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Items: 1 to 50 of 295

1.

A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease.

Villella VR, Venerando A, Cozza G, Esposito S, Ferrari E, Monzani R, Spinella MC, Oikonomou V, Renga G, Tosco A, Rossin F, Guido S, Silano M, Garaci E, Chao YK, Grimm C, Luciani A, Romani L, Piacentini M, Raia V, Kroemer G, Maiuri L.

EMBO J. 2019 Jan 15;38(2). pii: e100101. doi: 10.15252/embj.2018100101. Epub 2018 Nov 29.

2.

Thymosins in multiple sclerosis and its experimental models: moving from basic to clinical application.

Severa M, Zhang J, Giacomini E, Rizzo F, Etna MP, Cruciani M, Garaci E, Chopp M, Coccia EM.

Mult Scler Relat Disord. 2019 Jan;27:52-60. doi: 10.1016/j.msard.2018.09.035. Epub 2018 Oct 2. Review.

PMID:
30317071
3.

Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice.

Celestino I, Checconi P, Amatore D, De Angelis M, Coluccio P, Dattilo R, Alunni Fegatelli D, Clemente AM, Matarrese P, Torcia MG, Mancinelli R, Mammola CL, Garaci E, Vestri AR, Malorni W, Palamara AT, Nencioni L.

Front Immunol. 2018 Jul 30;9:1747. doi: 10.3389/fimmu.2018.01747. eCollection 2018.

4.

Transdifferentiation: a new promise for neurodegenerative diseases.

Mollinari C, Zhao J, Lupacchini L, Garaci E, Merlo D, Pei G.

Cell Death Dis. 2018 Aug 6;9(8):830. doi: 10.1038/s41419-018-0891-4.

5.

From thymus to cystic fibrosis: the amazing life of thymosin alpha 1.

Garaci E.

Expert Opin Biol Ther. 2018 Jul;18(sup1):9-11. doi: 10.1080/14712598.2018.1484447. No abstract available.

PMID:
30063868
6.

Cellular proteostasis: a new twist in the action of thymosin α1.

Stincardini C, Renga G, Villella V, Pariano M, Oikonomou V, Borghi M, Bellet MM, Sforna L, Costantini C, Goldstein AL, Garaci E, Romani L.

Expert Opin Biol Ther. 2018 Jul;18(sup1):43-48. doi: 10.1080/14712598.2018.1484103. Review.

PMID:
30063867
7.

Serum thymosin alpha 1 levels in normal and pathological conditions.

Pica F, Gaziano R, Casalinuovo IA, Moroni G, Buè C, Limongi D, D'Agostini C, Tomino C, Perricone R, Palamara AT, Sinibaldi Vallebona P, Garaci E.

Expert Opin Biol Ther. 2018 Jul;18(sup1):13-21. doi: 10.1080/14712598.2018.1474197. Review.

PMID:
30063864
8.

Deciphering cellular biological processes to clinical application: a new perspective for Tα1 treatment targeting multiple diseases.

Matteucci C, Argaw-Denboba A, Balestrieri E, Giovinazzo A, Miele M, D'Agostini C, Pica F, Grelli S, Paci M, Mastino A, Sinibaldi Vallebona P, Garaci E, Tomino C.

Expert Opin Biol Ther. 2018 Jul;18(sup1):23-31. doi: 10.1080/14712598.2018.1474198.

PMID:
30063863
9.

Potential mechanism of thymosin-α1-membrane interactions leading to pleiotropy: experimental evidence and hypotheses.

Mandaliti W, Nepravishta R, Pica F, Vallebona PS, Garaci E, Paci M.

Expert Opin Biol Ther. 2018 Jul;18(sup1):33-42. doi: 10.1080/14712598.2018.1456527. Review.

PMID:
30063856
10.

Thymosin β4 limits inflammation through autophagy.

Renga G, Oikonomou V, Stincardini C, Pariano M, Borghi M, Costantini C, Bartoli A, Garaci E, Goldstein AL, Romani L.

Expert Opin Biol Ther. 2018 Jul;18(sup1):171-175. doi: 10.1080/14712598.2018.1473854. Review.

PMID:
30063848
11.

Introduction for the Fifth International Symposium on Thymosins in Health and Disease.

Goldstein AL, Garaci E.

Expert Opin Biol Ther. 2018 Jul;18(sup1):1-3. doi: 10.1080/14712598.2018.1497606. No abstract available.

PMID:
29985661
12.

Reply to 'F508del-CFTR is not corrected by thymosin α1'.

Romani L, Stincardini C, Giovagnoli S, Paci M, Villella VR, Sforna L, Renga G, Bellet MM, Costantini C, Puccetti P, Kroemer G, Maiuri L, Pessia M, Goldstein A, Garaci E.

Nat Med. 2018 Jul;24(7):891-893. doi: 10.1038/s41591-018-0080-0. No abstract available.

PMID:
29942090
13.

Publisher Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.

Romani L, Oikonomou V, Moretti S, Iannitti RG, D'Adamo MC, Villella VR, Pariano M, Sforna L, Borghi M, Bellet MM, Fallarino F, Pallotta MT, Servillo G, Ferrari E, Puccetti P, Kroemer G, Pessia M, Maiuri L, Goldstein AL, Garaci E.

Nat Med. 2018 Sep;24(9):1482. doi: 10.1038/s41591-018-0099-2.

PMID:
29934535
14.

Author Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.

Romani L, Oikonomou V, Moretti S, Iannitti RG, D'Adamo MC, Villella VR, Pariano M, Sforna L, Borghi M, Bellet MM, Fallarino F, Pallotta MT, Servillo G, Ferrari E, Puccetti P, Kroemer G, Pessia M, Maiuri L, Goldstein AL, Garaci E.

Nat Med. 2018 Sep;24(9):1481. doi: 10.1038/s41591-018-0100-0.

PMID:
29934534
15.

IL-9 and Mast Cells Are Key Players of Candida albicans Commensalism and Pathogenesis in the Gut.

Renga G, Moretti S, Oikonomou V, Borghi M, Zelante T, Paolicelli G, Costantini C, De Zuani M, Villella VR, Raia V, Del Sordo R, Bartoli A, Baldoni M, Renauld JC, Sidoni A, Garaci E, Maiuri L, Pucillo C, Romani L.

Cell Rep. 2018 May 8;23(6):1767-1778. doi: 10.1016/j.celrep.2018.04.034.

16.

Thymosin α1 Interacts with Hyaluronic Acid Electrostatically by Its Terminal Sequence LKEKK.

Mandaliti W, Nepravishta R, Pica F, Vallebona PS, Garaci E, Paci M.

Molecules. 2017 Oct 27;22(11). pii: E1843. doi: 10.3390/molecules22111843.

17.

Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.

Romani L, Oikonomou V, Moretti S, Iannitti RG, D'Adamo MC, Villella VR, Pariano M, Sforna L, Borghi M, Bellet MM, Fallarino F, Pallotta MT, Servillo G, Ferrari E, Puccetti P, Kroemer G, Pessia M, Maiuri L, Goldstein AL, Garaci E.

Nat Med. 2017 May;23(5):590-600. doi: 10.1038/nm.4305. Epub 2017 Apr 10. Erratum in: Nat Med. 2018 Sep;24(9):1481. Nat Med. 2018 Sep;24(9):1482.

18.

Thymosin alpha 1 and HIV-1: recent advances and future perspectives.

Matteucci C, Grelli S, Balestrieri E, Minutolo A, Argaw-Denboba A, Macchi B, Sinibaldi-Vallebona P, Perno CF, Mastino A, Garaci E.

Future Microbiol. 2017 Feb;12:141-155. doi: 10.2217/fmb-2016-0125. Epub 2017 Jan 20. Review.

PMID:
28106477
19.

Herpes Simplex Virus-Type1 (HSV-1) Impairs DNA Repair in Cortical Neurons.

De Chiara G, Racaniello M, Mollinari C, Marcocci ME, Aversa G, Cardinale A, Giovanetti A, Garaci E, Palamara AT, Merlo D.

Front Aging Neurosci. 2016 Oct 18;8:242. eCollection 2016.

20.

Mechanism of Action of Thymosinα1: Does It Interact with Membrane by Recognition of Exposed Phosphatidylserine on Cell Surface? A Structural Approach.

Nepravishta R, Mandaliti W, Vallebona PS, Pica F, Garaci E, Paci M.

Vitam Horm. 2016;102:101-19. doi: 10.1016/bs.vh.2016.04.002. Epub 2016 May 24. Review.

PMID:
27450732
21.

Serum thymosin α 1 levels in patients with chronic inflammatory autoimmune diseases.

Pica F, Chimenti MS, Gaziano R, Buè C, Casalinuovo IA, Triggianese P, Conigliaro P, Di Carlo D, Cordero V, Adorno G, Volpi A, Perricone R, Garaci E.

Clin Exp Immunol. 2016 Oct;186(1):39-45. doi: 10.1111/cei.12833. Epub 2016 Aug 1.

22.

HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4(+) T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial.

Ensoli B, Nchabeleng M, Ensoli F, Tripiciano A, Bellino S, Picconi O, Sgadari C, Longo O, Tavoschi L, Joffe D, Cafaro A, Francavilla V, Moretti S, Pavone Cossut MR, Collacchi B, Arancio A, Paniccia G, Casabianca A, Magnani M, Buttò S, Levendal E, Ndimande JV, Asia B, Pillay Y, Garaci E, Monini P; SMU-MeCRU study group.

Retrovirology. 2016 Jun 9;13(1):34. doi: 10.1186/s12977-016-0261-1.

23.

DNA Double Strand Breaks: A Common Theme in Neurodegenerative Diseases.

Merlo D, Mollinari C, Racaniello M, Garaci E, Cardinale A.

Curr Alzheimer Res. 2016;13(11):1208-1218. Review.

PMID:
27033054
24.

Thymosin α1 Interacts with Exposed Phosphatidylserine in Membrane Models and in Cells and Uses Serum Albumin as a Carrier.

Mandaliti W, Nepravishta R, Sinibaldi Vallebona P, Pica F, Garaci E, Paci M.

Biochemistry. 2016 Mar 15;55(10):1462-72. doi: 10.1021/acs.biochem.5b01345. Epub 2016 Mar 3.

PMID:
26909491
25.

New studies about the insertion mechanism of Thymosin α1 in negative regions of model membranes as starting point of the bioactivity.

Mandaliti W, Nepravishta R, Sinibaldi Vallebona P, Pica F, Garaci E, Paci M.

Amino Acids. 2016 May;48(5):1231-9. doi: 10.1007/s00726-016-2169-4. Epub 2016 Jan 22.

PMID:
26801937
26.

Herpes Simplex Virus type-1 infection induces synaptic dysfunction in cultured cortical neurons via GSK-3 activation and intraneuronal amyloid-β protein accumulation.

Piacentini R, Li Puma DD, Ripoli C, Marcocci ME, De Chiara G, Garaci E, Palamara AT, Grassi C.

Sci Rep. 2015 Oct 21;5:15444. doi: 10.1038/srep15444.

27.

Introduction for the Fourth International Symposium on Thymosins in Health and Disease.

Garaci E, Goldstein AL.

Expert Opin Biol Ther. 2015;15 Suppl 1:S1-3. doi: 10.1517/14712598.2015.1044893.

PMID:
26169719
28.

Thymosin α1: burying secrets in the thymus.

Moretti S, Oikonomou V, Garaci E, Romani L.

Expert Opin Biol Ther. 2015;15 Suppl 1:S51-8. doi: 10.1517/14712598.2015.1044895. Epub 2015 Jun 22.

PMID:
26098878
29.

Historical review of thymosin α 1 in infectious diseases.

Camerini R, Garaci E.

Expert Opin Biol Ther. 2015;15 Suppl 1:S117-27. doi: 10.1517/14712598.2015.1033393. Epub 2015 Jun 22. Review.

PMID:
26098768
30.

Thymosin α1 modifies podosome architecture and promptly stimulates the expression of podosomal markers in mature macrophages.

Serafino A, Andreola F, Pittaluga E, Krasnowska EK, Nicotera G, Sferrazza G, Sinibaldi Vallebona P, Pierimarchi P, Garaci E.

Expert Opin Biol Ther. 2015;15 Suppl 1:S101-16. doi: 10.1517/14712598.2015.1024221. Epub 2015 Jun 22.

PMID:
26098689
31.

Dual effect of Thymosin α 1 on human monocyte-derived dendritic cell in vitro stimulated with viral and bacterial toll-like receptor agonists.

Giacomini E, Severa M, Cruciani M, Etna MP, Rizzo F, Pardini M, Scagnolari C, Garaci E, Coccia EM.

Expert Opin Biol Ther. 2015;15 Suppl 1:S59-70. doi: 10.1517/14712598.2015.1019460. Epub 2015 Jun 22.

PMID:
26096650
32.

Historical review on thymosin α1 in oncology: preclinical and clinical experiences.

Garaci E, Pica F, Matteucci C, Gaziano R, D'Agostini C, Miele MT, Camerini R, Palamara AT, Favalli C, Mastino A, Serafino A, Sinibaldi Vallebona P.

Expert Opin Biol Ther. 2015;15 Suppl 1:S31-9. doi: 10.1517/14712598.2015.1017466. Epub 2015 Jun 22. Review.

PMID:
26096345
33.

Thymosin α 1 potentiates the release by CD8(+) cells of soluble factors able to inhibit HIV-1 and human T lymphotropic virus 1 infection in vitro.

Matteucci C, Minutolo A, Pollicita M, Balestrieri E, Grelli S, D'Ettorre G, Vullo V, Bucci I, Luchini A, Aquaro S, Sinibaldi-Vallebona P, Macchi B, Perno CF, Mastino A, Garaci E.

Expert Opin Biol Ther. 2015;15 Suppl 1:S83-100. doi: 10.1517/14712598.2015.1021677. Epub 2015 Jun 22.

PMID:
26094546
34.

Herpes simplex virus type 1 infection in neurons leads to production and nuclear localization of APP intracellular domain (AICD): implications for Alzheimer's disease pathogenesis.

Civitelli L, Marcocci ME, Celestino I, Piacentini R, Garaci E, Grassi C, De Chiara G, Palamara AT.

J Neurovirol. 2015 Oct;21(5):480-90. doi: 10.1007/s13365-015-0344-0. Epub 2015 Apr 30.

PMID:
25925093
35.

HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial.

Ensoli F, Cafaro A, Casabianca A, Tripiciano A, Bellino S, Longo O, Francavilla V, Picconi O, Sgadari C, Moretti S, Cossut MR, Arancio A, Orlandi C, Sernicola L, Maggiorella MT, Paniccia G, Mussini C, Lazzarin A, Sighinolfi L, Palamara G, Gori A, Angarano G, Di Pietro M, Galli M, Mercurio VS, Castelli F, Di Perri G, Monini P, Magnani M, Garaci E, Ensoli B.

Retrovirology. 2015 Apr 29;12:33. doi: 10.1186/s12977-015-0151-y.

36.

Thymosin α1 inserts N terminus into model membranes assuming a helical conformation.

Nepravishta R, Mandaliti W, Eliseo T, Sinibaldi Vallebona P, Pica F, Garaci E, Paci M.

Expert Opin Biol Ther. 2015;15 Suppl 1:S71-81. doi: 10.1517/14712598.2015.1009034. Epub 2015 Feb 2.

PMID:
25642593
37.

miR-34a regulates cell proliferation, morphology and function of newborn neurons resulting in improved behavioural outcomes.

Mollinari C, Racaniello M, Berry A, Pieri M, de Stefano MC, Cardinale A, Zona C, Cirulli F, Garaci E, Merlo D.

Cell Death Dis. 2015 Jan 29;6:e1622. doi: 10.1038/cddis.2014.589.

38.

Intracellular redox state as target for anti-influenza therapy: are antioxidants always effective?

Sgarbanti R, Amatore D, Celestino I, Marcocci ME, Fraternale A, Ciriolo MR, Magnani M, Saladino R, Garaci E, Palamara AT, Nencioni L.

Curr Top Med Chem. 2014;14(22):2529-41. Review.

39.

Biochemical characterization of sirtuin 6 in the brain and its involvement in oxidative stress response.

Cardinale A, de Stefano MC, Mollinari C, Racaniello M, Garaci E, Merlo D.

Neurochem Res. 2015 Jan;40(1):59-69. doi: 10.1007/s11064-014-1465-1. Epub 2014 Nov 1.

PMID:
25366464
40.

Influenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS.

Amatore D, Sgarbanti R, Aquilano K, Baldelli S, Limongi D, Civitelli L, Nencioni L, Garaci E, Ciriolo MR, Palamara AT.

Cell Microbiol. 2015 Jan;17(1):131-45. doi: 10.1111/cmi.12343. Epub 2014 Oct 7.

41.

HSV-1 and Alzheimer's disease: more than a hypothesis.

Piacentini R, De Chiara G, Li Puma DD, Ripoli C, Marcocci ME, Garaci E, Palamara AT, Grassi C.

Front Pharmacol. 2014 May 7;5:97. doi: 10.3389/fphar.2014.00097. eCollection 2014. Review.

42.

A candidate anti-HIV reservoir compound, auranofin, exerts a selective 'anti-memory' effect by exploiting the baseline oxidative status of lymphocytes.

Chirullo B, Sgarbanti R, Limongi D, Shytaj IL, Alvarez D, Das B, Boe A, DaFonseca S, Chomont N, Liotta L, Petricoin EI, Norelli S, Pelosi E, Garaci E, Savarino A, Palamara AT.

Cell Death Dis. 2013 Dec 5;4:e944. doi: 10.1038/cddis.2013.473.

43.

Human endogenous retroviruses and ADHD.

Balestrieri E, Pitzianti M, Matteucci C, D'Agati E, Sorrentino R, Baratta A, Caterina R, Zenobi R, Curatolo P, Garaci E, Sinibaldi-Vallebona P, Pasini A.

World J Biol Psychiatry. 2014 Aug;15(6):499-504. doi: 10.3109/15622975.2013.862345. Epub 2013 Nov 28.

PMID:
24286278
44.

Detection of high levels of Survivin-immunoglobulin M immune complex in sera from hepatitis C virus infected patients with cirrhosis.

Matteucci C, Sorrentino R, Bellis L, Ettorre GM, Svicher V, Santoro R, Vennarecci G, Biasiolo A, Pontisso P, Scacciatelli D, Beneduce L, Sarrecchia C, Casalino P, Bernardini S, Pierimarchi P, Garaci E, Puoti C, Rasi G.

Hepatol Res. 2014 Sep;44(9):1008-18. doi: 10.1111/hepr.12239. Epub 2013 Dec 19.

45.

Analysis of urinary human growth hormone (hGH) using hydrogel nanoparticles and isoform differential immunoassays after short recombinant hGH treatment: preliminary results.

Bosch J, Luchini A, Pichini S, Tamburro D, Fredolini C, Liotta L, Petricoin E, Pacifici R, Facchiano F, Segura J, Garaci E, Gutiérrez-Gallego R.

J Pharm Biomed Anal. 2013 Nov;85:194-7. doi: 10.1016/j.jpba.2013.07.028. Epub 2013 Aug 1.

46.

Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS.

Shytaj IL, Chirullo B, Wagner W, Ferrari MG, Sgarbanti R, Corte AD, LaBranche C, Lopalco L, Palamara AT, Montefiori D, Lewis MG, Garaci E, Savarino A.

Retrovirology. 2013 Jul 16;10:71. doi: 10.1186/1742-4690-10-71.

47.

Thymosin α1 activates complement receptor-mediated phagocytosis in human monocyte-derived macrophages.

Serafino A, Pica F, Andreola F, Gaziano R, Moroni N, Moroni G, Zonfrillo M, Pierimarchi P, Sinibaldi-Vallebona P, Garaci E.

J Innate Immun. 2014;6(1):72-88. doi: 10.1159/000351587. Epub 2013 Jun 22.

48.

Modulation of the immune and inflammatory responses by Plasmodium falciparum schizont extracts: role of myeloid dendritic cells in effector and regulatory functions of CD4+ lymphocytes.

Clemente AM, Fadigati G, Caporale R, Marchese DG, Castronovo G, Sannella AR, Severini C, Verra F, Garaci E, Cozzolino F, Torcia MG.

Infect Immun. 2013 May;81(5):1842-51. doi: 10.1128/IAI.01226-12. Epub 2013 Mar 18.

49.

Interplay between Hepatitis C Virus and Redox Cell Signaling.

Ruggieri A, Anticoli S, Nencioni L, Sgarbanti R, Garaci E, Palamara AT.

Int J Mol Sci. 2013 Feb 26;14(3):4705-21. doi: 10.3390/ijms14034705.

50.

The Environmental Pollutant Cadmium Promotes Influenza Virus Replication in MDCK Cells by Altering Their Redox State.

Checconi P, Sgarbanti R, Celestino I, Limongi D, Amatore D, Iuvara A, Alimonti A, Garaci E, Palamara AT, Nencioni L.

Int J Mol Sci. 2013 Feb 19;14(2):4148-62. doi: 10.3390/ijms14024148.

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