Epidemiological, Clinical and Genetic Study of Hypophosphatasia in A Spanish Population: Identification of Two Novel Mutations in The Alpl Gene.

García-Fontana C, Villa-Suárez JM, Andújar-Vera F, González-Salvatierra S, Martínez-Navajas G, Real PJ, Gómez Vida JM, de Haro T, García-Fontana B, Muñoz-Torres M.

Sci Rep. 2019 Jul 2;9(1):9569. doi: 10.1038/s41598-019-46004-2.


Circulating levels of sclerostin are associated with cardiovascular mortality.

Novo-Rodríguez C, García-Fontana B, Luna-Del Castillo JD, Andújar-Vera F, Ávila-Rubio V, García-Fontana C, Morales-Santana S, Rozas-Moreno P, Muñoz-Torres M.

PLoS One. 2018 Jun 21;13(6):e0199504. doi: 10.1371/journal.pone.0199504. eCollection 2018.


Anthracene drives sub-cellular proteome-wide alterations in the degradative system of Penicillium oxalicum.

Lucero Camacho-Morales R, García-Fontana C, Fernández-Irigoyen J, Santamaría E, González-López J, Manzanera M, Aranda E.

Ecotoxicol Environ Saf. 2018 Sep 15;159:127-135. doi: 10.1016/j.ecoenv.2018.04.051. Epub 2018 May 4.


A New Physiological Role for the DNA Molecule as a Protector against Drying Stress in Desiccation-Tolerant Microorganisms.

García-Fontana C, Narváez-Reinaldo JJ, Castillo F, González-López J, Luque I, Manzanera M.

Front Microbiol. 2016 Dec 22;7:2066. doi: 10.3389/fmicb.2016.02066. eCollection 2016.


Plant Drought Tolerance Enhancement by Trehalose Production of Desiccation-Tolerant Microorganisms.

Vílchez JI, García-Fontana C, Román-Naranjo D, González-López J, Manzanera M.

Front Microbiol. 2016 Sep 30;7:1577. eCollection 2016.


Genome Sequence of Microbacterium sp. Strain 3J1, a Highly Desiccation-Tolerant Bacterium That Promotes Plant Growth.

Manzanera M, García-Fontana C, Vílchez JI, Narváez-Reinaldo JJ, González-López J.

Genome Announc. 2015 Aug 27;3(4). pii: e00713-15. doi: 10.1128/genomeA.00713-15.


Genome Sequence of Arthrobacter koreensis 5J12A, a Plant Growth-Promoting and Desiccation-Tolerant Strain.

Manzanera M, Narváez-Reinaldo JJ, García-Fontana C, Vílchez JI, González-López J.

Genome Announc. 2015 Jun 11;3(3). pii: e00648-15. doi: 10.1128/genomeA.00648-15.


Genome Sequence of Rhodococcus sp. 4J2A2, a Desiccation-Tolerant Bacterium Involved in Biodegradation of Aromatic Hydrocarbons.

Manzanera M, García-Fontana C, Vílchez JI, González-López J.

Genome Announc. 2015 Jun 4;3(3). pii: e00592-15. doi: 10.1128/genomeA.00592-15.


Genome Sequence of Leucobacter sp. 4J7B1, a Plant-Osmoprotectant Soil Microorganism.

Manzanera M, Vílchez JI, García-Fontana C, Calvo C, González-López J.

Genome Announc. 2015 May 21;3(3). pii: e00398-15. doi: 10.1128/genomeA.00398-15.


Multiple signals modulate the activity of the complex sensor kinase TodS.

Silva-Jiménez H, Ortega Á, García-Fontana C, Ramos JL, Krell T.

Microb Biotechnol. 2015 Jan;8(1):103-15. doi: 10.1111/1751-7915.12142. Epub 2014 Jul 1.


Genome Sequence of Arthrobacter siccitolerans 4J27, a Xeroprotectant-Producing Desiccation-Tolerant Microorganism.

Manzanera M, Santa-Cruz-Calvo L, Vílchez JI, García-Fontana C, Silva-Castro GA, Calvo C, González-López J.

Genome Announc. 2014 Jun 19;2(3). pii: e00526-14. doi: 10.1128/genomeA.00526-14.


Characterization of molecular interactions using isothermal titration calorimetry.

Krell T, Lacal J, García-Fontana C, Silva-Jiménez H, Rico-Jiménez M, Lugo AC, Darias JA, Ramos JL.

Methods Mol Biol. 2014;1149:193-203. doi: 10.1007/978-1-4939-0473-0_16.


Qualitative and quantitative assays for flagellum-mediated chemotaxis.

Darias JA, García-Fontana C, Lugo AC, Rico-Jiménez M, Krell T.

Methods Mol Biol. 2014;1149:87-97. doi: 10.1007/978-1-4939-0473-0_10.


Specificity of the CheR2 methyltransferase in Pseudomonas aeruginosa is directed by a C-terminal pentapeptide in the McpB chemoreceptor.

García-Fontana C, Corral Lugo A, Krell T.

Sci Signal. 2014 Apr 8;7(320):ra34. doi: 10.1126/scisignal.2004849.


High specificity in CheR methyltransferase function: CheR2 of Pseudomonas putida is essential for chemotaxis, whereas CheR1 is involved in biofilm formation.

García-Fontana C, Reyes-Darias JA, Muñoz-Martínez F, Alfonso C, Morel B, Ramos JL, Krell T.

J Biol Chem. 2013 Jun 28;288(26):18987-99. doi: 10.1074/jbc.M113.472605. Epub 2013 May 15.


Paralogous chemoreceptors mediate chemotaxis towards protein amino acids and the non-protein amino acid gamma-aminobutyrate (GABA).

Rico-Jiménez M, Muñoz-Martínez F, García-Fontana C, Fernandez M, Morel B, Ortega A, Ramos JL, Krell T.

Mol Microbiol. 2013 Jun;88(6):1230-43. doi: 10.1111/mmi.12255. Epub 2013 May 22.


Tactic responses to pollutants and their potential to increase biodegradation efficiency.

Lacal J, Reyes-Darias JA, García-Fontana C, Ramos JL, Krell T.

J Appl Microbiol. 2013 Apr;114(4):923-33. doi: 10.1111/jam.12076. Epub 2012 Dec 18. Review.


Genes encoding Cher-TPR fusion proteins are predominantly found in gene clusters encoding chemosensory pathways with alternative cellular functions.

Muñoz-Martínez F, García-Fontana C, Rico-Jiménez M, Alfonso C, Krell T.

PLoS One. 2012;7(9):e45810. doi: 10.1371/journal.pone.0045810. Epub 2012 Sep 20.


Responses of Pseudomonas putida to toxic aromatic carbon sources.

Krell T, Lacal J, Guazzaroni ME, Busch A, Silva-Jiménez H, Fillet S, Reyes-Darías JA, Muñoz-Martínez F, Rico-Jiménez M, García-Fontana C, Duque E, Segura A, Ramos JL.

J Biotechnol. 2012 Jul 31;160(1-2):25-32. doi: 10.1016/j.jbiotec.2012.01.026. Epub 2012 Feb 1.


Study of the TmoS/TmoT two-component system: towards the functional characterization of the family of TodS/TodT like systems.

Silva-Jiménez H, García-Fontana C, Cadirci BH, Ramos-González MI, Ramos JL, Krell T.

Microb Biotechnol. 2012 Jul;5(4):489-500. doi: 10.1111/j.1751-7915.2011.00322.x. Epub 2011 Dec 27.


Physiologically relevant divalent cations modulate citrate recognition by the McpS chemoreceptor.

Lacal J, García-Fontana C, Callejo-García C, Ramos JL, Krell T.

J Mol Recognit. 2011 Mar-Apr;24(2):378-85. doi: 10.1002/jmr.1101.


Diversity at its best: bacterial taxis.

Krell T, Lacal J, Muñoz-Martínez F, Reyes-Darias JA, Cadirci BH, García-Fontana C, Ramos JL.

Environ Microbiol. 2011 May;13(5):1115-24. doi: 10.1111/j.1462-2920.2010.02383.x. Epub 2010 Nov 18. Review.


Sensing of environmental signals: classification of chemoreceptors according to the size of their ligand binding regions.

Lacal J, García-Fontana C, Muñoz-Martínez F, Ramos JL, Krell T.

Environ Microbiol. 2010 Nov;12(11):2873-84. doi: 10.1111/j.1462-2920.2010.02325.x. Epub 2010 Aug 25. Review.


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