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Items: 44

1.

The financial and time burden associated with phenylketonuria treatment in the United States.

Rose AM, Grosse SD, Garcia SP, Bach J, Kleyn M, Simon NE, Prosser LA.

Mol Genet Metab Rep. 2019 Oct 16;21:100523. doi: 10.1016/j.ymgmr.2019.100523. eCollection 2019 Dec.

2.

High levels of AAV vector integration into CRISPR-induced DNA breaks.

Hanlon KS, Kleinstiver BP, Garcia SP, Zaborowski MP, Volak A, Spirig SE, Muller A, Sousa AA, Tsai SQ, Bengtsson NE, Lööv C, Ingelsson M, Chamberlain JS, Corey DP, Aryee MJ, Joung JK, Breakefield XO, Maguire CA, György B.

Nat Commun. 2019 Sep 30;10(1):4439. doi: 10.1038/s41467-019-12449-2.

3.

CRISPR DNA base editors with reduced RNA off-target and self-editing activities.

Grünewald J, Zhou R, Iyer S, Lareau CA, Garcia SP, Aryee MJ, Joung JK.

Nat Biotechnol. 2019 Sep;37(9):1041-1048. doi: 10.1038/s41587-019-0236-6. Epub 2019 Sep 2.

PMID:
31477922
4.

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss.

György B, Nist-Lund C, Pan B, Asai Y, Karavitaki KD, Kleinstiver BP, Garcia SP, Zaborowski MP, Solanes P, Spataro S, Schneider BL, Joung JK, Géléoc GSG, Holt JR, Corey DP.

Nat Med. 2019 Jul;25(7):1123-1130. doi: 10.1038/s41591-019-0500-9. Epub 2019 Jul 3.

PMID:
31270503
5.

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors.

Grünewald J, Zhou R, Garcia SP, Iyer S, Lareau CA, Aryee MJ, Joung JK.

Nature. 2019 May;569(7756):433-437. doi: 10.1038/s41586-019-1161-z. Epub 2019 Apr 17.

6.

A dynamic and integrated epigenetic program at distal regions orchestrates transcriptional responses to VEGFA.

Wang S, Chen J, Garcia SP, Liang X, Zhang F, Yan P, Yu H, Wei W, Li Z, Wang J, Le H, Han Z, Luo X, Day DS, Stevens SM, Zhang Y, Park PJ, Liu ZJ, Sun K, Yuan GC, Pu WT, Zhang B.

Genome Res. 2019 Feb;29(2):193-207. doi: 10.1101/gr.239053.118. Epub 2019 Jan 22.

7.

Molecularly distinct models of zebrafish Myc-induced B cell leukemia.

Borga C, Foster CA, Iyer S, Garcia SP, Langenau DM, Frazer JK.

Leukemia. 2019 Feb;33(2):559-562. doi: 10.1038/s41375-018-0328-1. Epub 2018 Dec 20. No abstract available.

8.

Antipsychotics and cardiovascular risk: A case/non-case study.

Arias LHM, Fadrique RS, García SP, Gil MS, Lobato CT, Ortega PG.

Psychiatry Res. 2018 Dec;270:341-347. doi: 10.1016/j.psychres.2018.09.014. Epub 2018 Sep 18.

PMID:
30292087
9.

In vivo CRISPR editing with no detectable genome-wide off-target mutations.

Akcakaya P, Bobbin ML, Guo JA, Malagon-Lopez J, Clement K, Garcia SP, Fellows MD, Porritt MJ, Firth MA, Carreras A, Baccega T, Seeliger F, Bjursell M, Tsai SQ, Nguyen NT, Nitsch R, Mayr LM, Pinello L, Bohlooly-Y M, Aryee MJ, Maresca M, Joung JK.

Nature. 2018 Sep;561(7723):416-419. doi: 10.1038/s41586-018-0500-9. Epub 2018 Sep 12.

10.

tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish.

Ignatius MS, Hayes MN, Moore FE, Tang Q, Garcia SP, Blackburn PR, Baxi K, Wang L, Jin A, Ramakrishnan A, Reeder S, Chen Y, Nielsen GP, Chen EY, Hasserjian RP, Tirode F, Ekker SC, Langenau DM.

Elife. 2018 Sep 7;7. pii: e37202. doi: 10.7554/eLife.37202.

11.

Incremental Health Care Costs Associated With Food Insecurity and Chronic Conditions Among Older Adults.

Garcia SP, Haddix A, Barnett K.

Prev Chronic Dis. 2018 Aug 30;15:E108. doi: 10.5888/pcd15.180058.

12.

Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia.

Garcia EG, Iyer S, Garcia SP, Loontiens S, Sadreyev RI, Speleman F, Langenau DM.

Leukemia. 2018 Aug;32(8):1860-1865. doi: 10.1038/s41375-018-0130-0. Epub 2018 Apr 18. No abstract available.

13.

Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma.

Hayes MN, McCarthy K, Jin A, Oliveira ML, Iyer S, Garcia SP, Sindiri S, Gryder B, Motala Z, Nielsen GP, Borg JP, van de Rijn M, Malkin D, Khan J, Ignatius MS, Langenau DM.

Cell Stem Cell. 2018 Mar 1;22(3):414-427.e6. doi: 10.1016/j.stem.2018.02.002.

14.

Clinical-Community Partnerships to Identify Patients With Food Insecurity and Address Food Needs.

Lundeen EA, Siegel KR, Calhoun H, Kim SA, Garcia SP, Hoeting NM, Harris DM, Khan LK, Smith B, Blanck HM, Barnett K, Haddix AC.

Prev Chronic Dis. 2017 Nov 16;14:E113. doi: 10.5888/pcd14.170343.

15.

An algorithm to locate optimal bond breaking points on a potential energy surface for applications in mechanochemistry and catalysis.

Bofill JM, Ribas-Ariño J, García SP, Quapp W.

J Chem Phys. 2017 Oct 21;147(15):152710. doi: 10.1063/1.4994925.

16.

Factor H Competitor Generated by Gene Conversion Events Associates with Atypical Hemolytic Uremic Syndrome.

Goicoechea de Jorge E, Tortajada A, García SP, Gastoldi S, Merinero HM, García-Fernández J, Arjona E, Cao M, Remuzzi G, Noris M, Rodríguez de Córdoba S.

J Am Soc Nephrol. 2018 Jan;29(1):240-249. doi: 10.1681/ASN.2017050518. Epub 2017 Oct 9.

17.

Complete functional characterization of disease-associated genetic variants in the complement factor H gene.

Merinero HM, García SP, García-Fernández J, Arjona E, Tortajada A, Rodríguez de Córdoba S.

Kidney Int. 2018 Feb;93(2):470-481. doi: 10.1016/j.kint.2017.07.015. Epub 2017 Sep 21.

PMID:
28941939
18.

Potency of Human Cardiosphere-Derived Cells from Patients with Ischemic Heart Disease Is Associated with Robust Vascular Supportive Ability.

Harvey E, Zhang H, Sepúlveda P, Garcia SP, Sweeney D, Choudry FA, Castellano D, Thomas GN, Kattach H, Petersen R, Blake DJ, Taggart DP, Frontini M, Watt SM, Martin-Rendon E.

Stem Cells Transl Med. 2017 May;6(5):1399-1411. doi: 10.1002/sctm.16-0229. Epub 2017 Feb 16.

19.

Extravascular hemolysis and complement consumption in Paroxysmal Nocturnal Hemoglobinuria patients undergoing eculizumab treatment.

Subías Hidalgo M, Martin Merinero H, López A, Anter J, García SP, Ataúlfo Gonzalez-Fernández F, Forés R, Lopez-Trascasa M, Villegas A, Ojeda E, Rodríguez de Córdoba S.

Immunobiology. 2017 Feb;222(2):363-371. doi: 10.1016/j.imbio.2016.09.002. Epub 2016 Sep 13.

20.

Robust lineage reconstruction from high-dimensional single-cell data.

Giecold G, Marco E, Garcia SP, Trippa L, Yuan GC.

Nucleic Acids Res. 2016 Aug 19;44(14):e122. doi: 10.1093/nar/gkw452. Epub 2016 May 20.

21.

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.

Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, Yuan GC, Zhang F, Orkin SH, Bauer DE.

Nature. 2015 Nov 12;527(7577):192-7. doi: 10.1038/nature15521. Epub 2015 Sep 16.

22.

Transcriptional diversity during lineage commitment of human blood progenitors.

Chen L, Kostadima M, Martens JHA, Canu G, Garcia SP, Turro E, Downes K, Macaulay IC, Bielczyk-Maczynska E, Coe S, Farrow S, Poudel P, Burden F, Jansen SBG, Astle WJ, Attwood A, Bariana T, de Bono B, Breschi A, Chambers JC, Consortium B, Choudry FA, Clarke L, Coupland P, van der Ent M, Erber WN, Jansen JH, Favier R, Fenech ME, Foad N, Freson K, van Geet C, Gomez K, Guigo R, Hampshire D, Kelly AM, Kerstens HHD, Kooner JS, Laffan M, Lentaigne C, Labalette C, Martin T, Meacham S, Mumford A, Nürnberg S, Palumbo E, van der Reijden BA, Richardson D, Sammut SJ, Slodkowicz G, Tamuri AU, Vasquez L, Voss K, Watt S, Westbury S, Flicek P, Loos R, Goldman N, Bertone P, Read RJ, Richardson S, Cvejic A, Soranzo N, Ouwehand WH, Stunnenberg HG, Frontini M, Rendon A.

Science. 2014 Sep 26;345(6204):1251033. doi: 10.1126/science.1251033.

23.

Major components of metabolic syndrome and adiponectin levels: a cross-sectional study.

von Frankenberg AD, do Nascimento FV, Gatelli LE, Nedel BL, Garcia SP, de Oliveira CS, Saddi-Rosa P, Reis AF, Canani LH, Gerchman F.

Diabetol Metab Syndr. 2014 Feb 26;6(1):26. doi: 10.1186/1758-5996-6-26.

24.

DNA sequences at a glance.

Pinho AJ, Garcia SP, Pratas D, Ferreira PJ.

PLoS One. 2013 Nov 21;8(11):e79922. doi: 10.1371/journal.pone.0079922. eCollection 2013.

25.

Inter-STOP symbol distances for the identification of coding regions.

Bastos CA, Afreixo V, Garcia SP, Pinho AJ.

J Integr Bioinform. 2013 Nov 14;10(3):230. doi: 10.2390/biecoll-jib-2013-230.

PMID:
24231144
26.

Compressing resequencing data with GReEn.

Pinho AJ, Pratas D, Garcia SP.

Methods Mol Biol. 2013;1038:27-37. doi: 10.1007/978-1-62703-514-9_2.

PMID:
23872967
27.

The breakdown of the word symmetry in the human genome.

Afreixo V, Bastos CA, Garcia SP, Rodrigues JM, Pinho AJ, Ferreira PJ.

J Theor Biol. 2013 Oct 21;335:153-9. doi: 10.1016/j.jtbi.2013.06.032. Epub 2013 Jul 2.

PMID:
23831271
28.

A genomic distance for assembly comparison based on compressed maximal exact matches.

Garcia SP, Rodrigues JM, Santos S, Pratas D, Afreixo V, Bastos CA, Ferreira PJ, Pinho AJ.

IEEE/ACM Trans Comput Biol Bioinform. 2013 May-Jun;10(3):793-8.

PMID:
25594089
29.

Prevalence of anxiety and depression among outpatients with type 2 diabetes in the Mexican population.

Tovilla-Zárate C, Juárez-Rojop I, Peralta Jimenez Y, Jiménez MA, Vázquez S, Bermúdez-Ocaña D, Ramón-Frías T, Genis Mendoza AD, García SP, Narváez LL.

PLoS One. 2012;7(5):e36887. doi: 10.1371/journal.pone.0036887. Epub 2012 May 18.

30.

Minimal absent words in four human genome assemblies.

Garcia SP, Pinho AJ.

PLoS One. 2011;6(12):e29344. doi: 10.1371/journal.pone.0029344. Epub 2011 Dec 29.

31.

GReEn: a tool for efficient compression of genome resequencing data.

Pinho AJ, Pratas D, Garcia SP.

Nucleic Acids Res. 2012 Feb;40(4):e27. doi: 10.1093/nar/gkr1124. Epub 2011 Dec 1.

32.

Inter-dinucleotide distances in the human genome: an analysis of the whole-genome and protein-coding distributions.

Bastos CA, Afreixo V, Pinho AJ, Garcia SP, Rodrigues JM, Ferreira PJ.

J Integr Bioinform. 2011 Sep 15;8(3):172. doi: 10.2390/biecoll-jib-2011-172.

PMID:
21926435
33.

Minimal absent words in prokaryotic and eukaryotic genomes.

Garcia SP, Pinho AJ, Rodrigues JM, Bastos CA, Ferreira PJ.

PLoS One. 2011 Jan 31;6(1):e16065. doi: 10.1371/journal.pone.0016065.

34.

Genome analysis with distance to the nearest dissimilar nucleotide.

Afreixo V, Bastos CA, Pinho AJ, Garcia SP, Ferreira PJ.

J Theor Biol. 2011 Apr 21;275(1):52-8. doi: 10.1016/j.jtbi.2011.01.038. Epub 2011 Feb 2.

PMID:
21295040
35.

Genome analysis with inter-nucleotide distances.

Afreixo V, Bastos CA, Pinho AJ, Garcia SP, Ferreira PJ.

Bioinformatics. 2009 Dec 1;25(23):3064-70. doi: 10.1093/bioinformatics/btp546. Epub 2009 Sep 16.

36.

Synthesis and optical properties of aqueous soluble indolylfulgimides.

Chen X, Islamova NI, Garcia SP, DiGirolamo JA, Lees WJ.

J Org Chem. 2009 Sep 4;74(17):6777-83. doi: 10.1021/jo900909d.

37.

On finding minimal absent words.

Pinho AJ, Ferreira PJ, Garcia SP, Rodrigues JM.

BMC Bioinformatics. 2009 May 8;10:137. doi: 10.1186/1471-2105-10-137.

38.

Response to methylphenidate in children and adolescents with ADHD: does comorbid anxiety disorders matters?

Garcia SP, Guimarães J, Zampieri JF, Martinez AL, Polanczyk G, Rohde LA.

J Neural Transm (Vienna). 2009 May;116(5):631-6. doi: 10.1007/s00702-009-0211-3. Epub 2009 Apr 16.

PMID:
19370390
39.

Multivariate phase space reconstruction by nearest neighbor embedding with different time delays.

Garcia SP, Almeida JS.

Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Aug;72(2 Pt 2):027205. Epub 2005 Aug 31.

PMID:
16196759
40.

Nearest neighbor embedding with different time delays.

Garcia SP, Almeida JS.

Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Mar;71(3 Pt 2B):037204. Epub 2005 Mar 29.

PMID:
15903641
41.

Etchant anisotropy controls the step bunching instability in KOH etching of silicon.

Garcia SP, Bao H, Hines MA.

Phys Rev Lett. 2004 Oct 15;93(16):166102. Epub 2004 Oct 14.

PMID:
15525007
42.

A prospective duplex Doppler ultrasonographic study in women with sexual arousal disorder to objectively assess genital engorgement induced by EROS therapy.

Munarriz R, Maitland S, Garcia SP, Talakoub L, Goldstein I.

J Sex Marital Ther. 2003;29 Suppl 1:85-94.

PMID:
12735092
44.

An odyssey through Iliad.

Rootenberg JD, Garcia SP.

JAMA. 1990 Feb 2;263(5):758-9. No abstract available.

PMID:
2296133

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