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A multi-institutional comparison of younger and older adults with sickle cell disease.

Oyedeji C, Strouse JJ, Crawford RD, Garrett ME, Ashley-Koch AE, Telen MJ.

Am J Hematol. 2019 Jan 20. doi: 10.1002/ajh.25405. [Epub ahead of print] No abstract available.


A genome-wide association study of suicide attempts and suicidal ideation in U.S. military veterans.

Kimbrel NA, Garrett ME, Dennis MF; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, Hauser MA, Ashley-Koch AE, Beckham JC.

Psychiatry Res. 2018 Nov;269:64-69. doi: 10.1016/j.psychres.2018.07.017. Epub 2018 Jul 17.


Clinical and metabolomic risk factors associated with rapid renal function decline in sickle cell disease.

Xu JZ, Garrett ME, Soldano KL, Chen ST, Clish CB, Ashley-Koch AE, Telen MJ.

Am J Hematol. 2018 Dec;93(12):1451-1460. doi: 10.1002/ajh.25263. Epub 2018 Sep 27.


A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients.

Ilboudo Y, Bartolucci P, Garrett ME, Ashley-Koch A, Telen M, Brugnara C, Galactéros F, Lettre G.

Am J Hematol. 2018 Nov;93(11):E362-E365. doi: 10.1002/ajh.25245. Epub 2018 Sep 9. No abstract available.


Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia.

Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A, Fullard JF, Roussos P, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, White KP, Liu C, Reddy TE, Ashley-Koch A, Sullivan PF, Crawford GE.

Nat Commun. 2018 Aug 7;9(1):3121. doi: 10.1038/s41467-018-05379-y.


Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls.

Morey RA, Davis SL, Garrett ME, Haswell CC; Mid-Atlantic MIRECC Workgroup, Marx CE, Beckham JC, McCarthy G, Hauser MA, Ashley-Koch AE.

Transl Psychiatry. 2017 Nov 30;7(11):1265. doi: 10.1038/s41398-017-0021-6.


Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.

Ratanatharathorn A, Boks MP, Maihofer AX, Aiello AE, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Bromet E, Dennis M, Garrett ME, Geuze E, Guffanti G, Hauser MA, Kilaru V, Kimbrel NA, Koenen KC, Kuan PF, Logue MW, Luft BJ, Miller MW, Mitchell C, Nugent NR, Ressler KJ, Rutten BPF, Stein MB, Vermetten E, Vinkers CH, Youssef NA; VA Mid-Atlantic MIRECC Workgroup; PGC PTSD Epigenetics Workgroup, Uddin M, Nievergelt CM, Smith AK.

Am J Med Genet B Neuropsychiatr Genet. 2017 Sep;174(6):619-630. doi: 10.1002/ajmg.b.32568. Epub 2017 Jul 10.


The association of single-nucleotide polymorphisms in the oxytocin receptor and G protein-coupled receptor kinase 6 (GRK6) genes with oxytocin dosing requirements and labor outcomes.

Grotegut CA, Ngan E, Garrett ME, Miranda ML, Ashley-Koch AE, Swamy GK.

Am J Obstet Gynecol. 2017 Sep;217(3):367.e1-367.e9. doi: 10.1016/j.ajog.2017.05.023. Epub 2017 May 17.


Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.

Duncan LE, Ratanatharathorn A, Aiello AE, Almli LM, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Bierut LJ, Bisson J, Bradley B, Chen CY, Dalvie S, Farrer LA, Galea S, Garrett ME, Gelernter JE, Guffanti G, Hauser MA, Johnson EO, Kessler RC, Kimbrel NA, King A, Koen N, Kranzler HR, Logue MW, Maihofer AX, Martin AR, Miller MW, Morey RA, Nugent NR, Rice JP, Ripke S, Roberts AL, Saccone NL, Smoller JW, Stein DJ, Stein MB, Sumner JA, Uddin M, Ursano RJ, Wildman DE, Yehuda R, Zhao H, Daly MJ, Liberzon I, Ressler KJ, Nievergelt CM, Koenen KC.

Mol Psychiatry. 2018 Mar;23(3):666-673. doi: 10.1038/mp.2017.77. Epub 2017 Apr 25.


Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration.

Tan PL, Garrett ME, Willer JR, Campochiaro PA, Campochiaro B, Zack DJ, Ashley-Koch AE, Katsanis N.

Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1570-1576. doi: 10.1167/iovs.16-20867.


Thrombospondin-1 gene polymorphism is associated with estimated pulmonary artery pressure in patients with sickle cell anemia.

Jacob SA, Novelli EM, Isenberg JS, Garrett ME, Chu Y, Soldano K, Ataga KI, Telen MJ, Ashley-Koch A, Gladwin MT, Zhang Y, Kato GJ.

Am J Hematol. 2017 Mar;92(3):E31-E34. doi: 10.1002/ajh.24635. Epub 2017 Feb 3. No abstract available.


Automated identification of mouse visual areas with intrinsic signal imaging.

Juavinett AL, Nauhaus I, Garrett ME, Zhuang J, Callaway EM.

Nat Protoc. 2017 Jan;12(1):32-43. doi: 10.1038/nprot.2016.158. Epub 2016 Dec 1.


Further evidence for a role of the ADRB2 gene in risk for posttraumatic stress disorder.

Hauser MA, Garrett ME, Liu Y, Dennis MF, Kimbrel NA, Veterans Affairs Mid-Atlantic Mental Illness Research Education And Clinical Center Workgroup, Beckham JC, Ashley-Koch AE.

J Psychiatr Res. 2017 Jan;84:59-61. doi: 10.1016/j.jpsychires.2016.09.013. Epub 2016 Sep 17.


Phase 1 Study of a Sulforaphane-Containing Broccoli Sprout Homogenate for Sickle Cell Disease.

Doss JF, Jonassaint JC, Garrett ME, Ashley-Koch AE, Telen MJ, Chi JT.

PLoS One. 2016 Apr 12;11(4):e0152895. doi: 10.1371/journal.pone.0152895. eCollection 2016.


Correction: In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress.

Anderson BR, Howell DN, Soldano K, Garrett ME, Katsanis N, Telen MJ, Davis EE, Ashley-Koch AE.

PLoS Genet. 2015 Sep 17;11(9):e1005459. doi: 10.1371/journal.pgen.1005459. eCollection 2015 Sep. No abstract available.


Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder.

Kimbrel NA, Garrett ME, Dennis MF, Liu Y, Patanam I, Workgroup VM, Ashley-Koch AE, Hauser MA, Beckham JC.

Psychiatry Res. 2015 Sep 30;229(1-2):326-31. doi: 10.1016/j.psychres.2015.07.002. Epub 2015 Jul 8.


In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress.

Anderson BR, Howell DN, Soldano K, Garrett ME, Katsanis N, Telen MJ, Davis EE, Ashley-Koch AE.

PLoS Genet. 2015 Jul 6;11(7):e1005349. doi: 10.1371/journal.pgen.1005349. eCollection 2015 Jul. Erratum in: PLoS Genet. 2015 Sep;11(9):e1005459.


Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans.

Ashley-Koch AE, Garrett ME, Gibson J, Liu Y, Dennis MF, Kimbrel NA; Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, Beckham JC, Hauser MA.

J Affect Disord. 2015 Sep 15;184:225-34. doi: 10.1016/j.jad.2015.03.049. Epub 2015 Jun 12.


The Tec Kinase-Regulated Phosphoproteome Reveals a Mechanism for the Regulation of Inhibitory Signals in Murine Macrophages.

Tampella G, Kerns HM, Niu D, Singh S, Khim S, Bosch KA, Garrett ME, Moguche A, Evans E, Browning B, Jahan TA, Nacht M, Wolf-Yadlin A, Plebani A, Hamerman JA, Rawlings DJ, James RG.

J Immunol. 2015 Jul 1;195(1):246-56. doi: 10.4049/jimmunol.1403238. Epub 2015 May 29.


Pregnancy continuation and organizational religious activity following prenatal diagnosis of a lethal fetal defect are associated with improved psychological outcome.

Cope H, Garrett ME, Gregory S, Ashley-Koch A.

Prenat Diagn. 2015 Aug;35(8):761-768. doi: 10.1002/pd.4603. Epub 2015 May 26.


An examination of the association between 5-HTTLPR, combat exposure, and PTSD diagnosis among U.S. veterans.

Liu Y, Garrett ME, Dennis MF, Green KT; VA Mid-Atlantic MIRECC Registry Workgroup, Ashley-Koch AE, Hauser MA, Beckham JC, Kimbrel NA.

PLoS One. 2015 Mar 20;10(3):e0119998. doi: 10.1371/journal.pone.0119998. eCollection 2015.


Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation.

Lock EF, Soldano KL, Garrett ME, Cope H, Markunas CA, Fuchs H, Grant G, Dunson DB, Gregory SG, Ashley-Koch AE.

BMC Genomics. 2015 Jan 22;16:11. doi: 10.1186/s12864-014-1211-8.


Alloimmunization in sickle cell disease: changing antibody specificities and association with chronic pain and decreased survival.

Telen MJ, Afenyi-Annan A, Garrett ME, Combs MR, Orringer EP, Ashley-Koch AE.

Transfusion. 2015 Jun;55(6 Pt 2):1378-87. doi: 10.1111/trf.12940. Epub 2014 Dec 1.


DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma.

Liu Y, Garrett ME, Yaspan BL, Bailey JC, Loomis SJ, Brilliant M, Budenz DL, Christen WG, Fingert JH, Gaasterland D, Gaasterland T, Kang JH, Lee RK, Lichter P, Moroi SE, Realini A, Richards JE, Schuman JS, Scott WK, Singh K, Sit AJ, Vollrath D, Weinreb R, Wollstein G, Zack DJ, Zhang K, Pericak-Vance MA, Haines JL, Pasquale LR, Wiggs JL, Allingham RR, Ashley-Koch AE, Hauser MA.

Invest Ophthalmol Vis Sci. 2014 Nov 20;55(12):8251-8. doi: 10.1167/iovs.14-15712.


Angiogenic, neurotrophic, and inflammatory system SNPs moderate the association between birth weight and ADHD symptom severity.

Smith TF, Anastopoulos AD, Garrett ME, Arias-Vasquez A, Franke B, Oades RD, Sonuga-Barke E, Asherson P, Gill M, Buitelaar JK, Sergeant JA, Kollins SH, Faraone SV, Ashley-Koch A; IMAGE Consortium.

Am J Med Genet B Neuropsychiatr Genet. 2014 Dec;165B(8):691-704. doi: 10.1002/ajmg.b.32275. Epub 2014 Oct 25.


Topography and areal organization of mouse visual cortex.

Garrett ME, Nauhaus I, Marshel JH, Callaway EM.

J Neurosci. 2014 Sep 10;34(37):12587-600. doi: 10.1523/JNEUROSCI.1124-14.2014.


No association between RORA polymorphisms and PTSD in two independent samples.

Guffanti G, Ashley-Koch AE, Roberts AL, Garrett ME, Solovieff N, Ratanatharathorn A, De Vivo I, Dennis M, Ranu H, Smoller JW, Liu Y, Purcell SM; Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, Beckham J, Hauser MA, Koenen KC.

Mol Psychiatry. 2014 Oct;19(10):1056-7. doi: 10.1038/mp.2014.19. Epub 2014 Jul 22. No abstract available.


Missing genetic risk in neural tube defects: can exome sequencing yield an insight?

Krupp DR, Soldano KL, Garrett ME, Cope H, Ashley-Koch AE, Gregory SG.

Birth Defects Res A Clin Mol Teratol. 2014 Aug;100(8):642-6. doi: 10.1002/bdra.23276. Epub 2014 Jul 21.


Discovery and functional annotation of SIX6 variants in primary open-angle glaucoma.

Carnes MU, Liu YP, Allingham RR, Whigham BT, Havens S, Garrett ME, Qiao C; NEIGHBORHOOD Consortium Investigators, Katsanis N, Wiggs JL, Pasquale LR, Ashley-Koch A, Oh EC, Hauser MA.

PLoS Genet. 2014 May 29;10(5):e1004372. doi: 10.1371/journal.pgen.1004372. eCollection 2014.


Factors associated with survival in a contemporary adult sickle cell disease cohort.

Elmariah H, Garrett ME, De Castro LM, Jonassaint JC, Ataga KI, Eckman JR, Ashley-Koch AE, Telen MJ.

Am J Hematol. 2014 May;89(5):530-5. doi: 10.1002/ajh.23683. Epub 2014 Feb 21.


Genetic association analyses of nitric oxide synthase genes and neural tube defects vary by phenotype.

Soldano KL, Garrett ME, Cope HL, Rusnak JM, Ellis NJ, Dunlap KL, Speer MC, Gregory SG, Ashley-Koch AE.

Birth Defects Res B Dev Reprod Toxicol. 2013 Oct;98(5):365-73. doi: 10.1002/bdrb.21079. Epub 2013 Dec 9.


Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease.

Murphy SK, Yang H, Moylan CA, Pang H, Dellinger A, Abdelmalek MF, Garrett ME, Ashley-Koch A, Suzuki A, Tillmann HL, Hauser MA, Diehl AM.

Gastroenterology. 2013 Nov;145(5):1076-87. doi: 10.1053/j.gastro.2013.07.047. Epub 2013 Jul 31.


Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease.

Moylan CA, Pang H, Dellinger A, Suzuki A, Garrett ME, Guy CD, Murphy SK, Ashley-Koch AE, Choi SS, Michelotti GA, Hampton DD, Chen Y, Tillmann HL, Hauser MA, Abdelmalek MF, Diehl AM.

Hepatology. 2014 Feb;59(2):471-82. doi: 10.1002/hep.26661. Epub 2013 Dec 13.


Gene-centric association study of acute chest syndrome and painful crisis in sickle cell disease patients.

Galarneau G, Coady S, Garrett ME, Jeffries N, Puggal M, Paltoo D, Soldano K, Guasch A, Ashley-Koch AE, Telen MJ, Kutlar A, Lettre G, Papanicolaou GJ.

Blood. 2013 Jul 18;122(3):434-42. doi: 10.1182/blood-2013-01-478776. Epub 2013 May 29.


Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression.

Jamerson BD, Payne ME, Garrett ME, Ashley-Koch AE, Speer MC, Steffens DC.

Int J Geriatr Psychiatry. 2013 Sep;28(9):925-32. doi: 10.1002/gps.3899. Epub 2012 Dec 20.


IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian North American patients.

Garrett ME, Abdelmalek MF, Ashley-Koch A, Hauser MA, Moylan CA, Pang H, Diehl AM, Tillmann HL.

J Hepatol. 2013 Feb;58(2):402-3. doi: 10.1016/j.jhep.2012.09.035. Epub 2012 Oct 11. No abstract available.


A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

Milton JN, Sebastiani P, Solovieff N, Hartley SW, Bhatnagar P, Arking DE, Dworkis DA, Casella JF, Barron-Casella E, Bean CJ, Hooper WC, DeBaun MR, Garrett ME, Soldano K, Telen MJ, Ashley-Koch A, Gladwin MT, Baldwin CT, Steinberg MH, Klings ES.

PLoS One. 2012;7(4):e34741. doi: 10.1371/journal.pone.0034741. Epub 2012 Apr 27.


Functional specialization of seven mouse visual cortical areas.

Marshel JH, Garrett ME, Nauhaus I, Callaway EM.

Neuron. 2011 Dec 22;72(6):1040-54. doi: 10.1016/j.neuron.2011.12.004.


MYH9 and APOL1 are both associated with sickle cell disease nephropathy.

Ashley-Koch AE, Okocha EC, Garrett ME, Soldano K, De Castro LM, Jonassaint JC, Orringer EP, Eckman JR, Telen MJ.

Br J Haematol. 2011 Nov;155(3):386-94. doi: 10.1111/j.1365-2141.2011.08832.x. Epub 2011 Sep 13.


A preliminary analysis of interactions between genotype, retrospective ADHD symptoms, and initial reactions to smoking in a sample of young adults.

Bidwell LC, Garrett ME, McClernon FJ, Fuemmeler BF, Williams RB, Ashley-Koch AE, Kollins SH.

Nicotine Tob Res. 2012 Feb;14(2):229-33. doi: 10.1093/ntr/ntr125. Epub 2011 Jul 20.


Maternal vitamin D receptor genetic variation contributes to infant birthweight among black mothers.

Swamy GK, Garrett ME, Miranda ML, Ashley-Koch AE.

Am J Med Genet A. 2011 Jun;155A(6):1264-71. doi: 10.1002/ajmg.a.33583. Epub 2011 May 5.


The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects.

Rizzi TS, Arias-Vasquez A, Rommelse N, Kuntsi J, Anney R, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Ruano D, Van der Sluis S, Markunas CA, Garrett ME, Ashley-Koch AE, Kollins SH, Anastopoulos AD, Hansell NK, Wright MJ, Montgomery GW, Martin NG, Harris SE, Davies G, Tenesa A, Porteous DJ, Starr JM, Deary IJ, St Pourcain B, Davey Smith G, Timpson NJ, Evans DM, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Faraone SV, Franke B, Posthuma D.

Am J Med Genet B Neuropsychiatr Genet. 2011 Mar;156(2):145-57. doi: 10.1002/ajmg.b.31149. Epub 2010 Dec 16.


Self-Regulation of Emotion, Functional Impairment, and Comorbidity Among ChildrenWith AD/HD.

Anastopoulos AD, Smith TF, Garrett ME, Morrissey-Kane E, Schatz NK, Sommer JL, Kollins SH, Ashley-Koch A.

J Atten Disord. 2011 Oct;15(7):583-92. doi: 10.1177/1087054710370567. Epub 2010 Aug 4.


Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls.

Kring SI, Brummett BH, Barefoot J, Garrett ME, Ashley-Koch AE, Boyle SH, Siegler IC, Sørensen TI, Williams RB.

Psychosom Med. 2010 Jun;72(5):427-33. doi: 10.1097/PSY.0b013e3181de30ad. Epub 2010 May 13.


Genetic variants in SLC9A9 are associated with measures of attention-deficit/hyperactivity disorder symptoms in families.

Markunas CA, Quinn KS, Collins AL, Garrett ME, Lachiewicz AM, Sommer JL, Morrissey-Kane E, Kollins SH, Anastopoulos AD, Ashley-Koch AE.

Psychiatr Genet. 2010 Apr;20(2):73-81. doi: 10.1097/YPG.0b013e3283351209.


Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study.

Sebastiani P, Solovieff N, Hartley SW, Milton JN, Riva A, Dworkis DA, Melista E, Klings ES, Garrett ME, Telen MJ, Ashley-Koch A, Baldwin CT, Steinberg MH.

Am J Hematol. 2010 Jan;85(1):29-35. doi: 10.1002/ajh.21572.


Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster.

Solovieff N, Milton JN, Hartley SW, Sherva R, Sebastiani P, Dworkis DA, Klings ES, Farrer LA, Garrett ME, Ashley-Koch A, Telen MJ, Fucharoen S, Ha SY, Li CK, Chui DH, Baldwin CT, Steinberg MH.

Blood. 2010 Mar 4;115(9):1815-22. doi: 10.1182/blood-2009-08-239517. Epub 2009 Dec 16.


Effects of postnatal parental smoking on parent and teacher ratings of ADHD and oppositional symptoms.

Kollins SH, Garrett ME, McClernon FJ, Lachiewicz AM, Morrissey-Kane E, FitzGerald D, Collins AL, Anastopoulos AD, Ashley-Koch AE.

J Nerv Ment Dis. 2009 Jun;197(6):442-9. doi: 10.1097/NMD.0b013e3181a61d9e.


Interactions between genotype and depressive symptoms on obesity.

Fuemmeler BF, Agurs-Collins T, McClernon FJ, Kollins SH, Garrett ME, Ashley-Koch AE.

Behav Genet. 2009 May;39(3):296-305. doi: 10.1007/s10519-009-9266-z. Epub 2009 Apr 1.


SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.

Kollins SH, Anastopoulos AD, Lachiewicz AM, FitzGerald D, Morrissey-Kane E, Garrett ME, Keatts SL, Ashley-Koch AE.

Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5;147B(8):1580-8. doi: 10.1002/ajmg.b.30876.

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