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Items: 8


A Comparative Analysis of the Peptide Repertoires of HLA-DR Molecules Differentially Associated With Rheumatoid Arthritis.

Scholz E, Mestre-Ferrer A, Daura X, García-Medel N, Carrascal M, James EA, Kwok WW, Canals F, Álvarez I.

Arthritis Rheumatol. 2016 Oct;68(10):2412-21. doi: 10.1002/art.39736.


Peptide handling by HLA-B27 subtypes influences their biological behavior, association with ankylosing spondylitis and susceptibility to endoplasmic reticulum aminopeptidase 1 (ERAP1).

García-Medel N, Sanz-Bravo A, Alvarez-Navarro C, Gómez-Molina P, Barnea E, Marcilla M, Admon A, de Castro JA.

Mol Cell Proteomics. 2014 Dec;13(12):3367-80. doi: 10.1074/mcp.M114.039214. Epub 2014 Sep 3.


β-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanism.

Fernández-Arenas E, Calleja E, Martínez-Martín N, Gharbi SI, Navajas R, García-Medel N, Penela P, Alcamí A, Mayor F Jr, Albar JP, Alarcón B.

EMBO J. 2014 Mar 18;33(6):559-77. doi: 10.1002/embj.201386022. Epub 2014 Feb 6.


Diversity of natural self-derived ligands presented by different HLA class I molecules in transporter antigen processing-deficient cells.

Lorente E, Infantes S, Barnea E, Beer I, Barriga A, García-Medel N, Lasala F, Jiménez M, Admon A, López D.

PLoS One. 2013;8(3):e59118. doi: 10.1371/journal.pone.0059118. Epub 2013 Mar 26.


Functional interaction of the ankylosing spondylitis-associated endoplasmic reticulum aminopeptidase 1 polymorphism and HLA-B27 in vivo.

García-Medel N, Sanz-Bravo A, Van Nguyen D, Galocha B, Gómez-Molina P, Martín-Esteban A, Alvarez-Navarro C, de Castro JA.

Mol Cell Proteomics. 2012 Nov;11(11):1416-29. doi: 10.1074/mcp.M112.019588. Epub 2012 Aug 23.


The origin of proteasome-inhibitor resistant HLA class I peptidomes: a study with HLA-A*68:01.

García-Medel N, Sanz-Bravo A, Barnea E, Admon A, López de Castro JA.

Mol Cell Proteomics. 2012 Jan;11(1):M111.011486. doi: 10.1074/mcp.M111.011486. Epub 2011 Oct 3.


Endogenous processing and presentation of T-cell epitopes from Chlamydia trachomatis with relevance in HLA-B27-associated reactive arthritis.

Cragnolini JJ, García-Medel N, de Castro JA.

Mol Cell Proteomics. 2009 Aug;8(8):1850-9. doi: 10.1074/mcp.M900107-MCP200. Epub 2009 May 13.


Presentation of cytosolically stable peptides by HLA-B27 is not dependent on the canonic interactions of N-terminal basic residues in the A pocket.

Gómez P, Mavian C, Galocha B, García-Medel N, López de Castro JA.

J Immunol. 2009 Jan 1;182(1):446-55.

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