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Items: 14


Verapamil Targets Membrane Energetics in Mycobacterium tuberculosis.

Chen C, Gardete S, Jansen RS, Shetty A, Dick T, Rhee KY, Dartois V.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02107-17. doi: 10.1128/AAC.02107-17. Print 2018 May.


Metabolic Perspectives on Persistence.

Hartman TE, Wang Z, Jansen RS, Gardete S, Rhee KY.

Microbiol Spectr. 2017 Jan;5(1). doi: 10.1128/microbiolspec.TBTB2-0026-2016. Review.


Mechanisms of vancomycin resistance in Staphylococcus aureus.

Gardete S, Tomasz A.

J Clin Invest. 2014 Jul;124(7):2836-40. doi: 10.1172/JCI68834. Epub 2014 Jul 1. Review.


Intermediate-type vancomycin resistance (VISA) in genetically-distinct Staphylococcus aureus isolates is linked to specific, reversible metabolic alterations.

Alexander EL, Gardete S, Bar HY, Wells MT, Tomasz A, Rhee KY.

PLoS One. 2014 May 9;9(5):e97137. doi: 10.1371/journal.pone.0097137. eCollection 2014.


Alternative mutational pathways to intermediate resistance to vancomycin in methicillin-resistant Staphylococcus aureus.

Vidaillac C, Gardete S, Tewhey R, Sakoulas G, Kaatz GW, Rose WE, Tomasz A, Rybak MJ.

J Infect Dis. 2013 Jul;208(1):67-74. doi: 10.1093/infdis/jit127. Epub 2013 Mar 28.


Properties of a novel PBP2A protein homolog from Staphylococcus aureus strain LGA251 and its contribution to the ╬▓-lactam-resistant phenotype.

Kim C, Milheiri├žo C, Gardete S, Holmes MA, Holden MT, de Lencastre H, Tomasz A.

J Biol Chem. 2012 Oct 26;287(44):36854-63. doi: 10.1074/jbc.M112.395962. Epub 2012 Sep 12.


Genetic pathway in acquisition and loss of vancomycin resistance in a methicillin resistant Staphylococcus aureus (MRSA) strain of clonal type USA300.

Gardete S, Kim C, Hartmann BM, Mwangi M, Roux CM, Dunman PM, Chambers HF, Tomasz A.

PLoS Pathog. 2012 Feb;8(2):e1002505. doi: 10.1371/journal.ppat.1002505. Epub 2012 Feb 2.


Evolution of MRSA during hospital transmission and intercontinental spread.

Harris SR, Feil EJ, Holden MT, Quail MA, Nickerson EK, Chantratita N, Gardete S, Tavares A, Day N, Lindsay JA, Edgeworth JD, de Lencastre H, Parkhill J, Peacock SJ, Bentley SD.

Science. 2010 Jan 22;327(5964):469-74. doi: 10.1126/science.1182395.


Identification of the first vancomycin intermediate-resistant Staphylococcus aureus (VISA) isolate from a hospital in Portugal.

Gardete S, Aires-De-Sousa M, Faustino A, Ludovice AM, de Lencastre H.

Microb Drug Resist. 2008 Mar;14(1):1-6. doi: 10.1089/mdr.2008.0816.


Role of VraSR in antibiotic resistance and antibiotic-induced stress response in Staphylococcus aureus.

Gardete S, Wu SW, Gill S, Tomasz A.

Antimicrob Agents Chemother. 2006 Oct;50(10):3424-34.


A link in transcription between the native pbpB and the acquired mecA gene in a strain of Staphylococcus aureus.

Gardete S, de Lencastre H, Tomasz A.

Microbiology. 2006 Sep;152(Pt 9):2549-58.


Role of murE in the Expression of beta-lactam antibiotic resistance in Staphylococcus aureus.

Gardete S, Ludovice AM, Sobral RG, Filipe SR, de Lencastre H, Tomasz A.

J Bacteriol. 2004 Mar;186(6):1705-13.


Normally functioning murF is essential for the optimal expression of methicillin resistance in Staphylococcus aureus.

Sobral RG, Ludovice AM, Gardete S, Tabei K, De Lencastre H, Tomasz A.

Microb Drug Resist. 2003 Fall;9(3):231-41.


Antibiotic resistance as a stress response: complete sequencing of a large number of chromosomal loci in Staphylococcus aureus strain COL that impact on the expression of resistance to methicillin.

De Lencastre H, Wu SW, Pinho MG, Ludovice AM, Filipe S, Gardete S, Sobral R, Gill S, Chung M, Tomasz A.

Microb Drug Resist. 1999 Fall;5(3):163-75.


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