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Items: 1 to 50 of 125

1.

The long noncoding RNA CHROME regulates cholesterol homeostasis in primate.

Hennessy EJ, van Solingen C, Scacalossi KR, Ouimet M, Afonso MS, Prins J, Koelwyn GJ, Sharma M, Ramkhelawon B, Carpenter S, Busch A, Chernogubova E, Matic LP, Hedin U, Maegdefessel L, Caffrey BE, Hussein MA, Ricci EP, Temel RE, Garabedian MJ, Berger JS, Vickers KC, Kanke M, Sethupathy P, Teupser D, Holdt LM, Moore KJ.

Nat Metab. 2019 Jan;1(1):98-110. doi: 10.1038/s42255-018-0004-9. Epub 2018 Dec 3.

2.

Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors.

Arango-Lievano M, Borie AM, Dromard Y, Murat M, Desarmenien MG, Garabedian MJ, Jeanneteau F.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13097-13106. doi: 10.1073/pnas.1903203116. Epub 2019 Jun 10.

3.

Prostate-specific loss of UXT promotes cancer progression.

Wang Y, Schafler ED, Thomas PA, Ha S, David G, Adney E, Garabedian MJ, Lee P, Logan SK.

Oncotarget. 2019 Jan 22;10(7):707-716. doi: 10.18632/oncotarget.26573. eCollection 2019 Jan 22.

4.

Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease.

Becares N, Gage MC, Voisin M, Shrestha E, Martin-Gutierrez L, Liang N, Louie R, Pourcet B, Pello OM, Luong TV, Goñi S, Pichardo-Almarza C, Røberg-Larsen H, Diaz-Zuccarini V, Steffensen KR, O'Brien A, Garabedian MJ, Rombouts K, Treuter E, Pineda-Torra I.

Cell Rep. 2019 Jan 22;26(4):984-995.e6. doi: 10.1016/j.celrep.2018.12.094.

5.

Bridging the Gap between Brain-Derived Neurotrophic Factor and Glucocorticoid Effects on Brain Networks.

Jeanneteau F, Borie A, Chao MV, Garabedian MJ.

Neuroendocrinology. 2019;109(3):277-284. doi: 10.1159/000496392. Epub 2018 Dec 20. Review.

PMID:
30572337
6.

Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer.

Schneider JA, Craven TW, Kasper AC, Yun C, Haugbro M, Briggs EM, Svetlov V, Nudler E, Knaut H, Bonneau R, Garabedian MJ, Kirshenbaum K, Logan SK.

Nat Commun. 2018 Oct 23;9(1):4396. doi: 10.1038/s41467-018-06845-3.

7.

The mediator complex in genomic and non-genomic signaling in cancer.

Weber H, Garabedian MJ.

Steroids. 2018 May;133:8-14. doi: 10.1016/j.steroids.2017.11.007. Epub 2017 Nov 21. Review.

8.

Glucocorticoid receptor action in metabolic and neuronal function.

Garabedian MJ, Harris CA, Jeanneteau F.

F1000Res. 2017 Jul 24;6:1208. doi: 10.12688/f1000research.11375.1. eCollection 2017. Review.

9.

URI Regulates KAP1 Phosphorylation and Transcriptional Repression via PP2A Phosphatase in Prostate Cancer Cells.

Mita P, Savas JN, Briggs EM, Ha S, Gnanakkan V, Yates JR 3rd, Robins DM, David G, Boeke JD, Garabedian MJ, Logan SK.

J Biol Chem. 2016 Dec 2;291(49):25516-25528. Epub 2016 Oct 25.

10.

PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity.

Basu-Roy U, Han E, Rattanakorn K, Gadi A, Verma N, Maurizi G, Gunaratne PH, Coarfa C, Kennedy OD, Garabedian MJ, Basilico C, Mansukhani A.

Oncotarget. 2016 Sep 20;7(38):60954-60970. doi: 10.18632/oncotarget.11273.

11.

Multivalent Peptoid Conjugates Which Overcome Enzalutamide Resistance in Prostate Cancer Cells.

Wang Y, Dehigaspitiya DC, Levine PM, Profit AA, Haugbro M, Imberg-Kazdan K, Logan SK, Kirshenbaum K, Garabedian MJ.

Cancer Res. 2016 Sep 1;76(17):5124-32. doi: 10.1158/0008-5472.CAN-16-0385. Epub 2016 Aug 3.

12.

Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation.

Savic D, Ramaker RC, Roberts BS, Dean EC, Burwell TC, Meadows SK, Cooper SJ, Garabedian MJ, Gertz J, Myers RM.

Genome Med. 2016 Jul 11;8(1):74. doi: 10.1186/s13073-016-0328-6.

13.

Dynein axonemal heavy chain 8 promotes androgen receptor activity and associates with prostate cancer progression.

Wang Y, Ledet RJ, Imberg-Kazdan K, Logan SK, Garabedian MJ.

Oncotarget. 2016 Aug 2;7(31):49268-49280. doi: 10.18632/oncotarget.10284.

14.

Poly(ADP-ribose) Polymerase 1 Represses Liver X Receptor-mediated ABCA1 Expression and Cholesterol Efflux in Macrophages.

Shrestha E, Hussein MA, Savas JN, Ouimet M, Barrett TJ, Leone S, Yates JR 3rd, Moore KJ, Fisher EA, Garabedian MJ.

J Biol Chem. 2016 May 20;291(21):11172-84. doi: 10.1074/jbc.M116.726729. Epub 2016 Mar 29.

15.

miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux.

Ouimet M, Hennessy EJ, van Solingen C, Koelwyn GJ, Hussein MA, Ramkhelawon B, Rayner KJ, Temel RE, Perisic L, Hedin U, Maegdefessel L, Garabedian MJ, Holdt LM, Teupser D, Moore KJ.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):942-951. doi: 10.1161/ATVBAHA.116.307282. Epub 2016 Mar 3.

16.

Randomized, Double-Blinded Trial of Magnesium Sulfate Tocolysis versus Intravenous Normal Saline for Preterm Nonsevere Placental Abruption.

Colón I, Berletti M, Garabedian MJ, Wilcox N, Williams K, El-Sayed YY, Chueh J.

Am J Perinatol. 2016 Jun;33(7):696-702. doi: 10.1055/s-0036-1571324. Epub 2016 Feb 12.

PMID:
26871905
17.

Neurotrophic-priming of glucocorticoid receptor signaling is essential for neuronal plasticity to stress and antidepressant treatment.

Arango-Lievano M, Lambert WM, Bath KG, Garabedian MJ, Chao MV, Jeanneteau F.

Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15737-42. doi: 10.1073/pnas.1509045112. Epub 2015 Nov 16.

18.

URI1 amplification in uterine carcinosarcoma associates with chemo-resistance and poor prognosis.

Wang Y, Garabedian MJ, Logan SK.

Am J Cancer Res. 2015 Jun 15;5(7):2320-9. eCollection 2015.

19.

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.

Jones CL, Gearheart CM, Fosmire S, Delgado-Martin C, Evensen NA, Bride K, Waanders AJ, Pais F, Wang J, Bhatla T, Bitterman DS, de Rijk SR, Bourgeois W, Dandekar S, Park E, Burleson TM, Madhusoodhan PP, Teachey DT, Raetz EA, Hermiston ML, Müschen M, Loh ML, Hunger SP, Zhang J, Garabedian MJ, Porter CC, Carroll WL.

Blood. 2015 Nov 5;126(19):2202-12. doi: 10.1182/blood-2015-04-639138. Epub 2015 Aug 31.

20.

LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.

Hussein MA, Shrestha E, Ouimet M, Barrett TJ, Leone S, Moore KJ, Hérault Y, Fisher EA, Garabedian MJ.

PLoS One. 2015 Aug 19;10(8):e0135218. doi: 10.1371/journal.pone.0135218. eCollection 2015.

21.

Current knowledge of prenatal diagnosis of mosaic autosomal trisomy in amniocytes: karyotype/phenotype correlations.

Wallerstein R, Misra S, Dugar RB, Alem M, Mazzoni R, Garabedian MJ.

Prenat Diagn. 2015 Sep;35(9):841-7. doi: 10.1002/pd.4620. Epub 2015 Jun 23. Review.

PMID:
25976239
22.

Modulation of Macrophage Gene Expression via Liver X Receptor α Serine 198 Phosphorylation.

Wu C, Hussein MA, Shrestha E, Leone S, Aiyegbo MS, Lambert WM, Pourcet B, Cardozo T, Gustafson JA, Fisher EA, Pineda-Torra I, Garabedian MJ.

Mol Cell Biol. 2015 Jun 1;35(11):2024-34. doi: 10.1128/MCB.00985-14. Epub 2015 Mar 30.

23.

In reply.

Girsen AI, Osmundson SS, Garabedian MJ, Naqvi M, Lyell DJ.

Obstet Gynecol. 2015 Mar;125(3):740. doi: 10.1097/AOG.0000000000000712. No abstract available.

PMID:
25730244
24.

Risk factors for classical hysterotomy in twin pregnancies.

Osmundson SS, Garabedian MJ, Yeaton-Massey A, Lyell DJ.

Obstet Gynecol. 2015 Mar;125(3):643-8. doi: 10.1097/AOG.0000000000000693.

25.

Body mass index and operative times at cesarean delivery.

Girsen AI, Osmundson SS, Naqvi M, Garabedian MJ, Lyell DJ.

Obstet Gynecol. 2014 Oct;124(4):684-9. doi: 10.1097/AOG.0000000000000462.

26.

A new model for providing cell-free DNA and risk assessment for chromosome abnormalities in a public hospital setting.

Wallerstein R, Jelks A, Garabedian MJ.

J Pregnancy. 2014;2014:962720. doi: 10.1155/2014/962720. Epub 2014 Jul 2.

27.

Maternal proteinuria in twin compared with singleton pregnancies.

Osmundson SS, Lafayette RA, Bowen RA, Roque VC, Garabedian MJ, Aziz N.

Obstet Gynecol. 2014 Aug;124(2 Pt 1):332-7. doi: 10.1097/AOG.0000000000000383.

PMID:
25004349
28.

Targeting the androgen receptor with steroid conjugates.

Levine PM, Garabedian MJ, Kirshenbaum K.

J Med Chem. 2014 Oct 23;57(20):8224-37. doi: 10.1021/jm500101h. Epub 2014 Jul 8. Review.

29.

Loss of TBL1XR1 disrupts glucocorticoid receptor recruitment to chromatin and results in glucocorticoid resistance in a B-lymphoblastic leukemia model.

Jones CL, Bhatla T, Blum R, Wang J, Paugh SW, Wen X, Bourgeois W, Bitterman DS, Raetz EA, Morrison DJ, Teachey DT, Evans WE, Garabedian MJ, Carroll WL.

J Biol Chem. 2014 Jul 25;289(30):20502-15.

30.

Caveolin-1 regulates genomic action of the glucocorticoid receptor in neural stem cells.

Peffer ME, Chandran UR, Luthra S, Volonte D, Galbiati F, Garabedian MJ, Monaghan AP, DeFranco DB.

Mol Cell Biol. 2014 Jul;34(14):2611-23.

31.

Glucocorticoids in laryngology: a review.

Rafii B, Sridharan S, Taliercio S, Govil N, Paul B, Garabedian MJ, Amin MR, Branski RC.

Laryngoscope. 2014 Jul;124(7):1668-73. doi: 10.1002/lary.24556. Epub 2014 Jan 28. Review.

PMID:
24474440
32.

Antenatal detection of maternal unipartental disomy of chromosome 2 in a fetus with non-chromosomal, non-syndromic alobar holoprosencephaly.

Quintana A, Garabedian MJ, Wallerstein RJ.

Am J Med Genet A. 2014 Jan;164A(1):276-8. doi: 10.1002/ajmg.a.36204. Epub 2013 Nov 15. No abstract available.

PMID:
24243683
33.

Risk factors for classical hysterotomy by gestational age.

Osmundson SS, Garabedian MJ, Lyell DJ.

Obstet Gynecol. 2013 Oct;122(4):845-50. doi: 10.1097/AOG.0b013e3182a39731.

PMID:
24084543
34.

Inhibition of androgen receptor and β-catenin activity in prostate cancer.

Lee E, Madar A, David G, Garabedian MJ, Dasgupta R, Logan SK.

Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15710-5. doi: 10.1073/pnas.1218168110. Epub 2013 Sep 9.

35.

Brain-derived neurotrophic factor signaling rewrites the glucocorticoid transcriptome via glucocorticoid receptor phosphorylation.

Lambert WM, Xu CF, Neubert TA, Chao MV, Garabedian MJ, Jeanneteau FD.

Mol Cell Biol. 2013 Sep;33(18):3700-14. doi: 10.1128/MCB.00150-13. Epub 2013 Jul 22. Erratum in: Mol Cell Biol. 2013 Oct;33(20):4138.

36.

Expression of androgen receptor and its phosphorylated forms in breast cancer progression.

Ren Q, Zhang L, Ruoff R, Ha S, Wang J, Jain S, Reuter V, Gerald W, Giri DD, Melamed J, Garabedian MJ, Lee P, Logan SK.

Cancer. 2013 Jul 15;119(14):2532-40. doi: 10.1002/cncr.28092. Epub 2013 Apr 19.

37.

Uptake of noninvasive prenatal testing (NIPT) in women following positive aneuploidy screening.

Chetty S, Garabedian MJ, Norton ME.

Prenat Diagn. 2013 Jun;33(6):542-6. doi: 10.1002/pd.4125.

PMID:
23592525
38.

A genome-wide RNA interference screen identifies new regulators of androgen receptor function in prostate cancer cells.

Imberg-Kazdan K, Ha S, Greenfield A, Poultney CS, Bonneau R, Logan SK, Garabedian MJ.

Genome Res. 2013 Apr;23(4):581-91. doi: 10.1101/gr.144774.112. Epub 2013 Feb 12.

39.

Up-regulation of oxytocin receptor expression at term is related to maternal body mass index.

Garabedian MJ, Hansen WF, McCord LA, Manning MA, O'Brien JM, Curry TE Jr.

Am J Perinatol. 2013 Jun;30(6):491-7. doi: 10.1055/s-0032-1329179. Epub 2013 Jan 25.

PMID:
23355275
40.

Pregnancy outcome in a woman with prune belly syndrome.

Hillman RT, Garabedian MJ, Wallerstein RJ.

BMJ Case Rep. 2012 Nov 30;2012. pii: bcr-2012-006490. doi: 10.1136/bcr-2012-006490.

41.

Prenatal Diagnosis of Cystic Hygroma related to a Deletion of 16q24.1 with Haploinsufficiency of FOXF1 and FOXC2 Genes.

Garabedian MJ, Wallerstein D, Medina N, Byrne J, Wallerstein RJ.

Case Rep Genet. 2012;2012:490408. doi: 10.1155/2012/490408. Epub 2012 Aug 28.

42.

Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner.

Gertz J, Reddy TE, Varley KE, Garabedian MJ, Myers RM.

Genome Res. 2012 Nov;22(11):2153-62. doi: 10.1101/gr.135681.111. Epub 2012 Sep 26.

43.

Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer.

Ha S, Iqbal NJ, Mita P, Ruoff R, Gerald WL, Lepor H, Taneja SS, Lee P, Melamed J, Garabedian MJ, Logan SK.

Oncogene. 2013 Aug 22;32(34):3992-4000. doi: 10.1038/onc.2012.412. Epub 2012 Sep 17.

44.

Androgen receptor antagonism by divalent ethisterone conjugates in castrate-resistant prostate cancer cells.

Levine PM, Lee E, Greenfield A, Bonneau R, Logan SK, Garabedian MJ, Kirshenbaum K.

ACS Chem Biol. 2012 Oct 19;7(10):1693-701. doi: 10.1021/cb300332w. Epub 2012 Aug 7.

45.

Mifepristone inhibits GRβ coupled prostate cancer cell proliferation.

Ligr M, Li Y, Logan SK, Taneja S, Melamed J, Lepor H, Garabedian MJ, Lee P.

J Urol. 2012 Sep;188(3):981-8. doi: 10.1016/j.juro.2012.04.102. Epub 2012 Jul 21.

46.

The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes.

Reddy TE, Gertz J, Crawford GE, Garabedian MJ, Myers RM.

Mol Cell Biol. 2012 Sep;32(18):3756-67. doi: 10.1128/MCB.00062-12. Epub 2012 Jul 16.

47.

Regression of atherosclerosis is characterized by broad changes in the plaque macrophage transcriptome.

Feig JE, Vengrenyuk Y, Reiser V, Wu C, Statnikov A, Aliferis CF, Garabedian MJ, Fisher EA, Puig O.

PLoS One. 2012;7(6):e39790. doi: 10.1371/journal.pone.0039790. Epub 2012 Jun 27.

48.

Multivalent peptidomimetic conjugates: a versatile platform for modulating androgen receptor activity.

Levine PM, Imberg K, Garabedian MJ, Kirshenbaum K.

J Am Chem Soc. 2012 Apr 25;134(16):6912-5. doi: 10.1021/ja300170n. Epub 2012 Apr 17.

PMID:
22509763
49.

Ligand structural motifs can decouple glucocorticoid receptor transcriptional activation from target promoter occupancy.

Blind RD, Pineda-Torra I, Xu Y, Xu HE, Garabedian MJ.

Biochem Biophys Res Commun. 2012 Apr 20;420(4):839-44. doi: 10.1016/j.bbrc.2012.03.084. Epub 2012 Mar 23.

50.

BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus.

Jeanneteau FD, Lambert WM, Ismaili N, Bath KG, Lee FS, Garabedian MJ, Chao MV.

Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1305-10. doi: 10.1073/pnas.1114122109. Epub 2012 Jan 9.

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