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Items: 28


Revisiting Vascular Remodeling in the Single-Cell Transcriptome Era.

Zhang J, Chang L, Garcia-Barrio MT, Chen YE.

Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):1896-1898. doi: 10.1161/ATVBAHA.119.313174. Epub 2019 Sep 25. No abstract available.


Novel gene regulatory networks identified in response to nitro-conjugated linoleic acid in human endothelial cells.

Lu H, Sun J, Liang W, Zhang J, Rom O, Garcia-Barrio MT, Li S, Villacorta L, Schopfer FJ, Freeman BA, Chen YE, Fan Y.

Physiol Genomics. 2019 Jun 1;51(6):224-233. doi: 10.1152/physiolgenomics.00127.2018. Epub 2019 May 10.


KLF11 (Krüppel-Like Factor 11) Inhibits Arterial Thrombosis via Suppression of Tissue Factor in the Vascular Wall.

Liang W, Fan Y, Lu H, Chang Z, Hu W, Sun J, Wang H, Zhu T, Wang J, Adili R, Garcia-Barrio MT, Holinstat M, Eitzman D, Zhang J, Chen YE.

Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):402-412. doi: 10.1161/ATVBAHA.118.311612.


Krüppel-like factor 14, a coronary artery disease associated transcription factor, inhibits endothelial inflammation via NF-κB signaling pathway.

Hu W, Lu H, Zhang J, Fan Y, Chang Z, Liang W, Wang H, Zhu T, Garcia-Barrio MT, Peng D, Chen YE, Guo Y.

Atherosclerosis. 2018 Nov;278:39-48. doi: 10.1016/j.atherosclerosis.2018.09.018. Epub 2018 Sep 15.


Direct Reprogramming of Fibroblasts Into Smooth Muscle-Like Cells With Defined Transcription Factors-Brief Report.

Hirai H, Yang B, Garcia-Barrio MT, Rom O, Ma PX, Zhang J, Chen YE.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2191-2197. doi: 10.1161/ATVBAHA.118.310870.


Brown Adipocyte-Specific PPARγ (Peroxisome Proliferator-Activated Receptor γ) Deletion Impairs Perivascular Adipose Tissue Development and Enhances Atherosclerosis in Mice.

Xiong W, Zhao X, Villacorta L, Rom O, Garcia-Barrio MT, Guo Y, Fan Y, Zhu T, Zhang J, Zeng R, Chen YE, Jiang Z, Chang L.

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1738-1747. doi: 10.1161/ATVBAHA.118.311367.


Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic Angiogenesis.

Fan Y, Lu H, Liang W, Garcia-Barrio MT, Guo Y, Zhang J, Zhu T, Hao Y, Zhang J, Chen YE.

Circ Res. 2018 Mar 30;122(7):945-957. doi: 10.1161/CIRCRESAHA.118.312672. Epub 2018 Feb 21.


Synthetic High-Density Lipoprotein-Mediated Targeted Delivery of Liver X Receptors Agonist Promotes Atherosclerosis Regression.

Guo Y, Yuan W, Yu B, Kuai R, Hu W, Morin EE, Garcia-Barrio MT, Zhang J, Moon JJ, Schwendeman A, Eugene Chen Y.

EBioMedicine. 2018 Feb;28:225-233. doi: 10.1016/j.ebiom.2017.12.021. Epub 2017 Dec 20.


MitoNEET in Perivascular Adipose Tissue Blunts Atherosclerosis under Mild Cold Condition in Mice.

Xiong W, Zhao X, Garcia-Barrio MT, Zhang J, Lin J, Chen YE, Jiang Z, Chang L.

Front Physiol. 2017 Dec 19;8:1032. doi: 10.3389/fphys.2017.01032. eCollection 2017.


Brown Adipose Tissue, Not Just a Heater.

Chang L, Garcia-Barrio MT, Chen YE.

Arterioscler Thromb Vasc Biol. 2017 Mar;37(3):389-391. doi: 10.1161/ATVBAHA.116.308909. No abstract available.


Experimental Biology for the Identification of Causal Pathways in Atherosclerosis.

Guo Y, Garcia-Barrio MT, Wang L, Chen YE.

Cardiovasc Drugs Ther. 2016 Feb;30(1):1-11. doi: 10.1007/s10557-016-6644-7. Review.


Hepatic Transmembrane 6 Superfamily Member 2 Regulates Cholesterol Metabolism in Mice.

Fan Y, Lu H, Guo Y, Zhu T, Garcia-Barrio MT, Jiang Z, Willer CJ, Zhang J, Chen YE.

Gastroenterology. 2016 May;150(5):1208-1218. doi: 10.1053/j.gastro.2016.01.005. Epub 2016 Jan 13.


Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.

Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE.

J Clin Invest. 2015 Oct 1;125(10):3819-30. doi: 10.1172/JCI79048. Epub 2015 Sep 14.


Rad GTPase induces cardiomyocyte apoptosis through the activation of p38 mitogen-activated protein kinase.

Sun Z, Zhang J, Zhang J, Chen C, Du Q, Chang L, Cao C, Zheng M, Garcia-Barrio MT, Chen YE, Xiao RP, Mao J, Zhu X.

Biochem Biophys Res Commun. 2011 May 27;409(1):52-7. doi: 10.1016/j.bbrc.2011.04.104. Epub 2011 Apr 28.


MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4.

Xie C, Huang H, Sun X, Guo Y, Hamblin M, Ritchie RP, Garcia-Barrio MT, Zhang J, Chen YE.

Stem Cells Dev. 2011 Feb;20(2):205-10. doi: 10.1089/scd.2010.0283. Epub 2010 Oct 18.


Nitro-oleic acid inhibits angiotensin II-induced hypertension.

Zhang J, Villacorta L, Chang L, Fan Z, Hamblin M, Zhu T, Chen CS, Cole MP, Schopfer FJ, Deng CX, Garcia-Barrio MT, Feng YH, Freeman BA, Chen YE.

Circ Res. 2010 Aug 20;107(4):540-8. doi: 10.1161/CIRCRESAHA.110.218404. Epub 2010 Jun 17.


Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions.

Schopfer FJ, Cole MP, Groeger AL, Chen CS, Khoo NK, Woodcock SR, Golin-Bisello F, Motanya UN, Li Y, Zhang J, Garcia-Barrio MT, Rudolph TK, Rudolph V, Bonacci G, Baker PR, Xu HE, Batthyany CI, Chen YE, Hallis TM, Freeman BA.

J Biol Chem. 2010 Apr 16;285(16):12321-33. doi: 10.1074/jbc.M109.091512. Epub 2010 Jan 22.


Vascular smooth muscle cell-selective peroxisome proliferator-activated receptor-gamma deletion leads to hypotension.

Chang L, Villacorta L, Zhang J, Garcia-Barrio MT, Yang K, Hamblin M, Whitesall SE, D'Alecy LG, Chen YE.

Circulation. 2009 Apr 28;119(16):2161-9. doi: 10.1161/CIRCULATIONAHA.108.815803. Epub 2009 Apr 13.


Expression profiling of nuclear receptors in human and mouse embryonic stem cells.

Xie CQ, Jeong Y, Fu M, Bookout AL, Garcia-Barrio MT, Sun T, Kim BH, Xie Y, Root S, Zhang J, Xu RH, Chen YE, Mangelsdorf DJ.

Mol Endocrinol. 2009 May;23(5):724-33. doi: 10.1210/me.2008-0465. Epub 2009 Feb 5.


Molecular recognition of nitrated fatty acids by PPAR gamma.

Li Y, Zhang J, Schopfer FJ, Martynowski D, Garcia-Barrio MT, Kovach A, Suino-Powell K, Baker PR, Freeman BA, Chen YE, Xu HE.

Nat Struct Mol Biol. 2008 Aug;15(8):865-7. doi: 10.1038/nsmb.1447. Epub 2008 Jul 6.


Transcriptional regulation of peroxisome proliferator-activated receptors and liver X receptors.

Villacorta L, Garcia-Barrio MT, Chen YE.

Curr Atheroscler Rep. 2007 Sep;9(3):230-7. Review.


Interleukin-1 beta-induced Id2 gene expression is mediated by Egr-1 in vascular smooth muscle cells.

Zhu X, Lin Y, Bacanamwo M, Chang L, Chai R, Massud I, Zhang J, Garcia-Barrio MT, Thompson WE, Chen YE.

Cardiovasc Res. 2007 Oct 1;76(1):141-8. Epub 2007 Jun 22.


Nitro-linoleic acid inhibits vascular smooth muscle cell proliferation via the Keap1/Nrf2 signaling pathway.

Villacorta L, Zhang J, Garcia-Barrio MT, Chen XL, Freeman BA, Chen YE, Cui T.

Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H770-6. Epub 2007 Apr 27.


GCD14p, a repressor of GCN4 translation, cooperates with Gcd10p and Lhp1p in the maturation of initiator methionyl-tRNA in Saccharomyces cerevisiae.

Calvo O, Cuesta R, Anderson J, Gutiérrez N, García-Barrio MT, Hinnebusch AG, Tamame M.

Mol Cell Biol. 1999 Jun;19(6):4167-81.


Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain.

Romano PR, Zhang F, Tan SL, Garcia-Barrio MT, Katze MG, Dever TE, Hinnebusch AG.

Mol Cell Biol. 1998 Dec;18(12):7304-16.


Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2.

Romano PR, Garcia-Barrio MT, Zhang X, Wang Q, Taylor DR, Zhang F, Herring C, Mathews MB, Qin J, Hinnebusch AG.

Mol Cell Biol. 1998 Apr;18(4):2282-97.


GCD10, a translational repressor of GCN4, is the RNA-binding subunit of eukaryotic translation initiation factor-3.

Garcia-Barrio MT, Naranda T, Vazquez de Aldana CR, Cuesta R, Hinnebusch AG, Hershey JW, Tamame M.

Genes Dev. 1995 Jul 15;9(14):1781-96.

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