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Items: 18

1.

Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase-Activating Peptide.

Moldovan Loomis C, Dutzar B, Ojala EW, Hendrix L, Karasek C, Scalley-Kim M, Mulligan J, Fan P, Billgren J, Rubin V, Boshaw H, Kwon G, Marzolf S, Stewart E, Jurchen D, Pederson SM, Perrino McCulloch L, Baker B, Cady RK, Latham JA, Allison D, Garcia-Martinez LF.

J Pharmacol Exp Ther. 2019 Apr;369(1):26-36. doi: 10.1124/jpet.118.253443. Epub 2019 Jan 14.

PMID:
30643015
2.

Peripherally administered calcitonin gene-related peptide induces spontaneous pain in mice: implications for migraine.

Rea BJ, Wattiez AS, Waite JS, Castonguay WC, Schmidt CM, Fairbanks AM, Robertson BR, Brown CJ, Mason BN, Moldovan-Loomis MC, Garcia-Martinez LF, Poolman P, Ledolter J, Kardon RH, Sowers LP, Russo AF.

Pain. 2018 Nov;159(11):2306-2317. doi: 10.1097/j.pain.0000000000001337.

PMID:
29994995
3.

Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms.

Mason BN, Kaiser EA, Kuburas A, Loomis MM, Latham JA, Garcia-Martinez LF, Russo AF.

J Neurosci. 2017 Jan 4;37(1):204-216. doi: 10.1523/JNEUROSCI.2967-16.2016.

4.

ALD1613, a Novel Long-Acting Monoclonal Antibody to Control ACTH-Driven Pharmacology.

Feldhaus AL, Anderson K, Dutzar B, Ojala E, McNeill PD, Fan P, Mulligan J, Marzolf S, Karasek C, Scalley-Kim M, Stewart E, Billgren J, Rubin V, Schneider K, Jurchen D, Snow K, Barnett S, Bengtsson B, Baker B, Latham JA, Allison D, Garcia-Martinez LF.

Endocrinology. 2017 Jan 1;158(1):1-8. doi: 10.1210/en.2016-1455.

PMID:
27906551
5.

Anti-CGRP antibodies block CGRP-induced diarrhea in mice.

Kaiser EA, Rea BJ, Kuburas A, Kovacevich BR, Garcia-Martinez LF, Recober A, Russo AF.

Neuropeptides. 2017 Aug;64:95-99. doi: 10.1016/j.npep.2016.11.004. Epub 2016 Nov 14.

6.

CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity.

Sadhu C, Ting HJ, Lipsky B, Hensley K, Garcia-Martinez LF, Simon SI, Staunton DE.

J Leukoc Biol. 2007 Jun;81(6):1395-403. Epub 2007 Mar 27.

PMID:
17389580
7.

A novel mutation in CD83 results in the development of a unique population of CD4+ T cells.

García-Martínez LF, Appleby MW, Staehling-Hampton K, Andrews DM, Chen Y, McEuen M, Tang P, Rhinehart RL, Proll S, Paeper B, Brunkow ME, Grandea AG 3rd, Howard ED, Walker DE, Charmley P, Jonas M, Shaw S, Latham JA, Ramsdell F.

J Immunol. 2004 Sep 1;173(5):2995-3001.

8.

In vitro high-throughput screening assay for modulators of transcription.

García-Martínez LF, Bilter GK, Wu J, O'Neill J, Barbosa MS, Kovelman R.

Anal Biochem. 2002 Feb 1;301(1):103-10.

PMID:
11811973
9.

Cyclin T1 domains involved in complex formation with Tat and TAR RNA are critical for tat-activation.

Ivanov D, Kwak YT, Nee E, Guo J, García-Martínez LF, Gaynor RB.

J Mol Biol. 1999 Apr 23;288(1):41-56.

PMID:
10329125
10.

DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties.

Liu L, Kwak YT, Bex F, García-Martínez LF, Li XH, Meek K, Lane WS, Gaynor RB.

Mol Cell Biol. 1998 Jul;18(7):4221-34.

11.

Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription.

García-Martínez LF, Mavankal G, Neveu JM, Lane WS, Ivanov D, Gaynor RB.

EMBO J. 1997 May 15;16(10):2836-50.

12.

Tat is required for efficient HIV-1 reverse transcription.

Harrich D, Ulich C, García-Martínez LF, Gaynor RB.

EMBO J. 1997 Mar 17;16(6):1224-35.

13.

Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes.

García-Martínez LF, Ivanov D, Gaynor RB.

J Biol Chem. 1997 Mar 14;272(11):6951-8.

14.

Purification and functional characterization of wild-type and mutant HIV-1 and HIV-2 Tat proteins expressed in Escherichia coli.

Orsini MJ, García-Martínez LF, Mavankal G, Gaynor RB, Debouck CM.

Protein Expr Purif. 1996 Sep;8(2):238-46.

PMID:
8812870
15.

Tat functions to stimulate the elongation properties of transcription complexes paused by the duplicated TAR RNA element of human immunodeficiency virus 2.

García-Martínez LF, Mavankal G, Peters P, Wu-Baer F, Gaynor RB.

J Mol Biol. 1995 Dec 1;254(3):350-63.

PMID:
7490754
16.
17.

Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function.

Ou SH, Garcia-Martínez LF, Paulssen EJ, Gaynor RB.

J Virol. 1994 Nov;68(11):7188-99.

18.

Characterization of the folate-dependent mitochondrial oxidation of carbon 3 of serine.

García-Martínez LF, Appling DR.

Biochemistry. 1993 May 4;32(17):4671-6.

PMID:
8485144

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