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Items: 1 to 50 of 79

1.

Matrix metalloproteinase-9 induces a pro-angiogenic profile in chronic lymphocytic leukemia cells.

Aguilera-Montilla N, Bailón E, Ugarte-Berzal E, Uceda-Castro R, Prieto-Solano M, García-Martínez E, Samaniego R, Van den Steen PE, Opdenakker G, García-Marco JA, García-Pardo A.

Biochem Biophys Res Commun. 2019 Nov 26;520(1):198-204. doi: 10.1016/j.bbrc.2019.09.127. Epub 2019 Oct 1.

PMID:
31585732
2.

α4β1 integrin associates with VEGFR2 in CLL cells and contributes to VEGF binding and intracellular signaling.

Gutiérrez-González A, Aguilera-Montilla N, Ugarte-Berzal E, Bailón E, Cerro-Pardo I, Sánchez-Maroto C, García-Campillo L, García-Marco JA, García-Pardo A.

Blood Adv. 2019 Jul 23;3(14):2144-2148. doi: 10.1182/bloodadvances.2019000019. No abstract available.

3.

Molecular Players in Hematologic Tumor Cell Trafficking.

Redondo-Muñoz J, García-Pardo A, Teixidó J.

Front Immunol. 2019 Feb 6;10:156. doi: 10.3389/fimmu.2019.00156. eCollection 2019. Review.

4.

MMP-9 affects gene expression in chronic lymphocytic leukemia revealing CD99 as an MMP-9 target and a novel partner in malignant cell migration/arrest.

Aguilera-Montilla N, Bailón E, Uceda-Castro R, Ugarte-Berzal E, Santos A, Gutiérrez-González A, Pérez-Sánchez C, Van den Steen PE, Opdenakker G, García-Marco JA, García-Pardo A.

Oncogene. 2019 Jun;38(23):4605-4619. doi: 10.1038/s41388-019-0744-3. Epub 2019 Feb 13.

PMID:
30760844
5.

A catalytically inactive gelatinase B/MMP-9 mutant impairs homing of chronic lymphocytic leukemia cells by altering migration regulatory pathways.

Bailón E, Aguilera-Montilla N, Gutiérrez-González A, Ugarte-Berzal E, Van den Steen PE, Opdenakker G, García-Marco JA, García-Pardo A.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):124-130. doi: 10.1016/j.bbrc.2017.10.129. Epub 2017 Nov 4.

PMID:
29080742
6.

Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9.

Amigo-Jiménez I, Bailón E, Aguilera-Montilla N, García-Marco JA, García-Pardo A.

Oncotarget. 2016 Dec 13;7(50):83359-83377. doi: 10.18632/oncotarget.13091.

7.

Evaluation of the potential therapeutic benefits of macrophage reprogramming in multiple myeloma.

Gutiérrez-González A, Martínez-Moreno M, Samaniego R, Arellano-Sánchez N, Salinas-Muñoz L, Relloso M, Valeri A, Martínez-López J, Corbí ÁL, Hidalgo A, García-Pardo Á, Teixidó J, Sánchez-Mateos P.

Blood. 2016 Nov 3;128(18):2241-2252. Epub 2016 Sep 13.

PMID:
27625360
8.

Inhibition of MMP-9-dependent Degradation of Gelatin, but Not Other MMP-9 Substrates, by the MMP-9 Hemopexin Domain Blades 1 and 4.

Ugarte-Berzal E, Vandooren J, Bailón E, Opdenakker G, García-Pardo A.

J Biol Chem. 2016 May 27;291(22):11751-60. doi: 10.1074/jbc.M115.708438. Epub 2016 Apr 4.

9.

In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by α4β1 cytoplasmic-binding proteins.

Martínez-Moreno M, Leiva M, Aguilera-Montilla N, Sevilla-Movilla S, Isern de Val S, Arellano-Sánchez N, Gutiérrez NC, Maldonado R, Martínez-López J, Buño I, García-Marco JA, Sánchez-Mateos P, Hidalgo A, García-Pardo A, Teixidó J.

Leukemia. 2016 Apr;30(4):861-72. doi: 10.1038/leu.2015.332. Epub 2015 Dec 10.

10.

Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways.

Amigo-Jiménez I, Bailón E, Aguilera-Montilla N, Terol MJ, García-Marco JA, García-Pardo A.

Oncotarget. 2015 Dec 29;6(42):44832-48. doi: 10.18632/oncotarget.6265.

11.

Arsenic trioxide synergistically potentiates the cytotoxic effect of fludarabine in chronic lymphocytic leukemia cells by further inactivating the Akt and ERK signaling pathways.

Lozano-Santos C, Amigo-Jiménez I, Nova-Gurumeta S, Pérez-Sanz N, García-Pardo A, García-Marco JA.

Biochem Biophys Res Commun. 2015 May 29;461(2):243-8. doi: 10.1016/j.bbrc.2015.04.007. Epub 2015 Apr 11.

PMID:
25869069
12.

Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1.

Vandooren J, Born B, Solomonov I, Zajac E, Saldova R, Senske M, Ugarte-Berzal E, Martens E, Van den Steen PE, Van Damme J, Garcia-Pardo A, Froeyen M, Deryugina EI, Quigley JP, Moestrup SK, Rudd PM, Sagi I, Opdenakker G.

Biochem J. 2015 Jan 15;465(2):259-70. doi: 10.1042/BJ20140418.

13.

Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.

Bailón E, Ugarte-Berzal E, Amigo-Jiménez I, Van den Steen P, Opdenakker G, García-Marco JA, García-Pardo A.

J Leukoc Biol. 2014 Aug;96(2):185-99. doi: 10.1189/jlb.3HI0913-521R.

PMID:
25080557
14.

Matrix metalloproteinase-9 is involved in chronic lymphocytic leukemia cell response to fludarabine and arsenic trioxide.

Amigo-Jiménez I, Bailón E, Ugarte-Berzal E, Aguilera-Montilla N, García-Marco JA, García-Pardo A.

PLoS One. 2014 Jun 23;9(6):e99993. doi: 10.1371/journal.pone.0099993. eCollection 2014.

15.

A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells.

Ugarte-Berzal E, Bailón E, Amigo-Jiménez I, Albar JP, García-Marco JA, García-Pardo A.

J Biol Chem. 2014 May 30;289(22):15340-9. doi: 10.1074/jbc.M114.559187. Epub 2014 Apr 16.

16.

Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.

Bailón E, Ugarte-Berzal E, Amigo-Jiménez I, Van den Steen P, Opdenakker G, García-Marco JA, García-Pardo A.

J Leukoc Biol. 2014 Mar 11. [Epub ahead of print]

PMID:
24620030
17.

The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway.

Rey-Barroso J, Colo GP, Alvarez-Barrientos A, Redondo-Muñoz J, Carvajal-González JM, Mulero-Navarro S, García-Pardo A, Teixidó J, Fernandez-Salguero PM.

Cell Signal. 2013 Apr;25(4):848-59. doi: 10.1016/j.cellsig.2013.01.010. Epub 2013 Jan 16.

PMID:
23333462
18.

A 17-residue sequence from the matrix metalloproteinase-9 (MMP-9) hemopexin domain binds α4β1 integrin and inhibits MMP-9-induced functions in chronic lymphocytic leukemia B cells.

Ugarte-Berzal E, Bailón E, Amigo-Jiménez I, Vituri CL, del Cerro MH, Terol MJ, Albar JP, Rivas G, García-Marco JA, García-Pardo A.

J Biol Chem. 2012 Aug 10;287(33):27601-13. doi: 10.1074/jbc.M112.354670. Epub 2012 Jun 22.

19.

Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function.

García-Bernal D, Redondo-Muñoz J, Dios-Esponera A, Chèvre R, Bailón E, Garayoa M, Arellano-Sánchez N, Gutierrez NC, Hidalgo A, García-Pardo A, Teixidó J.

J Pathol. 2013 Jan;229(1):36-48. doi: 10.1002/path.4066.

PMID:
22711564
20.

[Esopheal foreign body impaction].

García-Pardo AR, Pérez Díaz D, Machado Liendo PJ, Cortese S, Atahualpa Arenas F, Turégano Fuentes F.

Acta Gastroenterol Latinoam. 2012 Mar;42(1):46-9. Spanish.

PMID:
22616497
21.

Molecular and functional characterization of mouse S5D-SRCRB: a new group B member of the scavenger receptor cysteine-rich superfamily.

Miró-Julià C, Roselló S, Martínez VG, Fink DR, Escoda-Ferran C, Padilla O, Vázquez-Echeverría C, Espinal-Marin P, Pujades C, García-Pardo A, Vila J, Serra-Pagès C, Holmskov U, Yélamos J, Lozano F.

J Immunol. 2011 Feb 15;186(4):2344-54. doi: 10.4049/jimmunol.1000840. Epub 2011 Jan 7.

22.

The CS1 segment of fibronectin is involved in human OSCC pathogenesis by mediating OSCC cell spreading, migration, and invasion.

Kamarajan P, Garcia-Pardo A, D'Silva NJ, Kapila YL.

BMC Cancer. 2010 Jun 25;10:330. doi: 10.1186/1471-2407-10-330.

23.

Induction of B-chronic lymphocytic leukemia cell apoptosis by arsenic trioxide involves suppression of the phosphoinositide 3-kinase/Akt survival pathway via c-jun-NH2 terminal kinase activation and PTEN upregulation.

Redondo-Muñoz J, Escobar-Díaz E, Hernández Del Cerro M, Pandiella A, Terol MJ, García-Marco JA, García-Pardo A.

Clin Cancer Res. 2010 Sep 1;16(17):4382-91. doi: 10.1158/1078-0432.CCR-10-0072. Epub 2010 Jun 9.

24.

Matrix metalloproteinase-9 promotes chronic lymphocytic leukemia b cell survival through its hemopexin domain.

Redondo-Muñoz J, Ugarte-Berzal E, Terol MJ, Van den Steen PE, Hernández del Cerro M, Roderfeld M, Roeb E, Opdenakker G, García-Marco JA, García-Pardo A.

Cancer Cell. 2010 Feb 17;17(2):160-72. doi: 10.1016/j.ccr.2009.12.044.

25.

VEGF/VEGFR2 interaction down-regulates matrix metalloproteinase-9 via STAT1 activation and inhibits B chronic lymphocytic leukemia cell migration.

Ugarte-Berzal E, Redondo-Muñoz J, Eroles P, Del Cerro MH, García-Marco JA, Terol MJ, García-Pardo A.

Blood. 2010 Jan 28;115(4):846-9. doi: 10.1182/blood-2009-08-239426. Epub 2009 Nov 19.

26.

Inadequate activation of the GTPase RhoA contributes to the lack of fibronectin matrix assembly in von Hippel-Lindau protein-defective renal cancer cells.

Feijóo-Cuaresma M, Méndez F, Maqueda A, Esteban MA, Naranjo-Suarez S, Castellanos MC, del Cerro MH, Vazquez SN, García-Pardo A, Landázuri MO, Calzada MJ.

J Biol Chem. 2008 Sep 5;283(36):24982-90. doi: 10.1074/jbc.M709390200. Epub 2008 Jun 19.

27.

Alpha4beta1 integrin and 190-kDa CD44v constitute a cell surface docking complex for gelatinase B/MMP-9 in chronic leukemic but not in normal B cells.

Redondo-Muñoz J, Ugarte-Berzal E, García-Marco JA, del Cerro MH, Van den Steen PE, Opdenakker G, Terol MJ, García-Pardo A.

Blood. 2008 Jul 1;112(1):169-78. doi: 10.1182/blood-2007-08-109249. Epub 2008 Mar 7.

29.

The heparin III-binding domain of fibronectin (III4-5 repeats) binds to fibronectin and inhibits fibronectin matrix assembly.

Maqueda A, Moyano JV, Hernández Del Cerro M, Peters DM, Garcia-Pardo A.

Matrix Biol. 2007 Oct;26(8):642-51. Epub 2007 Jun 14.

PMID:
17611093
30.

MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha4beta1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration.

Redondo-Muñoz J, Escobar-Díaz E, Samaniego R, Terol MJ, García-Marco JA, García-Pardo A.

Blood. 2006 Nov 1;108(9):3143-51. Epub 2006 Jul 13.

PMID:
16840734
31.

[Transmission of Buruli ulcer from person to person].

Marañés Antoñanzas I, López Gallardo Y, García Pardo A, Abella Vázquez ML.

Rev Clin Esp. 2006 May;206(5):256-7. Spanish. No abstract available.

PMID:
16750116
32.

[Uncommon complications in central venous catheterization].

Marañés Antoñanzas I, López Gallardo Y, Abella Vázquez ML, García Pardo A, Bethencourt Feria M.

An Med Interna. 2006 Jan;23(1):47-8. Spanish. No abstract available.

PMID:
16596735
33.

Activation pathways of alpha4beta1 integrin leading to distinct T-cell cytoskeleton reorganization, Rac1 regulation and Pyk2 phosphorylation.

Maqueda A, Moyano JV, Gutiérrez-López MD, Ovalle S, Rodríguez-Frade JM, Cabañas C, Garcia-Pardo A.

J Cell Physiol. 2006 Jun;207(3):746-56.

PMID:
16514607
34.

[Antisynthetase syndrome without myositic disease: a case report].

Marañés Antoñanzas I, López Gallardo Y, García Pardo A, Miguélez Morales M, Abella Vázquez ML, Bethencourt Feria M.

An Med Interna. 2005 Apr;22(4):182-4. Spanish.

PMID:
16004515
35.

AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kappaB survival pathway.

Escobar-Díaz E, López-Martín EM, Hernández del Cerro M, Puig-Kroger A, Soto-Cerrato V, Montaner B, Giralt E, García-Marco JA, Pérez-Tomás R, Garcia-Pardo A.

Leukemia. 2005 Apr;19(4):572-9.

PMID:
15744353
36.

Heparin II domain of fibronectin uses alpha4beta1 integrin to control focal adhesion and stress fiber formation, independent of syndecan-4.

Peterson JA, Sheibani N, David G, Garcia-Pardo A, Peters DM.

J Biol Chem. 2005 Feb 25;280(8):6915-22. Epub 2004 Nov 30.

37.

Bcl-2 family gene modulation during spontaneous apoptosis of B-chronic lymphocytic leukemia cells.

Sanz L, Garcia-Marco JA, Casanova B, de La Fuente MT, García-Gila M, Garcia-Pardo A, Silva A.

Biochem Biophys Res Commun. 2004 Mar 12;315(3):562-7.

PMID:
14975737
38.

Involvement of p53 in alpha4beta1 integrin-mediated resistance of B-CLL cells to fludarabine.

de la Fuente MT, Casanova B, Cantero E, Hernández del Cerro M, Garcia-Marco J, Silva A, Garcia-Pardo A.

Biochem Biophys Res Commun. 2003 Nov 21;311(3):708-12.

PMID:
14623330
39.
40.
41.

Role of the von Hippel-Lindau tumor suppressor gene in the formation of beta1-integrin fibrillar adhesions.

Esteban-Barragán MA, Avila P, Alvarez-Tejado M, Gutiérrez MD, García-Pardo A, Sánchez-Madrid F, Landázuri MO.

Cancer Res. 2002 May 15;62(10):2929-36.

42.
43.

Engagement of alpha4beta1 integrin by fibronectin induces in vitro resistance of B chronic lymphocytic leukemia cells to fludarabine.

de la Fuente MT, Casanova B, Moyano JV, Garcia-Gila M, Sanz L, Garcia-Marco J, Silva A, Garcia-Pardo A.

J Leukoc Biol. 2002 Mar;71(3):495-502.

PMID:
11867687
44.

Interference of tenascin-C with syndecan-4 binding to fibronectin blocks cell adhesion and stimulates tumor cell proliferation.

Huang W, Chiquet-Ehrismann R, Moyano JV, Garcia-Pardo A, Orend G.

Cancer Res. 2001 Dec 1;61(23):8586-94.

45.

The class II tumor-suppressor gene RARRES3 is expressed in B cell lymphocytic leukemias and down-regulated with disease progression.

Casanova B, de la Fuente MT, Garcia-Gila M, Sanz L, Silva A, Garcia-Marco JA, Garcia-Pardo A.

Leukemia. 2001 Oct;15(10):1521-6.

46.

Liver damage using suicide genes. A model for oval cell activation.

Bustos M, Sangro B, Alzuguren P, Gil AG, Ruiz J, Beraza N, Qian C, Garcia-Pardo A, Prieto J.

Am J Pathol. 2000 Aug;157(2):549-59.

47.

Endoglin overexpression modulates cellular morphology, migration, and adhesion of mouse fibroblasts.

Guerrero-Esteo M, Lastres P, Letamendía A, Pérez-Alvarez MJ, Langa C, López LA, Fabra A, García-Pardo A, Vera S, Letarte M, Bernabéu C.

Eur J Cell Biol. 1999 Sep;78(9):614-23.

PMID:
10535303
48.

Fibronectin interaction with alpha4beta1 integrin prevents apoptosis in B cell chronic lymphocytic leukemia: correlation with Bcl-2 and Bax.

de la Fuente MT, Casanova B, Garcia-Gila M, Silva A, Garcia-Pardo A.

Leukemia. 1999 Feb;13(2):266-74.

50.

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