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Items: 1 to 50 of 51

1.

Extracellular histones activate autophagy and apoptosis via mTOR signaling in human endothelial cells.

Ibañez-Cabellos JS, Aguado C, Pérez-Cremades D, García-Giménez JL, Bueno-Betí C, García-López EM, Romá-Mateo C, Novella S, Hermenegildo C, Pallardó FV.

Biochim Biophys Acta. 2018 Jul 10. pii: S0925-4439(18)30250-3. doi: 10.1016/j.bbadis.2018.07.010. [Epub ahead of print]

PMID:
30006152
2.

miR-1226 detection in GCF as potential biomarker of chronic periodontitis: A pilot study.

Micó-Martínez P, García-Giménez JL, Seco-Cervera M, López-Roldán A, Almiñana-Pastor PJ, Alpiste-Illueca F, Pallardó FV.

Med Oral Patol Oral Cir Bucal. 2018 May 1;23(3):e308-e314. doi: 10.4317/medoral.22329.

3.

Small RNA-seq analysis of circulating miRNAs to identify phenotypic variability in Friedreich's ataxia patients.

Seco-Cervera M, González-Rodríguez D, Ibáñez-Cabellos JS, Peiró-Chova L, Pallardó FV, García-Giménez JL.

Sci Data. 2018 Mar 6;5:180021. doi: 10.1038/sdata.2018.21.

4.

Circulating miRNAs as diagnostic biomarkers for adolescent idiopathic scoliosis.

García-Giménez JL, Rubio-Belmar PA, Peiró-Chova L, Hervás D, González-Rodríguez D, Ibañez-Cabellos JS, Bas-Hermida P, Mena-Mollá S, García-López EM, Pallardó FV, Bas T.

Sci Rep. 2018 Feb 8;8(1):2646. doi: 10.1038/s41598-018-21146-x.

5.

CCL20 Expression by Tumor-Associated Macrophages Predicts Progression of Human Primary Cutaneous Melanoma.

Samaniego R, Gutiérrez-González A, Gutiérrez-Seijo A, Sánchez-Gregorio S, García-Giménez J, Mercader E, Márquez-Rodas I, Avilés JA, Relloso M, Sánchez-Mateos P.

Cancer Immunol Res. 2018 Jan 23. doi: 10.1158/2326-6066.CIR-17-0198. [Epub ahead of print]

PMID:
29362221
6.

Epigenetic biomarkers: Current strategies and future challenges for their use in the clinical laboratory.

García-Giménez JL, Seco-Cervera M, Tollefsbol TO, Romá-Mateo C, Peiró-Chova L, Lapunzina P, Pallardó FV.

Crit Rev Clin Lab Sci. 2017 Nov - Dec;54(7-8):529-550. doi: 10.1080/10408363.2017.1410520. Epub 2017 Dec 11. Review.

PMID:
29226748
7.

Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.

Ibáñez-Cabellos JS, Pérez-Machado G, Seco-Cervera M, Berenguer-Pascual E, García-Giménez JL, Pallardó FV.

Redox Biol. 2018 Apr;14:398-408. doi: 10.1016/j.redox.2017.10.004. Epub 2017 Oct 7.

8.

A new mass spectrometry-based method for the quantification of histones in plasma from septic shock patients.

García-Giménez JL, Romá-Mateo C, Carbonell N, Palacios L, Peiró-Chova L, García-López E, García-Simón M, Lahuerta R, Gimenez-Garzó C, Berenguer-Pascual E, Mora MI, Valero ML, Alpízar A, Corrales FJ, Blanquer J, Pallardó FV.

Sci Rep. 2017 Sep 6;7(1):10643. doi: 10.1038/s41598-017-10830-z.

9.

Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials.

Victoria-Escandell A, Ibañez-Cabellos JS, de Cutanda SB, Berenguer-Pascual E, Beltrán-García J, García-López E, Pallardó FV, García-Giménez JL, Pallarés-Sabater A, Zarzosa-López I, Monterde M.

Stem Cells Int. 2017;2017:8920356. doi: 10.1155/2017/8920356. Epub 2017 May 24.

10.

Role of glutathione in the regulation of epigenetic mechanisms in disease.

García-Giménez JL, Romá-Mateo C, Pérez-Machado G, Peiró-Chova L, Pallardó FV.

Free Radic Biol Med. 2017 Nov;112:36-48. doi: 10.1016/j.freeradbiomed.2017.07.008. Epub 2017 Jul 10. Review.

PMID:
28705657
11.

Circulating miR-323-3p is a biomarker for cardiomyopathy and an indicator of phenotypic variability in Friedreich's ataxia patients.

Seco-Cervera M, González-Rodríguez D, Ibáñez-Cabellos JS, Peiró-Chova L, González-Cabo P, García-López E, Vílchez JJ, Sanz-Gallego I, Pallardó FV, García-Giménez JL.

Sci Rep. 2017 Jul 12;7(1):5237. doi: 10.1038/s41598-017-04996-9.

12.

Assessing the risk of cytomegalovirus DNAaemia in allogeneic stem cell transplant recipients by monitoring oxidative-stress markers in plasma.

Talaya A, Solano C, Giménez E, García Giménez JL, Vinuesa V, Alberola J, Pallardó FV, Navarro D.

J Gen Virol. 2017 Jul;98(7):1855-1863. doi: 10.1099/jgv.0.000838. Epub 2017 Jul 10.

PMID:
28691896
13.

Oxidative imbalance in low/intermediate-1-risk myelodysplastic syndrome patients: The influence of iron overload.

Ivars D, Orero MT, Javier K, Díaz-Vico L, García-Giménez JL, Mena S, Tormos C, Egea M, Pérez PL, Arrizabalaga B, Ruiz MÁ, Yagüe N, Tormo M, Sancho-Tello R, Gomes A, Algueró C, O'Connor JE, Sáez GT, Carbonell F, Collado R.

Clin Biochem. 2017 Nov;50(16-17):911-917. doi: 10.1016/j.clinbiochem.2017.05.018. Epub 2017 May 29.

PMID:
28571970
14.

Role of p16INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells.

Mas-Bargues C, Viña-Almunia J, Inglés M, Sanz-Ros J, Gambini J, Ibáñez-Cabellos JS, García-Giménez JL, Viña J, Borrás C.

Redox Biol. 2017 Aug;12:690-698. doi: 10.1016/j.redox.2017.04.002. Epub 2017 Apr 7.

15.

Challenges in the analysis of epigenetic biomarkers in clinical samples.

García-Giménez JL, Mena-Mollá S, Beltrán-García J, Sanchis-Gomar F.

Clin Chem Lab Med. 2017 Aug 28;55(10):1474-1477. doi: 10.1515/cclm-2016-1162. Review.

PMID:
28301317
16.

Extracellular histones disarrange vasoactive mediators release through a COX-NOS interaction in human endothelial cells.

Pérez-Cremades D, Bueno-Betí C, García-Giménez JL, Ibañez-Cabellos JS, Hermenegildo C, Pallardó FV, Novella S.

J Cell Mol Med. 2017 Aug;21(8):1584-1592. doi: 10.1111/jcmm.13088. Epub 2017 Feb 28.

17.

A Drosophila model of GDAP1 function reveals the involvement of insulin signalling in the mitochondria-dependent neuromuscular degeneration.

López Del Amo V, Palomino-Schätzlein M, Seco-Cervera M, García-Giménez JL, Pallardó FV, Pineda-Lucena A, Galindo MI.

Biochim Biophys Acta. 2017 Mar;1863(3):801-809. doi: 10.1016/j.bbadis.2017.01.003. Epub 2017 Jan 6.

18.

Biomarkers research in neuromuscular disease Charcot-Marie-Tooth.

Seco-Cervera M, Ibañez-Cabellos JS, Garcia-Gimenez JL, Espinos C, Palau F, Pallardo FV.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S48-9. doi: 10.1016/j.freeradbiomed.2014.10.814. Epub 2014 Dec 10.

PMID:
26461392
19.

Increased oxidative stress and impaired antioxidant response in Lafora disease.

Romá-Mateo C, Aguado C, García-Giménez JL, Ibáñez-Cabellos JS, Seco-Cervera M, Pallardó FV, Knecht E, Sanz P.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S47. doi: 10.1016/j.freeradbiomed.2014.10.809. Epub 2014 Dec 10.

PMID:
26461389
20.

Characterization of the antioxidant systems in different complementation groups of Dyskeratosis Congenita.

Ibañez-Cabellos JS, Seco-Cervera M, Perez-Machado G, Garcia-Gimenez JL, Pallardo FV.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S34. doi: 10.1016/j.freeradbiomed.2014.10.771. Epub 2014 Dec 10.

PMID:
26461348
21.

Glutathione and cellular redox control in epigenetic regulation.

García-Giménez JL, Ibañez-Cabellos JS, Seco-Cervera M, Pallardó FV.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S3. doi: 10.1016/j.freeradbiomed.2014.10.828. Epub 2014 Dec 10.

PMID:
26461333
22.

Oxidative stress, a new hallmark in the pathophysiology of Lafora progressive myoclonus epilepsy.

Romá-Mateo C, Aguado C, García-Giménez JL, Knecht E, Sanz P, Pallardó FV.

Free Radic Biol Med. 2015 Nov;88(Pt A):30-41. doi: 10.1016/j.freeradbiomed.2015.01.034. Epub 2015 Feb 10. Review.

PMID:
25680286
23.

Oxidative stress and mitochondrial dysfunction in Kindler syndrome.

Zapatero-Solana E, García-Giménez JL, Guerrero-Aspizua S, García M, Toll A, Baselga E, Durán-Moreno M, Markovic J, García-Verdugo JM, Conti CJ, Has C, Larcher F, Pallardó FV, Del Rio M.

Orphanet J Rare Dis. 2014 Dec 21;9:211. doi: 10.1186/s13023-014-0211-8.

24.

Mitochondrial defects and neuromuscular degeneration caused by altered expression of Drosophila Gdap1: implications for the Charcot-Marie-Tooth neuropathy.

López Del Amo V, Seco-Cervera M, García-Giménez JL, Whitworth AJ, Pallardó FV, Galindo MI.

Hum Mol Genet. 2015 Jan 1;24(1):21-36. doi: 10.1093/hmg/ddu416. Epub 2014 Aug 13.

PMID:
25122658
25.

Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells.

Manguan-Garcia C, Pintado-Berninches L, Carrillo J, Machado-Pinilla R, Sastre L, Pérez-Quilis C, Esmoris I, Gimeno A, García-Giménez JL, Pallardó FV, Perona R.

PLoS One. 2014 Jul 2;9(7):e101424. doi: 10.1371/journal.pone.0101424. eCollection 2014.

26.

A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability.

Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, Gonzalez-Alvarez I, García-Giménez JL, Díaz Cabañas MJ, Bermejo M, Corma A.

Eur J Med Chem. 2014 Aug 18;83:366-73. doi: 10.1016/j.ejmech.2014.06.050. Epub 2014 Jun 25.

PMID:
24980118
27.

Maintenance of glutathione levels and its importance in epigenetic regulation.

García-Giménez JL, Pallardó FV.

Front Pharmacol. 2014 May 5;5:88. doi: 10.3389/fphar.2014.00088. eCollection 2014. No abstract available.

28.

Increased oxidative stress and impaired antioxidant response in Lafora disease.

Romá-Mateo C, Aguado C, García-Giménez JL, Ibáñez-Cabellos JS, Seco-Cervera M, Pallardó FV, Knecht E, Sanz P.

Mol Neurobiol. 2015;51(3):932-46. doi: 10.1007/s12035-014-8747-0. Epub 2014 May 17.

PMID:
24838580
29.

Oxidative stress and antioxidant response in fibroblasts from Werner and atypical Werner syndromes.

Seco-Cervera M, Spis M, García-Giménez JL, Ibañez-Cabellos JS, Velázquez-Ledesma A, Esmorís I, Bañuls S, Pérez-Machado G, Pallardó FV.

Aging (Albany NY). 2014 Mar;6(3):231-45.

30.

Mitochondrial biogenesis in health and disease. Molecular and therapeutic approaches.

Sanchis-Gomar F, García-Giménez JL, Gómez-Cabrera MC, Pallardó FV.

Curr Pharm Des. 2014;20(35):5619-33. Review.

PMID:
24606801
31.

Physical exercise and epigenetic modulation: elucidating intricate mechanisms.

Pareja-Galeano H, Sanchis-Gomar F, García-Giménez JL.

Sports Med. 2014 Apr;44(4):429-36. doi: 10.1007/s40279-013-0138-6.

PMID:
24399634
32.

Erythropoietin and the heart: physiological effects and the therapeutic perspective.

Sanchis-Gomar F, Garcia-Gimenez JL, Pareja-Galeano H, Romagnoli M, Perez-Quilis C, Lippi G.

Int J Cardiol. 2014 Feb 1;171(2):116-25. doi: 10.1016/j.ijcard.2013.12.011. Epub 2013 Dec 18. Review.

PMID:
24377712
33.

High stability of microRNAs in tissue samples of compromised quality.

Peiró-Chova L, Peña-Chilet M, López-Guerrero JA, García-Giménez JL, Alonso-Yuste E, Burgues O, Lluch A, Ferrer-Lozano J, Ribas G.

Virchows Arch. 2013 Dec;463(6):765-74. doi: 10.1007/s00428-013-1485-2. Epub 2013 Oct 3.

PMID:
24197449
34.

Decreased cell proliferation and higher oxidative stress in fibroblasts from Down Syndrome fetuses. Preliminary study.

Gimeno A, García-Giménez JL, Audí L, Toran N, Andaluz P, Dasí F, Viña J, Pallardó FV.

Biochim Biophys Acta. 2014 Jan;1842(1):116-25. doi: 10.1016/j.bbadis.2013.10.014. Epub 2013 Oct 31.

35.

Lafora disease fibroblasts exemplify the molecular interdependence between thioredoxin 1 and the proteasome in mammalian cells.

García-Giménez JL, Seco-Cervera M, Aguado C, Romá-Mateo C, Dasí F, Priego S, Markovic J, Knecht E, Sanz P, Pallardó FV.

Free Radic Biol Med. 2013 Dec;65:347-59. doi: 10.1016/j.freeradbiomed.2013.07.001. Epub 2013 Jul 9.

PMID:
23850970
36.

Epigenetic biomarkers in laboratory diagnostics: emerging approaches and opportunities.

Sandoval J, Peiró-Chova L, Pallardó FV, García-Giménez JL.

Expert Rev Mol Diagn. 2013 Jun;13(5):457-71. doi: 10.1586/erm.13.37. Review.

PMID:
23782253
37.

Histone h3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure.

García-Giménez JL, Òlaso G, Hake SB, Bönisch C, Wiedemann SM, Markovic J, Dasí F, Gimeno A, Pérez-Quilis C, Palacios O, Capdevila M, Viña J, Pallardó FV.

Antioxid Redox Signal. 2013 Oct 20;19(12):1305-20. doi: 10.1089/ars.2012.5021. Epub 2013 May 21.

38.

DNA binding, nuclease activity, DNA photocleavage and cytotoxic properties of Cu(II) complexes of N-substituted sulfonamides.

García-Giménez JL, Hernández-Gil J, Martínez-Ruíz A, Castiñeiras A, Liu-González M, Pallardó FV, Borrás J, Alzuet Piña G.

J Inorg Biochem. 2013 Apr;121:167-78. doi: 10.1016/j.jinorgbio.2013.01.003. Epub 2013 Jan 11.

PMID:
23384854
39.

Nuclear glutathione.

García-Giménez JL, Markovic J, Dasí F, Queval G, Schnaubelt D, Foyer CH, Pallardó FV.

Biochim Biophys Acta. 2013 May;1830(5):3304-16. doi: 10.1016/j.bbagen.2012.10.005. Epub 2012 Oct 13. Review.

PMID:
23069719
40.

Epigenetic biomarkers: A new perspective in laboratory diagnostics.

García-Giménez JL, Sanchis-Gomar F, Lippi G, Mena S, Ivars D, Gomez-Cabrera MC, Viña J, Pallardó FV.

Clin Chim Acta. 2012 Oct 9;413(19-20):1576-82. doi: 10.1016/j.cca.2012.05.021. Epub 2012 Jun 1. Review.

PMID:
22664147
41.

Physical exercise as an epigenetic modulator: Eustress, the "positive stress" as an effector of gene expression.

Sanchis-Gomar F, Garcia-Gimenez JL, Perez-Quilis C, Gomez-Cabrera MC, Pallardo FV, Lippi G.

J Strength Cond Res. 2012 Dec;26(12):3469-72. doi: 10.1519/JSC.0b013e31825bb594. Review.

PMID:
22561977
42.

Irisin: a new potential hormonal target for the treatment of obesity and type 2 diabetes.

Sanchis-Gomar F, Lippi G, Mayero S, Perez-Quilis C, García-Giménez JL.

J Diabetes. 2012 Sep;4(3):196. doi: 10.1111/j.1753-0407.2012.00194.x. No abstract available.

PMID:
22372821
43.

Histone carbonylation occurs in proliferating cells.

García-Giménez JL, Ledesma AM, Esmoris I, Romá-Mateo C, Sanz P, Viña J, Pallardó FV.

Free Radic Biol Med. 2012 Apr 15;52(8):1453-64. doi: 10.1016/j.freeradbiomed.2012.01.022. Epub 2012 Feb 2.

PMID:
22342519
44.

Differential expression of PGC-1α and metabolic sensors suggest age-dependent induction of mitochondrial biogenesis in Friedreich ataxia fibroblasts.

García-Giménez JL, Gimeno A, Gonzalez-Cabo P, Dasí F, Bolinches-Amorós A, Mollá B, Palau F, Pallardó FV.

PLoS One. 2011;6(6):e20666. doi: 10.1371/journal.pone.0020666. Epub 2011 Jun 7.

45.

Could thiazolidinediones increase the risk of heart failure in Friedreich's ataxia patients?

García-Giménez JL, Sanchis-Gomar F, Pallardó FV.

Mov Disord. 2011 Apr;26(5):769-71. doi: 10.1002/mds.23711. Epub 2011 Apr 5.

PMID:
21469214
46.

Role of glutathione in cell nucleus.

Markovic J, García-Gimenez JL, Gimeno A, Viña J, Pallardó FV.

Free Radic Res. 2010 Jul;44(7):721-33. doi: 10.3109/10715762.2010.485989. Review.

PMID:
20528574
47.

Desmopresssin and hemodilution: implications in doping.

Sanchis-Gomar F, Martinez-Bello VE, Nascimento AL, Perez-Quilis C, Garcia-Gimenez JL, Viña J, Gomez-Cabrera MC.

Int J Sports Med. 2010 Jan;31(1):5-9. doi: 10.1055/s-0029-1239500. Epub 2009 Nov 2.

PMID:
19885778
49.

Oxidative nuclease activity of ferromagnetically coupled mu-hydroxo-mu-propionato copper(II) complexes [Cu3(L)2(mu-OH)2(mu-propionato)2] (L=N-(pyrid-2-ylmethyl)R-sulfonamidato, R=benzene, toluene, naphthalene).

García-Giménez JL, Alzuet G, González-Alvarez M, Liu-González M, Castiñeiras A, Borrás J.

J Inorg Biochem. 2009 Feb;103(2):243-55. doi: 10.1016/j.jinorgbio.2008.10.015. Epub 2008 Oct 30.

PMID:
19054567
50.

A dinuclear copper(II) complex with adeninate bridge ligands and prominent DNA cleavage activity. Structural and spectroscopic characterization and magnetic properties.

García-Giménez JL, Alzuet G, Gonzalez-Alvarez M, Castiñeiras A, Liu-Gonzalez M, Borras J.

Inorg Chem. 2007 Aug 20;46(17):7178-88. Epub 2007 Jul 13.

PMID:
17630687

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