Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41

1.

LRIG1 extracellular domain: structure and function analysis.

Xu Y, Soo P, Walker F, Zhang HH, Redpath N, Tan CW, Nicola NA, Adams TE, Garrett TP, Zhang JG, Burgess AW.

J Mol Biol. 2015 May 22;427(10):1934-48. doi: 10.1016/j.jmb.2015.03.001. Epub 2015 Mar 9.

2.

Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1.

Redpath NT, Xu Y, Wilson NJ, Fabri LJ, Baca M, Andrews AE, Braley H, Lu P, Ireland C, Ernst RE, Woods A, Forrest G, An Z, Zaller DM, Strohl WR, Luo CS, Czabotar PE, Garrett TP, Hilton DJ, Nash AD, Zhang JG, Nicola NA.

Biochem J. 2013 Apr 15;451(2):165-75. doi: 10.1042/BJ20121819.

PMID:
23384096
3.

Ligand binding induces a conformational change in epidermal growth factor receptor dimers.

Walker F, Rothacker J, Henderson C, Nice EC, Catimel B, Zhang HH, Scott AM, Bailey MF, Orchard SG, Adams TE, Liu Z, Garrett TP, Clayton AH, Burgess AW.

Growth Factors. 2012 Dec;30(6):394-409. doi: 10.3109/08977194.2012.739619. Epub 2012 Nov 20.

PMID:
23163584
4.

Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.

Xu Y, Kershaw NJ, Luo CS, Soo P, Pocock MJ, Czabotar PE, Hilton DJ, Nicola NA, Garrett TP, Zhang JG.

J Biol Chem. 2010 Jul 9;285(28):21214-8. doi: 10.1074/jbc.C110.129502. Epub 2010 May 20.

5.

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR.

Garrett TP, Burgess AW, Gan HK, Luwor RB, Cartwright G, Walker F, Orchard SG, Clayton AH, Nice EC, Rothacker J, Catimel B, Cavenee WK, Old LJ, Stockert E, Ritter G, Adams TE, Hoyne PA, Wittrup D, Chao G, Cochran JR, Luo C, Lou M, Huyton T, Xu Y, Fairlie WD, Yao S, Scott AM, Johns TG.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5082-7. doi: 10.1073/pnas.0811559106. Epub 2009 Mar 16.

6.

An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.

Huyton T, Zhang JG, Luo CS, Lou MZ, Hilton DJ, Nicola NA, Garrett TP.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12737-42. Epub 2007 Jul 24.

7.

Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding.

Smith BJ, Huyton T, Joosten RP, McKimm-Breschkin JL, Zhang JG, Luo CS, Lou MZ, Labrou NE, Garrett TP.

Acta Crystallogr D Biol Crystallogr. 2006 Sep;62(Pt 9):947-52. Epub 2006 Aug 19.

PMID:
16929094
8.

The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity.

Lou M, Garrett TP, McKern NM, Hoyne PA, Epa VC, Bentley JD, Lovrecz GO, Cosgrove LJ, Frenkel MJ, Ward CW.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12429-34. Epub 2006 Aug 7.

9.

Structural relationships between the insulin receptor and epidermal growth factor receptor families and other proteins.

Ward CW, Garrett TP.

Curr Opin Drug Discov Devel. 2004 Sep;7(5):630-8. Review.

PMID:
15503865
10.

CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor.

Walker F, Orchard SG, Jorissen RN, Hall NE, Zhang HH, Hoyne PA, Adams TE, Johns TG, Ward C, Garrett TP, Zhu HJ, Nerrie M, Scott AM, Nice EC, Burgess AW.

J Biol Chem. 2004 May 21;279(21):22387-98. Epub 2004 Mar 11.

11.

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors.

Burgess AW, Cho HS, Eigenbrot C, Ferguson KM, Garrett TP, Leahy DJ, Lemmon MA, Sliwkowski MX, Ward CW, Yokoyama S.

Mol Cell. 2003 Sep;12(3):541-52. Review.

12.

Epidermal growth factor receptor: mechanisms of activation and signalling.

Jorissen RN, Walker F, Pouliot N, Garrett TP, Ward CW, Burgess AW.

Exp Cell Res. 2003 Mar 10;284(1):31-53. Review.

PMID:
12648464
13.

The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors.

Garrett TP, McKern NM, Lou M, Elleman TC, Adams TE, Lovrecz GO, Kofler M, Jorissen RN, Nice EC, Burgess AW, Ward CW.

Mol Cell. 2003 Feb;11(2):495-505.

14.

The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: implications for diabody flexibility.

Carmichael JA, Power BE, Garrett TP, Yazaki PJ, Shively JE, Raubischek AA, Wu AM, Hudson PJ.

J Mol Biol. 2003 Feb 14;326(2):341-51.

PMID:
12559905
15.

Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha.

Garrett TP, McKern NM, Lou M, Elleman TC, Adams TE, Lovrecz GO, Zhu HJ, Walker F, Frenkel MJ, Hoyne PA, Jorissen RN, Nice EC, Burgess AW, Ward CW.

Cell. 2002 Sep 20;110(6):763-73.

17.

Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain.

Elleman TC, Domagala T, McKern NM, Nerrie M, Lönnqvist B, Adams TE, Lewis J, Lovrecz GO, Hoyne PA, Richards KM, Howlett GJ, Rothacker J, Jorissen RN, Lou M, Garrett TP, Burgess AW, Nice EC, Ward CW.

Biochemistry. 2001 Jul 31;40(30):8930-9.

PMID:
11467954
18.

Mutant barley (1-->3,1-->4)-beta-glucan endohydrolases with enhanced thermostability.

Stewart RJ, Varghese JN, Garrett TP, Høj PB, Fincher GB.

Protein Eng. 2001 Apr;14(4):245-53.

PMID:
11391016
19.

The three dimensional structure of the type I insulin-like growth factor receptor.

Ward CW, Garrett TP, McKern NM, Lou M, Cosgrove LJ, Sparrow LG, Frenkel MJ, Hoyne PA, Elleman TC, Adams TE, Lovrecz GO, Lawrence LJ, Tulloch PA.

Mol Pathol. 2001 Jun;54(3):125-32. Review.

20.

Structure and function of the type 1 insulin-like growth factor receptor.

Adams TE, Epa VC, Garrett TP, Ward CW.

Cell Mol Life Sci. 2000 Jul;57(7):1050-93. Review.

PMID:
10961344
21.

Characterization of a comparative model of the extracellular domain of the epidermal growth factor receptor.

Jorissen RN, Epa VC, Treutlein HR, Garrett TP, Ward CW, Burgess AW.

Protein Sci. 2000 Feb;9(2):310-24.

22.

Biochemical analysis and crystallisation of Fc gamma RIIa, the low affinity receptor for IgG.

Powell MS, Barton PA, Emmanouilidis D, Wines BD, Neumann GM, Peitersz GA, Maxwell KF, Garrett TP, Hogarth PM.

Immunol Lett. 1999 May 3;68(1):17-23.

PMID:
10397151
23.

Congenital insulin resistance associated with a conformational alteration in a conserved beta-sheet in the insulin receptor L1 domain.

Rouard M, Bass J, Grigorescu F, Garrett TP, Ward CW, Lipkind G, Jaffiole C, Steiner DF, Bell GI.

J Biol Chem. 1999 Jun 25;274(26):18487-91.

24.

Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa.

Maxwell KF, Powell MS, Hulett MD, Barton PA, McKenzie IF, Garrett TP, Hogarth PM.

Nat Struct Biol. 1999 May;6(5):437-42.

PMID:
10331870
25.

Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor.

Garrett TP, McKern NM, Lou M, Frenkel MJ, Bentley JD, Lovrecz GO, Elleman TC, Cosgrove LJ, Ward CW.

Nature. 1998 Jul 23;394(6691):395-9.

PMID:
9690478
26.

Crystallization of the first three domains of the human insulin-like growth factor-1 receptor.

McKern NM, Lou M, Frenkel MJ, Verkuylen A, Bentley JD, Lovrecz GO, Ivancic N, Elleman TC, Garrett TP, Cosgrove LJ, Ward CW.

Protein Sci. 1997 Dec;6(12):2663-6.

27.

Polysaccharide hydrolases in germinated barley and their role in the depolymerization of plant and fungal cell walls.

Hrmova M, Banik M, Harvey AJ, Garrett TP, Varghese JN, Høj PB, Fincher GB.

Int J Biol Macromol. 1997 Aug;21(1-2):67-72. Review.

PMID:
9283018
28.
30.

A tetrad of ionizable amino acids is important for catalysis in barley beta-glucanases.

Chen L, Garrett TP, Fincher GB, Høj PB.

J Biol Chem. 1995 Apr 7;270(14):8093-101.

31.

Three-dimensional structures of two plant beta-glucan endohydrolases with distinct substrate specificities.

Varghese JN, Garrett TP, Colman PM, Chen L, Høj PB, Fincher GB.

Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2785-9.

32.

Refinement and analysis of the structure of the first two domains of human CD4.

Garrett TP, Wang J, Yan Y, Liu J, Harrison SC.

J Mol Biol. 1993 Dec 5;234(3):763-78.

PMID:
8254672
33.

Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.

Guo HC, Jardetzky TS, Garrett TP, Lane WS, Strominger JL, Wiley DC.

Nature. 1992 Nov 26;360(6402):364-6.

PMID:
1448153
34.

Positioning of a peptide in the cleft of HLA-A2 by complementing amino acid changes.

Latron F, Moots R, Rothbard JB, Garrett TP, Strominger JL, McMichael A.

Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11325-9.

35.

Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains.

Wang JH, Yan YW, Garrett TP, Liu JH, Rodgers DW, Garlick RL, Tarr GE, Husain Y, Reinherz EL, Harrison SC.

Nature. 1990 Nov 29;348(6300):411-8.

PMID:
1701030
36.

A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2.

Salter RD, Benjamin RJ, Wesley PK, Buxton SE, Garrett TP, Clayberger C, Krensky AM, Norment AM, Littman DR, Parham P.

Nature. 1990 May 3;345(6270):41-6.

PMID:
2109837
37.

Specificity pockets for the side chains of peptide antigens in HLA-Aw68.

Garrett TP, Saper MA, Bjorkman PJ, Strominger JL, Wiley DC.

Nature. 1989 Dec 7;342(6250):692-6.

PMID:
2594067
38.

Structure/function studies of major histocompatibility antigens.

Garrett TP, Saper MA, Samraoui B, Bjorkman PJ, Wiley DC.

Transplant Proc. 1989 Feb;21(1 Pt 1):588-90. Review. No abstract available.

PMID:
2650202
39.

Comparison of orthorhombic and monoclinic crystal structures of HLA-A2.

Madden DR, Saper MA, Garrett TP, Bjorkman PJ, Strominger JL, Wiley DC.

Cold Spring Harb Symp Quant Biol. 1989;54 Pt 1:353-9. No abstract available.

PMID:
2639758
40.

The crystal structure of poplar apoplastocyanin at 1.8-A resolution. The geometry of the copper-binding site is created by the polypeptide.

Garrett TP, Clingeleffer DJ, Guss JM, Rogers SJ, Freeman HC.

J Biol Chem. 1984 Mar 10;259(5):2822-5.

41.

Preliminary crystallographic data for plastocyanins from an alga (Enteromorpha prolifera) and from cucumber (Cucumis sativus).

Freeman HC, Garrett TP, Guss JM, Murata M, Yoshizaki F, Sugimura Y, Shimokoriyama M.

J Mol Biol. 1983 Feb 25;164(2):351-3.

PMID:
6842595

Supplemental Content

Loading ...
Support Center