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Items: 1 to 50 of 67

1.

Antifungal activity and killing kinetics of anidulafungin, caspofungin and amphotericin B against Candida auris.

Dudiuk C, Berrio I, Leonardelli F, Morales-Lopez S, Theill L, Macedo D, Yesid-Rodriguez J, Salcedo S, Marin A, Gamarra S, Garcia-Effron G.

J Antimicrob Chemother. 2019 May 12. pii: dkz178. doi: 10.1093/jac/dkz178. [Epub ahead of print]

PMID:
31081031
2.

In Vitro Activity of Combinations of Zinc Chelators with Amphotericin B and Posaconazole against Six Mucorales Species.

Leonardelli F, Macedo D, Dudiuk C, Theill L, Cabeza MS, Gamarra S, Garcia-Effron G.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00266-19. doi: 10.1128/AAC.00266-19. Print 2019 May.

PMID:
30885898
3.

In Vitro and In Vivo Evaluation of Voriconazole-Containing Antifungal Combinations against Mucorales Using a Galleria mellonella Model of Mucormycosis.

Macedo D, Leonardelli F, Dudiuk C, Vitale RG, Del Valle E, Giusiano G, Gamarra S, Garcia-Effron G.

J Fungi (Basel). 2019 Jan 8;5(1). pii: E5. doi: 10.3390/jof5010005.

4.

Method-Dependent Epidemiological Cutoff Values for Detection of Triazole Resistance in Candida and Aspergillus Species for the Sensititre YeastOne Colorimetric Broth and Etest Agar Diffusion Methods.

Espinel-Ingroff A, Turnidge J, Alastruey-Izquierdo A, Botterel F, Canton E, Castro C, Chen YC, Chen Y, Chryssanthou E, Dannaoui E, Garcia-Effron G, Gonzalez GM, Govender NP, Guinea J, Kidd S, Lackner M, Lass-Flörl C, Linares-Sicilia MJ, López-Soria L, Magobo R, Pelaez T, Quindós G, Rodriguez-Iglesia MA, Ruiz MA, Sánchez-Reus F, Sanguinetti M, Shields R, Szweda P, Tortorano A, Wengenack NL, Bramati S, Cavanna C, DeLuca C, Gelmi M, Grancini A, Lombardi G, Meletiadis J, Negri CE, Passera M, Peman J, Prigitano A, Sala E, Tejada M.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01651-18. doi: 10.1128/AAC.01651-18. Print 2019 Jan.

5.

Mucormycosis outbreak due to Rhizopus microsporus after arthroscopic anterior cruciate ligament reconstruction surgery evaluated by RAPD and MALDI-TOF Mass spectrometry.

Gamarra S, Chaves MS, Cabeza MS, Macedo D, Leonardelli F, Franco D, Boleas M, Garcia-Effron G.

J Mycol Med. 2018 Dec;28(4):617-622. doi: 10.1016/j.mycmed.2018.09.002. Epub 2018 Sep 22.

PMID:
30249460
6.

First Clinical Isolation of an Azole-Resistant Aspergillus fumigatus Isolate Harboring a TR46 Y121F T289A Mutation in South America.

Isla G, Leonardelli F, Tiraboschi IN, Refojo N, Hevia A, Vivot W, Szusz W, Córdoba SB, García-Effron G.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e00872-18. doi: 10.1128/AAC.00872-18. Print 2018 Oct.

7.

Molecular Confirmation of the Linkage between the Rhizopus oryzae CYP51A Gene Coding Region and Its Intrinsic Voriconazole and Fluconazole Resistance.

Macedo D, Leonardelli F, Dudiuk C, Theill L, Cabeza MS, Gamarra S, Garcia-Effron G.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00224-18. doi: 10.1128/AAC.00224-18. Print 2018 Aug.

8.

Single-tube classical PCR for Candida auris and Candida haemulonii identification.

Theill L, Dudiuk C, Morales-Lopez S, Berrio I, Rodríguez JY, Marin A, Gamarra S, Garcia-Effron G.

Rev Iberoam Micol. 2018 Apr - Jun;35(2):110-112. doi: 10.1016/j.riam.2018.01.003. Epub 2018 Apr 21.

PMID:
29685376
9.

Posaconazole MIC Distributions for Aspergillus fumigatus Species Complex by Four Methods: Impact of cyp51A Mutations on Estimation of Epidemiological Cutoff Values.

Espinel-Ingroff A, Turnidge J, Alastruey-Izquierdo A, Dannaoui E, Garcia-Effron G, Guinea J, Kidd S, Pelaez T, Sanguinetti M, Meletiadis J, Botterel F, Bustamante B, Chen YC, Chakrabarti A, Chowdhary A, Chryssanthou E, Córdoba S, Gonzalez GM, Guarro J, Johnson EM, Kus JV, Lass-Flörl C, Linares-Sicilia MJ, Martín-Mazuelos E, Negri CE, Pfaller MA, Tortorano AM.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e01916-17. doi: 10.1128/AAC.01916-17. Print 2018 Apr.

10.

Identification of Candida parapsilosis Sensu Lato in Pediatric Patients and Antifungal Susceptibility Testing.

Cattana ME, Dudiuk C, Fernández M, Rojas F, Alegre L, Córdoba S, Garcia-Effron G, Giusiano G.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e02754-16. doi: 10.1128/AAC.02754-16. Print 2017 Jul.

11.

Phenotypic and Molecular Evaluation of Echinocandin Susceptibility of Candida glabrata, Candida bracarensis, and Candida nivariensis Strains Isolated during 30 Years in Argentina.

Morales-López S, Dudiuk C, Vivot W, Szusz W, Córdoba SB, Garcia-Effron G.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00170-17. doi: 10.1128/AAC.00170-17. Print 2017 Jul.

12.

Molecular Confirmation of the Relationship between Candida guilliermondii Fks1p Naturally Occurring Amino Acid Substitutions and Its Intrinsic Reduced Echinocandin Susceptibility.

Dudiuk C, Macedo D, Leonardelli F, Theill L, Cabeza MS, Gamarra S, Garcia-Effron G.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02644-16. doi: 10.1128/AAC.02644-16. Print 2017 May.

13.

First itraconazole resistant Aspergillus fumigatus clinical isolate harbouring a G54E substitution in Cyp51Ap in South America.

Leonardelli F, Theill L, Nardin ME, Macedo D, Dudiuk C, Mendez E, Gamarra S, Garcia-Effron G.

Rev Iberoam Micol. 2017 Jan - Mar;34(1):46-48. doi: 10.1016/j.riam.2016.05.005. Epub 2017 Jan 10.

PMID:
28087293
14.

Multiplex PCR designed to differentiate species within the Candida glabrata complex.

Dudiuk C, Morales-López SE, Podesta V, Macedo D, Leonardelli F, Vitale RG, Tosello ME, Cabeza MS, Biasoli M, Gamarra S, Garcia-Effron G.

Rev Iberoam Micol. 2017 Jan - Mar;34(1):43-45. doi: 10.1016/j.riam.2016.04.007. Epub 2016 Oct 31.

PMID:
27810263
15.

Multicenter Study of Method-Dependent Epidemiological Cutoff Values for Detection of Resistance in Candida spp. and Aspergillus spp. to Amphotericin B and Echinocandins for the Etest Agar Diffusion Method.

Espinel-Ingroff A, Arendrup M, Cantón E, Cordoba S, Dannaoui E, García-Rodríguez J, Gonzalez GM, Govender NP, Martin-Mazuelos E, Lackner M, Lass-Flörl C, Linares Sicilia MJ, Rodriguez-Iglesias MA, Pelaez T, Shields RK, Garcia-Effron G, Guinea J, Sanguinetti M, Turnidge J.

Antimicrob Agents Chemother. 2016 Dec 27;61(1). pii: e01792-16. doi: 10.1128/AAC.01792-16. Print 2017 Jan.

16.

Candida glabrata species complex prevalence and antifungal susceptibility testing in a culture collection: First description of Candida nivariensis in Argentina.

Morales-López SE, Taverna CG, Bosco-Borgeat ME, Maldonado I, Vivot W, Szusz W, Garcia-Effron G, Córdoba SB.

Mycopathologia. 2016 Dec;181(11-12):871-878. Epub 2016 Sep 28.

PMID:
27681573
17.

Control of an outbreak of postoperative bone mucormycosis: An intervention study of contiguous cohorts.

Chaves MS, Franco D, Nanni JC, Basaldúa ML, Boleas M, Aphalo G, Feltes Silva P, Elgadban MC, Emery F, Gamarra S, Garcia-Effron G, Bantar C.

Am J Infect Control. 2016 Dec 1;44(12):1715-1717. doi: 10.1016/j.ajic.2016.06.017. Epub 2016 Aug 4.

PMID:
27499195
18.

Aspergillus fumigatus Intrinsic Fluconazole Resistance Is Due to the Naturally Occurring T301I Substitution in Cyp51Ap.

Leonardelli F, Macedo D, Dudiuk C, Cabeza MS, Gamarra S, Garcia-Effron G.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5420-6. doi: 10.1128/AAC.00905-16. Print 2016 Sep.

19.

Prevalence and antifungal susceptibility of Candida albicans and its related species Candida dubliniensis and Candida africana isolated from vulvovaginal samples in a hospital of Argentina.

Theill L, Dudiuk C, Morano S, Gamarra S, Nardin ME, Méndez E, Garcia-Effron G.

Rev Argent Microbiol. 2016 Jan-Mar;48(1):43-9. doi: 10.1016/j.ram.2015.10.003. Epub 2016 Feb 26.

20.

Identification of Brucella ovis exclusive genes in field isolates from Argentina.

Alvarez LP, García-Effrón G, Robles CA.

Vet J. 2016 Mar;209:196-8. doi: 10.1016/j.tvjl.2015.12.005. Epub 2015 Dec 17.

PMID:
26831160
21.

Multicenter study of epidemiological cutoff values and detection of resistance in Candida spp. to anidulafungin, caspofungin, and micafungin using the Sensititre YeastOne colorimetric method.

Espinel-Ingroff A, Alvarez-Fernandez M, Cantón E, Carver PL, Chen SC, Eschenauer G, Getsinger DL, Gonzalez GM, Govender NP, Grancini A, Hanson KE, Kidd SE, Klinker K, Kubin CJ, Kus JV, Lockhart SR, Meletiadis J, Morris AJ, Pelaez T, Quindós G, Rodriguez-Iglesias M, Sánchez-Reus F, Shoham S, Wengenack NL, Borrell Solé N, Echeverria J, Esperalba J, Gómez-G de la Pedrosa E, García García I, Linares MJ, Marco F, Merino P, Pemán J, Pérez Del Molino L, Roselló Mayans E, Rubio Calvo C, Ruiz Pérez de Pipaon M, Yagüe G, Garcia-Effron G, Guinea J, Perlin DS, Sanguinetti M, Shields R, Turnidge J.

Antimicrob Agents Chemother. 2015 Nov;59(11):6725-32. doi: 10.1128/AAC.01250-15. Epub 2015 Aug 17.

22.

Quick Detection of FKS1 Mutations Responsible for Clinical Echinocandin Resistance in Candida albicans.

Dudiuk C, Gamarra S, Jimenez-Ortigosa C, Leonardelli F, Macedo D, Perlin DS, Garcia-Effron G.

J Clin Microbiol. 2015 Jul;53(7):2037-41. doi: 10.1128/JCM.00398-15. Epub 2015 Apr 15.

23.

Candida dubliniensis and Candida albicans differentiation by colony morphotype in Sabouraud-triphenyltetrazolium agar.

Gamarra S, Mancilla E, Dudiuk C, Garcia-Effron G.

Rev Iberoam Micol. 2015 Apr-Jun;32(2):126-8. doi: 10.1016/j.riam.2014.02.002. Epub 2014 Aug 29.

PMID:
25613786
24.

Epidemiology and antifungal susceptibilities of yeasts causing vulvovaginitis in a teaching hospital.

Gamarra S, Morano S, Dudiuk C, Mancilla E, Nardin ME, de Los Angeles Méndez E, Garcia-Effron G.

Mycopathologia. 2014 Oct;178(3-4):251-8. doi: 10.1007/s11046-014-9780-2. Epub 2014 Jul 9.

PMID:
25005365
25.

Set of classical PCRs for detection of mutations in Candida glabrata FKS genes linked with echinocandin resistance.

Dudiuk C, Gamarra S, Leonardeli F, Jimenez-Ortigosa C, Vitale RG, Afeltra J, Perlin DS, Garcia-Effron G.

J Clin Microbiol. 2014 Jul;52(7):2609-14. doi: 10.1128/JCM.01038-14. Epub 2014 May 14.

26.

Isavuconazole activity against Aspergillus lentulus, Neosartorya udagawae, and Cryptococcus gattii, emerging fungal pathogens with reduced azole susceptibility.

Datta K, Rhee P, Byrnes E 3rd, Garcia-Effron G, Perlin DS, Staab JF, Marr KA.

J Clin Microbiol. 2013 Sep;51(9):3090-3. doi: 10.1128/JCM.01190-13. Epub 2013 Jun 26.

27.

Molecular tools for cryptic Candida species identification with applications in a clinical laboratory.

Gamarra S, Dudiuk C, Mancilla E, Vera Garate MV, Guerrero S, Garcia-Effron G.

Biochem Mol Biol Educ. 2013 May-Jun;41(3):180-6. doi: 10.1002/bmb.20692. Epub 2013 Apr 27.

28.

Epidemiology and echinocandin susceptibility of Candida parapsilosis sensu lato species isolated from bloodstream infections at a Spanish university hospital.

Garcia-Effron G, Canton E, Pemán J, Dilger A, Romá E, Perlin DS.

J Antimicrob Chemother. 2012 Nov;67(11):2739-48. doi: 10.1093/jac/dks271. Epub 2012 Aug 6.

29.

Evaluation of fungal-specific fluorescent labeled echinocandin probes as diagnostic adjuncts.

Pratt A, Garcia-Effron G, Zhao Y, Park S, Mustaev A, Pillai S, Perlin DS.

Med Mycol. 2013 Jan;51(1):103-7. doi: 10.3109/13693786.2012.685767. Epub 2012 May 15.

PMID:
22587729
30.

Assessment of two new molecular methods for identification of Candida parapsilosis sensu lato species.

Garcia-Effron G, Canton E, Pemán J, Dilger A, Romá E, Perlin DS.

J Clin Microbiol. 2011 Sep;49(9):3257-61. doi: 10.1128/JCM.00508-11. Epub 2011 Jul 27.

31.

Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance.

Ben-Ami R, Garcia-Effron G, Lewis RE, Gamarra S, Leventakos K, Perlin DS, Kontoyiannis DP.

J Infect Dis. 2011 Aug 15;204(4):626-35. doi: 10.1093/infdis/jir351.

32.

Improved detection of Candida sp. fks hot spot mutants by using the method of the CLSI M27-A3 document with the addition of bovine serum albumin.

Garcia-Effron G, Park S, Perlin DS.

Antimicrob Agents Chemother. 2011 May;55(5):2245-55. doi: 10.1128/AAC.01350-10. Epub 2011 Mar 7.

33.

Echinocandin susceptibility testing of Candida spp. Using EUCAST EDef 7.1 and CLSI M27-A3 standard procedures: analysis of the influence of bovine serum albumin supplementation, storage time, and drug lots.

Arendrup MC, Rodriguez-Tudela JL, Park S, Garcia-Effron G, Delmas G, Cuenca-Estrella M, Gomez-Lopez A, Perlin DS.

Antimicrob Agents Chemother. 2011 Apr;55(4):1580-7. doi: 10.1128/AAC.01364-10. Epub 2011 Jan 18.

34.

Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs.

Zhang YQ, Gamarra S, Garcia-Effron G, Park S, Perlin DS, Rao R.

PLoS Pathog. 2010 Jun 3;6(6):e1000939. doi: 10.1371/journal.ppat.1000939.

35.

Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose.

Rodriguez-Tudela JL, Gomez-Lopez A, Arendrup MC, Garcia-Effron G, Perlin DS, Lass-Flörl C, Cuenca-Estrella M.

Antimicrob Agents Chemother. 2010 Jul;54(7):3056-7. doi: 10.1128/AAC.00597-10. Epub 2010 May 17.

36.

Breakthrough invasive candidiasis in patients on micafungin.

Pfeiffer CD, Garcia-Effron G, Zaas AK, Perfect JR, Perlin DS, Alexander BD.

J Clin Microbiol. 2010 Jul;48(7):2373-80. doi: 10.1128/JCM.02390-09. Epub 2010 Apr 26.

37.

Novel FKS mutations associated with echinocandin resistance in Candida species.

Garcia-Effron G, Chua DJ, Tomada JR, DiPersio J, Perlin DS, Ghannoum M, Bonilla H.

Antimicrob Agents Chemother. 2010 May;54(5):2225-7. doi: 10.1128/AAC.00998-09. Epub 2010 Feb 9.

38.

beta-Thalassaemia Major in a Spanish Patient due to a Compound Heterozygosity for CD39 C --> T/-28 A --> C.

Gamarra S, Garcia-Effron G, Monteserin C, Lopez-Villar I, Gilsanz F, Martinez-Lopez J.

Adv Hematol. 2009;2009:476342. doi: 10.1155/2009/476342. Epub 2009 Jul 28.

39.

Echinocandin susceptibility testing of Candida species: comparison of EUCAST EDef 7.1, CLSI M27-A3, Etest, disk diffusion, and agar dilution methods with RPMI and isosensitest media.

Arendrup MC, Garcia-Effron G, Lass-Flörl C, Lopez AG, Rodriguez-Tudela JL, Cuenca-Estrella M, Perlin DS.

Antimicrob Agents Chemother. 2010 Jan;54(1):426-39. doi: 10.1128/AAC.01256-09. Epub 2009 Nov 2.

40.

Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint.

Garcia-Effron G, Lee S, Park S, Cleary JD, Perlin DS.

Antimicrob Agents Chemother. 2009 Sep;53(9):3690-9. doi: 10.1128/AAC.00443-09. Epub 2009 Jun 22.

41.

Breakthrough Aspergillus fumigatus and Candida albicans double infection during caspofungin treatment: laboratory characteristics and implication for susceptibility testing.

Arendrup MC, Garcia-Effron G, Buzina W, Mortensen KL, Reiter N, Lundin C, Jensen HE, Lass-Flörl C, Perlin DS, Bruun B.

Antimicrob Agents Chemother. 2009 Mar;53(3):1185-93. doi: 10.1128/AAC.01292-08. Epub 2008 Dec 22.

42.

Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: implications for interpretive breakpoints.

Garcia-Effron G, Park S, Perlin DS.

Antimicrob Agents Chemother. 2009 Jan;53(1):112-22. doi: 10.1128/AAC.01162-08. Epub 2008 Oct 27.

43.

Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic malignancies.

Garcia-Effron G, Kontoyiannis DP, Lewis RE, Perlin DS.

Antimicrob Agents Chemother. 2008 Nov;52(11):4181-3. doi: 10.1128/AAC.00802-08. Epub 2008 Sep 15.

44.

Pyrosequencing to detect mutations in FKS1 that confer reduced echinocandin susceptibility in Candida albicans.

Wiederhold NP, Grabinski JL, Garcia-Effron G, Perlin DS, Lee SA.

Antimicrob Agents Chemother. 2008 Nov;52(11):4145-8. doi: 10.1128/AAC.00959-08. Epub 2008 Sep 15.

45.

Establishing in vitro-in vivo correlations for Aspergillus fumigatus: the challenge of azoles versus echinocandins.

Arendrup MC, Perkhofer S, Howard SJ, Garcia-Effron G, Vishukumar A, Perlin D, Lass-Flörl C.

Antimicrob Agents Chemother. 2008 Oct;52(10):3504-11. doi: 10.1128/AAC.00190-08. Epub 2008 Jul 21.

46.

A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility.

Garcia-Effron G, Katiyar SK, Park S, Edlind TD, Perlin DS.

Antimicrob Agents Chemother. 2008 Jul;52(7):2305-12. doi: 10.1128/AAC.00262-08. Epub 2008 Apr 28.

47.

Reduced Candida glabrata susceptibility secondary to an FKS1 mutation developed during candidemia treatment.

Cleary JD, Garcia-Effron G, Chapman SW, Perlin DS.

Antimicrob Agents Chemother. 2008 Jun;52(6):2263-5. doi: 10.1128/AAC.01568-07. Epub 2008 Mar 31.

48.

Rapid detection of triazole antifungal resistance in Aspergillus fumigatus.

Garcia-Effron G, Dilger A, Alcazar-Fuoli L, Park S, Mellado E, Perlin DS.

J Clin Microbiol. 2008 Apr;46(4):1200-6. doi: 10.1128/JCM.02330-07. Epub 2008 Jan 30.

49.

Ergosterol biosynthesis pathway in Aspergillus fumigatus.

Alcazar-Fuoli L, Mellado E, Garcia-Effron G, Lopez JF, Grimalt JO, Cuenca-Estrella JM, Rodriguez-Tudela JL.

Steroids. 2008 Mar;73(3):339-47. doi: 10.1016/j.steroids.2007.11.005. Epub 2007 Dec 3.

PMID:
18191972
50.

A Ser678Pro substitution in Fks1p confers resistance to echinocandin drugs in Aspergillus fumigatus.

Rocha EM, Garcia-Effron G, Park S, Perlin DS.

Antimicrob Agents Chemother. 2007 Nov;51(11):4174-6. Epub 2007 Aug 27.

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