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[Acute Abdominal Pain: Hospital Admission or Not - And What Happens Then?]

Garbe J, Michl P, Klement A.

Dtsch Med Wochenschr. 2019 May;144(10):670-676. doi: 10.1055/a-0759-8022. Epub 2019 May 13. German.


Measuring sequencer size bias using REcount: a novel method for highly accurate Illumina sequencing-based quantification.

Gohl DM, Magli A, Garbe J, Becker A, Johnson DM, Anderson S, Auch B, Billstein B, Froehling E, McDevitt SL, Beckman KB.

Genome Biol. 2019 Apr 29;20(1):85. doi: 10.1186/s13059-019-1691-6.


EditR: A Method to Quantify Base Editing from Sanger Sequencing.

Kluesner MG, Nedveck DA, Lahr WS, Garbe JR, Abrahante JE, Webber BR, Moriarity BS.

CRISPR J. 2018 Jun;1:239-250. doi: 10.1089/crispr.2018.0014.


Different culture media modulate growth, heterogeneity, and senescence in human mammary epithelial cell cultures.

Lee JK, Bloom J, Zubeldia-Plazaola A, Garbe JC, Stampfer MR, LaBarge MA.

PLoS One. 2018 Oct 1;13(10):e0204645. doi: 10.1371/journal.pone.0204645. eCollection 2018.


Import Testing: An Outdated Practice? Opportunities for Improved Access to Safe and Efficient Medicines.

Garbe JHO, Jacobs MG, Rönninger SK.

Ther Innov Regul Sci. 2017 Sep;51(5):620-624. doi: 10.1177/2168479017701980. Epub 2017 Apr 7.


Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance.

Jokela TA, Engelsen AST, Rybicka A, Pelissier Vatter FA, Garbe JC, Miyano M, Tiron C, Ferariu D, Akslen LA, Stampfer MR, Lorens JB, LaBarge MA.

Front Cell Dev Biol. 2018 Apr 17;6:41. doi: 10.3389/fcell.2018.00041. eCollection 2018.


A multitask clustering approach for single-cell RNA-seq analysis in Recessive Dystrophic Epidermolysis Bullosa.

Zhang H, Lee CAA, Li Z, Garbe JR, Eide CR, Petegrosso R, Kuang R, Tolar J.

PLoS Comput Biol. 2018 Apr 9;14(4):e1006053. doi: 10.1371/journal.pcbi.1006053. eCollection 2018 Apr.


Severe Colitis After an Alcohol Enema.

Rosendahl J, Michl P, Kleeff J, Wohlgemuth WA, Garbe J.

Am J Gastroenterol. 2018 Feb;113(2):172. doi: 10.1038/ajg.2017.460. No abstract available.


Modern science for better quality control of medicinal products "Towards global harmonization of 3Rs in biologicals": The report of an EPAA workshop.

Schutte K, Szczepanska A, Halder M, Cussler K, Sauer UG, Stirling C, Uhlrich S, Wilk-Zasadna I, John D, Bopst M, Garbe J, Glansbeek HL, Levis R, Serreyn PJ, Smith D, Stickings P.

Biologicals. 2017 Jul;48:55-65. doi: 10.1016/j.biologicals.2017.05.006. Epub 2017 Jun 7.


Femoropopliteal In-stent Restenosis Repair: Midterm Outcomes After Paclitaxel Eluting Balloon Use (PLAISIR Trial).

Bague N, Julia P, Sauguet A, Pernès JM, Chatelard P, Garbé JF, Penillon S, Cardon JM, Commeau P, Planché O, Guyomarch B, Gouëffic Y.

Eur J Vasc Endovasc Surg. 2017 Jan;53(1):106-113. doi: 10.1016/j.ejvs.2016.10.002. Epub 2016 Nov 24.


Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior.

Scott MC, Tomiyasu H, Garbe JR, Cornax I, Amaya C, O'Sullivan MG, Subramanian S, Bryan BA, Modiano JF.

Dis Model Mech. 2016 Dec 1;9(12):1435-1444. Epub 2016 Nov 3.


Chromatin remodeling regulates catalase expression during cancer cells adaptation to chronic oxidative stress.

Glorieux C, Sandoval JM, Fattaccioli A, Dejeans N, Garbe JC, Dieu M, Verrax J, Renard P, Huang P, Calderon PB.

Free Radic Biol Med. 2016 Oct;99:436-450. doi: 10.1016/j.freeradbiomed.2016.08.031. Epub 2016 Aug 31.


Genomic Inbreeding and Relatedness in Wild Panda Populations.

Garbe JR, Prakapenka D, Tan C, Da Y.

PLoS One. 2016 Aug 5;11(8):e0160496. doi: 10.1371/journal.pone.0160496. eCollection 2016.


Systematic improvement of amplicon marker gene methods for increased accuracy in microbiome studies.

Gohl DM, Vangay P, Garbe J, MacLean A, Hauge A, Becker A, Gould TJ, Clayton JB, Johnson TJ, Hunter R, Knights D, Beckman KB.

Nat Biotechnol. 2016 Sep;34(9):942-9. doi: 10.1038/nbt.3601. Epub 2016 Jul 25.


184AA3: a xenograft model of ER+ breast adenocarcinoma.

Hines WC, Kuhn I, Thi K, Chu B, Stanford-Moore G, Sampayo R, Garbe JC, Stampfer M, Borowsky AD, Bissell MJ.

Breast Cancer Res Treat. 2016 Jan;155(1):37-52. doi: 10.1007/s10549-015-3649-z. Epub 2015 Dec 12.


A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers.

Vrba L, Garbe JC, Stampfer MR, Futscher BW.

Epigenetics. 2015;10(11):1074-83. doi: 10.1080/15592294.2015.1106673.


The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans.

Lowe R, Overhoff MG, Ramagopalan SV, Garbe JC, Koh J, Stampfer MR, Beach DH, Rakyan VK, Bishop CL.

Genome Biol. 2015 Sep 17;16:194. doi: 10.1186/s13059-015-0748-4.


Programmed synthesis of three-dimensional tissues.

Todhunter ME, Jee NY, Hughes AJ, Coyle MC, Cerchiari A, Farlow J, Garbe JC, LaBarge MA, Desai TA, Gartner ZJ.

Nat Methods. 2015 Oct;12(10):975-81. doi: 10.1038/nmeth.3553. Epub 2015 Aug 31.


Delineating transcriptional networks of prognostic gene signatures refines treatment recommendations for lymph node-negative breast cancer patients.

Lanigan F, Brien GL, Fan Y, Madden SF, Jerman E, Maratha A, Aloraifi F, Hokamp K, Dunne EJ, Lohan AJ, Flanagan L, Garbe JC, Stampfer MR, Fridberg M, Jirstrom K, Quinn CM, Loftus B, Gallagher WM, Geraghty J, Bracken AP.

FEBS J. 2015 Sep;282(18):3455-73. doi: 10.1111/febs.13354. Epub 2015 Jul 14.


Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells.

Lee JK, Garbe JC, Vrba L, Miyano M, Futscher BW, Stampfer MR, LaBarge MA.

Front Cell Dev Biol. 2015 Mar 11;3:13. doi: 10.3389/fcell.2015.00013. eCollection 2015.


A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity.

Cerchiari AE, Garbe JC, Jee NY, Todhunter ME, Broaders KE, Peehl DM, Desai TA, LaBarge MA, Thomson M, Gartner ZJ.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2287-92. doi: 10.1073/pnas.1410776112. Epub 2015 Jan 29.


Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations.

Garbe JC, Vrba L, Sputova K, Fuchs L, Novak P, Brothman AR, Jackson M, Chin K, LaBarge MA, Watts G, Futscher BW, Stampfer MR.

Cell Cycle. 2014;13(21):3423-35. doi: 10.4161/15384101.2014.954456.


Formation of spatially and geometrically controlled three-dimensional tissues in soft gels by sacrificial micromolding.

Cerchiari A, Garbe JC, Todhunter ME, Jee NY, Pinney JR, LaBarge MA, Desai TA, Gartner ZJ.

Tissue Eng Part C Methods. 2015 Jun;21(6):541-7. doi: 10.1089/ten.TEC.2014.0450. Epub 2014 Dec 11.


Historical data analyses and scientific knowledge suggest complete removal of the abnormal toxicity test as a quality control test.

Garbe JHO, Ausborn S, Beggs C, Bopst M, Joos A, Kitashova AA, Kovbasenco O, Schiller CD, Schwinger M, Semenova N, Smirnova L, Stodart F, Visalli T, Vromans L.

J Pharm Sci. 2014 Nov;103(11):3349-3355. doi: 10.1002/jps.24125. Epub 2014 Sep 10. Review.


Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors.

Pelissier FA, Garbe JC, Ananthanarayanan B, Miyano M, Lin C, Jokela T, Kumar S, Stampfer MR, Lorens JB, LaBarge MA.

Cell Rep. 2014 Jun 26;7(6):1926-39. doi: 10.1016/j.celrep.2014.05.021. Epub 2014 Jun 5.


EndoE from Enterococcus faecalis hydrolyzes the glycans of the biofilm inhibiting protein lactoferrin and mediates growth.

Garbe J, Sjögren J, Cosgrave EF, Struwe WB, Bober M, Olin AI, Rudd PM, Collin M.

PLoS One. 2014 Mar 7;9(3):e91035. doi: 10.1371/journal.pone.0091035. eCollection 2014.


Cellular senescence mediated by p16INK4A-coupled miRNA pathways.

Overhoff MG, Garbe JC, Koh J, Stampfer MR, Beach DH, Bishop CL.

Nucleic Acids Res. 2014 Feb;42(3):1606-18. doi: 10.1093/nar/gkt1096. Epub 2013 Nov 11.


Efficient nonmeiotic allele introgression in livestock using custom endonucleases.

Tan W, Carlson DF, Lancto CA, Garbe JR, Webster DA, Hackett PB, Fahrenkrug SC.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16526-31. doi: 10.1073/pnas.1310478110. Epub 2013 Sep 6.


Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length.

Sputova K, Garbe JC, Pelissier FA, Chang E, Stampfer MR, LaBarge MA.

Genome Integr. 2013 May 29;4(1):4. doi: 10.1186/2041-9414-4-4.


Preliminary experimental study of a mechanical connector allowing vascular anastomosis.

Abou Taam S, Garbé JF, Boufi M, Berdah S, Bossavy JP.

Ann Vasc Surg. 2013 Jul;27(5):638-45. doi: 10.1016/j.avsg.2012.11.003. Epub 2013 Feb 10.


Processing of human reduction mammoplasty and mastectomy tissues for cell culture.

Labarge MA, Garbe JC, Stampfer MR.

J Vis Exp. 2013 Jan 3;(71). pii: 50011. doi: 10.3791/50011.


Cell-type specific DNA methylation patterns define human breast cellular identity.

Novak P, Stampfer MR, Munoz-Rodriguez JL, Garbe JC, Ehrich M, Futscher BW, Jensen TJ.

PLoS One. 2012;7(12):e52299. doi: 10.1371/journal.pone.0052299. Epub 2012 Dec 20.


Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.

Garbe JC, Pepin F, Pelissier FA, Sputova K, Fridriksdottir AJ, Guo DE, Villadsen R, Park M, Petersen OW, Borowsky AD, Stampfer MR, Labarge MA.

Cancer Res. 2012 Jul 15;72(14):3687-701. doi: 10.1158/0008-5472.CAN-12-0157. Epub 2012 May 2.


Pseudomonas aeruginosa population structure revisited under environmental focus: impact of water quality and phage pressure.

Selezska K, Kazmierczak M, Müsken M, Garbe J, Schobert M, Häussler S, Wiehlmann L, Rohde C, Sikorski J.

Environ Microbiol. 2012 Aug;14(8):1952-67. doi: 10.1111/j.1462-2920.2012.02719.x. Epub 2012 Mar 6.


Bacterial hydrolysis of host glycoproteins - powerful protein modification and efficient nutrient acquisition.

Garbe J, Collin M.

J Innate Immun. 2012;4(2):121-31. doi: 10.1159/000334775. Epub 2012 Jan 3. Review.


Experimental study of a novel mechanical connector for sutureless open arterial anastomosis.

Abou Taam S, Garbé JF, Boufi M, Bossavy JP, Ricco JB.

J Vasc Surg. 2012 Jan;55(1):210-5. doi: 10.1016/j.jvs.2011.07.082. Epub 2011 Dec 3.


Forced degradation of therapeutic proteins.

Hawe A, Wiggenhorn M, van de Weert M, Garbe JH, Mahler HC, Jiskoot W.

J Pharm Sci. 2012 Mar;101(3):895-913. doi: 10.1002/jps.22812. Epub 2011 Nov 14. Review.


Cysteine proteinase SpeB from Streptococcus pyogenes - a potent modifier of immunologically important host and bacterial proteins.

Nelson DC, Garbe J, Collin M.

Biol Chem. 2011 Dec;392(12):1077-88. doi: 10.1515/BC.2011.208. Review.


Epigenetic regulation of normal human mammary cell type-specific miRNAs.

Vrba L, Garbe JC, Stampfer MR, Futscher BW.

Genome Res. 2011 Dec;21(12):2026-37. doi: 10.1101/gr.123935.111. Epub 2011 Aug 26.


Sequencing and characterization of Pseudomonas aeruginosa phage JG004.

Garbe J, Bunk B, Rohde M, Schobert M.

BMC Microbiol. 2011 May 14;11:102. doi: 10.1186/1471-2180-11-102.


Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells.

Chanson L, Brownfield D, Garbe JC, Kuhn I, Stampfer MR, Bissell MJ, LaBarge MA.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3264-9. doi: 10.1073/pnas.1019556108. Epub 2011 Feb 7.


Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system.

Carlson DF, Garbe JR, Tan W, Martin MJ, Dobrinsky JR, Hackett PB, Clark KJ, Fahrenkrug SC.

Transgenic Res. 2011 Oct;20(5):1125-37. doi: 10.1007/s11248-010-9481-7. Epub 2011 Jan 9.


Development and application of bovine and porcine oligonucleotide arrays with protein-based annotation.

Garbe JR, Elsik CG, Antoniou E, Reecy JM, Clark KJ, Venkatraman A, Kim JW, Schnabel RD, Michael Dickens C, Wolfinger RD, Fahrenkrug SC, Taylor JF.

J Biomed Biotechnol. 2010;2010:453638. doi: 10.1155/2010/453638. Epub 2010 Dec 14.


Characterization of JG024, a pseudomonas aeruginosa PB1-like broad host range phage under simulated infection conditions.

Garbe J, Wesche A, Bunk B, Kazmierczak M, Selezska K, Rohde C, Sikorski J, Rohde M, Jahn D, Schobert M.

BMC Microbiol. 2010 Nov 26;10:301. doi: 10.1186/1471-2180-10-301.


Primary cilium-dependent and -independent Hedgehog signaling inhibits p16(INK4A).

Bishop CL, Bergin AM, Fessart D, Borgdorff V, Hatzimasoura E, Garbe JC, Stampfer MR, Koh J, Beach DH.

Mol Cell. 2010 Nov 24;40(4):533-47. doi: 10.1016/j.molcel.2010.10.027.


Exon-level microarray analyses identify alternative splicing programs in breast cancer.

Lapuk A, Marr H, Jakkula L, Pedro H, Bhattacharya S, Purdom E, Hu Z, Simpson K, Pachter L, Durinck S, Wang N, Parvin B, Fontenay G, Speed T, Garbe J, Stampfer M, Bayandorian H, Dorton S, Clark TA, Schweitzer A, Wyrobek A, Feiler H, Spellman P, Conboy J, Gray JW.

Mol Cancer Res. 2010 Jul;8(7):961-74. doi: 10.1158/1541-7786.MCR-09-0528. Epub 2010 Jul 6.


Differential gene expression of ewes varying in tolerance to dietary nitrate.

Cockrum RR, Austin KJ, Kim JW, Garbe JR, Fahrenkrug SC, Taylor JF, Cammack KM.

J Anim Sci. 2010 Oct;88(10):3187-97. doi: 10.2527/jas.2009-2709. Epub 2010 Jun 18.


Anaerobic adaptation in Pseudomonas aeruginosa: definition of the Anr and Dnr regulons.

Trunk K, Benkert B, Quäck N, Münch R, Scheer M, Garbe J, Jänsch L, Trost M, Wehland J, Buer J, Jahn M, Schobert M, Jahn D.

Environ Microbiol. 2010 Jun;12(6):1719-33. doi: 10.1111/j.1462-2920.2010.02252.x.


Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition.

Carlson DF, Geurts AM, Garbe JR, Park CW, Rangel-Filho A, O'Grady SM, Jacob HJ, Steer CJ, Largaespada DA, Fahrenkrug SC.

Transgenic Res. 2011 Feb;20(1):29-45. doi: 10.1007/s11248-010-9386-5. Epub 2010 Mar 30.


Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells.

Vrba L, Jensen TJ, Garbe JC, Heimark RL, Cress AE, Dickinson S, Stampfer MR, Futscher BW.

PLoS One. 2010 Jan 13;5(1):e8697. doi: 10.1371/journal.pone.0008697.

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