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Items: 1 to 50 of 201

1.

Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure.

Lombardi M, Parolisi R, Scaroni F, Bonfanti E, Gualerzi A, Gabrielli M, Kerlero de Rosbo N, Uccelli A, Giussani P, Viani P, Garlanda C, Abbracchio MP, Chaabane L, Buffo A, Fumagalli M, Verderio C.

Acta Neuropathol. 2019 Jul 30. doi: 10.1007/s00401-019-02049-1. [Epub ahead of print]

PMID:
31363836
2.

TLR3 preconditioning induces anti-inflammatory and anti-ictogenic effects in mice mediated by the IRF3/IFN-β axis.

Kostoula C, Shaker T, Cerovic M, Craparotta I, Marchini S, Butti E, Pascente R, Iori V, Garlanda C, Aronica E, Martino G, Ravizza T, Carmant L, Vezzani A.

Brain Behav Immun. 2019 Jul 20. pii: S0889-1591(19)30429-5. doi: 10.1016/j.bbi.2019.07.021. [Epub ahead of print]

PMID:
31336144
3.

Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors.

Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, Magrini E, Gianni F, Kunderfranco P, Polentarutti N, Pasqualini F, Di Marco S, Supino D, Peano C, Cananzi F, Colombo P, Pilotti S, Alomar SY, Bonavita E, Galdiero MR, Garlanda C, Mantovani A, Jaillon S.

Cell. 2019 Jul 11;178(2):346-360.e24. doi: 10.1016/j.cell.2019.05.047. Epub 2019 Jun 27.

4.

The Long Pentraxin PTX3 as a Humoral Innate Immunity Functional Player and Biomarker of Infections and Sepsis.

Porte R, Davoudian S, Asgari F, Parente R, Mantovani A, Garlanda C, Bottazzi B.

Front Immunol. 2019 Apr 12;10:794. doi: 10.3389/fimmu.2019.00794. eCollection 2019. Review.

5.

The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer.

Doni A, Stravalaci M, Inforzato A, Magrini E, Mantovani A, Garlanda C, Bottazzi B.

Front Immunol. 2019 Apr 4;10:712. doi: 10.3389/fimmu.2019.00712. eCollection 2019. Review.

6.

IL1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development.

Riva F, Ponzoni M, Supino D, Bertilaccio MTS, Polentarutti N, Massara M, Pasqualini F, Carriero R, Innocenzi A, Anselmo A, Veliz-Rodriguez T, Simonetti G, Anders HJ, Caligaris-Cappio F, Mantovani A, Muzio M, Garlanda C.

Cancer Immunol Res. 2019 Jun;7(6):874-885. doi: 10.1158/2326-6066.CIR-18-0698. Epub 2019 Apr 24.

PMID:
31018956
7.

Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity.

Mantovani A, Dinarello CA, Molgora M, Garlanda C.

Immunity. 2019 Apr 16;50(4):778-795. doi: 10.1016/j.immuni.2019.03.012. Review.

PMID:
30995499
8.

Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity.

Bonacina F, Moregola A, Porte R, Baragetti A, Bonavita E, Salatin A, Grigore L, Pellegatta F, Molgora M, Sironi M, Barbati E, Mantovani A, Bottazzi B, Catapano AL, Garlanda C, Norata GD.

Cardiovasc Res. 2019 Mar 12. pii: cvz068. doi: 10.1093/cvr/cvz068. [Epub ahead of print]

PMID:
30859179
9.

The Long Pentraxin 3 Contributes to Joint Inflammation in Gout by Facilitating the Phagocytosis of Monosodium Urate Crystals.

Batista NV, Barbagallo M, Oliveira VLS, Castro-Gomes T, Oliveira RDR, Louzada-Junior P, Pinheiro GRC, Mantovani A, Teixeira MM, Garlanda C, Amaral FA.

J Immunol. 2019 Mar 15;202(6):1807-1814. doi: 10.4049/jimmunol.1701531. Epub 2019 Feb 4.

PMID:
30718300
10.

Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection.

Ciancarella V, Lembo-Fazio L, Paciello I, Bruno AK, Jaillon S, Berardi S, Barbagallo M, Meron-Sudai S, Cohen D, Molinaro A, Rossi G, Garlanda C, Bernardini ML.

PLoS Pathog. 2018 Dec 7;14(12):e1007469. doi: 10.1371/journal.ppat.1007469. eCollection 2018 Dec.

11.

Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin.

Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, Ghirardini E, Filipello F, Moretti M, Gotti C, Annis DS, Mosher DF, Garlanda C, Bottazzi B, Taraboletti G, Mantovani A, Matteoli M, Menna E.

EMBO J. 2019 Jan 3;38(1). pii: e99529. doi: 10.15252/embj.201899529. Epub 2018 Nov 5.

12.

Corrigendum to "Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation" [Biochim. Biophys. Acta, 1862 (2016) 1182-1190].

Bonacina F, Barbieri SS, Cutuli L, Amadi P, Don A, Sironi M, Tartari S, Mantovani A, Bottazzi B, Garlanda C, Tremoli E, Catapano AL, Norata GD.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):262. doi: 10.1016/j.bbadis.2018.09.017. Epub 2018 Oct 16. No abstract available.

PMID:
30340914
13.

The Long Pentraxin PTX3 Is an Endogenous Inhibitor of Hyperoxaluria-Related Nephrocalcinosis and Chronic Kidney Disease.

Marschner JA, Mulay SR, Steiger S, Anguiano L, Zhao Z, Boor P, Rahimi K, Inforzato A, Garlanda C, Mantovani A, Anders HJ.

Front Immunol. 2018 Sep 25;9:2173. doi: 10.3389/fimmu.2018.02173. eCollection 2018.

14.

Pentraxin 3 promotes long-term cerebral blood flow recovery, angiogenesis, and neuronal survival after stroke.

Rajkovic I, Wong R, Lemarchand E, Rivers-Auty J, Rajkovic O, Garlanda C, Allan SM, Pinteaux E.

J Mol Med (Berl). 2018 Dec;96(12):1319-1332. doi: 10.1007/s00109-018-1698-6. Epub 2018 Oct 13.

15.

Optical in vivo imaging detection of preclinical models of gut tumors through the expression of integrin αVβ3.

Marelli G, Avigni R, Allavena P, Garlanda C, Mantovani A, Doni A, Erreni M.

Oncotarget. 2018 Jul 31;9(59):31380-31396. doi: 10.18632/oncotarget.25826. eCollection 2018 Jul 31.

16.

The yin-yang of the interaction between myelomonocytic cells and NK cells.

Molgora M, Supino D, Mavilio D, Santoni A, Moretta L, Mantovani A, Garlanda C.

Scand J Immunol. 2018 Sep;88(3):e12705. doi: 10.1111/sji.12705. Epub 2018 Aug 19. Review.

17.

PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer.

Garlanda C, Bottazzi B, Magrini E, Inforzato A, Mantovani A.

Physiol Rev. 2018 Apr 1;98(2):623-639. doi: 10.1152/physrev.00016.2017.

18.

IL-1 and IL-1 regulatory pathways in cancer progression and therapy.

Mantovani A, Barajon I, Garlanda C.

Immunol Rev. 2018 Jan;281(1):57-61. doi: 10.1111/imr.12614. Review.

19.

Tuning inflammation and immunity by the negative regulators IL-1R2 and IL-1R8.

Molgora M, Supino D, Mantovani A, Garlanda C.

Immunol Rev. 2018 Jan;281(1):233-247. doi: 10.1111/imr.12609. Review.

20.

IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity.

Molgora M, Bonavita E, Ponzetta A, Riva F, Barbagallo M, Jaillon S, Popović B, Bernardini G, Magrini E, Gianni F, Zelenay S, Jonjić S, Santoni A, Garlanda C, Mantovani A.

Nature. 2017 Nov 2;551(7678):110-114. doi: 10.1038/nature24293. Epub 2017 Oct 25.

21.

The long pentraxin PTX3: A prototypical sensor of tissue injury and a regulator of homeostasis.

Erreni M, Manfredi AA, Garlanda C, Mantovani A, Rovere-Querini P.

Immunol Rev. 2017 Nov;280(1):112-125. doi: 10.1111/imr.12570. Review.

PMID:
29027216
22.

Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.

Cavalli G, Koenders M, Kalabokis V, Kim J, Choon Tan A, Garlanda C, Mantovani A, Dagna L, Joosten LAB, Dinarello CA.

Rheumatology (Oxford). 2017 Dec 1;56(12):2256. doi: 10.1093/rheumatology/kex348. No abstract available.

23.

Pro-inflammatory M1/Th1 type immune network and increased expression of TSG-6 in the eutopic endometrium from women with endometriosis.

Matteo M, Cicinelli E, Neri M, Carrubba R, Carpagnano FA, Romeo F, Scutiero G, Greco P, Garlanda C, Vendemiale G, Levi Setti PE, Serviddio G.

Eur J Obstet Gynecol Reprod Biol. 2017 Nov;218:99-105. doi: 10.1016/j.ejogrb.2017.08.014. Epub 2017 Sep 7.

PMID:
28963923
24.

Sexual Dimorphism in Innate Immunity.

Jaillon S, Berthenet K, Garlanda C.

Clin Rev Allergy Immunol. 2019 Jun;56(3):308-321. doi: 10.1007/s12016-017-8648-x. Review.

PMID:
28963611
25.

Epigenetic regulation of the extrinsic oncosuppressor PTX3 gene in inflammation and cancer.

Rubino M, Kunderfranco P, Basso G, Greco CM, Pasqualini F, Serio S, Roncalli M, Laghi L, Mantovani A, Papait R, Garlanda C.

Oncoimmunology. 2017 May 30;6(7):e1333215. doi: 10.1080/2162402X.2017.1333215. eCollection 2017.

26.

High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity.

Campesato LF, Silva APM, Cordeiro L, Correa BR, Navarro FCP, Zanin RF, Marçola M, Inoue LT, Duarte ML, Molgora M, Pasqualini F, Massara M, Galante P, Barroso-Sousa R, Polentarutti N, Riva F, Costa ET, Mantovani A, Garlanda C, Camargo AA.

Oncotarget. 2017 Jul 25;8(30):49470-49483. doi: 10.18632/oncotarget.17713.

27.

Correction: The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells.

Chorny A, Casas-Recasens S, Sintes J, Shan M, Polentarutti N, García-Escudero R, Walland AC, Yeiser JR, Cassis L, Carrillo J, Puga I, Cunha C, Bastos H, Rodrigues F, Lacerda JF, Morais A, Dieguez-Gonzalez R, Heeger PS, Salvatori G, Carvalho A, Garcia-Sastre A, Blander JM, Mantovani A, Garlanda C, Cerutti A.

J Exp Med. 2017 May 1;214(5):1559. doi: 10.1084/jem.2015028204172017c. Epub 2017 Apr 18. No abstract available.

28.

Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects.

Tomasoni R, Morini R, Lopez-Atalaya JP, Corradini I, Canzi A, Rasile M, Mantovani C, Pozzi D, Garlanda C, Mantovani A, Menna E, Barco A, Matteoli M.

Elife. 2017 Mar 28;6. pii: e21735. doi: 10.7554/eLife.21735.

29.

Intraperitoneal adoptive transfer of mesenchymal stem cells enhances recovery from acid aspiration acute lung injury in mice.

Mauri T, Zambelli V, Cappuzzello C, Bellani G, Dander E, Sironi M, Castiglioni V, Doni A, Mantovani A, Biondi A, Garlanda C, D'amico G, Pesenti A.

Intensive Care Med Exp. 2017 Dec;5(1):13. doi: 10.1186/s40635-017-0126-5. Epub 2017 Mar 6.

30.

Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance.

Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, Dinarello CA.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2313-2318. doi: 10.1073/pnas.1619011114. Epub 2017 Feb 13.

31.

Interplay between Myeloid Cells and Humoral Innate Immunity.

Jaillon S, Bonavita E, Garlanda C, Mantovani A.

Microbiol Spectr. 2016 Dec;4(6). doi: 10.1128/microbiolspec.MCHD-0051-2016. Review.

PMID:
28087941
32.

The clearance of cell remnants and the regeneration of the injured muscle depend on soluble pattern recognition receptor PTX3.

Vezzoli M, Sciorati C, Campana L, Monno A, Doglio MG, Rigamonti E, Corna G, Touvier T, Castiglioni A, Capobianco A, Mantovani A, Manfredi AA, Garlanda C, Rovere-Querini P.

Mol Med. 2017 Jan;22:809-820. doi: 10.2119/molmed.2016.00002. Epub 2016 Nov 23.

33.

Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation.

Dander E, De Lorenzo P, Bottazzi B, Quarello P, Vinci P, Balduzzi A, Masciocchi F, Bonanomi S, Cappuzzello C, Prunotto G, Pavan F, Pasqualini F, Sironi M, Cuccovillo I, Leone R, Salvatori G, Parma M, Terruzzi E, Pagni F, Locatelli F, Mantovani A, Fagioli F, Biondi A, Garlanda C, Valsecchi MG, Rovelli A, D'Amico G.

Oncotarget. 2016 Dec 13;7(50):82123-82138. doi: 10.18632/oncotarget.13488.

34.

Innate immunity, hemostasis and matrix remodeling: PTX3 as a link.

Doni A, Garlanda C, Mantovani A.

Semin Immunol. 2016 Dec;28(6):570-577. doi: 10.1016/j.smim.2016.10.012. Epub 2016 Nov 20. Review.

35.

Pentraxins in the activation and regulation of innate immunity.

Daigo K, Inforzato A, Barajon I, Garlanda C, Bottazzi B, Meri S, Mantovani A.

Immunol Rev. 2016 Nov;274(1):202-217. doi: 10.1111/imr.12476. Review.

36.

Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation.

Wang L, Cano M, Datta S, Wei H, Ebrahimi KB, Gorashi Y, Garlanda C, Handa JT.

J Pathol. 2016 Dec;240(4):495-506. doi: 10.1002/path.4811.

PMID:
27659908
37.

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells.

Chorny A, Casas-Recasens S, Sintes J, Shan M, Polentarutti N, García-Escudero R, Walland AC, Yeiser JR, Cassis L, Carrillo J, Puga I, Cunha C, Bastos H, Rodrigues F, Lacerda JF, Morais A, Dieguez-Gonzalez R, Heeger PS, Salvatori G, Carvalho A, Garcia-Sastre A, Blander JM, Mantovani A, Garlanda C, Cerutti A.

J Exp Med. 2016 Sep 19;213(10):2167-85. doi: 10.1084/jem.20150282. Epub 2016 Sep 12. Erratum in: J Exp Med. 2017 May 1;214(5):1559.

38.

Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.

Cavalli G, Koenders M, Kalabokis V, Kim J, Tan AC, Garlanda C, Mantovani A, Dagna L, Joosten LA, Dinarello CA.

Rheumatology (Oxford). 2016 Dec;55(12):2220-2229. Epub 2016 Aug 26. Erratum in: Rheumatology (Oxford). 2017 Dec 1;56(12 ):2256.

39.

Cytokine decoy and scavenger receptors as key regulators of immunity and inflammation.

Bonecchi R, Garlanda C, Mantovani A, Riva F.

Cytokine. 2016 Nov;87:37-45. doi: 10.1016/j.cyto.2016.06.023. Epub 2016 Aug 4.

40.

Humoral innate immunity at the crossroad between microbe and matrix recognition: The role of PTX3 in tissue damage.

Doni A, D'Amico G, Morone D, Mantovani A, Garlanda C.

Semin Cell Dev Biol. 2017 Jan;61:31-40. doi: 10.1016/j.semcdb.2016.07.026. Epub 2016 Jul 29. Review.

41.

Expression and function of IL-1R8 (TIR8/SIGIRR): a regulatory member of the IL-1 receptor family in platelets.

Anselmo A, Riva F, Gentile S, Soldani C, Barbagallo M, Mazzon C, Feruglio F, Polentarutti N, Somma P, Carullo P, Angelini C, Bacci M, Mendolicchio GL, Voza A, Nebuloni M, Mantovani A, Garlanda C.

Cardiovasc Res. 2016 Sep;111(4):373-84. doi: 10.1093/cvr/cvw162. Epub 2016 Jun 13. Erratum in: Cardiovasc Res. 2017 Jan;113(1):112.

PMID:
27297888
42.

The Dual Complexity of PTX3 in Health and Disease: A Balancing Act?

Magrini E, Mantovani A, Garlanda C.

Trends Mol Med. 2016 Jun;22(6):497-510. doi: 10.1016/j.molmed.2016.04.007. Epub 2016 May 11. Review.

43.

Regulatory Role of IL-1R8 in Immunity and Disease.

Molgora M, Barajon I, Mantovani A, Garlanda C.

Front Immunol. 2016 Apr 20;7:149. doi: 10.3389/fimmu.2016.00149. eCollection 2016. Review.

44.

Fluid phase recognition molecules in neutrophil-dependent immune responses.

Jaillon S, Ponzetta A, Magrini E, Barajon I, Barbagallo M, Garlanda C, Mantovani A.

Semin Immunol. 2016 Apr;28(2):109-18. doi: 10.1016/j.smim.2016.03.005. Epub 2016 Mar 25. Review.

45.

Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation.

Bonacina F, Barbieri SS, Cutuli L, Amadio P, Doni A, Sironi M, Tartari S, Mantovani A, Bottazzi B, Garlanda C, Tremoli E, Catapano AL, Norata GD.

Biochim Biophys Acta. 2016 Jun;1862(6):1182-90. doi: 10.1016/j.bbadis.2016.03.007. Epub 2016 Mar 11.

46.

Occurrence and significance of tumor-associated neutrophils in patients with colorectal cancer.

Galdiero MR, Bianchi P, Grizzi F, Di Caro G, Basso G, Ponzetta A, Bonavita E, Barbagallo M, Tartari S, Polentarutti N, Malesci A, Marone G, Roncalli M, Laghi L, Garlanda C, Mantovani A, Jaillon S.

Int J Cancer. 2016 Jul 15;139(2):446-56. doi: 10.1002/ijc.30076. Epub 2016 Mar 24.

47.

Glucose availability enhances lipopolysaccharide production and immunogenicity in the opportunistic pathogen Acinetobacter baumannii.

Rossi E, Longo F, Barbagallo M, Peano C, Consolandi C, Pietrelli A, Jaillon S, Garlanda C, Landini P.

Future Microbiol. 2016;11(3):335-49. doi: 10.2217/fmb.15.153. Epub 2016 Mar 2.

PMID:
26934424
48.

The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling.

Bottazzi B, Inforzato A, Messa M, Barbagallo M, Magrini E, Garlanda C, Mantovani A.

J Hepatol. 2016 Jun;64(6):1416-27. doi: 10.1016/j.jhep.2016.02.029. Epub 2016 Feb 26. Review.

49.

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling.

Cappuzzello C, Doni A, Dander E, Pasqualini F, Nebuloni M, Bottazzi B, Mantovani A, Biondi A, Garlanda C, D'Amico G.

J Invest Dermatol. 2016 Jan;136(1):293-300. doi: 10.1038/JID.2015.346.

50.

PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognition.

Garlanda C, Jaillon S, Doni A, Bottazzi B, Mantovani A.

Curr Opin Immunol. 2016 Feb;38:39-44. doi: 10.1016/j.coi.2015.11.002. Epub 2015 Nov 30. Review.

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