Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 11

1.

Target identification reveals lanosterol synthase as a vulnerability in glioma.

Phillips RE, Yang Y, Smith RC, Thompson BM, Yamasaki T, Soto-Feliciano YM, Funato K, Liang Y, Garcia-Bermudez J, Wang X, Garcia BA, Yamasaki K, McDonald JG, Birsoy K, Tabar V, Allis CD.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7957-7962. doi: 10.1073/pnas.1820989116. Epub 2019 Mar 28.

PMID:
30923116
2.

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.

Garcia-Bermudez J, Baudrier L, Bayraktar EC, Shen Y, La K, Guarecuco R, Yucel B, Fiore D, Tavora B, Freinkman E, Chan SH, Lewis C, Min W, Inghirami G, Sabatini DM, Birsoy K.

Nature. 2019 Mar;567(7746):118-122. doi: 10.1038/s41586-019-0945-5. Epub 2019 Feb 13.

PMID:
30760928
3.

Publisher Correction: Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours.

Garcia-Bermudez J, Baudrier L, La K, Zhu XG, Fidelin J, Sviderskiy VO, Papagiannakopoulos T, Molina H, Snuderl M, Lewis CA, Possemato RL, Birsoy K.

Nat Cell Biol. 2018 Oct;20(10):1228. doi: 10.1038/s41556-018-0184-2.

PMID:
30089842
4.

Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours.

Garcia-Bermudez J, Baudrier L, La K, Zhu XG, Fidelin J, Sviderskiy VO, Papagiannakopoulos T, Molina H, Snuderl M, Lewis CA, Possemato RL, Birsoy K.

Nat Cell Biol. 2018 Jul;20(7):775-781. doi: 10.1038/s41556-018-0118-z. Epub 2018 Jun 25. Erratum in: Nat Cell Biol. 2018 Oct;20(10):1228.

5.

Drugging ACAT1 for Cancer Therapy.

Garcia-Bermudez J, Birsoy K.

Mol Cell. 2016 Dec 1;64(5):856-857. doi: 10.1016/j.molcel.2016.11.023.

6.

The ATPase Inhibitory Factor 1 (IF1): A master regulator of energy metabolism and of cell survival.

García-Bermúdez J, Cuezva JM.

Biochim Biophys Acta. 2016 Aug;1857(8):1167-1182. doi: 10.1016/j.bbabio.2016.02.004. Epub 2016 Feb 12.

7.

Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state.

Santacatterina F, Sánchez-Cenizo L, Formentini L, Mobasher MA, Casas E, Rueda CB, Martínez-Reyes I, Núñez de Arenas C, García-Bermúdez J, Zapata JM, Sánchez-Aragó M, Satrústegui J, Valverde ÁM, Cuezva JM.

Oncotarget. 2016 Jan 5;7(1):490-508. doi: 10.18632/oncotarget.6357.

8.

PKA Phosphorylates the ATPase Inhibitory Factor 1 and Inactivates Its Capacity to Bind and Inhibit the Mitochondrial H(+)-ATP Synthase.

García-Bermúdez J, Sánchez-Aragó M, Soldevilla B, Del Arco A, Nuevo-Tapioles C, Cuezva JM.

Cell Rep. 2015 Sep 29;12(12):2143-55. doi: 10.1016/j.celrep.2015.08.052. Epub 2015 Sep 17.

9.

Degradation of IF1 controls energy metabolism during osteogenic differentiation of stem cells.

Sánchez-Aragó M, García-Bermúdez J, Martínez-Reyes I, Santacatterina F, Cuezva JM.

EMBO Rep. 2013 Jul;14(7):638-44. doi: 10.1038/embor.2013.72. Epub 2013 May 31.

10.

Expression, regulation and clinical relevance of the ATPase inhibitory factor 1 in human cancers.

Sánchez-Aragó M, Formentini L, Martínez-Reyes I, García-Bermudez J, Santacatterina F, Sánchez-Cenizo L, Willers IM, Aldea M, Nájera L, Juarránz A, López EC, Clofent J, Navarro C, Espinosa E, Cuezva JM.

Oncogenesis. 2013 Apr 22;2:e46. doi: 10.1038/oncsis.2013.9.

11.

IF1 reprograms energy metabolism and signals the oncogenic phenotype in cancer.

Sánchez-Aragó M, Formentini L, García-Bermúdez J, Cuezva JM.

Cell Cycle. 2012 Aug 15;11(16):2963-4. doi: 10.4161/cc.21387. Epub 2012 Aug 8. No abstract available.

Supplemental Content

Loading ...
Support Center