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Items: 1 to 50 of 329

1.

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine.

Deshmukh AS, Peijs L, Beaudry JL, Jespersen NZ, Nielsen CH, Ma T, Brunner AD, Larsen TJ, Bayarri-Olmos R, Prabhakar BS, Helgstrand C, Severinsen MCK, Holst B, Kjaer A, Tang-Christensen M, Sanfridson A, Garred P, Privé GG, Pedersen BK, Gerhart-Hines Z, Nielsen S, Drucker DJ, Mann M, Scheele C.

Cell Metab. 2019 Nov 5;30(5):963-975.e7. doi: 10.1016/j.cmet.2019.10.001. Epub 2019 Oct 24.

PMID:
31668873
2.

Rapid and Efficient Purification of Functional Collectin-12 and Its Opsonic Activity against Fungal Pathogens.

Zhang J, Li A, Yang CQ, Garred P, Ma YJ.

J Immunol Res. 2019 Jul 29;2019:9164202. doi: 10.1155/2019/9164202. eCollection 2019.

3.

Combining MAP-1:CD35 or MAP-1:CD55 fusion proteins with pattern-recognition molecules as novel targeted modulators of the complement cascade.

Pérez-Alós L, Bayarri-Olmos R, Skjoedt MO, Garred P.

FASEB J. 2019 Nov;33(11):12723-12734. doi: 10.1096/fj.201901643R. Epub 2019 Aug 30.

PMID:
31469600
4.

Fatal pneumococcus meningitis in a child with complement factor ficolin-3 deficiency.

Dadfar E, Furuhjelm C, Nilsson J, Dahle C, Garred P.

J Allergy Clin Immunol Pract. 2019 Aug 10. pii: S2213-2198(19)30702-0. doi: 10.1016/j.jaip.2019.07.039. [Epub ahead of print] No abstract available.

PMID:
31408713
5.

Complement Nomenclature-Deconvoluted.

Bohlson SS, Garred P, Kemper C, Tenner AJ.

Front Immunol. 2019 Jun 7;10:1308. doi: 10.3389/fimmu.2019.01308. eCollection 2019.

6.

Plasma levels of mannose-binding lectin and future risk of venous thromboembolism.

Liang RA, Høiland II, Ueland T, Aukrust P, Snir O, Hindberg K, Braekkan SK, Garred P, Mollnes TE, Hansen JB.

J Thromb Haemost. 2019 Oct;17(10):1661-1669. doi: 10.1111/jth.14539. Epub 2019 Jul 1.

PMID:
31220397
7.

The impact of mannose-binding lectin polymorphisms on lung function in primary ciliary dyskinesia.

Videbaek K, Buchvald F, Holgersen MG, Henriksen A, Eriksson F, Garred P, Nielsen KG.

Pediatr Pulmonol. 2019 Aug;54(8):1182-1189. doi: 10.1002/ppul.24346. Epub 2019 Apr 22.

PMID:
31012247
8.

Decreased Ficolin-3-mediated Complement Lectin Pathway Activation and Alternative Pathway Amplification During Bacterial Infections in Patients With Type 2 Diabetes Mellitus.

Barkai LJ, Sipter E, Csuka D, Prohászka Z, Pilely K, Garred P, Hosszúfalusi N.

Front Immunol. 2019 Mar 20;10:509. doi: 10.3389/fimmu.2019.00509. eCollection 2019.

9.

The ficolin response to LPS challenge in mice.

Jarlhelt I, Genster N, Kirketerp-Møller N, Skjoedt MO, Garred P.

Mol Immunol. 2019 Apr;108:121-127. doi: 10.1016/j.molimm.2019.02.013. Epub 2019 Feb 26.

PMID:
30818229
10.

Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis.

Pilely K, Bakke SS, Palarasah Y, Skjoedt MO, Bartels ED, Espevik T, Garred P.

Atherosclerosis. 2019 Apr;283:35-42. doi: 10.1016/j.atherosclerosis.2019.01.034. Epub 2019 Feb 3.

PMID:
30772772
11.

Evasion of Classical Complement Pathway Activation on Plasmodium falciparum-Infected Erythrocytes Opsonized by PfEMP1-Specific IgG.

Larsen MD, Quintana MDP, Ditlev SB, Bayarri-Olmos R, Ofori MF, Hviid L, Garred P.

Front Immunol. 2019 Jan 7;9:3088. doi: 10.3389/fimmu.2018.03088. eCollection 2018.

12.

Pentraxins in Complement Activation and Regulation.

Ma YJ, Garred P.

Front Immunol. 2018 Dec 19;9:3046. doi: 10.3389/fimmu.2018.03046. eCollection 2018. Review.

13.

Expression of complement C3, C5, C3aR and C5aR1 genes in resting and activated CD4+ T cells.

Hansen CB, Willer A, Bayarri-Olmos R, Kemper C, Garred P.

Immunobiology. 2019 Mar;224(2):307-315. doi: 10.1016/j.imbio.2018.12.004. Epub 2018 Dec 27.

PMID:
30612786
14.

Targeting of Liver Mannan-Binding Lectin-Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis.

Banda NK, Desai D, Scheinman RI, Pihl R, Sekine H, Fujita T, Sharma V, Hansen AG, Garred P, Thiel S, Borodovsky A, Holers VM.

Immunohorizons. 2018 Sep;2(8):274-295. doi: 10.4049/immunohorizons.1800053.

15.

Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins.

Jürgensen HJ, Nørregaard KS, Sibree MM, Santoni-Rugiu E, Madsen DH, Wassilew K, Krustrup D, Garred P, Bugge TH, Engelholm LH, Behrendt N.

J Cell Biol. 2019 Jan 7;218(1):333-349. doi: 10.1083/jcb.201802148. Epub 2018 Oct 26.

16.

Development of a Quantitative Assay for the Characterization of Human Collectin-11 (CL-11, CL-K1).

Bayarri-Olmos R, Kirketerp-Moller N, Pérez-Alós L, Skjodt K, Skjoedt MO, Garred P.

Front Immunol. 2018 Sep 28;9:2238. doi: 10.3389/fimmu.2018.02238. eCollection 2018.

17.

Quantitative B-lymphocyte deficiency and increased TCRγδ T-lymphocytes in acute infectious spondylodiscitis.

Haugaard AK, Marquart HV, Kolte L, Ryder LP, Kehrer M, Krogstrup M, Dragsted UB, Dahl B, Gjørup IE, Andersen ÅB, Garred P, Nielsen SD.

Sci Rep. 2018 Oct 11;8(1):15174. doi: 10.1038/s41598-018-33318-w.

18.

Chimeric Proteins Containing MAP-1 and Functional Domains of C4b-Binding Protein Reveal Strong Complement Inhibitory Capacities.

Hertz CE, Bayarri-Olmos R, Kirketerp-Møller N, van Putten S, Pilely K, Skjoedt MO, Garred P.

Front Immunol. 2018 Aug 28;9:1945. doi: 10.3389/fimmu.2018.01945. eCollection 2018.

19.

Amyotrophic lateral sclerosis: The complement and inflammatory hypothesis.

Kjældgaard AL, Pilely K, Olsen KS, Pedersen SW, Lauritsen AØ, Møller K, Garred P.

Mol Immunol. 2018 Oct;102:14-25. doi: 10.1016/j.molimm.2018.06.007. Epub 2018 Jun 20. Review.

PMID:
29933890
20.

The Lectin Complement Pathway Is Involved in Protection Against Enteroaggregative Escherichia coli Infection.

Adler Sørensen C, Rosbjerg A, Hebbelstrup Jensen B, Krogfelt KA, Garred P.

Front Immunol. 2018 May 29;9:1153. doi: 10.3389/fimmu.2018.01153. eCollection 2018.

21.

Omics-Based Approach Reveals Complement-Mediated Inflammation in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS).

Blaabjerg M, Hemdrup AL, Drici L, Ruprecht K, Garred P, Höftberger R, Kristensen BW, Kondziella D, Sejbaek T, Hansen SW, Nielsen HH, Jensen P, Meyer M, Paul F, Lassmann H, Larsen MR, Illes Z.

Front Immunol. 2018 Apr 23;9:741. doi: 10.3389/fimmu.2018.00741. eCollection 2018.

22.

Persistent Intracellular Staphylococcus aureus in Keratinocytes Lead to Activation of the Complement System with Subsequent Reduction in the Intracellular Bacterial Load.

Abu-Humaidan AH, Elvén M, Sonesson A, Garred P, Sørensen OE.

Front Immunol. 2018 Mar 1;9:396. doi: 10.3389/fimmu.2018.00396. eCollection 2018.

23.

Mannose-binding lectin genotypes and outcome in end-stage renal disease: a prospective cohort study.

Adrian T, Hornum M, Eriksson F, Hansen JM, Pilely K, Garred P, Feldt-Rasmussen B.

Nephrol Dial Transplant. 2018 Nov 1;33(11):1991-1997. doi: 10.1093/ndt/gfy034.

PMID:
29514287
24.

Human brain trauma severity is associated with lectin complement pathway activation.

De Blasio D, Fumagalli S, Orsini F, Neglia L, Perego C, Ortolano F, Zanier ER, Picetti E, Locatelli M, Stocchetti N, Longhi L, Garred P, De Simoni MG.

J Cereb Blood Flow Metab. 2019 May;39(5):794-807. doi: 10.1177/0271678X18758881. Epub 2018 Feb 9.

25.

Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock.

Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE.

ESC Heart Fail. 2018 Jun;5(3):292-301. doi: 10.1002/ehf2.12266. Epub 2018 Feb 9.

26.

Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia.

Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Skattum L, Bosnes V, Garred P, Frøland SS, Mollnes TE, Aukrust P, Heggelund L.

Open Forum Infect Dis. 2018 Jan 5;5(2):ofy002. doi: 10.1093/ofid/ofy002. eCollection 2018 Feb.

27.

Preoperative methylprednisolone increases plasma Pentraxin 3 early after total knee arthroplasty: a randomized, double-blind, placebo-controlled trial.

Lindberg-Larsen V, Kehlet H, Pilely K, Bagger J, Rovsing ML, Garred P.

Clin Exp Immunol. 2018 Mar;191(3):356-362. doi: 10.1111/cei.13071. Epub 2017 Nov 9.

28.

Human stem cell-derived retinal epithelial cells activate complement via collectin 11 in response to stress.

Fanelli G, Gonzalez-Cordero A, Gardner PJ, Peng Q, Fernando M, Kloc M, Farrar CA, Naeem A, Garred P, Ali RR, Sacks SH.

Sci Rep. 2017 Nov 7;7(1):14625. doi: 10.1038/s41598-017-15212-z.

29.

Prognostic value of lectin pathway molecules and complement proteins in ascitic fluid and blood in patients with liver cirrhosis.

Glargaard S, Boysen T, Pilely K, Garred P, Ytting H.

Scand J Gastroenterol. 2018 Jan;53(1):64-69. doi: 10.1080/00365521.2017.1386710. Epub 2017 Oct 6.

PMID:
28982257
30.

C-Reactive Protein Binds to Cholesterol Crystals and Co-Localizes with the Terminal Complement Complex in Human Atherosclerotic Plaques.

Pilely K, Fumagalli S, Rosbjerg A, Genster N, Skjoedt MO, Perego C, Ferrante AMR, De Simoni MG, Garred P.

Front Immunol. 2017 Aug 29;8:1040. doi: 10.3389/fimmu.2017.01040. eCollection 2017.

31.

Associations of Plasma Nitrite, L-Arginine and Asymmetric Dimethylarginine With Morbidity and Mortality in Patients With Necrotizing Soft Tissue Infections.

Hansen MB, Rasmussen LS, Garred P, Pilely K, Wahl AM, Perner A, Madsen MB, Hedegaard ER, Simonsen U, Hyldegaard O.

Shock. 2018 Jun;49(6):667-674. doi: 10.1097/SHK.0000000000000975.

32.

Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.

Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Damås JK, Mollnes TE, Espevik T.

J Immunol. 2017 Oct 15;199(8):2910-2920. doi: 10.4049/jimmunol.1700302. Epub 2017 Aug 30.

33.

Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?

Aftab H, Christensen DL, Ambreen A, Jamil M, Garred P, Petersen JH, Nielsen SD, Bygbjerg IC.

Am J Trop Med Hyg. 2017 Oct;97(4):1099-1102. doi: 10.4269/ajtmh.16-0816. Epub 2017 Aug 18.

34.

Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo.

Genster N, Østrup O, Schjalm C, Eirik Mollnes T, Cowland JB, Garred P.

Sci Rep. 2017 Jun 20;7(1):3852. doi: 10.1038/s41598-017-04121-w.

35.

Evasion Mechanisms Used by Pathogens to Escape the Lectin Complement Pathway.

Rosbjerg A, Genster N, Pilely K, Garred P.

Front Microbiol. 2017 May 12;8:868. doi: 10.3389/fmicb.2017.00868. eCollection 2017. Review.

36.

Complement factors C4 and C3 are down regulated in response to short term overfeeding in healthy young men.

Foghmar C, Brøns C, Pilely K, Vaag A, Garred P.

Sci Rep. 2017 Apr 27;7(1):1235. doi: 10.1038/s41598-017-01382-3.

37.
38.

Inflammatory biomarkers and cancer: CRP and suPAR as markers of incident cancer in patients with serious nonspecific symptoms and signs of cancer.

Rasmussen LJH, Schultz M, Gaardsting A, Ladelund S, Garred P, Iversen K, Eugen-Olsen J, Helms M, David KP, Kjaer A, Lebech AM, Kronborg G.

Int J Cancer. 2017 Jul 1;141(1):191-199. doi: 10.1002/ijc.30732. Epub 2017 Apr 24.

39.

Lectin Pathway of Complement Activation Is Associated with Vulnerability of Atherosclerotic Plaques.

Fumagalli S, Perego C, Zangari R, De Blasio D, Oggioni M, De Nigris F, Snider F, Garred P, Ferrante AM, De Simoni MG.

Front Immunol. 2017 Mar 16;8:288. doi: 10.3389/fimmu.2017.00288. eCollection 2017.

40.

Comparative study of HbA1c and fasting plasma glucose vs the oral glucose tolerance test for diagnosis of diabetes in people with tuberculosis.

Aftab H, Ambreen A, Jamil M, Garred P, Petersen JH, Nielsen SD, Bygbjerg IC, Christensen DL.

Diabet Med. 2017 Jun;34(6):800-803. doi: 10.1111/dme.13354. Epub 2017 Apr 11.

PMID:
28326618
41.
42.

Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.

Yaseen S, Demopulos G, Dudler T, Yabuki M, Wood CL, Cummings WJ, Tjoelker LW, Fujita T, Sacks S, Garred P, Andrew P, Sim RB, Lachmann PJ, Wallis R, Lynch N, Schwaeble WJ.

FASEB J. 2017 May;31(5):2210-2219. doi: 10.1096/fj.201601306R. Epub 2017 Feb 10.

PMID:
28188176
43.

Association between cytokine response, the LRINEC score and outcome in patients with necrotising soft tissue infection: a multicentre, prospective study.

Hansen MB, Rasmussen LS, Svensson M, Chakrakodi B, Bruun T, Madsen MB, Perner A, Garred P, Hyldegaard O, Norrby-Teglund A; INFECT study group.

Sci Rep. 2017 Feb 8;7:42179. doi: 10.1038/srep42179.

44.

High prevalence of diabetes and anthropometric heterogeneity among tuberculosis patients in Pakistan.

Aftab H, Ambreen A, Jamil M, Garred P, Petersen JH, Nielsen SD, Bygbjerg IC, Christensen DL.

Trop Med Int Health. 2017 Apr;22(4):465-473. doi: 10.1111/tmi.12842. Epub 2017 Feb 23.

45.

Association of ficolin-3 with abdominal aortic aneurysm presence and progression.

Fernandez-García CE, Burillo E, Lindholt JS, Martinez-Lopez D, Pilely K, Mazzeo C, Michel JB, Egido J, Garred P, Blanco-Colio LM, Martin-Ventura JL.

J Thromb Haemost. 2017 Mar;15(3):575-585. doi: 10.1111/jth.13608. Epub 2017 Feb 15.

46.

Plasma ficolin levels and risk of nephritis in Danish patients with systemic lupus erythematosus.

Tanha N, Pilely K, Faurschou M, Garred P, Jacobsen S.

Clin Rheumatol. 2017 Feb;36(2):335-341. doi: 10.1007/s10067-016-3508-2. Epub 2016 Dec 15.

PMID:
27981461
47.

Complementary Roles of the Classical and Lectin Complement Pathways in the Defense against Aspergillus fumigatus.

Rosbjerg A, Genster N, Pilely K, Skjoedt MO, Stahl GL, Garred P.

Front Immunol. 2016 Nov 3;7:473. eCollection 2016.

48.

Ficolins Promote Fungal Clearance in vivo and Modulate the Inflammatory Cytokine Response in Host Defense against Aspergillus fumigatus.

Genster N, Præstekjær Cramer E, Rosbjerg A, Pilely K, Cowland JB, Garred P.

J Innate Immun. 2016;8(6):579-588. Epub 2016 Jul 29.

49.

A journey through the lectin pathway of complement-MBL and beyond.

Garred P, Genster N, Pilely K, Bayarri-Olmos R, Rosbjerg A, Ma YJ, Skjoedt MO.

Immunol Rev. 2016 Nov;274(1):74-97. doi: 10.1111/imr.12468. Review.

PMID:
27782323
50.

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation.

Ekdahl KN, Teramura Y, Hamad OA, Asif S, Duehrkop C, Fromell K, Gustafson E, Hong J, Kozarcanin H, Magnusson PU, Huber-Lang M, Garred P, Nilsson B.

Immunol Rev. 2016 Nov;274(1):245-269. doi: 10.1111/imr.12471. Review.

PMID:
27782319

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