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Items: 1 to 50 of 205

1.

Reducing time to pregnancy and facilitating the birth of healthy children through functional analysis of embryo physiology.

Ferrick L, Lee YSL, Gardner DK.

Biol Reprod. 2019 Jan 16. doi: 10.1093/biolre/ioz005. [Epub ahead of print]

PMID:
30649216
2.

Mitochondrial and glycolytic remodeling during nascent neural differentiation of human pluripotent stem cells.

Lees JG, Gardner DK, Harvey AJ.

Development. 2018 Oct 22;145(20). pii: dev168997. doi: 10.1242/dev.168997.

PMID:
30266828
3.

Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance.

Stringer JM, Forster SC, Qu Z, Prokopuk L, O'Bryan MK, Gardner DK, White SJ, Adelson D, Western PS.

BMC Biol. 2018 Sep 20;16(1):104. doi: 10.1186/s12915-018-0569-5.

4.

Forty years of IVF.

Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR.

Fertil Steril. 2018 Jul 15;110(2):185-324.e5. doi: 10.1016/j.fertnstert.2018.06.005. Review.

PMID:
30053940
5.

Physiological oxygen culture reveals retention of metabolic memory in human induced pluripotent stem cells.

Harvey AJ, O'Brien C, Lambshead J, Sheedy JR, Rathjen J, Laslett AL, Gardner DK.

PLoS One. 2018 Mar 15;13(3):e0193949. doi: 10.1371/journal.pone.0193949. eCollection 2018.

6.

Antioxidants improve IVF outcome and subsequent embryo development in the mouse.

Truong T, Gardner DK.

Hum Reprod. 2017 Dec 1;32(12):2404-2413. doi: 10.1093/humrep/dex330.

PMID:
29136144
7.

Will noninvasive methods surpass invasive for assessing gametes and embryos?

Sanchez T, Seidler EA, Gardner DK, Needleman D, Sakkas D.

Fertil Steril. 2017 Nov;108(5):730-737. doi: 10.1016/j.fertnstert.2017.10.004. Review.

PMID:
29101998
8.

Addition of interleukin-6 to mouse embryo culture increases blastocyst cell number and influences the inner cell mass to trophectoderm ratio.

Kelley RL, Gardner DK.

Clin Exp Reprod Med. 2017 Sep;44(3):119-125. doi: 10.5653/cerm.2017.44.3.119. Epub 2017 Sep 26.

9.

De novo transcriptome assembly for the spiny mouse (Acomys cahirinus).

Mamrot J, Legaie R, Ellery SJ, Wilson T, Seemann T, Powell DR, Gardner DK, Walker DW, Temple-Smith P, Papenfuss AT, Dickinson H.

Sci Rep. 2017 Aug 21;7(1):8996. doi: 10.1038/s41598-017-09334-7.

10.

Pluripotent Stem Cell Metabolism and Mitochondria: Beyond ATP.

Lees JG, Gardner DK, Harvey AJ.

Stem Cells Int. 2017;2017:2874283. doi: 10.1155/2017/2874283. Epub 2017 Jul 19. Review.

11.

Impact of the IVF laboratory environment on human preimplantation embryo phenotype.

Gardner DK, Kelley RL.

J Dev Orig Health Dis. 2017 Aug;8(4):418-435. doi: 10.1017/S2040174417000368. Epub 2017 Jun 14. Review.

PMID:
28610639
12.

In vitro culture of individual mouse preimplantation embryos: the role of embryo density, microwells, oxygen, timing and conditioned media.

Kelley RL, Gardner DK.

Reprod Biomed Online. 2017 May;34(5):441-454. doi: 10.1016/j.rbmo.2017.02.001. Epub 2017 Feb 15.

PMID:
28268069
13.

Src Family Kinases and p38 Mitogen-Activated Protein Kinases Regulate Pluripotent Cell Differentiation in Culture.

Tan BS, Kwek J, Wong CK, Saner NJ, Yap C, Felquer F, Morris MB, Gardner DK, Rathjen PD, Rathjen J.

PLoS One. 2016 Oct 10;11(10):e0163244. doi: 10.1371/journal.pone.0163244. eCollection 2016.

14.

Placental Growth Factor Is Secreted by the Human Endometrium and Has Potential Important Functions during Embryo Development and Implantation.

Binder NK, Evans J, Salamonsen LA, Gardner DK, Kaitu'u-Lino TJ, Hannan NJ.

PLoS One. 2016 Oct 6;11(10):e0163096. doi: 10.1371/journal.pone.0163096. eCollection 2016.

15.

Development of a generally applicable morphokinetic algorithm capable of predicting the implantation potential of embryos transferred on Day 3.

Petersen BM, Boel M, Montag M, Gardner DK.

Hum Reprod. 2016 Oct;31(10):2231-44. doi: 10.1093/humrep/dew188. Epub 2016 Sep 8.

16.
17.

Combined effects of individual culture and atmospheric oxygen on preimplantation mouse embryos in vitro.

Kelley RL, Gardner DK.

Reprod Biomed Online. 2016 Nov;33(5):537-549. doi: 10.1016/j.rbmo.2016.08.003. Epub 2016 Aug 20.

PMID:
27569702
18.

Uterine flushing proteome of the tammar wallaby after reactivation from diapause.

Martin FC, Ang CS, Gardner DK, Renfree MB, Shaw G.

Reproduction. 2016 Nov;152(5):491-505. doi: 10.1530/REP-16-0154. Epub 2016 Aug 2.

PMID:
27486272
19.

Regulation of amino acid transporters in pluripotent cell populations in the embryo and in culture; novel roles for sodium-coupled neutral amino acid transporters.

Tan BSN, Rathjen PD, Harvey AJ, Gardner DK, Rathjen J.

Mech Dev. 2016 Aug;141:32-39. doi: 10.1016/j.mod.2016.06.003. Epub 2016 Jun 30.

20.

Antioxidants improve mouse preimplantation embryo development and viability.

Truong TT, Soh YM, Gardner DK.

Hum Reprod. 2016 Jul;31(7):1445-54. doi: 10.1093/humrep/dew098. Epub 2016 May 10.

PMID:
27165621
21.

Metaboloepigenetic Regulation of Pluripotent Stem Cells.

Harvey AJ, Rathjen J, Gardner DK.

Stem Cells Int. 2016;2016:1816525. doi: 10.1155/2016/1816525. Epub 2015 Dec 29. Review.

22.

The impact of physiological oxygen during culture, and vitrification for cryopreservation, on the outcome of extended culture in human IVF.

Gardner DK.

Reprod Biomed Online. 2016 Feb;32(2):137-41. doi: 10.1016/j.rbmo.2015.11.008. Epub 2015 Nov 25.

23.

Biomarkers in reproductive medicine: the quest for new answers.

Simon C, Sakkas D, Gardner DK, Critchley HO.

Hum Reprod Update. 2015 Nov-Dec;21(6):695-7. doi: 10.1093/humupd/dmv043. Epub 2015 Sep 19. No abstract available.

PMID:
26386470
24.

Confirmed dioestrus in pseudopregnant mice using vaginal exfoliative cytology improves embryo transfer implantation rate.

Mamrot J, Pangestu M, Walker D, Gardner DK, Dickinson H.

Reprod Biomed Online. 2015 Oct;31(4):538-43. doi: 10.1016/j.rbmo.2015.06.020. Epub 2015 Jul 8.

PMID:
26276041
25.

The effects of chemical and physical factors on mammalian embryo culture and their importance for the practice of assisted human reproduction.

Wale PL, Gardner DK.

Hum Reprod Update. 2016 Jan-Feb;22(1):2-22. doi: 10.1093/humupd/dmv034. Epub 2015 Jul 22. Review.

PMID:
26207016
26.

Distinct profiles of human embryonic stem cell metabolism and mitochondria identified by oxygen.

Lees JG, Rathjen J, Sheedy JR, Gardner DK, Harvey AJ.

Reproduction. 2015 Oct;150(4):367-82. doi: 10.1530/REP-14-0633. Epub 2015 Jul 9.

PMID:
26159831
27.

Combined parental obesity negatively impacts preimplantation mouse embryo development, kinetics, morphology and metabolism.

Finger BJ, Harvey AJ, Green MP, Gardner DK.

Hum Reprod. 2015 Sep;30(9):2084-96. doi: 10.1093/humrep/dev142. Epub 2015 Jun 18.

PMID:
26089300
28.

Fathers that are born small program alterations in the next-generation preimplantation rat embryos.

Master JS, Thouas GA, Harvey AJ, Sheedy JR, Hannan NJ, Gardner DK, Wlodek ME.

J Nutr. 2015 May;145(5):876-83. doi: 10.3945/jn.114.205724. Epub 2015 Mar 25.

PMID:
25809684
29.

Blastocyst metabolism.

Gardner DK, Harvey AJ.

Reprod Fertil Dev. 2015 May;27(4):638-54. doi: 10.1071/RD14421. Review.

PMID:
25751298
30.

Male obesity is associated with changed spermatozoa Cox4i1 mRNA level and altered seminal vesicle fluid composition in a mouse model.

Binder NK, Sheedy JR, Hannan NJ, Gardner DK.

Mol Hum Reprod. 2015 May;21(5):424-34. doi: 10.1093/molehr/gav010. Epub 2015 Mar 2.

PMID:
25731709
31.

Paternal obesity in a rodent model affects placental gene expression in a sex-specific manner.

Binder NK, Beard SA, Kaitu'u-Lino TJ, Tong S, Hannan NJ, Gardner DK.

Reproduction. 2015 May;149(5):435-44. doi: 10.1530/REP-14-0676. Epub 2015 Feb 27.

PMID:
25725082
32.

Redox and anti-oxidant state within cattle oocytes following in vitro maturation with bone morphogenetic protein 15 and follicle stimulating hormone.

Sutton-McDowall ML, Purdey M, Brown HM, Abell AD, Mottershead DG, Cetica PD, Dalvit GC, Goldys EM, Gilchrist RB, Gardner DK, Thompson JG.

Mol Reprod Dev. 2015 Apr;82(4):281-94. doi: 10.1002/mrd.22470. Epub 2015 Feb 26.

PMID:
25721374
33.

Low female birth weight and advanced maternal age programme alterations in next-generation blastocyst development.

Master JS, Thouas GA, Harvey AJ, Sheedy JR, Hannan NJ, Gardner DK, Wlodek ME.

Reproduction. 2015 May;149(5):497-510. doi: 10.1530/REP-14-0619. Epub 2015 Feb 9.

PMID:
25667431
34.

Spatial asynchronous transfer of cleavage-stage mouse embryos to the uterus compromises fetal development.

Walker KJ, Green MP, Gardner DK.

Mol Reprod Dev. 2015 Feb;82(2):80. doi: 10.1002/mrd.22456. Epub 2015 Feb 4. No abstract available.

PMID:
25652094
35.

Lactate production by the mammalian blastocyst: manipulating the microenvironment for uterine implantation and invasion?

Gardner DK.

Bioessays. 2015 Apr;37(4):364-71. doi: 10.1002/bies.201400155. Epub 2015 Jan 23.

36.

Diagnosis of human preimplantation embryo viability.

Gardner DK, Meseguer M, Rubio C, Treff NR.

Hum Reprod Update. 2015 Nov-Dec;21(6):727-47. doi: 10.1093/humupd/dmu064. Epub 2015 Jan 6. Review.

PMID:
25567750
37.

Developmental kinetics of cleavage stage mouse embryos are related to their subsequent carbohydrate and amino acid utilization at the blastocyst stage.

Lee YS, Thouas GA, Gardner DK.

Hum Reprod. 2015 Mar;30(3):543-52. doi: 10.1093/humrep/deu334. Epub 2015 Jan 6.

PMID:
25567621
38.

Soluble ligands and their receptors in human embryo development and implantation.

Thouas GA, Dominguez F, Green MP, Vilella F, Simon C, Gardner DK.

Endocr Rev. 2015 Feb;36(1):92-130. doi: 10.1210/er.2014-1046. Epub 2014 Dec 30. Review.

PMID:
25548832
39.

Oxygen modulates human embryonic stem cell metabolism in the absence of changes in self-renewal.

Harvey AJ, Rathjen J, Yu LJ, Gardner DK.

Reprod Fertil Dev. 2016 Mar;28(4):446-58. doi: 10.1071/RD14013.

PMID:
25145274
40.

Endometrial signals improve embryo outcome: functional role of vascular endothelial growth factor isoforms on embryo development and implantation in mice.

Binder NK, Evans J, Gardner DK, Salamonsen LA, Hannan NJ.

Hum Reprod. 2014 Oct 10;29(10):2278-86. doi: 10.1093/humrep/deu211. Epub 2014 Aug 14.

PMID:
25124669
41.

Laboratory procedures for human in vitro fertilization.

Balaban B, Sakkas D, Gardner DK.

Semin Reprod Med. 2014 Jul;32(4):272-82. doi: 10.1055/s-0034-1375179. Epub 2014 Jun 11. Review.

PMID:
24919026
42.

Embryo transfer cannot delineate between the maternal pregnancy environment and germ line effects in the transgenerational transmission of disease in rats.

Tran M, Gallo LA, Hanvey AN, Jefferies AJ, Westcott KT, Cullen-McEwen LA, Gardner DK, Moritz KM, Wlodek ME.

Am J Physiol Regul Integr Comp Physiol. 2014 Apr 15;306(8):R607-18. doi: 10.1152/ajpregu.00523.2013. Epub 2014 Feb 12.

43.

Cryopreservation in ART and concerns with contamination during cryobanking.

Larman MG, Hashimoto S, Morimoto Y, Gardner DK.

Reprod Med Biol. 2014 Feb 5;13(3):107-117. doi: 10.1007/s12522-014-0176-2. eCollection 2014 Jul. Review.

44.

Neonatal outcomes following in utero exposure to buprenorphine/naloxone or methadone.

Gawronski KM, Prasad MR, Backes CR, Lehman KJ, Gardner DK, Cordero L.

SAGE Open Med. 2014 Apr 15;2:2050312114530282. doi: 10.1177/2050312114530282. eCollection 2014.

45.

Mammalian preimplantation embryo culture.

Gardner DK, Lane M.

Methods Mol Biol. 2014;1092:167-82. doi: 10.1007/978-1-60327-292-6_11.

PMID:
24318820
46.

Ultrarapid vitrification of mouse oocytes and embryos.

Larman MG, Gardner DK.

Methods Mol Biol. 2014;1092:153-65. doi: 10.1007/978-1-60327-292-6_10.

PMID:
24318819
47.

Impact of oxygen concentration on adult murine pre-antral follicle development in vitro and the corresponding metabolic profile.

Gook DA, Edgar DH, Lewis K, Sheedy JR, Gardner DK.

Mol Hum Reprod. 2014 Jan;20(1):31-41. doi: 10.1093/molehr/gat062. Epub 2013 Sep 6.

PMID:
24013158
48.

Oxygen affects the ability of mouse blastocysts to regulate ammonium.

Wale PL, Gardner DK.

Biol Reprod. 2013 Sep 27;89(3):75. doi: 10.1095/biolreprod.113.109256. Print 2013 Sep.

PMID:
23803557
49.

Culture environment regulates amino acid turnover and glucose utilisation in human ES cells.

Rathjen J, Yeo C, Yap C, Tan BS, Rathjen PD, Gardner DK.

Reprod Fertil Dev. 2014 Jun;26(5):703-16. doi: 10.1071/RD12276.

PMID:
23759283
50.

Human and mouse embryonic development, metabolism and gene expression are altered by an ammonium gradient in vitro.

Gardner DK, Hamilton R, McCallie B, Schoolcraft WB, Katz-Jaffe MG.

Reproduction. 2013 Jun 14;146(1):49-61. doi: 10.1530/REP-12-0348. Print 2013 Jul.

PMID:
23613618

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