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Items: 37

1.

Ets1 Controls the Development of B Cell Autoimmune Responses in a Cell-Intrinsic Manner.

Sunshine A, Goich D, Stith A, Sortino K, Dalton J, Metcalfe S, Svensson EC, Garrett-Sinha LA.

Immunohorizons. 2019 Jul 17;3(7):331-340. doi: 10.4049/immunohorizons.1900033.

PMID:
31356162
2.

Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma.

Gluck C, Glathar A, Tsompana M, Nowak N, Garrett-Sinha LA, Buck MJ, Sinha S.

PLoS Genet. 2019 Jul 15;15(7):e1008250. doi: 10.1371/journal.pgen.1008250. eCollection 2019 Jul.

3.

IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate.

Noviski M, Mueller JL, Satterthwaite A, Garrett-Sinha LA, Brombacher F, Zikherman J.

Elife. 2018 Mar 9;7. pii: e35074. doi: 10.7554/eLife.35074.

4.

Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB.

Willis SN, Tellier J, Liao Y, Trezise S, Light A, O'Donnell K, Garrett-Sinha LA, Shi W, Tarlinton DM, Nutt SL.

Nat Commun. 2017 Nov 10;8(1):1426. doi: 10.1038/s41467-017-01605-1.

5.

Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1.

Saelee P, Kearly A, Nutt SL, Garrett-Sinha LA.

Front Immunol. 2017 Apr 7;8:383. doi: 10.3389/fimmu.2017.00383. eCollection 2017.

6.

The Role of the Transcription Factor Ets1 in Lupus and Other Autoimmune Diseases.

Garrett-Sinha LA, Kearly A, Satterthwaite AB.

Crit Rev Immunol. 2016;36(6):485-510. doi: 10.1615/CritRevImmunol.2017020284.

7.

Requirement for Transcription Factor Ets1 in B Cell Tolerance to Self-Antigens.

Russell L, John S, Cullen J, Luo W, Shlomchik MJ, Garrett-Sinha LA.

J Immunol. 2015 Oct 15;195(8):3574-83. doi: 10.4049/jimmunol.1500776. Epub 2015 Sep 9.

8.

Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels.

Mayeux J, Skaug B, Luo W, Russell LM, John S, Saelee P, Abbasi H, Li QZ, Garrett-Sinha LA, Satterthwaite AB.

J Immunol. 2015 Sep 1;195(5):1955-63. doi: 10.4049/jimmunol.1500165. Epub 2015 Jul 24.

9.

CD28 Promotes Plasma Cell Survival, Sustained Antibody Responses, and BLIMP-1 Upregulation through Its Distal PYAP Proline Motif.

Rozanski CH, Utley A, Carlson LM, Farren MR, Murray M, Russell LM, Nair JR, Yang Z, Brady W, Garrett-Sinha LA, Schoenberger SP, Green JM, Boise LH, Lee KP.

J Immunol. 2015 May 15;194(10):4717-28. doi: 10.4049/jimmunol.1402260. Epub 2015 Apr 1.

10.

A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels.

Luo W, Mayeux J, Gutierrez T, Russell L, Getahun A, Müller J, Tedder T, Parnes J, Rickert R, Nitschke L, Cambier J, Satterthwaite AB, Garrett-Sinha LA.

J Immunol. 2014 Jul 15;193(2):909-920. doi: 10.4049/jimmunol.1400666. Epub 2014 Jun 13.

11.

Deletion of IFT20 in early stage T lymphocyte differentiation inhibits the development of collagen-induced arthritis.

Yuan X, Garrett-Sinha LA, Sarkar D, Yang S.

Bone Res. 2014 Nov 18;2:14038. doi: 10.1038/boneres.2014.38. eCollection 2014.

12.

Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.

Chin SS, Romano RA, Nagarajan P, Sinha S, Garrett-Sinha LA.

Biol Open. 2013 Dec 15;2(12):1336-45. doi: 10.1242/bio.20135397.

13.

Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation.

John S, Russell L, Chin SS, Luo W, Oshima R, Garrett-Sinha LA.

Mol Cell Biol. 2014 Feb;34(3):522-32. doi: 10.1128/MCB.00612-13. Epub 2013 Nov 25.

14.

The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.

Agudo J, Ruzo A, Tung N, Salmon H, Leboeuf M, Hashimoto D, Becker C, Garrett-Sinha LA, Baccarini A, Merad M, Brown BD.

Nat Immunol. 2014 Jan;15(1):54-62. doi: 10.1038/ni.2767. Epub 2013 Nov 24.

15.

A unique form of haptoglobin produced by murine hematopoietic cells supports B-cell survival, differentiation and immune response.

Huntoon KM, Russell L, Tracy E, Barbour KW, Li Q, Shrikant PA, Berger FG, Garrett-Sinha LA, Baumann H.

Mol Immunol. 2013 Oct;55(3-4):345-54. doi: 10.1016/j.molimm.2013.03.008. Epub 2013 Mar 30.

16.

Review of Ets1 structure, function, and roles in immunity.

Garrett-Sinha LA.

Cell Mol Life Sci. 2013 Sep;70(18):3375-90. doi: 10.1007/s00018-012-1243-7. Epub 2013 Jan 5. Review.

17.

Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C.

DeKoter RP, Geadah M, Khoosal S, Xu LS, Thillainadesan G, Torchia J, Chin SS, Garrett-Sinha LA.

J Immunol. 2010 Dec 15;185(12):7374-84. doi: 10.4049/jimmunol.1001413. Epub 2010 Nov 5.

18.

Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators.

Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA.

J Cell Sci. 2010 Oct 15;123(Pt 20):3566-75. doi: 10.1242/jcs.062240.

19.

Transcription factor Ets-1 in cytokine and chemokine gene regulation.

Russell L, Garrett-Sinha LA.

Cytokine. 2010 Sep;51(3):217-26. doi: 10.1016/j.cyto.2010.03.006. Epub 2010 Apr 7. Review.

PMID:
20378371
20.

Deletion of ETS-1, a gene in the Jacobsen syndrome critical region, causes ventricular septal defects and abnormal ventricular morphology in mice.

Ye M, Coldren C, Liang X, Mattina T, Goldmuntz E, Benson DW, Ivy D, Perryman MB, Garrett-Sinha LA, Grossfeld P.

Hum Mol Genet. 2010 Feb 15;19(4):648-56. doi: 10.1093/hmg/ddp532. Epub 2009 Nov 26.

21.

Ets1 induces dysplastic changes when expressed in terminally-differentiating squamous epidermal cells.

Nagarajan P, Parikh N, Garrett-Sinha LA, Sinha S.

PLoS One. 2009;4(1):e4179. doi: 10.1371/journal.pone.0004179. Epub 2009 Jan 14.

22.

Blimp1: a conserved transcriptional repressor critical for differentiation of many tissues.

John SA, Garrett-Sinha LA.

Exp Cell Res. 2009 Apr 15;315(7):1077-84. doi: 10.1016/j.yexcr.2008.11.015. Epub 2008 Dec 3. Review.

PMID:
19073176
23.

IP3 receptor-mediated Ca2+ release in naive CD4 T cells dictates their cytokine program.

Nagaleekar VK, Diehl SA, Juncadella I, Charland C, Muthusamy N, Eaton S, Haynes L, Garrett-Sinha LA, Anguita J, Rincón M.

J Immunol. 2008 Dec 15;181(12):8315-22.

24.

Isolation and characterization of an immortalized oral keratinocyte cell line of mouse origin.

Parikh N, Nagarajan P, Sei-ichi M, Sinha S, Garrett-Sinha LA.

Arch Oral Biol. 2008 Nov;53(11):1091-100. doi: 10.1016/j.archoralbio.2008.07.002. Epub 2008 Aug 21.

25.

IL-17 and the Th17 lineage in systemic lupus erythematosus.

Garrett-Sinha LA, John S, Gaffen SL.

Curr Opin Rheumatol. 2008 Sep;20(5):519-25. doi: 10.1097/BOR.0b013e328304b6b5. Review.

PMID:
18698171
26.

Ets-1 regulates plasma cell differentiation by interfering with the activity of the transcription factor Blimp-1.

John SA, Clements JL, Russell LM, Garrett-Sinha LA.

J Biol Chem. 2008 Jan 11;283(2):951-62. Epub 2007 Oct 31.

27.

Impaired generation of CD8+ thymocytes in Ets-1-deficient mice.

Clements JL, John SA, Garrett-Sinha LA.

J Immunol. 2006 Jul 15;177(2):905-12.

28.

Ets-1 deficiency leads to altered B cell differentiation, hyperresponsiveness to TLR9 and autoimmune disease.

Wang D, John SA, Clements JL, Percy DH, Barton KP, Garrett-Sinha LA.

Int Immunol. 2005 Sep;17(9):1179-91. Epub 2005 Jul 28.

PMID:
16051621
29.

Spi-1 and Spi-B control the expression of the Grap2 gene in B cells.

Garrett-Sinha LA, Hou P, Wang D, Grabiner B, Araujo E, Rao S, Yun TJ, Clark EA, Simon MC, Clark MR.

Gene. 2005 Jun 20;353(1):134-46.

PMID:
15936902
30.

Enforced expression of Spi-B reverses T lineage commitment and blocks beta-selection.

Lefebvre JM, Haks MC, Carleton MO, Rhodes M, Sinnathamby G, Simon MC, Eisenlohr LC, Garrett-Sinha LA, Wiest DL.

J Immunol. 2005 May 15;174(10):6184-94.

31.

PU.1/Spi-B regulation of c-rel is essential for mature B cell survival.

Hu CJ, Rao S, Ramirez-Bergeron DL, Garrett-Sinha LA, Gerondakis S, Clark MR, Simon MC.

Immunity. 2001 Oct;15(4):545-55.

32.

PU.1 exhibits partial functional redundancy with Spi-B, but not with Ets-1 or Elf-1.

Garrett-Sinha LA, Dahl R, Rao S, Barton KP, Simon MC.

Blood. 2001 May 1;97(9):2908-12.

33.

Klf6 is a zinc finger protein expressed in a cell-specific manner during kidney development.

Fischer EA, Verpont MC, Garrett-Sinha LA, Ronco PM, Rossert JA.

J Am Soc Nephrol. 2001 Apr;12(4):726-35.

34.

The Ets factors PU.1 and Spi-B regulate the transcription in vivo of P2Y10, a lymphoid restricted heptahelical receptor.

Rao S, Garrett-Sinha LA, Yoon J, Simon MC.

J Biol Chem. 1999 Nov 26;274(48):34245-52.

35.

PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction.

Garrett-Sinha LA, Su GH, Rao S, Kabak S, Hao Z, Clark MR, Simon MC.

Immunity. 1999 Apr;10(4):399-408.

36.

Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B.

Su GH, Chen HM, Muthusamy N, Garrett-Sinha LA, Baunoch D, Tenen DG, Simon MC.

EMBO J. 1997 Dec 1;16(23):7118-29.

37.

A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells.

Garrett-Sinha LA, Eberspaecher H, Seldin MF, de Crombrugghe B.

J Biol Chem. 1996 Dec 6;271(49):31384-90.

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