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Items: 1 to 50 of 244

1.

Peroxisome proliferator-activated receptor γ agonism attenuates endotoxaemia-induced muscle protein loss and lactate accumulation in rats.

Crossland H, Constantin-Teodosiu D, Gardiner SM, Greenhaff PL.

Clin Sci (Lond). 2017 Jun 22;131(13):1437-1447. doi: 10.1042/CS20170958. Print 2017 Jul 1.

PMID:
28536293
2.

Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease.

Baker JG, Gardiner SM, Woolard J, Fromont C, Jadhav GP, Mistry SN, Thompson KSJ, Kellam B, Hill SJ, Fischer PM.

FASEB J. 2017 Jul;31(7):3150-3166. doi: 10.1096/fj.201601305R. Epub 2017 Apr 11.

3.

Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring.

Gray C, Gardiner SM, Elmes M, Gardner DS.

Br J Nutr. 2016 Feb 28;115(4):594-604. doi: 10.1017/S0007114515004936. Epub 2015 Dec 10.

PMID:
26653028
4.

Excess maternal salt intake produces sex-specific hypertension in offspring: putative roles for kidney and gastrointestinal sodium handling.

Gray C, Al-Dujaili EA, Sparrow AJ, Gardiner SM, Craigon J, Welham SJ, Gardner DS.

PLoS One. 2013 Aug 22;8(8):e72682. doi: 10.1371/journal.pone.0072682. eCollection 2013.

5.

Maternal fructose and/or salt intake and reproductive outcome in the rat: effects on growth, fertility, sex ratio, and birth order.

Gray C, Long S, Green C, Gardiner SM, Craigon J, Gardner DS.

Biol Reprod. 2013 Sep;89(3):51.

PMID:
23759309
6.

Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists.

Mistry SN, Baker JG, Fischer PM, Hill SJ, Gardiner SM, Kellam B.

J Med Chem. 2013 May 23;56(10):3852-65. doi: 10.1021/jm400348g. Epub 2013 May 10.

7.

Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses.

Baker JG, Kemp P, March J, Fretwell L, Hill SJ, Gardiner SM.

FASEB J. 2011 Dec;25(12):4486-97. doi: 10.1096/fj.11-192435. Epub 2011 Aug 24.

8.

Time to take action on climate communication.

Bowman TE, Maibach E, Mann ME, Somerville RC, Seltser BJ, Fischhoff B, Gardiner SM, Gould RJ, Leiserowitz A, Yohe G.

Science. 2010 Nov 19;330(6007):1044. doi: 10.1126/science.330.6007.1044. No abstract available.

PMID:
21097916
9.

Possible involvement of GLP-1(9-36) in the regional haemodynamic effects of GLP-1(7-36) in conscious rats.

Gardiner SM, March JE, Kemp PA, Bennett T, Baker DJ.

Br J Pharmacol. 2010 Sep;161(1):92-102. doi: 10.1111/j.1476-5381.2010.00867.x.

10.

Low-dose dexamethasone prevents endotoxaemia-induced muscle protein loss and impairment of carbohydrate oxidation in rat skeletal muscle.

Crossland H, Constantin-Teodosiu D, Greenhaff PL, Gardiner SM.

J Physiol. 2010 Apr 15;588(Pt 8):1333-47. doi: 10.1113/jphysiol.2009.183699. Epub 2010 Feb 22.

11.

Effects of endotoxaemia on protein metabolism in rat fast-twitch skeletal muscle and myocardium.

Murton AJ, Alamdari N, Gardiner SM, Constantin-Teodosiu D, Layfield R, Bennett T, Greenhaff PL.

PLoS One. 2009 Sep 14;4(9):e6945. doi: 10.1371/journal.pone.0006945.

12.

Factors influencing the regional haemodynamic responses to methanandamide and anandamide in conscious rats.

Gardiner SM, March JE, Kemp PA, Bennett T.

Br J Pharmacol. 2009 Oct;158(4):1143-52. doi: 10.1111/j.1476-5381.2009.00363.x. Epub 2009 Aug 20.

13.

Mechanisms involved in the regional haemodynamic effects of intermedin (adrenomedullin 2) compared with adrenomedullin in conscious rats.

Jolly L, March JE, Kemp PA, Bennett T, Gardiner SM.

Br J Pharmacol. 2009 Aug;157(8):1502-13. doi: 10.1111/j.1476-5381.2009.00306.x.

14.

Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats.

Ho WS, Gardiner SM.

Br J Pharmacol. 2009 Jan;156(1):94-104. doi: 10.1111/j.1476-5381.2008.00034.x.

15.

A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle.

Crossland H, Constantin-Teodosiu D, Gardiner SM, Constantin D, Greenhaff PL.

J Physiol. 2008 Nov 15;586(22):5589-600. doi: 10.1113/jphysiol.2008.160150. Epub 2008 Sep 25.

16.

Regional haemodynamic responses to adenosine receptor activation vary across time following lipopolysaccharide treatment in conscious rats.

Jolly L, March JE, Kemp PA, Bennett T, Gardiner SM.

Br J Pharmacol. 2008 Aug;154(8):1600-10. doi: 10.1038/bjp.2008.205. Epub 2008 May 26.

17.

Autonomic nervous system-dependent and -independent cardiovascular effects of exendin-4 infusion in conscious rats.

Gardiner SM, March JE, Kemp PA, Bennett T.

Br J Pharmacol. 2008 May;154(1):60-71. doi: 10.1038/bjp.2008.75. Epub 2008 Mar 3.

18.

Temporal changes in the involvement of pyruvate dehydrogenase complex in muscle lactate accumulation during lipopolysaccharide infusion in rats.

Alamdari N, Constantin-Teodosiu D, Murton AJ, Gardiner SM, Bennett T, Layfield R, Greenhaff PL.

J Physiol. 2008 Mar 15;586(6):1767-75. doi: 10.1113/jphysiol.2007.149625. Epub 2008 Jan 24.

19.

Vascular pharmacology of a novel cannabinoid-like compound, 3-(5-dimethylcarbamoyl-pent-1-enyl)-N-(2-hydroxy-1-methyl-ethyl)benzamide (VSN16) in the rat.

Hoi PM, Visintin C, Okuyama M, Gardiner SM, Kaup SS, Bennett T, Baker D, Selwood DL, Hiley CR.

Br J Pharmacol. 2007 Nov;152(5):751-64. Epub 2007 Sep 24.

20.

Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats.

Wheal AJ, Bennett T, Randall MD, Gardiner SM.

Br J Pharmacol. 2007 Nov;152(5):717-24. Epub 2007 Aug 13.

21.

Reply to 'Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities'.

Gardiner SM, Keyte J, Bennett T.

Nat Med. 2007 Jun;13(6):661; author reply 661-2. No abstract available.

PMID:
17554326
22.

The in vitro and in vivo cardiovascular effects of Delta9-tetrahydrocannabinol in rats made hypertensive by chronic inhibition of nitric-oxide synthase.

O'Sullivan SE, Randall MD, Gardiner SM.

J Pharmacol Exp Ther. 2007 May;321(2):663-72. Epub 2007 Feb 6.

PMID:
17284670
23.

Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro.

Wheal AJ, Bennett T, Randall MD, Gardiner SM.

Br J Pharmacol. 2007 Mar;150(5):662-71. Epub 2007 Jan 22.

24.

A comparison between the cardiovascular actions of urocortin 1 and urocortin 2 (stresscopin-related peptide) in conscious rats.

Gardiner SM, March JE, Kemp PA, Bennett T.

J Pharmacol Exp Ther. 2007 Apr;321(1):221-6. Epub 2007 Jan 19.

PMID:
17237259
25.
26.

Regional hemodynamic effects of neutral endopeptidase inhibition and angiotensin (AT(1)) receptor antagonism alone or in combination in conscious spontaneously hypertensive rats.

Gardiner SM, March JE, Kemp PA, Ballard SA, Bennett T.

J Pharmacol Exp Ther. 2006 Oct;319(1):340-8. Epub 2006 Jul 6.

PMID:
16825530
27.

Regional heterogeneity in the haemodynamic responses to urotensin II infusion in relation to UT receptor localisation.

Gardiner SM, March JE, Kemp PA, Maguire JJ, Kuc RE, Davenport AP, Bennett T.

Br J Pharmacol. 2006 Mar;147(6):612-21.

28.

Mesenteric vasoconstriction and hindquarters vasodilatation accompany the pressor actions of exendin-4 in conscious rats.

Gardiner SM, March JE, Kemp PA, Bennett T.

J Pharmacol Exp Ther. 2006 Feb;316(2):852-9. Epub 2005 Oct 12.

PMID:
16221740
29.

Involvement of CB1-receptors and beta-adrenoceptors in the regional hemodynamic responses to lipopolysaccharide infusion in conscious rats.

Gardiner SM, March JE, Kemp PA, Bennett T.

Am J Physiol Heart Circ Physiol. 2005 May;288(5):H2280-8. Epub 2004 Dec 16.

30.

Cannabinoids and endotoxemia.

Gardiner SM, Bennett T.

Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H451; author reply H451-2. No abstract available.

31.

Hemodynamic effects of phosphodiesterase 5 and angiotensin-converting enzyme inhibition alone or in combination in conscious SHR.

Gardiner SM, March JE, Kemp PA, Ballard SA, Hawkeswood E, Hughes B, Bennett T.

J Pharmacol Exp Ther. 2005 Jan;312(1):265-71. Epub 2004 Sep 27.

PMID:
15452190
32.

Bolus injection of human UII in conscious rats evokes a biphasic haemodynamic response.

Gardiner SM, March JE, Kemp PA, Bennett T.

Br J Pharmacol. 2004 Oct;143(3):422-30. Epub 2004 Aug 31.

33.

Regional hemodynamic actions of selective corticotropin-releasing factor type 2 receptor ligands in conscious rats.

Gardiner SM, March JE, Kemp PA, Davenport AP, Wiley KE, Bennett T.

J Pharmacol Exp Ther. 2005 Jan;312(1):53-60. Epub 2004 Aug 24.

PMID:
15328375
34.

The effect of the beta2-adrenoceptor agonist prodrug BRL-47672 on cardiovascular function, skeletal muscle myosin heavy chain, and MyoD expression in the rat.

Jones SW, Baker DJ, Gardiner SM, Bennett T, Timmons JA, Greenhaff PL.

J Pharmacol Exp Ther. 2004 Dec;311(3):1225-31. Epub 2004 Jul 8.

PMID:
15243031
35.
37.

Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats.

Gardiner SM, March JE, Kemp PA, Fallgren B, Bennett T.

Br J Pharmacol. 2004 Feb;141(4):634-43. Epub 2004 Jan 26.

38.

Haemodynamic effects of the selective phosphodiesterase 5 inhibitor, UK-357,903, in conscious SHR.

Gardiner SM, March JE, Kemp PA, Ballard SA, Hawkeswood E, Hughes B, Bennett T.

Br J Pharmacol. 2004 Jan;141(1):114-22. Epub 2003 Dec 8.

39.

Evaluation of two carrier protein-angiotensin I conjugate vaccines to assess their future potential to control high blood pressure (hypertension) in man.

Downham MR, Auton TR, Rosul A, Sharp HL, Sjöström L, Rushton A, Richards JP, Mant TG, Gardiner SM, Bennett T, Glover JF.

Br J Clin Pharmacol. 2003 Nov;56(5):505-12.

40.

Acute cardiovascular effects of sibutramine in conscious rats.

Woolard J, Bennett T, Dunn WR, Heal DJ, Aspley S, Gardiner SM.

J Pharmacol Exp Ther. 2004 Mar;308(3):1102-10. Epub 2003 Nov 21.

PMID:
14634034
41.
42.

Comparative regional haemodynamic effects of the nitric oxide synthase inhibitors, S-methyl-L-thiocitrulline and L-NAME, in conscious rats.

Wakefield ID, March JE, Kemp PA, Valentin JP, Bennett T, Gardiner SM.

Br J Pharmacol. 2003 Jul;139(6):1235-43.

43.

Effects of in vivo lipopolysaccharide infusion on vasoconstrictor function of rat isolated mesentery, kidney, and aorta.

Farmer MR, Roberts RE, Gardiner SM, Ralevic V.

J Pharmacol Exp Ther. 2003 Aug;306(2):538-45. Epub 2003 May 2.

PMID:
12730359
44.

Characterization of the endokinins: human tachykinins with cardiovascular activity.

Page NM, Bell NJ, Gardiner SM, Manyonda IT, Brayley KJ, Strange PG, Lowry PJ.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):6245-50. Epub 2003 Apr 25.

45.

Fostering orphan receptors: an indispensable role for integrative, in vivo, haemodynamic studies.

Bennett T, Gardiner SM.

Curr Opin Pharmacol. 2003 Apr;3(2):140-5. Review.

PMID:
12681235
46.

The real tragedy of the commons.

Gardiner SM.

Philos Public Aff. 2001 Fall;30(4):387-416. No abstract available.

PMID:
12653120
47.

Vasoconstrictor responsiveness of tail arteries from endotoxaemic rats.

Ralevic V, Farmer MR, Gardiner SM.

Eur J Pharmacol. 2003 Jan 24;460(2-3):145-53.

PMID:
12559375
48.
49.

Complex regional haemodynamic effects of anandamide in conscious rats.

Gardiner SM, March JE, Kemp PA, Bennett T.

Br J Pharmacol. 2002 Apr;135(8):1889-96.

50.

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