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Items: 1 to 50 of 51

1.

Detection of genetic purging and predictive value of purging parameters estimated in pedigreed populations.

López-Cortegano E, Bersabé D, Wang J, García-Dorado A.

Heredity (Edinb). 2018 Jul;121(1):38-51. doi: 10.1038/s41437-017-0045-y. Epub 2018 Feb 13.

2.

An explicit model for the inbreeding load in the evolutionary analysis of selfing.

García-Dorado A.

Evolution. 2017 May;71(5):1381-1389. doi: 10.1111/evo.13231. Epub 2017 Apr 10.

PMID:
28323327
3.

Understanding Inbreeding Depression, Purging, and Genetic Rescue.

Hedrick PW, Garcia-Dorado A.

Trends Ecol Evol. 2016 Dec;31(12):940-952. doi: 10.1016/j.tree.2016.09.005. Epub 2016 Oct 12. Review.

PMID:
27743611
4.

Predictive Model and Software for Inbreeding-Purging Analysis of Pedigreed Populations.

García-Dorado A, Wang J, López-Cortegano E.

G3 (Bethesda). 2016 Nov 8;6(11):3593-3601. doi: 10.1534/g3.116.032425.

5.

Estimation of genetic purging under competitive conditions.

López-Cortegano E, Vilas A, Caballero A, García-Dorado A.

Evolution. 2016 Aug;70(8):1856-70. doi: 10.1111/evo.12983. Epub 2016 Jul 5.

PMID:
27302839
6.

On the Consequences of Purging and Linkage on Fitness and Genetic Diversity.

Bersabé D, Caballero A, Pérez-Figueroa A, García-Dorado A.

G3 (Bethesda). 2015 Nov 12;6(1):171-81. doi: 10.1534/g3.115.023184.

7.

On the consequences of ignoring purging on genetic recommendations for minimum viable population rules.

García-Dorado A.

Heredity (Edinb). 2015 Sep;115(3):185-7. doi: 10.1038/hdy.2015.28. Epub 2015 Apr 15. No abstract available.

8.

The action of stabilizing selection, mutation, and drift on epistatic quantitative traits.

Avila V, Pérez-Figueroa A, Caballero A, Hill WG, García-Dorado A, López-Fanjul C.

Evolution. 2014 Jul;68(7):1974-87. doi: 10.1111/evo.12413. Epub 2014 May 5.

PMID:
24689841
9.

Allelic diversity and its implications for the rate of adaptation.

Caballero A, García-Dorado A.

Genetics. 2013 Dec;195(4):1373-84. doi: 10.1534/genetics.113.158410. Epub 2013 Oct 11.

10.

On the genetic parameter determining the efficiency of purging: an estimate for Drosophila egg-to-pupae viability.

Bersabé D, García-Dorado A.

J Evol Biol. 2013 Feb;26(2):375-85. doi: 10.1111/jeb.12054. Epub 2012 Nov 30.

11.

Understanding and predicting the fitness decline of shrunk populations: inbreeding, purging, mutation, and standard selection.

García-Dorado A.

Genetics. 2012 Apr;190(4):1461-76. doi: 10.1534/genetics.111.135541. Epub 2012 Jan 31. Erratum in: Genetics. 2013 Oct;195(2):621.

12.

The fuel of evolution.

López-Fanjul C, García-Dorado A.

Heredity (Edinb). 2011 Apr;106(4):535-6. doi: 10.1038/hdy.2010.110. Epub 2010 Aug 25. Review. No abstract available.

13.

The purge of genetic load through restricted panmixia in a Drosophila experiment.

Avila V, Amador C, García-Dorado A.

J Evol Biol. 2010 Sep 1;23(9):1937-46. doi: 10.1111/j.1420-9101.2010.02058.x. Epub 2010 Jul 31.

14.

Regeneration of the variance of metric traits by spontaneous mutation in a Drosophila population.

Amador C, García-Dorado A, Bersabé D, López-Fanjul C.

Genet Res (Camb). 2010 Apr;92(2):91-102. doi: 10.1017/S001667231000011X.

PMID:
20515513
15.

The action of purifying selection, mutation and drift on fitness epistatic systems.

Pérez-Figueroa A, Caballero A, García-Dorado A, López-Fanjul C.

Genetics. 2009 Sep;183(1):299-313. doi: 10.1534/genetics.109.104893. Epub 2009 Jul 13.

16.

A simple method to account for natural selection when predicting inbreeding depression.

García-Dorado A.

Genetics. 2008 Nov;180(3):1559-66. doi: 10.1534/genetics.108.090597. Epub 2008 Sep 14.

17.
19.

The build up of mutation-selection- drift balance in laboratory Drosophila populations.

García-Dorado A, Avila V, Sánchez-Molano E, Manrique A, López-Fanjul C.

Evolution. 2007 Mar;61(3):653-65.

PMID:
17348928
20.

Increase of the spontaneous mutation rate in a long-term experiment with Drosophila melanogaster.

Avila V, Chavarrías D, Sánchez E, Manrique A, López-Fanjul C, García-Dorado A.

Genetics. 2006 May;173(1):267-77. Epub 2006 Mar 17.

21.

The effect of antagonistic pleiotropy on the estimation of the average coefficient of dominance of deleterious mutations.

Fernández B, García-Dorado A, Caballero A.

Genetics. 2005 Dec;171(4):2097-112. Epub 2005 Aug 22.

22.

A measure of the within-chromosome synergistic epistasis for Drosophila viability.

Rosa JM, Camacho S, García-Dorado A.

J Evol Biol. 2005 Jul;18(4):1130-7.

23.

Inferences on the role of insertion in a mutation accumulation experiment with Drosophila melanogaster using RAPDs.

Salgado C, Nieto B, Toro MA, López-Fanjul C, García-Dorado A.

J Hered. 2005 Sep-Oct;96(5):576-81. Epub 2005 Jul 1.

PMID:
15994415
24.

Maximum likelihood vs. minimum distance: searching for hills in the plain.

García-Dorado A, Gallego A.

Genetics. 2004 Oct;168(2):1085-6. No abstract available.

25.

Analysis of the estimators of the average coefficient of dominance of deleterious mutations.

Fernández B, García-Dorado A, Caballero A.

Genetics. 2004 Oct;168(2):1053-69.

26.

On the persistence and pervasiveness of a new mutation.

García-Dorado A, Caballero A, Crow JF.

Evolution. 2003 Nov;57(11):2644-6.

PMID:
14686539
27.

Comparing analysis methods for mutation-accumulation data: a simulation study.

García-Dorado A, Gallego A.

Genetics. 2003 Jun;164(2):807-19.

28.

The mutational rate of Drosophila viability decline: tinkering with old data.

García-Dorado A, Caballero A.

Genet Res. 2002 Oct;80(2):99-105.

PMID:
12534213
29.

Accumulation of deleterious mutations: additional Drosophila melanogaster estimates and a simulation of the effects of selection.

Caballero A, Cusi E, García C, García-Dorado A.

Evolution. 2002 Jun;56(6):1150-9.

PMID:
12144016
31.

On the average coefficient of dominance of deleterious spontaneous mutations.

García-Dorado A, Caballero A.

Genetics. 2000 Aug;155(4):1991-2001.

32.

Temporal uniformity of the spontaneous mutational variance of quantitative traits in Drosophila melanogaster.

García-Dorado A, Fernández J, López-Fanjul C.

Genet Res. 2000 Feb;75(1):47-51.

PMID:
10740920
33.

Properties of spontaneous mutations affecting quantitative traits.

García-Dorado A, López-Fanjul C, Caballero A.

Genet Res. 1999 Dec;74(3):341-50. Review.

PMID:
10689810
34.

Minimum distance estimation of mutational parameters for quantitative traits.

García-Dorado A, Marín JM.

Biometrics. 1998 Sep;54(3):1097-114.

PMID:
9750255
35.

The mutation rate and the distribution of mutational effects of viability and fitness in Drosophila melanogaster.

García-Dorado A, Monedero JL, López-Fanjul C.

Genetica. 1998;102-103(1-6):255-65.

PMID:
9720284
36.

Population genetics: surviving under mutation pressure.

Keightley PD, Caballero A, García-Dorado A.

Curr Biol. 1998 Mar 26;8(7):R235-7. Review.

37.

THE RATE AND EFFECTS DISTRIBUTION OF VIABILITY MUTATION IN DROSOPHILA: MINIMUM DISTANCE ESTIMATION.

García-Dorado A.

Evolution. 1997 Aug;51(4):1130-1139. doi: 10.1111/j.1558-5646.1997.tb03960.x.

PMID:
28565472
38.

STABILIZING SELECTION DETECTED FOR BRISTLE NUMBER IN DROSOPHILA MELANOGASTER.

García-Dorado A, González JA.

Evolution. 1996 Aug;50(4):1573-1578. doi: 10.1111/j.1558-5646.1996.tb03929.x.

PMID:
28565719
39.

THE GENETICS OF VIABILITY IN DROSOPHILA MELANOGASTER: EFFECTS OF INBREEDING AND ARTIFICIAL SELECTION.

García N, López-Fanjul C, García-Dorado A.

Evolution. 1994 Aug;48(4):1277-1285. doi: 10.1111/j.1558-5646.1994.tb05312.x.

PMID:
28564480
40.

Filling a gap in the prediction of the equilibrium genetic variance.

García-Dorado A.

Theor Popul Biol. 1993 Oct;44(2):177-88.

PMID:
8248886
41.

On the use of the classical tests for detecting linkage.

García-Dorado A, Gallego A.

J Hered. 1992 Mar-Apr;83(2):143-6.

PMID:
1578105
42.

Soft selection and quantitative genetic variation: a laboratory experiment.

García-Dorado A, Martin P, García N.

Heredity (Edinb). 1991 Jun;66 ( Pt 3):313-23.

PMID:
1908838
43.
44.

THE EFFECT OF SOFT SELECTION ON THE VARIABILITY OF A QUANTITATIVE TRAIT.

García-Dorado A.

Evolution. 1990 Feb;44(1):168-179. doi: 10.1111/j.1558-5646.1990.tb04287.x.

PMID:
28568210
45.

Myocardial reperfusion in the pig heart model: infarct size and duration of coronary occlusion.

Garcia-Dorado D, Théroux P, Elizaga J, Galiñanes M, Solares J, Riesgo M, Gomez MJ, Garcia-Dorado A, Fernandez Aviles F.

Cardiovasc Res. 1987 Jul;21(7):537-44.

PMID:
3677143
46.

THE EFFECT OF NICHE PREFERENCE ON POLYMORPHISM PROTECTION IN A HETEROGENEOUS ENVIRONMENT.

Garcia-Dorado A.

Evolution. 1986 Sep;40(5):936-945. doi: 10.1111/j.1558-5646.1986.tb00562.x.

PMID:
28556209
47.

Evolution de l'effectif génétique de lignées de Drosophila melanogaster soumises à une sélection artificielle.

Gallego A, García-Dorado A.

Genet Sel Evol. 1986;18(3):249-60. doi: 10.1186/1297-9686-18-3-249. French. No abstract available.

48.

[Study of the diastolic function of the left ventricle using ultrasonic Doppler examination].

García-Dorado D, San Román D, Elízaga J, Desco M, Domínguez P, Bitini M, Fernández-Avilés F, García-Dorado A.

Rev Esp Cardiol. 1986;39 Suppl 2:54-60. Spanish. No abstract available.

PMID:
3823570
49.

Mitral valve prolapse secondary to right ventricular enlargement in patients with pulmonary hypertension after toxic rapeseed oil ingestion.

García-Dorado D, García EJ, Bello L, Maroto E, Almazán A, Gomez A, Fernández-Aviles F, García-Dorado A.

Eur Heart J. 1985 Jan;6(1):85-90.

PMID:
3159573
50.

Accumulation of lethals in highly selected lines of Drosophila melanogaster.

García-Dorado A, López-Fanjul C.

Theor Appl Genet. 1983 Sep;66(3-4):221-3. doi: 10.1007/BF00251148.

PMID:
24263920

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