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Intensive care for organ preservation: A four-stage pathway.

Gardiner D, Shaw DM, Kilcullen JK, Dalle Ave AL.

J Intensive Care Soc. 2019 Nov;20(4):335-340. doi: 10.1177/1751143719840254. Epub 2019 Apr 25.


Assessing the utility of an IoS application in the perioperative care of spine surgery patients: the NeuroPath Pilot study.

Glauser G, Ali ZS, Gardiner D, Ramayya AG, Pessoa R, Grady MS, Welch WC, Zager EL, Sim E, Haughey V, Wells B, Restuccia M, Tait G, Fala G, Malhotra NR.

Mhealth. 2019 Sep 24;5:40. doi: 10.21037/mhealth.2019.09.01. eCollection 2019.


Gene drives in plants: opportunities and challenges for weed control and engineered resilience.

Barrett LG, Legros M, Kumaran N, Glassop D, Raghu S, Gardiner DM.

Proc Biol Sci. 2019 Sep 25;286(1911):20191515. doi: 10.1098/rspb.2019.1515. Epub 2019 Sep 25.


Donation after circulatory death today: an updated overview of the European landscape.

Lomero M, Gardiner D, Coll E, Haase-Kromwijk B, Procaccio F, Immer F, Gabbasova L, Antoine C, Jushinskis J, Lynch N, Foss S, Bolotinha C, Ashkenazi T, Colenbie L, Zuckermann A, Adamec M, Czerwiński J, Karčiauskaitė S, Ström H, López-Fraga M, Dominguez-Gil B; European Committee on Organ Transplantation of the Council of Europe (CD-P-TO).

Transpl Int. 2019 Sep 3. doi: 10.1111/tri.13506. [Epub ahead of print]


How the mode of organ donation affects family behaviour at the time of organ donation.

Prescott J, Gardiner D, Hogg L, Harvey D.

J Intensive Care Soc. 2019 Aug;20(3):204-207. doi: 10.1177/1751143718807842. Epub 2018 Oct 17.


Deletion of the Glutaredoxin-2 Gene Protects Mice from Diet-Induced Weight Gain, Which Correlates with Increased Mitochondrial Respiration and Proton Leaks in Skeletal Muscle.

Young A, Gardiner D, Kuksal N, Gill R, O'Brien M, Mailloux RJ.

Antioxid Redox Signal. 2019 Dec;31(17):1272-1288. doi: 10.1089/ars.2018.7715. Epub 2019 Aug 14.


Heterologous expression of intact biosynthetic gene clusters in Fusarium graminearum.

Nielsen MR, Wollenberg RD, Westphal KR, Sondergaard TE, Wimmer R, Gardiner DM, Sørensen JL.

Fungal Genet Biol. 2019 Jul 4;132:103248. doi: 10.1016/j.fgb.2019.103248. [Epub ahead of print]


Neuroscience and legal challenges to brainstem criteria of death in the UK. A reply.

McGee A, Gardiner D.

Anaesthesia. 2019 Jul;74(7):944. doi: 10.1111/anae.14729. No abstract available.


Are food exposures obtained through commercial market panels representative of the general population? Implications for outbreak investigations.

Inns T, Curtis D, Crook P, Vivancos R, Gardiner D, McCarthy N, Mook P.

Epidemiol Infect. 2019 Jan;147:e99. doi: 10.1017/S0950268819000219.


Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018.

Eyre DW, Town K, Street T, Barker L, Sanderson N, Cole MJ, Mohammed H, Pitt R, Gobin M, Irish C, Gardiner D, Sedgwick J, Beck C, Saunders J, Turbitt D, Cook C, Phin N, Nathan B, Horner P, Fifer H.

Euro Surveill. 2019 Mar;24(10). doi: 10.2807/1560-7917.ES.2019.24.10.1900147.


A Randomized, Double-Blind, Placebo-Controlled, First-Time-in-Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of GSK3389404 in Healthy Subjects.

Han K, Cremer J, Elston R, Oliver S, Baptiste-Brown S, Chen S, Gardiner D, Davies M, Saunders J, Hamatake R, Losos J, Leivers M, Hood S, van der Berg F, Paff M, Ritter JM, Theodore D.

Clin Pharmacol Drug Dev. 2019 Aug;8(6):790-801. doi: 10.1002/cpdd.670. Epub 2019 Mar 12.


Regulation of a novel Fusarium cytokinin in Fusarium pseudograminearum.

Blum A, Benfield AH, Sørensen JL, Nielsen MR, Bachleitner S, Studt L, Beccari G, Covarelli L, Batley J, Gardiner DM.

Fungal Biol. 2019 Mar;123(3):255-266. doi: 10.1016/j.funbio.2018.12.009. Epub 2019 Jan 7.


Oxygen saturation and haemodynamic changes prior to circulatory arrest: Implications for transplantation and resuscitation.

Gilhooley C, Burnhill G, Gardiner D, Vyas H, Davies P.

J Intensive Care Soc. 2019 Feb;20(1):27-33. doi: 10.1177/1751143718764541. Epub 2018 May 10.


Enhanced recovery after elective spinal and peripheral nerve surgery: pilot study from a single institution.

Ali ZS, Flanders TM, Ozturk AK, Malhotra NR, Leszinsky L, McShane BJ, Gardiner D, Rupich K, Chen HI, Schuster J, Marcotte PJ, Kallan MJ, Grady MS, Fleisher LA, Welch WC.

J Neurosurg Spine. 2019 Jan 25:1-9. doi: 10.3171/2018.9.SPINE18681. [Epub ahead of print]


Differences in the definition of brain death and their legal impact on intensive care practice.

McGee A, Gardiner D.

Anaesthesia. 2019 May;74(5):569-572. doi: 10.1111/anae.14568. Epub 2019 Jan 23. No abstract available.


There it is! Fusarium pseudograminearum did not lose the fusaristatin gene cluster after all.

Wollenberg RD, Sondergaard TE, Nielsen MR, Knutsson S, Pedersen TB, Westphal KR, Wimmer R, Gardiner DM, Sørensen JL.

Fungal Biol. 2019 Jan;123(1):10-17. doi: 10.1016/j.funbio.2018.10.004. Epub 2018 Oct 28.


Nanoscale enrichment of the cytosolic enzyme trichodiene synthase near reorganized endoplasmic reticulum in Fusarium graminearum.

Boenisch MJ, Blum A, Broz KL, Gardiner DM, Kistler HC.

Fungal Genet Biol. 2019 Mar;124:73-77. doi: 10.1016/j.fgb.2018.12.008. Epub 2018 Dec 21.


Pharmacokinetics, Safety, and Tolerability Evaluation of Single and Multiple Doses of GSK3342830 in Healthy Volunteers.

Tenero D, Farinola N, Berkowitz EM, Tiffany CA, Qian Y, Xue Z, Raychaudhuri A, Gardiner DF.

Clin Pharmacol Drug Dev. 2019 Aug;8(6):754-764. doi: 10.1002/cpdd.637. Epub 2018 Dec 10.


Genome Sequences of Three Isolates of Fusarium verticillioides.

Gardiner DM.

Microbiol Resour Announc. 2018 Aug 30;7(8). pii: e00918-18. doi: 10.1128/MRA.00918-18. eCollection 2018 Aug.


Conscientious objection to organ donation: Authors' reply.

Shaw D, Gardiner D, Lewis P, Jansen N, Wind T, Samuel U, Georgieva D, Ploeg R, Broderick A.

J Intensive Care Soc. 2018 Nov;19(4):NP5-NP6. doi: 10.1177/1751143718777168. Epub 2018 May 28. No abstract available.


Identification of Antimalarial Inhibitors Using Late-Stage Gametocytes in a Phenotypic Live/Dead Assay.

Spicer TP, Gardiner DL, Schoenen FJ, Roy S, Griffin PR, Chase P, Scampavia L, Hodder P, Trenholme KR.

SLAS Discov. 2019 Jan;24(1):38-46. doi: 10.1177/2472555218796410. Epub 2018 Aug 24.


Use of an ingredient-based analysis to investigate a national outbreak of Escherichia coli O157, United Kingdom, July 2016.

Gardiner D, Gobin M, Verlander NQ, Oliver I, Hawker J.

Euro Surveill. 2018 Jun;23(26). doi: 10.2807/1560-7917.ES.2018.23.26.1700627.


Operational burden of implementing Salmonella Enteritidis and Typhimurium cluster detection using whole genome sequencing surveillance data in England: a retrospective assessment.

Mook P, Gardiner D, Verlander NQ, McCormick J, Usdin M, Crook P, Jenkins C, Dallman TJ.

Epidemiol Infect. 2018 Aug;146(11):1452-1460. doi: 10.1017/S0950268818001589. Epub 2018 Jul 2.


Regeneration: sooner rather than later.

Bryant SV, Gardiner DM.

Int J Dev Biol. 2018;62(6-7-8):363-368. doi: 10.1387/ijdb.170269dg.


Use of gender distribution in routine surveillance data to detect potential transmission of gastrointestinal infections among men who have sex with men in England.

Mook P, Gardiner D, Kanagarajah S, Kerac M, Hughes G, Field N, McCarthy N, Rawlings C, Simms I, Lane C, Crook PD.

Epidemiol Infect. 2018 Aug;146(11):1468-1477. doi: 10.1017/S0950268818001681. Epub 2018 Jun 20.


An open-label, multiple ascending dose study of the anti-CTLA-4 antibody ipilimumab in viremic HIV patients.

Colston E, Grasela D, Gardiner D, Bucy RP, Vakkalagadda B, Korman AJ, Lowy I.

PLoS One. 2018 Jun 7;13(6):e0198158. doi: 10.1371/journal.pone.0198158. eCollection 2018.


The Rule of Threes: three factors that triple the likelihood of families overriding first person consent for organ donation in the UK.

Morgan J, Hopkinson C, Hudson C, Murphy P, Gardiner D, McGowan O, Miller C.

J Intensive Care Soc. 2018 May;19(2):101-106. doi: 10.1177/1751143717738194. Epub 2017 Nov 15.


Initial Assessment of the Risk Assessment and Prediction Tool in a Heterogeneous Neurosurgical Patient Population.

Piazza M, Sharma N, Osiemo B, McClintock S, Missimer E, Gardiner D, Maloney E, Callahan D, Smith JL, Welch W, Schuster J, Grady MS, Malhotra NR.

Neurosurgery. 2019 Jul 1;85(1):50-57. doi: 10.1093/neuros/nyy197.


National outbreak of Shiga toxin-producing Escherichia coli O157:H7 linked to mixed salad leaves, United Kingdom, 2016.

Gobin M, Hawker J, Cleary P, Inns T, Gardiner D, Mikhail A, McCormick J, Elson R, Ready D, Dallman T, Roddick I, Hall I, Willis C, Crook P, Godbole G, Tubin-Delic D, Oliver I.

Euro Surveill. 2018 May;23(18). doi: 10.2807/1560-7917.ES.2018.23.18.17-00197.


Circulatory Arrest, Brain Arrest and Death Determination.

Shemie SD, Gardiner D.

Front Cardiovasc Med. 2018 Mar 13;5:15. doi: 10.3389/fcvm.2018.00015. eCollection 2018.


Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0.

Sperschneider J, Dodds PN, Gardiner DM, Singh KB, Taylor JM.

Mol Plant Pathol. 2018 Sep;19(9):2094-2110. doi: 10.1111/mpp.12682. Epub 2018 May 11.


An International Legal Review of the Relationship between Brain Death and Organ Transplantation.

Aramesh K, Arima H, Gardiner D, Shah SK.

J Clin Ethics. 2018 Spring;29(1):31-42.


Temperature Measurement by a Nanoscale Electron Probe Using Energy Gain and Loss Spectroscopy.

Idrobo JC, Lupini AR, Feng T, Unocic RR, Walden FS, Gardiner DS, Lovejoy TC, Dellby N, Pantelides ST, Krivanek OL.

Phys Rev Lett. 2018 Mar 2;120(9):095901. doi: 10.1103/PhysRevLett.120.095901.


Donation After the Circulatory Determination of Death: Some Responses to Recent Criticisms.

McGee A, Gardiner D.

J Med Philos. 2018 Mar 13;43(2):211-240. doi: 10.1093/jmp/jhx037.


Partial loss of complex I due to NDUFS4 deficiency augments myocardial reperfusion damage by increasing mitochondrial superoxide/hydrogen peroxide production.

Kuksal N, Gardiner D, Qi D, Mailloux RJ.

Biochem Biophys Res Commun. 2018 Mar 25;498(1):214-220. doi: 10.1016/j.bbrc.2018.02.208. Epub 2018 Mar 1.


Selection is required for efficient Cas9-mediated genome editing in Fusarium graminearum.

Gardiner DM, Kazan K.

Fungal Biol. 2018 Feb - Mar;122(2-3):131-137. doi: 10.1016/j.funbio.2017.11.006. Epub 2017 Dec 6.


Conscientious objection to deceased organ donation by healthcare professionals.

Shaw D, Gardiner D, Lewis P, Jansen N, Wind T, Samuel U, Georgieva D, Ploeg R, Broderick A.

J Intensive Care Soc. 2018 Feb;19(1):43-47. doi: 10.1177/1751143717731230. Epub 2017 Sep 14.


Protein S-glutathionylation lowers superoxide/hydrogen peroxide release from skeletal muscle mitochondria through modification of complex I and inhibition of pyruvate uptake.

Gill RM, O'Brien M, Young A, Gardiner D, Mailloux RJ.

PLoS One. 2018 Feb 14;13(2):e0192801. doi: 10.1371/journal.pone.0192801. eCollection 2018.


Right ventricular contractile reserve in tetralogy of Fallot patients with pulmonary regurgitation.

Kingsley C, Ahmad S, Pappachan J, Khambekar S, Smith T, Gardiner D, Shambrook J, Baskar S, Moore R, Veldtman G.

Congenit Heart Dis. 2018 Mar;13(2):288-294. doi: 10.1111/chd.12569. Epub 2018 Jan 5.


Characterization of the impact of glutaredoxin-2 (GRX2) deficiency on superoxide/hydrogen peroxide release from cardiac and liver mitochondria.

Chalker J, Gardiner D, Kuksal N, Mailloux RJ.

Redox Biol. 2018 May;15:216-227. doi: 10.1016/j.redox.2017.12.006. Epub 2017 Dec 14.


Regulation of regeneration by Heparan Sulfate Proteoglycans in the Extracellular Matrix.

Gardiner DM.

Regen Eng Transl Med. 2017 Sep;3(3):192-198. doi: 10.1007/s40883-017-0037-8. Epub 2017 Aug 14.


The Axolotl Limb Regeneration Model as a Discovery Tool for Engineering the Stem Cell Niche.

Seyedhassantehrani N, Otsuka T, Singh S, Gardiner DM.

Curr Stem Cell Rep. 2017 Sep;3(3):156-163. doi: 10.1007/s40778-017-0085-5. Epub 2017 Jul 27.


Transcriptome analysis of Brachypodium during fungal pathogen infection reveals both shared and distinct defense responses with wheat.

Powell JJ, Carere J, Sablok G, Fitzgerald TL, Stiller J, Colgrave ML, Gardiner DM, Manners JM, Vogel JP, Henry RJ, Kazan K.

Sci Rep. 2017 Dec 8;7(1):17212. doi: 10.1038/s41598-017-17454-3.


European Vignettes in Donation After Circulatory Death.

Gardiner D, Wind T, Cole B, van Mook W, Del Río F, Domínguez-Gil B; ELPAT Deceased Donation Working Group.

Prog Transplant. 2017 Sep;27(3):286-290. doi: 10.1177/1526924817715462. Epub 2017 Jul 4.


A multiple near isogenic line (multi-NIL) RNA-seq approach to identify candidate genes underpinning QTL.

Habib A, Powell JJ, Stiller J, Liu M, Shabala S, Zhou M, Gardiner DM, Liu C.

Theor Appl Genet. 2018 Mar;131(3):613-624. doi: 10.1007/s00122-017-3023-0. Epub 2017 Nov 23.


Fusarium crown rot caused by Fusarium pseudograminearum in cereal crops: recent progress and future prospects.

Kazan K, Gardiner DM.

Mol Plant Pathol. 2018 Jul;19(7):1547-1562. doi: 10.1111/mpp.12639. Epub 2018 Feb 9.


Determination of death in donation after circulatory death: an ethical propriety.

McGee A, Gardiner D, Murphy P.

Curr Opin Organ Transplant. 2018 Feb;23(1):114-119. doi: 10.1097/MOT.0000000000000478. Review.


Increasing organ donation rates by revealing recipient details to families of potential donors.

Shaw D, Gardiner D.

J Med Ethics. 2018 Feb;44(2):101-103. doi: 10.1136/medethics-2017-104262. Epub 2017 Sep 7.


The Papworth donation-after-circulatory-death heart technique and its challenge to the permanence standard.

McGee A, Gardiner D.

J Heart Lung Transplant. 2017 Aug 10. pii: S1053-2498(17)31949-6. doi: 10.1016/j.healun.2017.08.004. [Epub ahead of print] No abstract available.


The cereal pathogen Fusarium pseudograminearum produces a new class of active cytokinins during infection.

Sørensen JL, Benfield AH, Wollenberg RD, Westphal K, Wimmer R, Nielsen MR, Nielsen KF, Carere J, Covarelli L, Beccari G, Powell J, Yamashino T, Kogler H, Sondergaard TE, Gardiner DM.

Mol Plant Pathol. 2018 May;19(5):1140-1154. doi: 10.1111/mpp.12593. Epub 2017 Oct 24.

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