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Items: 20

1.

AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells.

Coant N, García-Barros M, Zhang Q, Obeid LM, Hannun YA.

Oncogene. 2018 Jul;37(28):3852-3863. doi: 10.1038/s41388-018-0236-x. Epub 2018 Apr 17.

2.

Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates.

Li F, Xu R, Low BE, Lin CL, Garcia-Barros M, Schrandt J, Mileva I, Snider A, Luo CK, Jiang XC, Li MS, Hannun YA, Obeid LM, Wiles MV, Mao C.

FASEB J. 2018 Jun;32(6):3058-3069. doi: 10.1096/fj.201700445RR. Epub 2018 Jan 22.

3.

Tumor suppressor p53 links ceramide metabolism to DNA damage response through alkaline ceramidase 2.

Xu R, Garcia-Barros M, Wen S, Li F, Lin CL, Hannun YA, Obeid LM, Mao C.

Cell Death Differ. 2018 May;25(5):841-856. doi: 10.1038/s41418-017-0018-y. Epub 2017 Dec 11.

4.

Targeting acid sphingomyelinase with anti-angiogenic chemotherapy.

Jacobi J, García-Barros M, Rao S, Rotolo JA, Thompson C, Mizrachi A, Feldman R, Manova K, Bielawska A, Bielawska J, Fuks Z, Kolesnick R, Haimovitz-Friedman A.

Cell Signal. 2017 Jan;29:52-61. doi: 10.1016/j.cellsig.2016.09.010. Epub 2016 Oct 1.

5.

Role of neutral ceramidase in colon cancer.

García-Barros M, Coant N, Kawamori T, Wada M, Snider AJ, Truman JP, Wu BX, Furuya H, Clarke CJ, Bialkowska AB, Ghaleb A, Yang VW, Obeid LM, Hannun YA.

FASEB J. 2016 Dec;30(12):4159-4171. Epub 2016 Sep 8.

6.

ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer.

Ruiz de Sabando A, Wang C, He Y, García-Barros M, Kim J, Shroyer KR, Bannister TD, Yang VW, Bialkowska AB.

Mol Cancer Ther. 2016 Jan;15(1):72-83. doi: 10.1158/1535-7163.MCT-15-0600. Epub 2015 Nov 30.

7.

Evolving concepts in cancer therapy through targeting sphingolipid metabolism.

Truman JP, García-Barros M, Obeid LM, Hannun YA.

Biochim Biophys Acta. 2014 Aug;1841(8):1174-88. doi: 10.1016/j.bbalip.2013.12.013. Epub 2013 Dec 30. Review.

8.

Sphingolipids in colon cancer.

García-Barros M, Coant N, Truman JP, Snider AJ, Hannun YA.

Biochim Biophys Acta. 2014 May;1841(5):773-82. doi: 10.1016/j.bbalip.2013.09.007. Epub 2013 Sep 21. Review.

9.

Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure.

Stancevic B, Varda-Bloom N, Cheng J, Fuller JD, Rotolo JA, García-Barros M, Feldman R, Rao S, Weichselbaum RR, Harats D, Haimovitz-Friedman A, Fuks Z, Sadelain M, Kolesnick R.

PLoS One. 2013 Aug 2;8(8):e69025. doi: 10.1371/journal.pone.0069025. Print 2013.

10.

Endothelial membrane remodeling is obligate for anti-angiogenic radiosensitization during tumor radiosurgery.

Truman JP, García-Barros M, Kaag M, Hambardzumyan D, Stancevic B, Chan M, Fuks Z, Kolesnick R, Haimovitz-Friedman A.

PLoS One. 2010 Sep 30;5(9). doi: 10.1371/annotation/6e222ad5-b175-4a00-9d04-4d120568a897.

11.

Impact of stromal sensitivity on radiation response of tumors implanted in SCID hosts revisited.

García-Barros M, Thin TH, Maj J, Cordon-Cardo C, Haimovitz-Friedman A, Fuks Z, Kolesnick R.

Cancer Res. 2010 Oct 15;70(20):8179-86. doi: 10.1158/0008-5472.CAN-10-1871. Epub 2010 Oct 5.

12.

Endothelial membrane remodeling is obligate for anti-angiogenic radiosensitization during tumor radiosurgery.

Truman JP, García-Barros M, Kaag M, Hambardzumyan D, Stancevic B, Chan M, Fuks Z, Kolesnick R, Haimovitz-Friedman A.

PLoS One. 2010 Aug 19;5(8):e12310. doi: 10.1371/journal.pone.0012310. Corrected and republished in: PLoS One. 2010;5(9). doi: 10.1371/annotation/6e222ad5-b175-4a00-9d04-4d120568a897.

13.

Host acid sphingomyelinase regulates microvascular function not tumor immunity.

Garcia-Barros M, Lacorazza D, Petrie H, Haimovitz-Friedman A, Cardon-Cardo C, Nimer S, Fuks Z, Kolesnick R.

Cancer Res. 2004 Nov 15;64(22):8285-91.

14.

Tumor response to radiotherapy regulated by endothelial cell apoptosis.

Garcia-Barros M, Paris F, Cordon-Cardo C, Lyden D, Rafii S, Haimovitz-Friedman A, Fuks Z, Kolesnick R.

Science. 2003 May 16;300(5622):1155-9.

15.

Proteolytic processing of human growth hormone (GH) by rat tissues in vitro: influence of sex and age.

Garcia-Barros M, Devesa J, Arce VM.

J Endocrinol Invest. 2000 Dec;23(11):748-54.

PMID:
11194709
16.

Role of growth hormone receptor in HL-60 cell survival.

Costoya JA, Ríos R, García-Barros M, Gallego R, García-Caballero T, Señarís R, Arce VM, Devesa J.

Mol Cell Biol Res Commun. 2000 Jul;4(1):26-31.

PMID:
11152624
17.

N-glycosylated variants of growth hormone in human pituitary extracts.

García-Barros M, Costoya JA, Ríos R, Arce V, Devesa J.

Horm Res. 2000;53(1):40-5.

PMID:
10965220
18.

Correlation of Pit-1 gene expression and Pit-1 content with proliferation and differentiation in human myeloid leukemic cells.

Costoya JA, García-Barros M, Gallego R, Señarís R, Arce VM, Devesa J.

Exp Cell Res. 1998 Nov 25;245(1):132-6.

PMID:
9828108
19.

Expression of the human growth hormone normal gene (hGH-N) in proliferating and differentiated HL-60 cells.

Costoya JA, Vidal A, García-Barros M, Arce V, Devesa J.

Exp Cell Res. 1996 Oct 10;228(1):164-7.

PMID:
8892984
20.

Clonidine potentiates the growth hormone response to a growth hormone releasing hormone challenge in hypothalamic growth hormone releasing hormone deficient rats.

Arce V, García Barros M, Vara E, Lima L, Tresguerres JA, Devesa J.

Neuroendocrinology. 1995 May;61(5):552-8.

PMID:
7617133

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