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Items: 1 to 50 of 300

1.

Capturing the Onset of PRC2-Mediated Repressive Domain Formation.

Oksuz O, Narendra V, Lee CH, Descostes N, LeRoy G, Raviram R, Blumenberg L, Karch K, Rocha PP, Garcia BA, Skok JA, Reinberg D.

Mol Cell. 2018 Jun 21;70(6):1149-1162.e5. doi: 10.1016/j.molcel.2018.05.023.

PMID:
29932905
2.

Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism.

Zhang X, Xue C, Lin J, Ferguson JF, Weiner A, Liu W, Han Y, Hinkle C, Li W, Jiang H, Gosai S, Hachet M, Garcia BA, Gregory BD, Soccio RE, Hogenesch JB, Seale P, Li M, Reilly MP.

Sci Transl Med. 2018 Jun 20;10(446). pii: eaar5987. doi: 10.1126/scitranslmed.aar5987.

PMID:
29925637
3.

Rpp29 regulates histone H3.3 chromatin assembly through transcriptional mechanisms.

Shastrula PK, Lund PJ, Garcia BA, Janicki SM.

J Biol Chem. 2018 Jun 19. pii: jbc.RA118.001845. doi: 10.1074/jbc.RA118.001845. [Epub ahead of print]

4.

High-Quality Genome Assemblies Reveal Long Non-coding RNAs Expressed in Ant Brains.

Shields EJ, Sheng L, Weiner AK, Garcia BA, Bonasio R.

Cell Rep. 2018 Jun 5;23(10):3078-3090. doi: 10.1016/j.celrep.2018.05.014.

5.

An allosteric propofol-binding site in kinesin disrupts kinesin-mediated processive movement on microtubules.

Woll KA, Guzik-Lendrum S, Bensel BM, Bhanu NV, Dailey WP, Garcia BA, Gilbert SP, Eckenhoff RG.

J Biol Chem. 2018 May 29. pii: jbc.RA118.002182. doi: 10.1074/jbc.RA118.002182. [Epub ahead of print]

6.

EpiProfile 2.0: A Computational Platform for Processing Epi-Proteomics Mass Spectrometry Data.

Yuan ZF, Sidoli S, Marchione DM, Simithy J, Janssen KA, Szurgot MR, Garcia BA.

J Proteome Res. 2018 May 30. doi: 10.1021/acs.jproteome.8b00133. [Epub ahead of print]

PMID:
29790754
7.

Applicability of Precision Medicine Approaches to Managing Hypertension in Rural Populations.

Halladay JR, Lenhart KC, Robasky K, Jones W, Homan WF, Cummings DM, Cené CW, Hinderliter AL, Miller CL, Donahue KE, Garcia BA, Keyserling TC, Ammerman AS, Patterson C, DeWalt DA, Johnston LF, Willis MS, Schisler JC.

J Pers Med. 2018 Apr 30;8(2). pii: E16. doi: 10.3390/jpm8020016.

8.

Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin.

Lee CH, Yu JR, Kumar S, Jin Y, LeRoy G, Bhanu N, Kaneko S, Garcia BA, Hamilton AD, Reinberg D.

Mol Cell. 2018 May 3;70(3):422-434.e6. doi: 10.1016/j.molcel.2018.03.020. Epub 2018 Apr 19.

PMID:
29681499
9.

Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior.

Sadeghi RS, Kulej K, Kathayat RS, Garcia BA, Dickinson BC, Brady DC, Witze ES.

Elife. 2018 Apr 12;7. pii: e34362. doi: 10.7554/eLife.34362.

10.

Microbes vs. chemistry in the origin of the anaerobic gut lumen.

Friedman ES, Bittinger K, Esipova TV, Hou L, Chau L, Jiang J, Mesaros C, Lund PJ, Liang X, FitzGerald GA, Goulian M, Lee D, Garcia BA, Blair IA, Vinogradov SA, Wu GD.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4170-4175. doi: 10.1073/pnas.1718635115. Epub 2018 Apr 2.

PMID:
29610310
11.

Integrating Proteomics and Targeted Metabolomics to Understand Global Changes in Histone Modifications.

Simithy J, Sidoli S, Garcia BA.

Proteomics. 2018 Mar 7:e1700309. doi: 10.1002/pmic.201700309. [Epub ahead of print] Review.

PMID:
29512899
12.

Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors.

Woll KA, Zhou X, Bhanu NV, Garcia BA, Covarrubias M, Miller KW, Eckenhoff RG.

FASEB J. 2018 Mar 5:fj201701347R. doi: 10.1096/fj.201701347R. [Epub ahead of print]

PMID:
29505303
13.

Implementation of a successful eradication protocol for Burkholderia Cepacia complex in cystic fibrosis patients.

Garcia BA, Carden JL, Goodwin DL, Smith TA, Gaggar A, Leon K, Antony VB, Rowe SM, Solomon GM.

BMC Pulm Med. 2018 Feb 14;18(1):35. doi: 10.1186/s12890-018-0594-8.

14.

How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B.

Nat Chem Biol. 2018 Feb 14;14(3):206-214. doi: 10.1038/nchembio.2576.

PMID:
29443976
15.

KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis.

Lin-Shiao E, Lan Y, Coradin M, Anderson A, Donahue G, Simpson CL, Sen P, Saffie R, Busino L, Garcia BA, Berger SL, Capell BC.

Genes Dev. 2018 Jan 15;32(2):181-193. doi: 10.1101/gad.306241.117. Epub 2018 Feb 12.

PMID:
29440247
16.

cDNA Isolation and Expression of Nicotinamide Adenine Dinucleotide Phosphate-Dependent Cytochrome P450 Reductase Gene in the Chagas Disease Vector Triatoma infestans.

Grosso CG, Stroppa MM, Varela GM, García BA.

Am J Trop Med Hyg. 2018 Mar;98(3):710-716. doi: 10.4269/ajtmh.17-0404. Epub 2018 Jan 18.

PMID:
29363459
17.

Genomic and Proteomic Resolution of Heterochromatin and Its Restriction of Alternate Fate Genes.

Becker JS, McCarthy RL, Sidoli S, Donahue G, Kaeding KE, He Z, Lin S, Garcia BA, Zaret KS.

Mol Cell. 2017 Dec 21;68(6):1023-1037.e15. doi: 10.1016/j.molcel.2017.11.030.

18.

Clock Gene Period in the Chagas Disease Vector Triatoma infestans (Hemiptera: Reduviidae).

Stroppa MM, Gimenez I, García BA.

Am J Trop Med Hyg. 2018 Feb;98(2):468-474. doi: 10.4269/ajtmh.17-0147. Epub 2017 Dec 14.

PMID:
29260645
19.

TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling.

Berson A, Sartoris A, Nativio R, Van Deerlin V, Toledo JB, Porta S, Liu S, Chung CY, Garcia BA, Lee VM, Trojanowski JQ, Johnson FB, Berger SL, Bonini NM.

Curr Biol. 2017 Dec 4;27(23):3579-3590.e6. doi: 10.1016/j.cub.2017.10.024. Epub 2017 Nov 16.

PMID:
29153328
20.

Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia.

Di Marcantonio D, Martinez E, Sidoli S, Vadaketh J, Nieborowska-Skorska M, Gupta A, Meadows JM, Ferraro F, Masselli E, Challen GA, Milsom MD, Scholl C, Fröhling S, Balachandran S, Skorski T, Garcia BA, Mirandola P, Gobbi G, Garzon R, Vitale M, Sykes SM.

Clin Cancer Res. 2018 Feb 1;24(3):608-618. doi: 10.1158/1078-0432.CCR-17-2684. Epub 2017 Nov 10.

PMID:
29127121
21.

Assessment of Quantification Precision of Histone Post-Translational Modifications by Using an Ion Trap and down To 50 000 Cells as Starting Material.

Guo Q, Sidoli S, Garcia BA, Zhao X.

J Proteome Res. 2018 Jan 5;17(1):234-242. doi: 10.1021/acs.jproteome.7b00544. Epub 2017 Nov 21.

PMID:
29121770
22.

Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming.

Tan L, Ke Z, Tombline G, Macoretta N, Hayes K, Tian X, Lv R, Ablaeva J, Gilbert M, Bhanu NV, Yuan ZF, Garcia BA, Shi YG, Shi Y, Seluanov A, Gorbunova V.

Stem Cell Reports. 2017 Nov 14;9(5):1721-1734. doi: 10.1016/j.stemcr.2017.10.001. Epub 2017 Oct 26.

23.

Characterization of histone acylations links chromatin modifications with metabolism.

Simithy J, Sidoli S, Yuan ZF, Coradin M, Bhanu NV, Marchione DM, Klein BJ, Bazilevsky GA, McCullough CE, Magin RS, Kutateladze TG, Snyder NW, Marmorstein R, Garcia BA.

Nat Commun. 2017 Oct 26;8(1):1141. doi: 10.1038/s41467-017-01384-9.

24.

The nucleosomal surface is the main target of histone ADP-ribosylation in response to DNA damage.

Karch KR, Langelier MF, Pascal JM, Garcia BA.

Mol Biosyst. 2017 Nov 21;13(12):2660-2671. doi: 10.1039/c7mb00498b.

PMID:
29058739
25.

Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions.

Warneford-Thomson R, He C, Sidoli S, Garcia BA, Bonasio R.

J Vis Exp. 2017 Sep 28;(127). doi: 10.3791/56004.

PMID:
28994809
26.

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL.

Nature. 2017 Oct 19;550(7676):402-406. doi: 10.1038/nature24050. Epub 2017 Oct 4.

27.

Identifying Host Factors Associated with DNA Replicated During Virus Infection.

Reyes ED, Kulej K, Pancholi NJ, Akhtar LN, Avgousti DC, Kim ET, Bricker DK, Spruce LA, Koniski SA, Seeholzer SH, Isaacs SN, Garcia BA, Weitzman MD.

Mol Cell Proteomics. 2017 Dec;16(12):2079-2097. doi: 10.1074/mcp.M117.067116. Epub 2017 Oct 2.

PMID:
28972080
28.

Eating Well While Dining Out: Collaborating with Local Restaurants to Promote Heart Healthy Menu Items.

Thayer LM, Pimentel DC, Smith JC, Garcia BA, Lee Sylvester L, Kelly T, Johnston LF, Ammerman AS, Keyserling TC.

Am J Health Educ. 2017;48(1):11-21. doi: 10.1080/19325037.2016.1250688. Epub 2016 Dec 29.

29.

Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling.

Woll KA, Skinner KA, Gianti E, Bhanu NV, Garcia BA, Carnevale V, Eckenhoff RG, Gaudet R.

Biophys J. 2017 Nov 21;113(10):2168-2172. doi: 10.1016/j.bpj.2017.08.040. Epub 2017 Sep 19.

PMID:
28935134
30.

An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides.

Armour SM, Remsberg JR, Damle M, Sidoli S, Ho WY, Li Z, Garcia BA, Lazar MA.

Nat Commun. 2017 Sep 15;8(1):549. doi: 10.1038/s41467-017-00772-5.

31.

Phosphoproteomics reveals that glycogen synthase kinase-3 phosphorylates multiple splicing factors and is associated with alternative splicing.

Shinde MY, Sidoli S, Kulej K, Mallory MJ, Radens CM, Reicherter AL, Myers RL, Barash Y, Lynch KW, Garcia BA, Klein PS.

J Biol Chem. 2017 Nov 3;292(44):18240-18255. doi: 10.1074/jbc.M117.813527. Epub 2017 Sep 15.

32.

Proteome-wide acetylation dynamics in human cells.

Kori Y, Sidoli S, Yuan ZF, Lund PJ, Zhao X, Garcia BA.

Sci Rep. 2017 Aug 31;7(1):10296. doi: 10.1038/s41598-017-09918-3.

33.

Identification of Nidogen 1 as a lung metastasis protein through secretome analysis.

Alečković M, Wei Y, LeRoy G, Sidoli S, Liu DD, Garcia BA, Kang Y.

Genes Dev. 2017 Jul 15;31(14):1439-1455. doi: 10.1101/gad.301937.117. Epub 2017 Aug 21.

34.

The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants.

Gospocic J, Shields EJ, Glastad KM, Lin Y, Penick CA, Yan H, Mikheyev AS, Linksvayer TA, Garcia BA, Berger SL, Liebig J, Reinberg D, Bonasio R.

Cell. 2017 Aug 10;170(4):748-759.e12. doi: 10.1016/j.cell.2017.07.014.

PMID:
28802044
35.

Silencing of Two Vitellogenin Genes Inhibits Oviposition in the Chagas Disease Vector Triatoma infestans (Hemiptera: Reduviidae).

Blariza MJ, Grosso CG, García BA.

Am J Trop Med Hyg. 2017 Aug;97(2):477-480. doi: 10.4269/ajtmh.16-1029. Epub 2017 Jul 19.

PMID:
28722589
36.

Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem cells via Kdm3a/b.

Ebata KT, Mesh K, Liu S, Bilenky M, Fekete A, Acker MG, Hirst M, Garcia BA, Ramalho-Santos M.

Epigenetics Chromatin. 2017 Jul 12;10:36. doi: 10.1186/s13072-017-0143-3. eCollection 2017.

37.

Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers.

Kim J, Bamlet WR, Oberg AL, Chaffee KG, Donahue G, Cao XJ, Chari S, Garcia BA, Petersen GM, Zaret KS.

Sci Transl Med. 2017 Jul 12;9(398). pii: eaah5583. doi: 10.1126/scitranslmed.aah5583.

38.

Metabolic labeling in middle-down proteomics allows for investigation of the dynamics of the histone code.

Sidoli S, Lu C, Coradin M, Wang X, Karch KR, Ruminowicz C, Garcia BA.

Epigenetics Chromatin. 2017 Jul 6;10(1):34. doi: 10.1186/s13072-017-0139-z.

39.

Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription.

Jih G, Iglesias N, Currie MA, Bhanu NV, Paulo JA, Gygi SP, Garcia BA, Moazed D.

Nature. 2017 Jul 27;547(7664):463-467. doi: 10.1038/nature23267. Epub 2017 Jun 22.

40.

Middle-down proteomics: a still unexploited resource for chromatin biology.

Sidoli S, Garcia BA.

Expert Rev Proteomics. 2017 Jul;14(7):617-626. doi: 10.1080/14789450.2017.1345632. Epub 2017 Jun 28. Review.

PMID:
28649883
41.

Uncovering BRD4 hyperphosphorylation associated with cellular transformation in NUT midline carcinoma.

Wang R, Cao XJ, Kulej K, Liu W, Ma T, MacDonald M, Chiang CM, Garcia BA, You J.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):E5352-E5361. doi: 10.1073/pnas.1703071114. Epub 2017 Jun 19.

42.

The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis.

Herriges MJ, Tischfield DJ, Cui Z, Morley MP, Han Y, Babu A, Li S, Lu M, Cendan I, Garcia BA, Anderson SA, Morrisey EE.

Genes Dev. 2017 May 1;31(9):889-903. doi: 10.1101/gad.298018.117. Epub 2017 May 25.

43.

Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.

Dalvi MP, Wang L, Zhong R, Kollipara RK, Park H, Bayo J, Yenerall P, Zhou Y, Timmons BC, Rodriguez-Canales J, Behrens C, Mino B, Villalobos P, Parra ER, Suraokar M, Pataer A, Swisher SG, Kalhor N, Bhanu NV, Garcia BA, Heymach JV, Coombes K, Xie Y, Girard L, Gazdar AF, Kittler R, Wistuba II, Minna JD, Martinez ED.

Cell Rep. 2017 May 23;19(8):1669-1684. doi: 10.1016/j.celrep.2017.04.077.

44.

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

Dorighi KM, Swigut T, Henriques T, Bhanu NV, Scruggs BS, Nady N, Still CD 2nd, Garcia BA, Adelman K, Wysocka J.

Mol Cell. 2017 May 18;66(4):568-576.e4. doi: 10.1016/j.molcel.2017.04.018. Epub 2017 May 5.

45.

Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression.

Fiziev P, Akdemir KC, Miller JP, Keung EZ, Samant NS, Sharma S, Natale CA, Terranova CJ, Maitituoheti M, Amin SB, Martinez-Ledesma E, Dhamdhere M, Axelrad JB, Shah A, Cheng CS, Mahadeshwar H, Seth S, Barton MC, Protopopov A, Tsai KY, Davies MA, Garcia BA, Amit I, Chin L, Ernst J, Rai K.

Cell Rep. 2017 Apr 25;19(4):875-889. doi: 10.1016/j.celrep.2017.03.078.

46.

A Global View of RNA-Protein Interactions Identifies Post-transcriptional Regulators of Root Hair Cell Fate.

Foley SW, Gosai SJ, Wang D, Selamoglu N, Sollitti AC, Köster T, Steffen A, Lyons E, Daldal F, Garcia BA, Staiger D, Deal RB, Gregory BD.

Dev Cell. 2017 Apr 24;41(2):204-220.e5. doi: 10.1016/j.devcel.2017.03.018.

47.

Successful long-term weight loss among participants with diabetes receiving an intervention promoting an adapted Mediterranean-style dietary pattern: the Heart Healthy Lenoir Project.

Embree GG, Samuel-Hodge CD, Johnston LF, Garcia BA, Gizlice Z, Evenson KR, DeWalt DA, Ammerman AS, Keyserling TC.

BMJ Open Diabetes Res Care. 2017 Mar 29;5(1):e000339. doi: 10.1136/bmjdrc-2016-000339. eCollection 2017.

48.

Monitoring proteolytic processing events by quantitative mass spectrometry.

Coradin M, Karch KR, Garcia BA.

Expert Rev Proteomics. 2017 May;14(5):409-418. doi: 10.1080/14789450.2017.1316977. Epub 2017 Apr 17. Review.

49.

Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites.

Coetzee N, Sidoli S, van Biljon R, Painter H, Llinás M, Garcia BA, Birkholtz LM.

Sci Rep. 2017 Apr 4;7(1):607. doi: 10.1038/s41598-017-00687-7.

50.

Photoaffinity Ligand for the Inhalational Anesthetic Sevoflurane Allows Mechanistic Insight into Potassium Channel Modulation.

Woll KA, Peng W, Liang Q, Zhi L, Jacobs JA, Maciunas L, Bhanu N, Garcia BA, Covarrubias M, Loll PJ, Dailey WP, Eckenhoff RG.

ACS Chem Biol. 2017 May 19;12(5):1353-1362. doi: 10.1021/acschembio.7b00222. Epub 2017 Apr 3.

PMID:
28333442

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