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Items: 1 to 50 of 260

1.

Erratum to: Drug Sensitivity Assays of Human Cancer Organoid Cultures.

Francies HE, Barthorpe A, McLaren-Douglas A, Barendt WJ, Garnett MJ.

Methods Mol Biol. 2018 Mar 27. doi: 10.1007/7651_2018_138. [Epub ahead of print] No abstract available.

PMID:
30006863
2.

Enhanced nanoparticle uptake into virus infected cells: Could nanoparticles be useful in antiviral therapy?

Abo-Zeid Y, Urbanowicz RA, Thomson BJ, Irving WL, Tarr AW, Garnett MC.

Int J Pharm. 2018 Jun 13;547(1-2):572-581. doi: 10.1016/j.ijpharm.2018.06.027. [Epub ahead of print]

PMID:
29908332
3.

Itraconazole targets cell cycle heterogeneity in colorectal cancer.

Buczacki SJA, Popova S, Biggs E, Koukorava C, Buzzelli J, Vermeulen L, Hazelwood L, Francies H, Garnett MJ, Winton DJ.

J Exp Med. 2018 Jul 2;215(7):1891-1912. doi: 10.1084/jem.20171385. Epub 2018 May 31.

4.

Discrete taxa of saprotrophic fungi respire different ages of carbon from Antarctic soils.

Newsham KK, Garnett MH, Robinson CH, Cox F.

Sci Rep. 2018 May 18;8(1):7866. doi: 10.1038/s41598-018-25877-9.

5.

Rux largely restores lungs in Iraq PM-exposed mice, Up-regulating regulatory T-cells (Tregs).

Lin D, Li J, Razi R, Qamar N, Levine L, Zimmerman T, Hamidi SA, Schmidt M, Golightly MG, Rueb T, Harrington A, Garnett M, Antonawich F, McClain S, Miller E, Cox C, Huang PH, Szema AM.

Exp Lung Res. 2018 Apr;44(3):153-166. doi: 10.1080/01902148.2018.1459957. Epub 2018 May 8.

PMID:
29737931
6.

The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils.

Stammnitz MR, Coorens THH, Gori KC, Hayes D, Fu B, Wang J, Martin-Herranz DE, Alexandrov LB, Baez-Ortega A, Barthorpe S, Beck A, Giordano F, Knowles GW, Kwon YM, Hall G, Price S, Pye RJ, Tubio JMC, Siddle HVT, Sohal SS, Woods GM, McDermott U, Yang F, Garnett MJ, Ning Z, Murchison EP.

Cancer Cell. 2018 Apr 9;33(4):607-619.e15. doi: 10.1016/j.ccell.2018.03.013.

7.

Synthesis and properties of a biodegradable polymer-drug conjugate: Methotrexate-poly(glycerol adipate).

Suksiriworapong J, Taresco V, Ivanov DP, Styliari ID, Sakchaisri K, Junyaprasert VB, Garnett MC.

Colloids Surf B Biointerfaces. 2018 Jul 1;167:115-125. doi: 10.1016/j.colsurfb.2018.03.048. Epub 2018 Mar 28.

PMID:
29631222
8.

Vascular plant-mediated controls on atmospheric carbon assimilation and peat carbon decomposition under climate change.

Gavazov K, Albrecht R, Buttler A, Dorrepaal E, Garnett MH, Gogo S, Hagedorn F, Mills RTE, Robroek BJM, Bragazza L.

Glob Chang Biol. 2018 Mar 23. doi: 10.1111/gcb.14140. [Epub ahead of print]

PMID:
29569798
9.

Cerebral autoregulation, cerebrospinal fluid outflow resistance, and outcome following cerebrospinal fluid diversion in normal pressure hydrocephalus.

Lalou AD, Czosnyka M, Donnelly J, Pickard JD, FMedSci, Nabbanja E, Keong NC, Garnett M, Czosnyka ZH.

J Neurosurg. 2018 Mar 16:1-9. doi: 10.3171/2017.7.JNS17216. [Epub ahead of print]

PMID:
29547089
10.

Water Solubility Enhancement of Pyrazolo[3,4-d]pyrimidine Derivatives via Miniaturized Polymer-Drug Microarrays.

Sanna M, Sicilia G, Alazzo A, Singh N, Musumeci F, Schenone S, Spriggs KA, Burley JC, Garnett MC, Taresco V, Alexander C.

ACS Med Chem Lett. 2018 Jan 29;9(3):193-197. doi: 10.1021/acsmedchemlett.7b00456. eCollection 2018 Mar 8.

PMID:
29541359
11.

Radiological Correlates of Raised Intracranial Pressure in Children: A Review.

Kayhanian S, Young AMH, Piper RJ, Donnelly J, Scoffings D, Garnett MR, Fernandes HM, Smielewski P, Czosnyka M, Hutchinson PJ, Agrawal S.

Front Pediatr. 2018 Feb 23;6:32. doi: 10.3389/fped.2018.00032. eCollection 2018. Review.

12.

Validation of Davson's equation in patients suffering from idiopathic normal pressure hydrocephalus.

Lalou AD, Levrini V, Garnett M, Nabbanja E, Kim DJ, Gergele L, Bjornson A, Czosnyka Z, Czosnyka M.

Acta Neurochir (Wien). 2018 May;160(5):1097-1103. doi: 10.1007/s00701-018-3497-9. Epub 2018 Mar 8.

PMID:
29520439
13.

Comparison of Gene Transfection and Cytotoxicity Mechanisms of Linear Poly(amidoamine) and Branched Poly(ethyleneimine) Polyplexes.

Almulathanon AAY, Ranucci E, Ferruti P, Garnett MC, Bosquillon C.

Pharm Res. 2018 Mar 7;35(4):86. doi: 10.1007/s11095-017-2328-7.

PMID:
29516282
14.

MicroRNA-Based Drugs for Brain Tumors.

Anthiya S, Griveau A, Loussouarn C, Baril P, Garnett M, Issartel JP, Garcion E.

Trends Cancer. 2018 Mar;4(3):222-238. doi: 10.1016/j.trecan.2017.12.008. Epub 2018 Feb 9. Review.

PMID:
29506672
15.

Is There a Link Between ICP-Derived Infusion Test Parameters and Outcome After Shunting in Normal Pressure Hydrocephalus?

Nabbanja E, Czosnyka M, Keong NC, Garnett M, Pickard JD, Lalou DA, Czosnyka Z.

Acta Neurochir Suppl. 2018;126:229-232. doi: 10.1007/978-3-319-65798-1_46.

PMID:
29492566
16.

Are Slow Waves of Intracranial Pressure Suppressed by General Anaesthesia?

Lalou DA, Czosnyka M, Donnelly J, Lavinio A, Pickard JD, Garnett M, Czosnyka Z.

Acta Neurochir Suppl. 2018;126:129-132. doi: 10.1007/978-3-319-65798-1_27.

PMID:
29492547
17.

Computed Tomography Indicators of Deranged Intracranial Physiology in Paediatric Traumatic Brain Injury.

Young AMH, Donnelly J, Liu X, Guilfoyle MR, Carew M, Cabeleira M, Cardim D, Garnett MR, Fernandes HM, Haubrich C, Smielewski P, Czosnyka M, Hutchinson PJ, Agrawal S.

Acta Neurochir Suppl. 2018;126:29-34. doi: 10.1007/978-3-319-65798-1_7.

PMID:
29492527
18.

Pre-hospital Predictors of Impaired ICP Trends in Continuous Monitoring of Paediatric Traumatic Brain Injury Patients.

Young AMH, Donnelly J, Liu X, Guilfoyle MR, Carew M, Cabeleira M, Cardim D, Garnett MR, Fernandes HM, Haubrich C, Smielewski P, Czosnyka M, Hutchinson PJ, Agrawal S.

Acta Neurochir Suppl. 2018;126:7-10. doi: 10.1007/978-3-319-65798-1_2.

PMID:
29492522
19.

Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer.

Unbekandt M, Belshaw S, Bower J, Clarke M, Cordes J, Crighton D, Croft DR, Drysdale MJ, Garnett MJ, Gill K, Gray C, Greenhalgh DA, Hall JAM, Konczal J, Lilla S, McArthur D, McConnell P, McDonald L, McGarry L, McKinnon H, McMenemy C, Mezna M, Morrice NA, Munro J, Naylor G, Rath N, Schüttelkopf AW, Sime M, Olson MF.

Cancer Res. 2018 Apr 15;78(8):2096-2114. doi: 10.1158/0008-5472.CAN-17-2870. Epub 2018 Jan 30.

PMID:
29382705
20.

Intermolecular interaction and solid state characterization of abietic acid/chitosan solid dispersions possessing antimicrobial and antioxidant properties.

Cuzzucoli Crucitti V, Migneco LM, Piozzi A, Taresco V, Garnett M, Argent RH, Francolini I.

Eur J Pharm Biopharm. 2018 Apr;125:114-123. doi: 10.1016/j.ejpb.2018.01.012. Epub 2018 Jan 31.

PMID:
29366926
21.

Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells.

Kolluri KK, Alifrangis C, Kumar N, Ishii Y, Price S, Michaut M, Williams S, Barthorpe S, Lightfoot H, Busacca S, Sharkey A, Yuan Z, Sage EK, Vallath S, Le Quesne J, Tice DA, Alrifai D, von Karstedt S, Montinaro A, Guppy N, Waller DA, Nakas A, Good R, Holmes A, Walczak H, Fennell DA, Garnett M, Iorio F, Wessels L, McDermott U, Janes SM.

Elife. 2018 Jan 18;7. pii: e30224. doi: 10.7554/eLife.30224.

22.

Perturbation-response genes reveal signaling footprints in cancer gene expression.

Schubert M, Klinger B, Klünemann M, Sieber A, Uhlitz F, Sauer S, Garnett MJ, Blüthgen N, Saez-Rodriguez J.

Nat Commun. 2018 Jan 2;9(1):20. doi: 10.1038/s41467-017-02391-6.

23.

Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer.

Garcia-Alonso L, Iorio F, Matchan A, Fonseca N, Jaaks P, Peat G, Pignatelli M, Falcone F, Benes CH, Dunham I, Bignell G, McDade SS, Garnett MJ, Saez-Rodriguez J.

Cancer Res. 2018 Feb 1;78(3):769-780. doi: 10.1158/0008-5472.CAN-17-1679. Epub 2017 Dec 11.

PMID:
29229604
24.

Corrigendum: Glycemia Is Related to Impaired Cerebrovascular Autoregulation after Severe Pediatric Traumatic Brain Injury: A Retrospective Observational Study.

Young AMH, Adams H, Donnelly J, Guilfoyle MR, Fernandes H, Garnett MR, Czosnyka M, Smielewski P, Plummer M, Agrawal S, Hutchinson PJ.

Front Pediatr. 2017 Nov 24;5:245. doi: 10.3389/fped.2017.00245. eCollection 2017.

25.

GDSCTools for mining pharmacogenomic interactions in cancer.

Cokelaer T, Chen E, Iorio F, Menden MP, Lightfoot H, Saez-Rodriguez J, Garnett MJ.

Bioinformatics. 2018 Apr 1;34(7):1226-1228. doi: 10.1093/bioinformatics/btx744.

26.

Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies.

Prabhu VV, Talekar MK, Lulla AR, Kline CLB, Zhou L, Hall J, Van den Heuvel APJ, Dicker DT, Babar J, Grupp SA, Garnett MJ, McDermott U, Benes CH, Pu JJ, Claxton DF, Khan N, Oster W, Allen JE, El-Deiry WS.

Cell Cycle. 2018;17(4):468-478. doi: 10.1080/15384101.2017.1403689. Epub 2018 Feb 19.

PMID:
29157092
27.

Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.

Broutier L, Mastrogiovanni G, Verstegen MM, Francies HE, Gavarró LM, Bradshaw CR, Allen GE, Arnes-Benito R, Sidorova O, Gaspersz MP, Georgakopoulos N, Koo BK, Dietmann S, Davies SE, Praseedom RK, Lieshout R, IJzermans JNM, Wigmore SJ, Saeb-Parsy K, Garnett MJ, van der Laan LJ, Huch M.

Nat Med. 2017 Dec;23(12):1424-1435. doi: 10.1038/nm.4438. Epub 2017 Nov 13.

28.

Comprehensive Pharmacogenomic Profiling of Malignant Pleural Mesothelioma Identifies a Subgroup Sensitive to FGFR Inhibition.

Quispel-Janssen JM, Badhai J, Schunselaar L, Price S, Brammeld J, Iorio F, Kolluri K, Garnett M, Berns A, Baas P, McDermott U, Neefjes J, Alifrangis C.

Clin Cancer Res. 2018 Jan 1;24(1):84-94. doi: 10.1158/1078-0432.CCR-17-1172. Epub 2017 Oct 23.

PMID:
29061644
29.

Profiling Autism Symptomatology: An Exploration of the Q-ASC Parental Report Scale in Capturing Sex Differences in Autism.

Ormond S, Brownlow C, Garnett MS, Rynkiewicz A, Attwood T.

J Autism Dev Disord. 2018 Feb;48(2):389-403. doi: 10.1007/s10803-017-3324-9.

PMID:
29052806
30.

Glycemia Is Related to Impaired Cerebrovascular Autoregulation after Severe Pediatric Traumatic Brain Injury: A Retrospective Observational Study.

Young AMH, Adams H, Donnelly J, Guilfoyle MR, Fernandes H, Garnett MR, Czosnyka M, Smielewski P, Plummer M, Agrawal S, Hutchinson PJ.

Front Pediatr. 2017 Sep 25;5:205. doi: 10.3389/fped.2017.00205. eCollection 2017. Erratum in: Front Pediatr. 2017 Nov 24;5:245.

31.

High-throughput RNAi screen for essential genes and drug synergistic combinations in colorectal cancer.

Williams SP, Barthorpe AS, Lightfoot H, Garnett MJ, McDermott U.

Sci Data. 2017 Oct 3;4:170139. doi: 10.1038/sdata.2017.139.

32.

Limited awareness of pre-exposure prophylaxis among black men who have sex with men and transgender women in New York city.

Garnett M, Hirsch-Moverman Y, Franks J, Hayes-Larson E, El-Sadr WM, Mannheimer S.

AIDS Care. 2018 Jan;30(1):9-17. doi: 10.1080/09540121.2017.1363364. Epub 2017 Aug 9.

PMID:
28791876
33.

Properties of acyl modified poly(glycerol-adipate) comb-like polymers and their self-assembly into nanoparticles.

Taresco V, Suksiriworapong J, Creasey R, Burley JC, Mantovani G, Alexander C, Treacher K, Booth J, Garnett MC.

J Polym Sci A Polym Chem. 2016 Oct 15;54(20):3267-3278. doi: 10.1002/pola.28215. Epub 2016 Jul 8.

34.

Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.

Prabhu VV, Lulla AR, Madhukar NS, Ralff MD, Zhao D, Kline CLB, Van den Heuvel APJ, Lev A, Garnett MJ, McDermott U, Benes CH, Batchelor TT, Chi AS, Elemento O, Allen JE, El-Deiry WS.

PLoS One. 2017 Aug 2;12(8):e0180541. doi: 10.1371/journal.pone.0180541. eCollection 2017.

35.

Aquatic export of young dissolved and gaseous carbon from a pristine boreal fen: Implications for peat carbon stock stability.

Campeau A, Bishop KH, Billett MF, Garnett MH, Laudon H, Leach JA, Nilsson MB, Öquist MG, Wallin MB.

Glob Chang Biol. 2017 Dec;23(12):5523-5536. doi: 10.1111/gcb.13815. Epub 2017 Sep 1.

PMID:
28712133
36.

Magnetic Resonance Imaging Quantification of Fasted State Colonic Liquid Pockets in Healthy Humans.

Murray K, Hoad CL, Mudie DM, Wright J, Heissam K, Abrehart N, Pritchard SE, Al Atwah S, Gowland PA, Garnett MC, Amidon GE, Spiller RC, Amidon GL, Marciani L.

Mol Pharm. 2017 Aug 7;14(8):2629-2638. doi: 10.1021/acs.molpharmaceut.7b00095. Epub 2017 Jul 6.

37.

Rapid Nanogram Scale Screening Method of Microarrays to Evaluate Drug-Polymer Blends Using High-Throughput Printing Technology.

Taresco V, Louzao I, Scurr D, Booth J, Treacher K, McCabe J, Turpin E, Laughton CA, Alexander C, Burley JC, Garnett MC.

Mol Pharm. 2017 Jun 5;14(6):2079-2087. doi: 10.1021/acs.molpharmaceut.7b00182. Epub 2017 May 19.

PMID:
28502181
38.

Revisiting olfactory receptors as putative drivers of cancer.

Ranzani M, Iyer V, Ibarra-Soria X, Del Castillo Velasco-Herrera M, Garnett M, Logan D, Adams DJ.

Wellcome Open Res. 2017 Feb 10;2:9. doi: 10.12688/wellcomeopenres.10646.1.

39.

High-Throughput Spheroid Screens Using Volume, Resazurin Reduction, and Acid Phosphatase Activity.

Ivanov DP, Grabowska AM, Garnett MC.

Methods Mol Biol. 2017;1601:43-59. doi: 10.1007/978-1-4939-6960-9_4.

PMID:
28470516
40.

A Road Map for Precision Cancer Medicine Using Personalized Models.

Picco G, Garnett MJ.

Cancer Discov. 2017 May;7(5):456-458. doi: 10.1158/2159-8290.CD-17-0268.

41.

Drug Resistance Mechanisms in Colorectal Cancer Dissected with Cell Type-Specific Dynamic Logic Models.

Eduati F, Doldàn-Martelli V, Klinger B, Cokelaer T, Sieber A, Kogera F, Dorel M, Garnett MJ, Blüthgen N, Saez-Rodriguez J.

Cancer Res. 2017 Jun 15;77(12):3364-3375. doi: 10.1158/0008-5472.CAN-17-0078. Epub 2017 Apr 5.

42.

An Evaluation of Styloidectomy as an Adjunct or Alternative to Jugular Stenting in Idiopathic Intracranial Hypertension and Disturbances of Cranial Venous Outflow.

Higgins JN, Garnett MR, Pickard JD, Axon PR.

J Neurol Surg B Skull Base. 2017 Apr;78(2):158-163. doi: 10.1055/s-0036-1594238. Epub 2016 Nov 23.

43.

Ancient dissolved methane in inland waters revealed by a new collection method at low field concentrations for radiocarbon (14C) analysis.

Dean JF, Billett MF, Murray C, Garnett MH.

Water Res. 2017 May 15;115:236-244. doi: 10.1016/j.watres.2017.03.009. Epub 2017 Mar 6.

44.

Late Administration of a Palladium Lipoic Acid Complex (POLY-MVA) Modifies Cardiac Mitochondria but Not Functional or Structural Manifestations of Radiation-Induced Heart Disease in a Rat Model.

Sridharan V, Seawright JW, Antonawich FJ, Garnett M, Cao M, Singh P, Boerma M.

Radiat Res. 2017 Mar;187(3):361-366. doi: 10.1667/RR14643.1. Epub 2017 Feb 23.

45.

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Brammeld JS, Petljak M, Martincorena I, Williams SP, Alonso LG, Dalmases A, Bellosillo B, Robles-Espinoza CD, Price S, Barthorpe S, Tarpey P, Alifrangis C, Bignell G, Vidal J, Young J, Stebbings L, Beal K, Stratton MR, Saez-Rodriguez J, Garnett M, Montagut C, Iorio F, McDermott U.

Genome Res. 2017 Apr;27(4):613-625. doi: 10.1101/gr.213546.116. Epub 2017 Feb 8.

46.

Impact of intravenous infusion time on AAV8 vector pharmacokinetics, safety, and liver transduction in cynomolgus macaques.

Greig JA, Nordin JM, Bote E, Makaron L, Garnett ME, Kattenhorn LM, Bell P, Goode T, Wilson JM.

Mol Ther Methods Clin Dev. 2016 Dec 7;3:16079. eCollection 2016.

47.

Isolated oculomotor nerve palsy in patients with mild head injury.

Tajsic T, Kolias AG, Das T, Scoffings D, Muthusamy B, Garnett MR, Hutchinson PJ.

Br J Neurosurg. 2017 Feb;31(1):94-95. doi: 10.1080/02688697.2016.1265093. Epub 2016 Dec 7.

PMID:
27927015
48.

Can the Arts Get Under the Skin? Arts and Cortisol for Economically Disadvantaged Children.

Brown ED, Garnett ML, Anderson KE, Laurenceau JP.

Child Dev. 2017 Jul;88(4):1368-1381. doi: 10.1111/cdev.12652. Epub 2016 Dec 6.

PMID:
27921313
49.

Logic models to predict continuous outputs based on binary inputs with an application to personalized cancer therapy.

Knijnenburg TA, Klau GW, Iorio F, Garnett MJ, McDermott U, Shmulevich I, Wessels LF.

Sci Rep. 2016 Nov 23;6:36812. doi: 10.1038/srep36812.

50.

The application of adult traumatic brain injury models in a pediatric cohort.

Young AM, Guilfoyle MR, Fernandes H, Garnett MR, Agrawal S, Hutchinson PJ.

J Neurosurg Pediatr. 2016 Nov;18(5):558-564. Epub 2016 Aug 26.

PMID:
27564785

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