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Items: 1 to 50 of 53

1.

Factors Secreted by Cancer-Associated Fibroblasts that Sustain Cancer Stem Properties in Head and Neck Squamous Carcinoma Cells as Potential Therapeutic Targets.

Álvarez-Teijeiro S, García-Inclán C, Villaronga MÁ, Casado P, Hermida-Prado F, Granda-Díaz R, Rodrigo JP, Calvo F, Del-Río-Ibisate N, Gandarillas A, Morís F, Hermsen M, Cutillas P, García-Pedrero JM.

Cancers (Basel). 2018 Sep 17;10(9). pii: E334. doi: 10.3390/cancers10090334.

2.

Mutational profiling can identify laryngeal dysplasia at risk of progression to invasive carcinoma.

Manterola L, Aguirre P, Larrea E, Arestín M, Gaafar A, Elorriaga K, Goicoechea I, Armesto M, Fernández-Mercado M, Zabalza I, López-Duque JC, Larruskain E, Sistiaga JA, Landa M, Zabala A, Santaolalla F, Municio JA, Ispizua Á, García-Pedrero JM, Rodrigo JP, Lawrie CH.

Sci Rep. 2018 Apr 26;8(1):6613. doi: 10.1038/s41598-018-24780-7.

3.

Immunohistochemical Expression of Cortactin and Focal Adhesion Kinase Predicts Recurrence Risk and Laryngeal Cancer Risk Beyond Histologic Grading.

Villaronga MÁ, Hermida-Prado F, Granda-Díaz R, Menéndez ST, Álvarez-Teijeiro S, Quer M, Vilaseca I, Allonca E, Garzón-Arango M, Sanz-Moreno V, Astudillo A, Rodrigo JP, García-Pedrero JM.

Cancer Epidemiol Biomarkers Prev. 2018 Jul;27(7):805-813. doi: 10.1158/1055-9965.EPI-17-1082. Epub 2018 Apr 13.

PMID:
29654156
4.

Analysis of Invasive Activity of CAF Spheroids into Three Dimensional (3D) Collagen Matrices.

Villaronga MÁ, Teijeiro SÁ, Hermida-Prado F, Garzón-Arango M, Sanz-Moreno V, García-Pedrero JM.

Methods Mol Biol. 2018;1731:145-154. doi: 10.1007/978-1-4939-7595-2_14.

PMID:
29318551
5.

Dysregulation of Mir-196b in Head and Neck Cancers Leads to Pleiotropic Effects in the Tumor Cells and Surrounding Stromal Fibroblasts.

Álvarez-Teijeiro S, Menéndez ST, Villaronga MÁ, Rodrigo JP, Manterola L, de Villalaín L, de Vicente JC, Alonso-Durán L, Fernández MP, Lawrie CH, García-Pedrero JM.

Sci Rep. 2017 Dec 19;7(1):17785. doi: 10.1038/s41598-017-18138-8.

6.

FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway.

Tornin J, Hermida-Prado F, Padda RS, Gonzalez MV, Alvarez-Fernandez C, Rey V, Martinez-Cruzado L, Estupiñan O, Menendez ST, Fernandez-Nevado L, Astudillo A, Rodrigo JP, Lucien F, Kim Y, Leong HS, Garcia-Pedrero JM, Rodriguez R.

Neoplasia. 2018 Jan;20(1):44-56. doi: 10.1016/j.neo.2017.11.004. Epub 2017 Nov 28.

7.

A Novel Role For Nanog As An Early Cancer Risk Marker In Patients With Laryngeal Precancerous Lesions.

Rodrigo JP, Villaronga MÁ, Menéndez ST, Hermida-Prado F, Quer M, Vilaseca I, Allonca E, Pedregal Mallo D, Astudillo A, García-Pedrero JM.

Sci Rep. 2017 Sep 11;7(1):11110. doi: 10.1038/s41598-017-11709-9.

8.

Prognostic significance of E-cadherin and β-catenin expression in HPV-negative oropharyngeal squamous cell carcinomas.

García-Pedrero JM, García-Cabo P, Ángeles Villaronga M, Hermida-Prado F, Granda-Díaz R, Allonca E, Rodrigo JP.

Head Neck. 2017 Nov;39(11):2293-2300. doi: 10.1002/hed.24897. Epub 2017 Aug 17.

PMID:
28815780
9.

Annexin A1 down-regulation in head and neck squamous cell carcinoma is mediated via transcriptional control with direct involvement of miR-196a/b.

Álvarez-Teijeiro S, Menéndez ST, Villaronga MÁ, Pena-Alonso E, Rodrigo JP, Morgan RO, Granda-Díaz R, Salom C, Fernandez MP, García-Pedrero JM.

Sci Rep. 2017 Jul 28;7(1):6790. doi: 10.1038/s41598-017-07169-w.

10.

Tumor programmed cell death ligand 1 expression correlates with nodal metastasis in patients with cutaneous squamous cell carcinoma of the head and neck.

García-Pedrero JM, Martínez-Camblor P, Diaz-Coto S, Munguia-Calzada P, Vallina-Alvarez A, Vazquez-Lopez F, Rodrigo JP, Santos-Juanes J.

J Am Acad Dermatol. 2017 Sep;77(3):527-533. doi: 10.1016/j.jaad.2017.05.047. Epub 2017 Jul 14.

PMID:
28716437
11.

Phosphorylated ribosomal protein S6 correlation with p21 expression and inverse association with tumor size in oral squamous cell carcinoma.

de Vicente JC, Peña I, Rodrigo JP, Rodríguez-Santamarta T, Lequerica-Fernández P, Suárez-Fernández L, Allonca E, García-Pedrero JM.

Head Neck. 2017 Sep;39(9):1876-1887. doi: 10.1002/hed.24854. Epub 2017 Jul 4.

PMID:
28675642
12.

Trabectedin and Campthotecin Synergistically Eliminate Cancer Stem Cells in Cell-of-Origin Sarcoma Models.

Martinez-Cruzado L, Tornin J, Rodriguez A, Santos L, Allonca E, Fernandez-Garcia MT, Astudillo A, Garcia-Pedrero JM, Rodriguez R.

Neoplasia. 2017 Jun;19(6):460-470. doi: 10.1016/j.neo.2017.03.004. Epub 2017 May 8.

13.

Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells.

Fontanil T, Álvarez-Teijeiro S, Villaronga MÁ, Mohamedi Y, Solares L, Moncada-Pazos A, Vega JA, García-Suárez O, Pérez-Basterrechea M, García-Pedrero JM, Obaya AJ, Cal S.

Oncotarget. 2017 Feb 21;8(8):13716-13729. doi: 10.18632/oncotarget.14627.

14.

HERG1 potassium channel expression in potentially malignant disorders of the oral mucosa and prognostic relevance in oral squamous cell carcinoma.

Fernández-Valle Á, Rodrigo JP, Rodríguez-Santamarta T, Villaronga MÁ, Álvarez-Teijeiro S, García-Pedrero JM, Suárez-Fernández L, Lequerica-Fernández P, de Vicente JC.

Head Neck. 2016 Nov;38(11):1672-1678. doi: 10.1002/hed.24493. Epub 2016 Apr 30.

PMID:
27131339
15.

A new mechanism of regulation of p21 by the mTORC1/4E-BP1 pathway predicts clinical outcome of head and neck cancer.

Llanos S, García-Pedrero JM.

Mol Cell Oncol. 2016 May 12;3(4):e1159275. doi: 10.1080/23723556.2016.1159275. eCollection 2016 Jul.

16.

Prevalence of human papillomavirus in oral squamous cell carcinomas in northern Spain.

Rodríguez-Santamarta T, Rodrigo JP, García-Pedrero JM, Álvarez-Teijeiro S, Ángeles Villaronga M, Suárez-Fernández L, Alvarez-Argüelles ME, Astudillo A, de Vicente JC.

Eur Arch Otorhinolaryngol. 2016 Dec;273(12):4549-4559. doi: 10.1007/s00405-016-4152-9. Epub 2016 Jun 24.

PMID:
27342404
17.

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas.

García-Carracedo D, Villaronga MÁ, Álvarez-Teijeiro S, Hermida-Prado F, Santamaría I, Allonca E, Suárez-Fernández L, Gonzalez MV, Balbín M, Astudillo A, Martínez-Camblor P, Su GH, Rodrigo JP, García-Pedrero JM.

Oncotarget. 2016 May 17;7(20):29780-93. doi: 10.18632/oncotarget.8957.

18.

Stabilization of p21 by mTORC1/4E-BP1 predicts clinical outcome of head and neck cancers.

Llanos S, García-Pedrero JM, Morgado-Palacin L, Rodrigo JP, Serrano M.

Nat Commun. 2016 Feb 2;7:10438. doi: 10.1038/ncomms10438.

19.

HERG1A potassium channel is the predominant isoform in head and neck squamous cell carcinomas: evidence for regulation by epigenetic mechanisms.

Menéndez ST, Villaronga MÁ, Rodrigo JP, Álvarez-Teijeiro S, Urdinguio RG, Fraga MF, Suárez C, García-Pedrero JM.

Sci Rep. 2016 Jan 20;6:19666. doi: 10.1038/srep19666.

20.

Expression of the voltage-gated potassium channel Kv3.4 in oral leucoplakias and oral squamous cell carcinomas.

Fernández-Valle Á, Rodrigo JP, García-Pedrero JM, Rodríguez-Santamarta T, Allonca E, Lequerica-Fernández P, de Vicente JC.

Histopathology. 2016 Jul;69(1):91-8. doi: 10.1111/his.12917. Epub 2016 Feb 28.

PMID:
26648458
21.

Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis.

Manils J, Gómez D, Salla-Martret M, Fischer H, Fye JM, Marzo E, Marruecos L, Serrano I, Salgado R, Rodrigo JP, Garcia-Pedrero JM, Serafin AM, Cañas X, Benito C, Toll A, Forcales SV, Perrino FW, Eckhart L, Soler C.

Oncotarget. 2015 Sep 8;6(26):22375-96.

22.

Expression of podoplanin in the invasion front of oral squamous cell carcinoma is not prognostic for survival.

de Vicente JC, Santamarta TR, Rodrigo JP, García-Pedrero JM, Allonca E, Blanco-Lorenzo V.

Virchows Arch. 2015 May;466(5):549-58. doi: 10.1007/s00428-015-1746-3. Epub 2015 Mar 1.

PMID:
25726183
23.

Prevalence of human papillomavirus in laryngeal and hypopharyngeal squamous cell carcinomas in northern Spain.

Rodrigo JP, Hermsen MA, Fresno MF, Brakenhoff RH, García-Velasco F, Snijders PJ, Heideman DA, García-Pedrero JM.

Cancer Epidemiol. 2015 Feb;39(1):37-41. doi: 10.1016/j.canep.2014.11.003. Epub 2014 Nov 29.

PMID:
25468644
24.

Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia.

Piazzolla D, Palla AR, Pantoja C, Cañamero M, de Castro IP, Ortega S, Gómez-López G, Dominguez O, Megías D, Roncador G, Luque-Garcia JL, Fernandez-Tresguerres B, Fernandez AF, Fraga MF, Rodriguez-Justo M, Manzanares M, Sánchez-Carbayo M, García-Pedrero JM, Rodrigo JP, Malumbres M, Serrano M.

Nat Commun. 2014 Jun 30;5:4226. doi: 10.1038/ncomms5226.

PMID:
24979572
25.

SOX2 expression in hypopharyngeal, laryngeal, and sinonasal squamous cell carcinoma.

González-Márquez R, Llorente JL, Rodrigo JP, García-Pedrero JM, Álvarez-Marcos C, Suárez C, Hermsen MA.

Hum Pathol. 2014 Apr;45(4):851-7. doi: 10.1016/j.humpath.2013.12.004. Epub 2013 Dec 21.

PMID:
24656096
26.

Immunohistochemical markers of distant metastasis in laryngeal and hypopharyngeal squamous cell carcinomas.

Rodrigo JP, Martínez P, Allonca E, Alonso-Durán L, Suárez C, Astudillo A, García-Pedrero JM.

Clin Exp Metastasis. 2014 Mar;31(3):317-25. doi: 10.1007/s10585-013-9630-5. Epub 2013 Dec 27.

PMID:
24370715
27.

p27 and BCL2 expression predicts response to chemotherapy in head and neck squamous cell carcinomas.

Moreno-Galindo C, Hermsen M, García-Pedrero JM, Fresno MF, Suárez C, Rodrigo JP.

Oral Oncol. 2014 Feb;50(2):128-34. doi: 10.1016/j.oraloncology.2013.10.018. Epub 2013 Nov 13.

PMID:
24239278
28.

Time trends in the prevalence of HPV in oropharyngeal squamous cell carcinomas in northern Spain (1990-2009).

Rodrigo JP, Heideman DA, García-Pedrero JM, Fresno MF, Brakenhoff RH, Díaz Molina JP, Snijders PJ, Hermsen MA.

Int J Cancer. 2014 Jan 15;134(2):487-92. doi: 10.1002/ijc.28355. Epub 2013 Jul 27.

29.

Podoplanin expression in oral leukoplakia: tumorigenic role.

de Vicente JC, Rodrigo JP, Rodriguez-Santamarta T, Lequerica-Fernández P, Allonca E, García-Pedrero JM.

Oral Oncol. 2013 Jun;49(6):598-603. doi: 10.1016/j.oraloncology.2013.02.008. Epub 2013 Mar 7.

PMID:
23473850
30.

Frequent aberrant expression of the human ether à go-go (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implications.

Menéndez ST, Villaronga MA, Rodrigo JP, Alvarez-Teijeiro S, García-Carracedo D, Urdinguio RG, Fraga MF, Pardo LA, Viloria CG, Suárez C, García-Pedrero JM.

J Mol Med (Berl). 2012 Oct;90(10):1173-84. doi: 10.1007/s00109-012-0893-0. Epub 2012 Mar 31.

PMID:
22466864
31.

Role of HERG1 potassium channel in both malignant transformation and disease progression in head and neck carcinomas.

Menéndez ST, Rodrigo JP, Alvarez-Teijeiro S, Villaronga MÁ, Allonca E, Vallina A, Astudillo A, Barros F, Suárez C, García-Pedrero JM.

Mod Pathol. 2012 Aug;25(8):1069-78. doi: 10.1038/modpathol.2012.63. Epub 2012 Mar 30.

32.

Cortactin and focal adhesion kinase as predictors of cancer risk in patients with premalignant oral epithelial lesions.

de Vicente JC, Rodrigo JP, Rodriguez-Santamarta T, Lequerica-Fernández P, Allonca E, García-Pedrero JM.

Oral Oncol. 2012 Jul;48(7):641-6. doi: 10.1016/j.oraloncology.2012.02.004. Epub 2012 Feb 28.

PMID:
22377015
33.

Biomarkers predicting malignant progression of laryngeal epithelial precursor lesions: a systematic review.

Rodrigo JP, García-Pedrero JM, Suárez C, Takes RP, Thompson LD, Slootweg PJ, Woolgar JA, Westra WH, Brakenhoff RH, Rinaldo A, Devaney KO, Williams MD, Gnepp DR, Ferlito A.

Eur Arch Otorhinolaryngol. 2012 Apr;269(4):1073-83. doi: 10.1007/s00405-011-1831-4. Epub 2011 Nov 12. Review.

PMID:
22081098
34.

Cortactin and focal adhesion kinase as predictors of cancer risk in patients with laryngeal premalignancy.

Rodrigo JP, Álvarez-Alija G, Menéndez ST, Mancebo G, Allonca E, García-Carracedo D, Fresno MF, Suárez C, García-Pedrero JM.

Cancer Prev Res (Phila). 2011 Aug;4(8):1333-41. doi: 10.1158/1940-6207.CAPR-10-0338. Epub 2011 Jun 6.

35.

Clinical significance of annexin A2 downregulation in oral squamous cell carcinoma.

Rodrigo JP, Lequerica-Fernández P, Rosado P, Allonca E, García-Pedrero JM, de Vicente JC.

Head Neck. 2011 Dec;33(12):1708-14. doi: 10.1002/hed.21661. Epub 2011 Apr 15.

PMID:
21500302
36.

Regulation of the expression of death receptors and their ligands by melatonin in haematological cancer cell lines and in leukaemia cells from patients.

Casado-Zapico S, Martín V, García-Santos G, Rodríguez-Blanco J, Sánchez-Sánchez AM, Luño E, Suárez C, García-Pedrero JM, Menendez ST, Antolín I, Rodriguez C.

J Pineal Res. 2011 Apr;50(3):345-55. doi: 10.1111/j.1600-079X.2010.00850.x. Epub 2011 Feb 24.

PMID:
21392090
37.

Down-regulation of annexin A1 and A2 protein expression in intestinal-type sinonasal adenocarcinomas.

Rodrigo JP, García-Pedrero JM, Llorente JL, Fresno MF, Allonca E, Suarez C, Hermsen M.

Hum Pathol. 2011 Jan;42(1):88-94. doi: 10.1016/j.humpath.2010.05.017. Epub 2010 Oct 20.

PMID:
20970165
38.

Expression and clinical significance of the Kv3.4 potassium channel subunit in the development and progression of head and neck squamous cell carcinomas.

Menéndez ST, Rodrigo JP, Allonca E, García-Carracedo D, Alvarez-Alija G, Casado-Zapico S, Fresno MF, Rodríguez C, Suárez C, García-Pedrero JM.

J Pathol. 2010 Aug;221(4):402-10. doi: 10.1002/path.2722.

PMID:
20593490
39.

Distinctive clinicopathological associations of amplification of the cortactin gene at 11q13 in head and neck squamous cell carcinomas.

Rodrigo JP, García-Carracedo D, García LA, Menéndez S, Allonca E, González MV, Fresno MF, Suárez C, García-Pedrero JM.

J Pathol. 2009 Mar;217(4):516-23. doi: 10.1002/path.2462.

PMID:
18991334
40.

[Annexin A2 expression in head and neck squamous cell carcinoma].

Rodrigo Tapia JP, Pena Alonso E, García-Pedrero JM, Florentino Fresno M, Suárez Nieto C, Owen Morgan R, Fernández MP.

Acta Otorrinolaringol Esp. 2007 Jun-Jul;58(6):257-62. Spanish.

41.

The SWI/SNF chromatin remodeling subunit BAF57 is a critical regulator of estrogen receptor function in breast cancer cells.

García-Pedrero JM, Kiskinis E, Parker MG, Belandia B.

J Biol Chem. 2006 Aug 11;281(32):22656-64. Epub 2006 Jun 12.

42.

Effect of vinca alkaloids on ERalpha levels and estradiol-induced responses in MCF-7 cells.

Martínez-Campa C, Casado P, Rodríguez R, Zuazua P, García-Pedrero JM, Lazo PS, Ramos S.

Breast Cancer Res Treat. 2006 Jul;98(1):81-9. Epub 2006 Mar 23.

PMID:
16555127
43.

Identification of BAF57 mutations in human breast cancer cell lines.

Kiskinis E, García-Pedrero JM, Villaronga MA, Parker MG, Belandia B.

Breast Cancer Res Treat. 2006 Jul;98(2):191-8. Epub 2006 Mar 15.

44.

Annexin A1 expression in nasopharyngeal carcinoma correlates with squamous differentiation.

Rodrigo JP, Garcia-Pedrero JM, Fernandez MP, Morgan RO, Suárez C, Herrero A.

Am J Rhinol. 2005 Sep-Oct;19(5):483-7.

PMID:
16270603
45.

Hey1, a mediator of notch signaling, is an androgen receptor corepressor.

Belandia B, Powell SM, García-Pedrero JM, Walker MM, Bevan CL, Parker MG.

Mol Cell Biol. 2005 Feb;25(4):1425-36.

46.

[Expression of annexins Al and A2 in the mucosa of the upper airdigestive tract].

Rodrigo Tapia JP, García Pedrero JM, Pena Alonso E, Fernández MP, Morgan RO, Suárez Nieto C, Herrero Zapatero A.

Acta Otorrinolaringol Esp. 2004 Aug-Sep;55(7):310-4. Spanish.

47.

Melatonin, an endogenous-specific inhibitor of estrogen receptor alpha via calmodulin.

del Río B, García Pedrero JM, Martínez-Campa C, Zuazua P, Lazo PS, Ramos S.

J Biol Chem. 2004 Sep 10;279(37):38294-302. Epub 2004 Jun 30.

48.

Expression of annexin A1 in normal and chronically inflamed nasal mucosa.

Rodrigo JP, García-Pedrero JM, González MV, Fernández MP, Suárez C, Herrero A.

Arch Otolaryngol Head Neck Surg. 2004 Feb;130(2):211-5.

PMID:
14967753
49.

Annexin A1 down-regulation in head and neck cancer is associated with epithelial differentiation status.

Garcia Pedrero JM, Fernandez MP, Morgan RO, Herrero Zapatero A, Gonzalez MV, Suarez Nieto C, Rodrigo JP.

Am J Pathol. 2004 Jan;164(1):73-9.

50.

[Detection of herpes simplex virus and Epstein-Barr virus in squamous cell carcinoma of the upper airways and digestive system].

López Llames A, Llorente Pendás JL, Melón S, García Pedrero JM, García Carracedo D, Suárez Nieto C.

Acta Otorrinolaringol Esp. 2003 Aug-Sep;54(7):506-11. Spanish.

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