeaman SJ.

Biochem J. 1989 Feb 15;258(1):67-72.

20.

Phosphorylation of bovine hormone-sensitive lipase by the AMP-activated protein kinase. A possible antilipolytic mechanism.

Garton AJ, Campbell DG, Carling D, Hardie DG, Colbran RJ, Yeaman SJ.

Eur J Biochem. 1989 Jan 15;179(1):249-54.

21.

Hormone-sensitive lipase is involved in the hydrolysis of lipoidal derivatives of estrogens and other steroid hormones.

Lee FT, Adams JB, Garton AJ, Yeaman SJ.

Biochim Biophys Acta. 1988 Nov 25;963(2):258-64.

PMID:
3196730
22.
23.

Regulation of cholesterol ester hydrolase by cyclic AMP-dependent protein kinase.

Colbran RJ, Garton AJ, Cordle SR, Yeaman SJ.

FEBS Lett. 1986 Jun 9;201(2):257-61.

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